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Multi-effect Pharmastills
MainfeaturesTheprinciplefeaturesofthestilmasMulti-effectpharmastillsare:• TheWFIisproducedafteronlyfewminutesfromswitchon.• Condenser/evaporatorandheatrecoverysystemisthebestperformanceintermsofenergysaving.• Withoutanyplantmodificationcanweproducewithavariationofcapacityto80%.• Theuniquepurificationsystemistheprincipleforguaranteeofdistilatepurity.• Extremelylimitedmaintenanceandlogliveduethesimpleandcleanmechanicalconstruction.• LowwastageasblowdownandDegassingtakenfromthelastcolumnisthemostefficientmethod.
OperatingprincipleTheMS-HPSisbasedonthe“ThinFallingFilm”andMultistageprinciplesingeniouslycombined.
Endotoxinreduction
AspecialdesignofthedecontaminationchamberallowsSTILMAStograntthehighestperformancesintermsofendotoxinscontentreduction.Thegravitationalseparationsystemhasproventobeextremelysimpleandeffective.Increasingendotoxinlevelsinthefeedwaterhasproventhecapabilitytoreduceendotoxinlevelbylog6.(1,000,000times)
Pharmastilleffectdesign
Eacheffectconsistsofademountabletubeheatexchangerontop,feedingpressurized,evaporatedfeedwatertoaseparationchamberbelow.Puredrysteamrisestotheoutletatthetopofthischamber;entrainedimpuritiesfallbacktothebottom,feedwaterforthenextcolumnandultimately,rejectblowdown.Aflangedconnectionallowsthecolumnsectionstoexpandwithoutrestraint. Contact
Steritec BelgiumAv.J.Wybran45 BBE-1070 BrusselsT+32(0)252011 50E [email protected]
Steritec TheNederlandsVanNelleweg6060*NL-3044BCRotterdamPostbox13060*NL-3004HBRotterdamT+31 (0)10 753 72 21E [email protected]
ConstructionTheplantiscompletelymadeinAISI316Lstainlesssteel,thefinishingoftheactivesurfacesarepickledandpassivatedandmirrororelectropolishing(to0,6µR)canbemadeonrequest.Product(WFI)contactpartsaremechanicallypolishedandpipingisorbitallywelded.Forthebestpossibleinspection,thedecontaminationchamberistotallyempty.Theabsenceinthisareaofweldingdramaticallyreducetheriskofcorrosion,foraverylongexpectedlife.Pre-heatersandexchangerareoftheshellandtubetype.Thegeneralconstructiondesign,coupledwiththedescribeddecontaminationprocess,ensureaveryhighflexibilityinequipmentlayout.
StilmasindustrialcompanyhasengineeredtheMultieffectpharmastillsthatproducesdistilledWaterforInjectionthatmeetsthelatestrequirementsoftheinternationalPharmacopeiasincludingUSP,EPandJP.Thepharmastillmodularconstructionoffersawidechoiceofconfigurationsallowingoptimumpaybacktimes.Standardmodelsrangeisfrom60to20.000lts/houtput.
THE SPECIALISTS IN STERILIZATION TECHNOLOGIES
Pharmastills Multi-effect Technology
MS-HPSThePharmastillmodularconstructionoffersawiderangeofconfigurationsallowingoptimumpaybacktimes.Standardmodelsrangefrom60to22.000lts/houtput.
MS-HPSThePharmastillMS-EhasbeendesignedbyStilmasforapplicationsincaseindustrialsteamisnotavailable.
MSCOMBITheinnovativePharmastillMS– CombiintegratesintoonesystemthepossibilityofsimultaneousandindependentproductionofWFIandpuresteamindifferentcapacitiesandratios.
PharmastillMSCOMBIisabletosimultaneouslygeneratePureSteamandWaterforinjectionatdifferentratesandcapacity.
