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Mutations and Autosomal Dominant Disorders Genetic Mistakes

Mutations Autosomal Dominant

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Mutations and Autosomal Dominant Heredity

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Page 1: Mutations Autosomal Dominant

Mutations and Autosomal DominantDisorders

Genetic Mistakes

Page 2: Mutations Autosomal Dominant

Mutations

Mutation – a change in the DNA message

Mutations cause the wrong protein to be made (they may no longer be functional)

Page 3: Mutations Autosomal Dominant

3 Types of Mutations

Deletion – section of DNA removed

Insertion – section added

Substitution – bases switched

Page 4: Mutations Autosomal Dominant

Causes of Mutations

Errors in replication or transcription

Powerful radiation: x-rays, UV light, etc.

Page 5: Mutations Autosomal Dominant

Genetic Diseases

Can be caused by mutations or by additional/fewer chromosomes

CCMs are an autosomal dominant genetic disorder.

Page 6: Mutations Autosomal Dominant

Autosomal Dominant Disorders

The mutated gene is dominant and presents in one parent.

The children have a 50% chance of being affected.


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