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T.SASIDHARBVN 09062

AFLATOXICOSISAflatoxicosis is a gastrointestinal disease that affects all species of poultry.Young birds - more susceptible.Ducklings - highly susceptible.Quails - resistant to Aflatoxicosis.

INTRODUCTIONAspergillus flavus,A.parasiticus,Penicillium puberulumB, B, G,GAflatoxicol, flatoxitrem and cyclopiazonic acid are other toxic metabolites produced by these fungi on mouldy corn

ETIOLOGYImproper storage of feed or grains.Drought and insect damage to grain increase susceptibility of grain to fungal growthOptimum temperature for aflatoxin production by the fungus is tropical and subtropical where the temperature is 32-35c and high humidity.

TERATOGENICITYMUTAGENECITYCARCINOGENECITYHYPOPROTEINEMIADEATHPATHOGENESIS

Due to reduction in the size of spleen, thymus, bursa of Fabricius.Decreases both antibody-mediated and cell-mediated immunity.Increases severity of caecal coccidiosis, MD, E.Coli infection, Salmonellosis, Gumboro disease.Vaccination failures.Breeders- passive maternal immunity

Immunosuppression Bloody thigh syndrome Haemorrhage due to decreased clotting factor synthesis and increased fragility of minute blood vessels.Lazy leukocyte syndrome Toxic for B-lymphocytes and reduces blood phagocytes. DECREASES AVAILABILITY OF BILE SALTSVITAMIN-D3 & A DEFICIENCYDECREASED BLOOD CALCIUM LEVELDECREASED BONE STRENGTH DECREASED TOCOPHEROL LEVELVIT- A & E DEFICIENCYEFFECT OF AFLATOXIN IN POULTRY

Turkey poults -