International Journal of Molecular Happiness 2011 ©

SEMISOLID ALTERNATIVE FORMULATION FOR MOJITO ADMINISTRATION

J.D.G. Mantillaa,c, F.A. Ramirezb,c , A. Meleroa,d,**

(a) Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, Campus A4.1,

D-66123 Saarbruecken, Germany

(b) Max Planck Institute for Informatics, Campus E1.4, 66123 Saarbrücken, Germany

(c) Montag Pola Institute for Latin American Studies and Ethics, Campus-Mensa Saarbrücken, Germany

(d) Spanish Therapy Group in Cultural Affairs and Spainology, Campus-Mensa Saarbrücken, Germany

**Corresponding Author

KEYWORDS: Mojito, iced water, Ethanol, antidepressive, solid-state drink

INTRODUCTION: Mojito(MJ) is an Et-OH H2O mixture commounly ingested in tropical countries

of the western hemispheres as a happiness enhancer, dancing coadjuvant, social binder and

antidepressive (Yankee 2004, Orishas 2005, Lopez and Combo 2000 and Ñato 2009). Some authors

have also reported foreign language skills improvements upon small doses of MJ, although the effect

dramatically declines if the recommended threshold dose is overpassed (Biling 2011). MJ is normally

delivered in a fluid state at low temperatures with crystallized water at nocturnal hours. The development

of MJ has stagnated during the past decades although new methods to improve its delivery hours,

transportation and stability are nowadays available. In this work we present an innovative Ice-Free

Semisolid-State Mojito (IF-SSMJ) that has several technical advantages compared to traditional MJ.

MATERIALS AND METHODS All reagents and biologicals were purchased from Bio-Cora,

Symply-gen, Rewe-Pharm, Netto-Lab, Lidl-Tech and Aldi-Synthesis, except Clinopodium douglasii

sp, that was kindly provided by a local distributor. All chemicals were of highest available quality and

were used as received. IF-Semisolid-State Mojito was made as previously reported (Some Guys 2007

and Some Others 2008) with minor modifications in excipients, temperatures and equipment that we

prefer not to mention in detail to avoid replication.

EXPERIMENTAL DESIGN: Spontaneous planning, alcoholic driven, cylindrical factorial design

with slice optimization. Regular statistical tools like statistical pan, statistical spoons and statistical mixer.

IF-SSMJ was prepared by nano-baking methods, and freeze-thaw procedures as reported by

(Agentcoxt al. 2007). IF-SSMJ was stored at a temperature between 2-8°C until conduction of the

characterization experiments. Organoleptic properties of IF-SSMJ were evaluated by double-blind

clinical studies among 50 healthy individuals, male and female, of ages varying between 22 and 65 years

Published On line: 11 October 2011

International Journal of Molecular Happiness 2011 ©

and disparate nationalities among all over the globe, following the method described by (Arguiñano

2011). These studies led to slight changes in the original composition until a final improved formulation

could be released for human consume (Cruz et al. 1968)

RESULTS IF-Solid-state mojito overcame traditional mojito in all the observed variables (table 1)

Table 1 Response Variable for the two evaluated preparations.

Variable MJ IF-SSMJ

Stability at room temperature 20 mins 7200 mins

Stability at 4`C 120 mins 20000 mins

Energy store capacity (Kcal/g) More than expected even more

Hours of consumption 20:30-5:00 09:30-5:00 *

Units produced per batch 1 32 or more **

Possibility of transportation No Yes

Antidepresive Effect ++ ++++ ***

Social Binder function 4.8 8.6 ****

*Can be served at day and night

** Typical human dose

*** Measured in J.D. Degrees

**** Log-normalized-data representing a broader spectrum (non nocturnal subjects) of individuals

DISCUSSION: In the kitchen, NOW! HURRY UP! Yummy!!!

CONCLUSION: we have developed a revolutionary form of MJ, Highlly homogeneous, with

incredible stability that can be prepared without crystallized water that uses to be very expensive

(Specially in Germany) and hard to transport. IF-SSMJ can be administered alone or in combination

with fluid MJ to increase the desired effects. This oral solid form can be consumed at every time of the

day, even at higher concentrations of Et-OH, what can have a big impact in public health and happiness.

SUPPORTING DATA: .jpeg and .wmv files will be available for download after monday using

facebook© technology.

Published On line: 11 October 2011

International Journal of Molecular Happiness 2011 ©

ACKNOWLEDGMENTS: To DAAD for Financial support of this project. To Ernest Hemingway

for transforming a girly drink in a Tough guys drink and for giving MJ its deserved place in Universal

Literature.

ADDITIONAL DECLARATIONS: IF-SSMJ is not recommended for subjects under 216 months

of age or for subjects with pregnancy symptoms (Specially female). Dancing skills self-perception could

be highly altered and modified by the consumption of MJ in the fluid or solid state. (Reggpok et al. 2008

and Papichulo 2007). In some cases (frequency>15%) , significant deformations in perception of the

reality, followed by an unusual lost of shyness has been observed (data prudently not shown),

confirming the tendency reported by ( Aranxxxa 2007).

NOTE: Edulcorated semi-solid formulation of animal proteins and carbohydrates is also available for

volunteers whose personal convictions, emotional status or adverse reactions discourage alcohol

consumption.

Published On line: 11 October 2011