Monday, March 5, 2012Put your Extra Credit in bin on front desk

Multiple Choice (13/18 or less)

AND

Short Answer Retakes

Must be done in tutorial today and tomorrow

No homework

Protein Structure CheckupVersion A: #10

Version B: #5

Choose answer A or B for that question.

• Make an entry-

Entry 16- Protein Networks-3/5/12

Metabolic Networks Introduction

Network ReviewNetwork

an interconnected or interrelated chain, group, or system.

Nodesmembers of the network

Edgesthe relationships between the nodes

Food Network

Lactase Lab

• Lactose is composed of Galactose and Glucose

• Lactase breaks lactose into…

Lactose

Lactase

How can we represent this with nodes and edges?

Lactose

Glucose

Lactase

Galactose

Metabolic Network

Glycogen

UDP-Glucose

Lactase

Galactose

Galactose P

UDP-GalactoseGlucose-1-P

Glucose-6-PGlucose

ATPADP

Key Terms• Metabolism: all the chemical

reactions occurring within a cell or a whole organism

• Metabolite: any molecule produced by chemical reactions of metabolism

A metabolic pathway is a series of enzyme reactions connecting one metabolite to another–Like a single food chain within a food

web

Click here for animation of metabolic pathway

Metabolic Network

A B C D

E F

Metabolic Network

A B C D

E F

X

Metabolic Network

CBA X

E F

D

Result:

-Accumulation of B

-Decrease of C, D, E, and F

“Coat Color in Labrador Retrievers”

Cocoa Midnight

Guiding Question:

“How does variation exist between organisms?”

Read: “Coat Colors in Labrador Retrievers” to help you answer this question.

Vocab to know for reading.• Pigment = A substance, such as chlorophyll or

melanin, that produces a characteristic color in plant or animal tissue.

• Skin and Hair pigments are produced in cells called melanocytes.

• Synthesize = to put together.

Labrador (dog) pigmentation

Tyrosine Dopaquinone

Brown pigment

Black pigment

Yellow pigmenttyrosinase

TRP-2

TRP-1

What color is the dog’s coat?

  

Black

Tyrosine Dopaquinone

Brown pigment

Black pigment

Yellow pigmenttyrosinase

TRP-2

TRP-1

What would happen if the enzyme TRP – 1 was missing?

Black pigment

What color is the dog’s coat? Brown

Tyrosine Dopaquinone

Brown pigment

Black pigment

Yellow pigmenttyrosinase

TRP-2

TRP-1

So what would happen if the enzymes TRP – 1 and TRP-2 were

both missing?

Black pigment

What color is the dog’s coat? Yellow

Brown pigment