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Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt

Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

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Page 1: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

MycotoxinsinPoultryfeeds

ElsayedMickdamSouthValleyUniversity,FacultyofVeterinaryMedicine,

Qena,Egypt

Page 2: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

Mycotoxinsq Definitions:

Mycotoxins are a diverse group of toxic secondary metabolites produced by certain moulds when they grow on agricultural products under certain condition

q Mycotoxicoses : Disease condition caused by consumption of contaminated

feed with Mycotoxins.

q Mycotoxins are not essential for mould growth.

q According to FAO about 25% of the world’s crop harvests are contaminated by Mycotoxins.

SouthValleyUniversityFacultyOfVeterinaryMedicine

Page 3: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

BriefHistoryofMycotoxinandMycotoxicoses

•  Horses in the Soviet Union from 1931 to 1940 (stachybotryotoxicosis due to feeding moldy hay).

•  1940 to 1950, several deaths of poultry in

USA (due to feeding moldy feed)

SouthValleyUniversityFacultyOfVeterinaryMedicine

Page 4: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

•  In 1960, a dramatic mycotoxicosis of turkeys occurred in England called turkey X disease

•  Aflatoxin was discovered as the etiological agent

of this disease.

SouthValleyUniversityFacultyOfVeterinaryMedicine

BriefHistoryofMycotoxinandMycotoxicoses

Page 5: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

•  In the last 27 years, ochratoxin A, trichothecenes, deoxynivalenol and nivalenol were shown to be etiological agents for mycotoxicoses of man and livestock.

BriefHistoryofMycotoxinandMycotoxicoses

SouthValleyUniversityFacultyOfVeterinaryMedicine

Page 6: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

Mycotoxins

SouthValleyUniversityFacultyOfVeterinaryMedicine

•  Chemical compounds produced by some fungi •  Contaminate grains, food, and feed worldwide •  Aflatoxins were the first mycotoxins discovered

•  Hundreds now known worldwide •  30 are significant health hazards

•  5 principle mycotoxins affect cereal grains (corn, wheat, rye, barley, oats) •  aflatoxins, fumonisins, ochratoxin A,

deoxynivalenol (vomitoxin), and zearalenone

Gibberella ear rot caused by Fusarium graminearum (Gibberella zeae ) Source: Pioneer Hi-Bred, Intl

Fusarium head blight http://www.ars.usda.gov/Main/docs.htm?docid=9765

Page 7: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

CycleofFungalDisease

SouthValleyUniversityFacultyOfVeterinaryMedicine

Page 8: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

SouthValleyUniversityFacultyOfVeterinaryMedicine

Amlaninterna+onalmycotoxinsandpoultryareviewforpoultryproducers

Page 9: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

Thecase

q DifferentfarmsinDeltaregionEgypt

SouthValleyUniversityFacultyOfVeterinaryMedicine

Page 10: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

Thecase

Case History •  20-25 days old chicks (15000 bird) •  Birds suffer from decrease feed intake with poor conversion •  Decreased feed consumption •  Increase mortality •  Paralysis and lameness. •  Characteristic mouth lesions

SouthValleyUniversityFacultyOfVeterinaryMedicine

Page 11: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

q Liver and kidneys were enlarged and pale. q Shrunken firm nodular liver

SouthValleyUniversityFacultyOfVeterinaryMedicine

PM

Page 12: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

q Bile distended gall bladder and hemorrhages

SouthValleyUniversityFacultyOfVeterinaryMedicine

PM

Page 13: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

Treatment

SouthValleyUniversityFacultyOfVeterinaryMedicine

Prevent further exposure

Changing of the diet

Using mycotoxin

binder

improvement in body weight, Reduction in F.C.R. & Decline in mortality rate

Page 14: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:
Page 15: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:
Page 16: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:
Page 17: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions:

References•  Ramos Girona, A. J., Sillué, S. M., & Almenar, V. S. (2011).

Micotoxinas.Introducciónhistórica.RamosGironaAJ(ed.).•  Micotoxinas y micotoxicosis, Madrid, AMV Ediciones, 1-18.

Bakırdere, S.,Bora, S.,Bakırdere,E.,Aydın, F.,Arslan,Y.,Komesli,O., et al. (2012). Aflatoxin species: their health effects anddetermina+onmethodsindifferentfood-stuffs.

•  Central European JournalofChemistry, 10(3), 675-85.Atanda, S.A., Aina, J. A., Agoda, S. A., & U. OE, P. PO. (2012). MycotoxinManage-ment inAgriculture:aReview. JournalofAnimalScienceAdvances, 2(Suppl. 3.1), 250-60. [4] Moss, M. O. (1996).Mycotoxins.MycologicalResearch,100(5),513-23

•  Akande, K., Abubakar, M., Adegbola, T., & Bogoro, S. (2006).Nutri+onalandhealthimplica+onsofmycotoxinsinanimalfeeds:Areview.PakistanJournalofNutri+on,5(5),398-403.

Page 18: Mycotoxins in Poultry feeds · 2017. 10. 3. · Mycotoxins in Poultry feeds Elsayed Mickdam South Valley University, Faculty of Veterinary Medicine, Qena, Egypt Mycotoxins q Definitions: