My M.tech (Chemical) Drugs&Pharmaceutical Certficates

8/6/2019 My M.tech (Chemical) Drugs&Pharmaceutical Certficates

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Techno-Economic Feasibility Report on Manufacturing of Tablet Dosage

FormThesis Submitted To

Dr. BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY

In the partial fulfillment of requirement for

the award of degree of

MASTER OF TECHNOLOGY

In

[DRUGS AND PHARMACEUTICALS]

By

Mr. DULAL MAHAVIR MOHATO

Under the guidance of

Dr. P. S. WAKTE

Reader

ISO 9001-2008 Certified

DEPARTMENT OF CHEMICAL TECHNOLOGY,

Dr. BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY,

AURANGABAD-431004.

2011


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Dr. Babasaheb Ambedkar Marathwada University,

Aurangabad

NAAC Accredited B+

Department of Chemical Technology

ISO 9001:2008 Certified

Faculty of Engineering & Technology

University Campus, Aurangabad.

CERTIFICATE

This is to certify that the thesis entitled Techno-Economic Feasibility Report

on Manufacturing of Tablet Dosage Form is a bonafide work ofMr. DULAL

MAHAVIR MOHATO submitted to the Department of Chemical Technology,

Dr. Babasaheb Ambedkar Marathwada University, Aurangabad in the partial

fulfillment of the requirement for the Master of Technology (Chemical) [Drugs

& Pharmaceuticals].

Place:Aurangabad Dr. Devanand B. Shinde

Date: Professor and Head


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Dr. Babasaheb Ambedkar Marathwada University,

Aurangabad

NAAC Accredited B+

Department of Chemical Technology

ISO 9001:2008 Certified

Faculty of Engineering & Technology

University Campus, Aurangabad.

CANDIDATES DECLARATION

I submit this thesis entitled Techno-Economic Feasibility Report on

Manufacturing of Tablet Dosage Form in partial fulfillment for the Master of

Technology (Chemical) [Drugs & Pharmaceuticals] to Dr. Babasaheb

Ambedkar Marathwada University, Aurangabad. I hereby declare that the

project or part thereof has not been previously submitted by me.

Place:Aurangabad. Mr. DULAL M. MOHATO

Date:


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ACKNOWLEDGEMENT

I take this opportunity with much pleasure to thank all the people who

have helped me through the course of my journey towards producing this thesis.

I express my deep sense of gratitude and thanks to Dr. D. B. Shinde, Professor

& Head, Department of Chemical Technology, who allowed me to use all the

facilities of the department and for arranging Industrial visit at M/s Wockhardt

Biotech Limited, Aurangabad. He also supported me like a pillar for constant

inspiration.

It is a great pleasure and moment of satisfaction for me to express deepsense of gratitude towards Dr. P. S. Wakte, Reader, Department of Chemical

Technology, and my project guide for his continuous encouragement and

guidance in making my project successful.

My sincere thanks to Mr. Vinay Lomte, Associate Professor,

Department of Chemical Technology for guidance and arranging Industrial visit

at M/s Wockhardt Biotech Limited, Aurangabad.

I would like to express my heart-felt thanks to my colleagues Mr. A. L.

Kharat, Mr. C. R. Gadekar, Mr. M. D. Deoraye and my Senior Mr. R. R.

Ratha, Mr. S. P. Deshmukh for their assistance, criticisms, useful insights,

encouragement and compassion. I gratefully acknowledge M/s Wockhardt

Limited, Aurangabadfor giving permission to visit different Departments in the

premises.

Finally, this thesis would not have been possible without the confidence,

endurance and support of my family. My family has always been a source of

inspiration and encouragement. I wish to thank my parents, Shri M. R. Mohato

and Smt. R. Devi, whose love, teachings and support have brought me this far.

DULAL M. MOHATO


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CONTENTS

Sr. No Name of chapter Page No.

1.

Introduction

Tablet 4 Selected Pharmacotherapy Division 9 Selected drugs for manufacturing 12 Drug information 12 Commercial and Pharmaceutical Importance 21

2. Objectives 253. Market Survey 264. Technology Development

Manufacturing formula 42 List of raw materials 51 List of equipments and machinery 52 Suppliers of raw materials 53

5. Technical Aspects Plant location 58 Building and facilities 60 Various departments 67 Layout design 82

6. Economic Aspects 1157. Conclusion 1318. References 132


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My M.tech (Chemical) Drugs&Pharmaceutical Certficates