Moderator : Opening - Intensive · Lars Wiuff Andersen (Aarhus, Denmark) 17:15 - 17:25 - Discussion ... Massimo Antonelli (Rome, Italy) 12:00 - 12:15 - Discussion . Tuesday 19 March

Tuesday 19 March 2019 - AM ROOM : HLB Room Opening [Standard presentation] Moderator : Jacques Creteur (Brussels , Belgium) Moderator : John J Marini (St Paul, United States)

8:30 - 8:50 - Welcome: emergency and critical care medicine Jean-Louis Vincent (Brussels , Belgium)

8:55 - 9:15 - Report of the Round Table conference on ‘Before the ICU‘

Maaret Castren (Helsinki, Finland), Laurie Morrison (Toronto , Canada)

9:20 - 9:40 - TBA

9:45 - 10:05 - The Max Harry Weil Memorial lecture: new developments in CPR Jerry Nolan (Bath, United Kingdom)

10:10 - 10:30 - Critical care medicine in space

Matthieu Komorowski (London, United Kingdom)

Oxygen: too much of a good thing? [Standard presentation] Moderator : Karin Amrein (Graz , Austria) Moderator : Beatrice Beck-Schimmer (Zurich, Switzerland)

11:00 - 11:15 - How can it be toxic? Laveena Munshi (Toronto, Canada)

11:15 - 11:30 - Hypoxemia or hyperoxia: which is worse? Thomas Scheeren (Groningen, Netherlands)

11:30 - 11:45 - Hyperoxia during circulatory shock: the type of shock matters

Peter Radermacher (Ulm , Germany)

11:45 - 12:00 - Is hyperoxia really bad for the brain after cardiac arrest? Fabio S. Taccone (Brussels , Belgium)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - AM ROOM : Gold Hall Managing ARDS [Standard presentation] Moderator : Robert M Kacmarek (Boston, United States) Moderator : Xavier Monnet (Le Kremlin-Bicêtre , France)

11:00 - 11:15 - Fluid management Greg Martin (Atlanta, United States)

11:15 - 11:30 - Ventilatory support guided by mechanics

Laurent Brochard (Toronto, Canada)

11:30 - 11:45 - Hypercapnia in ARDS: accept, remove or induce? John G Laffey (Galway, Ireland)

11:45 - 12:00 - Rescue therapies

Carolyn S Calfee (San Francisco , United States)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - PM ROOM : Gold Hall CPR [Standard presentation] Moderator : Markus Skrifvars (Helsinki, Finland) Moderator : Alain Cariou (Paris, France)

13:45 - 14:00 - How lab studies can help Theresa Mariero Olasveengen (Oslo, Norway)

14:00 - 14:15 - Is there any age limit?

David Grimaldi (Brussels, Belgium)

14:15 - 14:30 - Sudden cardiac death in athletes Laurie Morrison (Toronto , Canada)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Asystolic and PEA patients are not the same

Hans Friberg (Lund , Sweden)

15:00 - 15:15 - Airway management Jerry Nolan (Bath, United Kingdom)

15:15 - 15:30 - Gas exchange Jean-Christophe Richard (Annecy, France)

15:30 - 15:45 - Discussion

15:45 - 16:00 - Ventilation

Theresa Mariero Olasveengen (Oslo, Norway)

16:00 - 16:15 - Which drugs, when, and why? Michael W Donnino (Boston, United States)

16:15 - 16:30 - Which patient, when and where to transport after out–of–hospital cardiac arrest


16:30 - 16:45 - Discussion

16:45 - 17:00 - Have we really made progress? Jan Bakker (New York, United States)

17:00 - 17:15 - Future therapies

Lars Wiuff Andersen (Aarhus, Denmark)

17:15 - 17:25 - Discussion

We need central venous pressure. [Pro-con debate] Moderator : Denise Veelo (Amsterdam , Netherlands)

17:30 - 18:00 - We need central venous pressure. CON Rinaldo Bellomo (Melbourne, Australia)

PRO Antonio Pesenti (Milan , Italy)

Tuesday 19 March 2019 - AM ROOM : Copper Hall The SOSD phases of fluid management [Standard presentation] Moderator : Alexander Zarbock (Münster, Germany) Moderator : Fabio Guarracino (Pisa, Italy)

11:00 - 11:15 - Salvage Marc Maegele (Cologne , Germany)

11:15 - 11:30 - Optimization

Olivier Huet (Brest, France)

11:30 - 11:45 - Stabilization Greg Martin (Atlanta, United States)

11:45 - 12:00 - Deescalation

Jacques Creteur (Brussels , Belgium)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - PM ROOM : Copper Hall Preparing for the next catastrophe [Standard presentation] Moderator : Karim Brohi (London , United Kingdom) Moderator : Marc Maegele (Cologne , Germany)

13:45 - 14:00 - How a military hospital manages a mass casualty event Michael Reade (Brisbane, Australia)

14:00 - 14:15 - How a civilian hospital manages a mass casualty event

Carole Ichai (Nice, France)

14:15 - 14:30 - How can simulation exercises help Raed Arafat (Bucarst, Romania)

14:30 - 14:40 - Discussion

14:40 - 14:55 - Emergency medical provision at the Olympics

David Zideman (Pinner, United Kingdom)

14:55 - 15:10 - The Melbourne thunderstorm asthma disaster Rinaldo Bellomo (Melbourne, Australia)

15:10 - 15:25 - Acute traumatic coagulopathy due to warfare

Beverley Hunt (London , United Kingdom)

15:25 - 15:40 - Mass media and fake news Raed Arafat (Bucarst, Romania)

15:40 - 15:55 - Discussion

15:55 - 16:10 - Break

Cellular alterations [Standard presentation] Moderator : Zudin Puthucheary (London, United Kingdom) Moderator : Arthur van Zanten (Ede, Netherlands)

16:10 - 16:25 - What dictates cell behavior / How cells decide to activate or to die John C Marshall (Toronto , Canada)

16:25 - 16:40 - The role of coagulopathy

Jawed Fareed (Maywood, United States)

16:40 - 16:55 - The host immune response to septic and non–septic shock. Tom van der Poll (Amsterdam , Netherlands)

16:55 - 17:05 - Discussion

17:05 - 17:20 - Response to endotoxin: from immunostimulation to immunosuppression

Ricard Ferrer (Barcelona, Spain)

17:20 - 17:35 - The effects of endotoxin on the bone marrow Peter Pickkers (Nijmegen, Netherlands)

17:35 - 17:50 - Immune pattern recognition

Brice Gaudillière (Stanford, United States)

17:50 - 18:00 - Discussion

Tuesday 19 March 2019 - AM ROOM : Salle M (Bozar) Preventing infection [Standard presentation] Moderator : Michael Pulia (Madison, United States) Moderator : Kristina Rudd (Pittsburgh, United States)

11:00 - 11:15 - Any place for chlorhexidine washes? Rinaldo Bellomo (Melbourne, Australia)

11:15 - 11:30 - Vaccination strategies

Tobias Welte (Hannover , Germany)

11:30 - 11:45 - Is SDD dead? A realistic update Jeroen Schouten (Nijmegen, Netherlands)

11:45 - 12:00 - The microbiome of the ICU environment

John C Marshall (Toronto , Canada)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - PM ROOM : Salle M (Bozar) Analgo-sedation [Standard presentation] Moderator : Michelle N Gong (New York, United States) Moderator : E Wesley Ely (Nashville, United States)

13:30 - 13:45 - What we´ve learned from sport medicine David Zideman (Pinner, United Kingdom)

13:45 - 14:00 - Pain management after burns

Tina Palmieri (Sacramento, United States)

14:00 - 14:15 - Is critical care contributing to the opioid epidemic? Hannah Wunsch (Toronto, Canada)

14:15 - 14:25 - Discussion

14:25 - 14:40 - Propofol infusion syndrome: a neglected problem?

Geert Meyfroidt (Leuven , Belgium)

14:40 - 14:55 - Is clonidine just as good as dexmedetomidine? Michael Reade (Brisbane, Australia)

14:55 - 15:10 - The immunomodulatory properties of alpha-2 agonists

Timothy Walsh (Edinburgh , United Kingdom)

15:10 - 15:25 - Discussion

15:25 - 15:40 - Co–administration of ketamine with dexmedetomidine Yahya Shehabi (Melbourne, Australia)

15:40 - 15:55 - Inhaled ICU sedation may protect the lungs

Matthieu Jabaudon (Clermont-Ferrand, France)

15:55 - 16:10 - Inhaled ICU sedation may protect the other organs Beatrice Beck-Schimmer (Zurich, Switzerland)

16:10 - 16:25 - Discussion

16:25 - 16:40 - Early goal-directed sedation: a spicy topic

Yahya Shehabi (Melbourne, Australia)

16:40 - 16:55 - How to monitor ICU sedation Ulf Günther (Oldenburg, Germany)

16:55 - 17:10 - No sedation: it works

Andreas Faltlhauser (Weiden in der Oberpfalz, Germany)

17:10 - 17:25 - Discussion

Inhaled antibiotics in the ICU [Pro-con debate] Moderator : Jan De Waele (Ghent , Belgium)

17:30 - 17:40 - Yes, in some cases Gianluigi Li Bassi (Barcelona, Spain)

17:40 - 17:50 - No, they do not work


17:50 - 18:00 - Discussion

Tuesday 19 March 2019 - AM ROOM : Tent The best i.v. fluid [Standard presentation] Moderator : Matthieu Jabaudon (Clermont-Ferrand, France) Moderator : Nicole Juffermans (Amsterdam , Netherlands)

11:00 - 11:15 - Hyperchloremia is associated with poor outcomes Hector R Wong (Cincinnati , United States)

11:15 - 11:30 - How is hyperchloremia bad for the kidneys?

John Prowle (London, United Kingdom)

11:30 - 11:45 - Start with the optimal i.v. fluid Wesley Self (Nashville, United States)

11:45 - 12:00 - There will never be an ideal i.v. fluid

Jean-Louis Vincent (Brussels , Belgium)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - PM ROOM : Tent Corticosteroids in sepsis: for which patients? [Standard presentation] Moderator : B Taylor Thompson (Boston , United States) Moderator : Antoni Torres (Barcelona , Spain)

13:45 - 14:00 - Who is at risk of relative adrenal insufficiency? Greet Van den Berghe (Leuven , Belgium)

14:00 - 14:15 - Just the sickest?

Djillali Annane (Garches , France)

14:15 - 14:30 - Anybody? Rinaldo Bellomo (Melbourne, Australia)

14:30 - 14:45 - Discussion

14:45 - 15:00 - We need biomarkers

Hector R Wong (Cincinnati , United States)

15:00 - 15:15 - It’s all about the right dose, right time & right duration Stephen M Pastores (New York, United States)

15:15 - 15:30 - Discussion

15:30 - 15:45 - Break

In the ambulance [Standard presentation] Moderator : Christopher Seymour (Pittsburgh, United States) Moderator : John Welch (London , United Kingdom)

15:45 - 16:00 - Medical emergencies during sports events David Zideman (Pinner, United Kingdom)

16:00 - 16:15 - Rapid risk identification

Maaret Castren (Helsinki, Finland)

16:15 - 16:30 - Do we need a doctor in the ambulance? Marc Sabbe (Leuven , Belgium)

16:30 - 16:45 - Improving emergency medical dispatch

Theresa Mariero Olasveengen (Oslo, Norway)

16:45 - 17:00 - Discussion

17:00 - 17:15 - Inter–hospital transports on ECMO Lars Broman (Stockholm, Sweden)

17:15 - 17:30 - Prehospital plasma administration

Jacques Duranteau (Le Kremlin-Bicêtre , France)

17:30 - 17:45 - Prehospital antibiotic administration Michael Reade (Brisbane, Australia)

17:45 - 18:00 - Discussion

Tuesday 19 March 2019 - AM ROOM : Silver Hall The microbiome in critical Illness [Standard presentation] Moderator : Paolo Angeli (Padua, Italy) Moderator : Thomas Lescot (Paris, France)

11:00 - 11:15 - Why do so few microorganisms cause disease? John C Marshall (Toronto , Canada)

11:15 - 11:30 - It can mirror those of the dead

Paul Wischmeyer (Durham, United States)

11:30 - 11:45 - Therapeutic implications Antoni Torres (Barcelona , Spain)

11:45 - 12:00 - Does the respiratory microbiome predict VAP onset?

Massimo Antonelli (Rome, Italy)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - PM ROOM : Silver Hall After EOLIA [Standard presentation] Moderator : Marco V Ranieri (Bologna, Italy) Moderator : Lars Broman (Stockholm, Sweden)

13:45 - 14:00 - I´ll have another look at our study Alain Combes (Paris , France)

14:00 - 14:15 - It was the most positive negative trial in intensive care

Daniel Brodie (New York, United States)

14:15 - 14:30 - Will it change our practice? Niall Ferguson (Toronto , Canada)

14:30 - 14:45 - Discussion

14:45 - 15:00 - We use ECMO too liberally in some patients

Michael Quintel (Göttingen , Germany)

15:00 - 15:15 - Do we need another trial? Antonio Pesenti (Milan , Italy)

15:15 - 15:30 - Discussion

15:30 - 15:45 - Break

Evaluating volemic status [Standard presentation] Moderator : John Prowle (London, United Kingdom) Moderator : Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

15:45 - 16:00 - What´s new in 2019? Xavier Monnet (Le Kremlin-Bicêtre , France)

16:00 - 16:15 - Urine analysis can detect hypovolemia

Robert G Hahn (Södertälje, Sweden)

16:15 - 16:30 - Volemic status matters only when the microcirculation is altered Can Ince (Amsterdam , Netherlands)

16:30 - 16:45 - How ultrasound techniques can help

Michel Slama (Amiens , France)

16:45 - 17:00 - Discussion

17:00 - 17:15 - Is vena cava evaluation reliable? Antoine Vieillard-Baron (Boulogne-Billancourt , France)

17:15 - 17:30 - I have a new method

Frédéric Michard (Lausanne, Switzerland)

17:30 - 17:45 - My patient is fluid responsive, but I may not give fluid Paul H Mayo (New Hyde Park, United States)

17:45 - 18:00 - Discussion

Tuesday 19 March 2019 - AM ROOM : 100 Hall Early antibiotic therapy: how early? [Standard presentation] Moderator : Jean-Louis Teboul (Le Kremlin-Bicêtre, France) Moderator : Benjamin Tang (Sydney, Australia)

11:00 - 11:15 - Early antibiotics: benefits and harms Vincent Liu (Oakland, United States)

11:15 - 11:30 - Early antibiotics save lives

Christopher Seymour (Pittsburgh, United States)

11:30 - 11:45 - ... do they? Mervyn Singer (London, United Kingdom)

11:45 - 12:00 - Watchful waiting?

Jan De Waele (Ghent , Belgium)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - PM ROOM : 100 Hall Early resuscitation in sepsis [Standard presentation] Moderator : Maurizio Cecconi (Rozzano, MI, Italy) Moderator : Vincent Liu (Oakland, United States)

13:30 - 13:45 - Blood culture results do not influence outcome Christopher Seymour (Pittsburgh, United States)

13:45 - 14:00 - Source control in sepsis


14:00 - 14:15 - How early is early? Steven Simpson (Kansas City, United States)

14:15 - 14:30 - Discussion

14:30 - 14:45 - How much oxygen?

Wesley Self (Nashville, United States)

14:45 - 15:00 - Timing of intubation Jean-Damien Ricard (Colombes, France)

15:00 - 15:15 - MAP of 65 mmHg for everyone?

Peter Radermacher (Ulm , Germany)

15:15 - 15:30 - Discussion

15:30 - 15:45 - Is low diastolic blood pressure a real problem? Jan Bakker (New York, United States)

15:45 - 16:00 - Non–invasive assessment of cardiac output can help

Steven Simpson (Kansas City, United States)

16:00 - 16:15 - Cardiac dysfunction assessment in septic shock patients Michel Slama (Amiens , France)

16:15 - 16:30 - From EGDT to late(r) ScvO2 checks


16:30 - 16:45 - Discussion

16:45 - 17:00 - Break

Organ donation [Standard presentation] Moderator : Marlies Ostermann (London , United Kingdom) Moderator : Pierre-François Laterre (Brussels , Belgium)

17:00 - 17:15 - Brain death 50–years after the Harvard report Giuseppe Citerio (Monza, Italy)

17:15 - 17:30 - Brain death: beware of apneic locked–in syndrome

Steven Laureys (Liège , Belgium)

17:30 - 17:45 - DCD: can we also take the heart? Jacques Creteur (Brussels , Belgium)

17:45 - 18:00 - Discussion

Tuesday 19 March 2019 - AM ROOM : Terarken (Bozar) When (not) to prone [Standard presentation] Moderator : Samir Jaber (Montpellier, France) Moderator : John P Kress (Chicago, United States)

11:00 - 11:15 - Hemodynamic effects Antoine Vieillard-Baron (Boulogne-Billancourt , France)

11:15 - 11:30 - We could target intraabdominal pressure

Brian Kavanagh (Toronto, Canada)

11:30 - 11:45 - Prone vs. ECMO: prone still wins Daniel Brodie (New York, United States)

11:45 - 12:00 - Moderate to severe ARDS: first prone then ECCO2R

Alain Combes (Paris , France)

12:00 - 12:15 - When not to prone Stephane Gaudry (Colombes, France)

12:15 - 12:30 - Discussion

Tuesday 19 March 2019 - PM ROOM : Terarken (Bozar) Nutritional support [Standard presentation] Moderator : Heleen Oudemans-Van Straaten (Amsterdam , Netherlands) Moderator : Jean-Charles Preiser (Brussels , Belgium)

13:45 - 14:00 - When can you safely start feeding Juan B. Ochoa (Danville, United States)

14:00 - 14:15 - ESPEN guidelines

Pierre Singer (Petah Tikva , Israel)

14:15 - 14:30 - New tools to assess nutritional status in the ICU Paul Wischmeyer (Durham, United States)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Malabsorption during critical illness

Marianne Chapman (Adelaide , Australia)

15:00 - 15:15 - How we could better achieve our goals Stephan Jakob (Bern, Switzerland)

15:15 - 15:30 - Choosing wisely as applied to medical nutrition

Mette M Berger (Lausanne , Switzerland)

15:30 - 15:45 - Discussion

15:45 - 16:00 - Break

Cardiac problems [Standard presentation] Moderator : Sven-Erik Ricksten (Gothenburg, Sweden) Moderator : Daniel De Backer (Brussels, Belgium)

16:00 - 16:15 - Initial management of severe heart failure Fabio Guarracino (Pisa, Italy)

16:15 - 16:30 - update on inotropic agents


16:30 - 16:45 - Takotsubo cardiomyopathy Anthony McLean (Sydney , Australia)

16:45 - 17:00 - Peripartum cardiomyopathy


17:00 - 17:15 - Discussion

Tuesday 19 March 2019 - AM ROOM : 400 Hall Glucose control [Standard presentation] Moderator : Juan B. Ochoa (Danville, United States) Moderator : Greet Van den Berghe (Leuven , Belgium)

11:00 - 11:15 - A real world experience Grant Bochicchio (St Louis, United States)

11:15 - 11:30 - Glucose metabolism in immune cells during sepsis

Tom van der Poll (Amsterdam , Netherlands)

11:30 - 11:45 - Glucose management in diabetes Rinaldo Bellomo (Melbourne, Australia)

11:45 - 12:00 - Glucose variability: caused by nutrition variability?


12:00 - 12:15 - Adaptive and personalized glycemic control Jean-Charles Preiser (Brussels , Belgium)

12:15 - 12:30 - Discussion

Tuesday 19 March 2019 - PM ROOM : 400 Hall Acid-base – Electrolytes [Standard presentation] Moderator : Pietro Caironi (Turin, Italy) Moderator : Jeremy Beitler (New York, United States)

13:30 - 13:45 - Should we use bicarbonate for metabolic acidosis? Samir Jaber (Montpellier, France)

13:45 - 14:00 - Should we use bicarbonate for respiratory acidosis?


14:00 - 14:15 - Transurethral resection syndrome: a rare but feared complication Robert G Hahn (Södertälje, Sweden)

14:15 - 14:25 - Discussion

14:25 - 14:40 - Managing hyponatremia in edematous patients

Paolo Angeli (Padua, Italy)

14:40 - 14:55 - Preventing overcorrection in severe hyponatremia Stephane Gaudry (Colombes, France)

14:55 - 15:10 - Hypophosphatemia

Thomas Lescot (Paris, France)

15:10 - 15:20 - Discussion

15:20 - 15:35 - Break

The ICU is full... [Standard presentation] Moderator : Massimo Antonelli (Rome, Italy) Moderator : John J Marini (St Paul, United States)

15:35 - 15:50 - Demand and strain on the ICU Elizabeth Wilcox (Toronto, Canada)

15:50 - 16:05 - Ethics of allocating ICU resources


16:05 - 16:20 - High flow nasal oxygen: safe outside the ICU? Antonio Pesenti (Milan , Italy)

16:20 - 16:30 - Discussion

How to report data [Standard presentation] Moderator : Jerrold H Levy (Durham, United States) Moderator : Emma Grainger (Oxford, , United Kingdom)

16:30 - 16:45 - How to perform a systematic review Lars Wiuff Andersen (Aarhus, Denmark)

16:45 - 17:00 - How to present a poster

Karin Amrein (Graz , Austria)

17:00 - 17:15 - Editing and publishing Elie Azoulay (Paris , France)

17:15 - 17:25 - Discussion

ICU delirium [Tutorial]

17:30 - 18:00 - ICU delirium Ulf Günther (Oldenburg, Germany)

Tuesday 19 March 2019 - AM ROOM : Panoramic Hall ECPR: yes or no? [Standard presentation] Moderator : David Zideman (Pinner, United Kingdom) Moderator : Michael W Donnino (Boston, United States)

11:00 - 11:15 - ECPR: what is the evidence? Lars Wiuff Andersen (Aarhus, Denmark)

11:15 - 11:30 - ECPR: a lot of hype

Laurie Morrison (Toronto , Canada)

11:30 - 11:45 - When to stop is getting harder to decide Theresa Mariero Olasveengen (Oslo, Norway)

12:00 - 12:15 - Discussion

Tuesday 19 March 2019 - PM ROOM : Panoramic Hall Traumatic brain injury (T) [Tutorial]

13:30 - 14:00 - Traumatic brain injury Jacques Duranteau (Le Kremlin-Bicêtre , France)

Patient-ventilator dyssynchrony [Tutorial]

14:05 - 14:35 - Patient–ventilator dyssynchrony Dean R Hess (Danvers, United States)

The oliguric patient [Tutorial]

14:40 - 15:10 - The oliguric patient Michael Joannidis (Innsbruck , Austria)

Pediatric emergencies [Tutorial]

15:15 - 15:45 - Pediatric emergencies Karen Choong (Hamilton, Canada)

PEEP titration in ARDS [Tutorial]

15:50 - 16:20 - PEEP titration in ARDS Diederik Gommers (Rotterdam, Netherlands)

Catheter-related infections [Tutorial]

16:25 - 16:55 - Catheter–related infections Jean-François Timsit (Paris, France)

Hyponatremia [Tutorial]

17:00 - 17:30 - Hyponatremia Pietro Caironi (Turin, Italy)

How to manage refractory hypoxemia [Tutorial]

17:35 - 18:00 - How to manage refractory hypoxemia Niall Ferguson (Toronto , Canada)

Tuesday 19 March 2019 - AM ROOM : Studio Room How to make the brain happier [Standard presentation] Moderator : Jacques Duranteau (Le Kremlin-Bicêtre , France) Moderator : Yahya Shehabi (Melbourne, Australia)

11:00 - 11:15 - Keep the sugar low Geert Meyfroidt (Leuven , Belgium)

11:15 - 11:30 - Optimize sodium levels

Stephan Jakob (Bern, Switzerland)

11:30 - 11:45 - Optimize mechanical ventilation Victoria McCredie (Toronto, Canada)

11:45 - 12:00 - Be careful during RRT

Detlef Kindgen-Milles (Düsseldorf , Germany)

12:00 - 12:15 - Induce hypertension in some cases Frank van Haren (Canberra, Australia)

12:15 - 12:30 - Discussion

Tuesday 19 March 2019 - PM ROOM : Studio Room Right heart function [Standard presentation] Moderator : Edward Litton (Perth, Australia) Moderator : Elias N Baedorf Kassis (Boston, United States)

13:30 - 13:45 - How to define right heart failure Antoine Vieillard-Baron (Boulogne-Billancourt , France)

13:45 - 14:00 - Right ventricular function assessment by echo is not very accurate in the critically ill

Anthony McLean (Sydney , Australia)

14:00 - 14:15 - Ventriculo–arterial coupling and outcome from pulmonary hypertension Michael R. Pinsky (Pittsburgh, United States)

14:15 - 14:30 - Discussion

14:30 - 14:45 - The complex effects of high PEEP


14:45 - 15:00 - Pharmacological manipulation of pulmonary hypertension in the ICU Harm Jan Bogaard (Amsterdam, Netherlands)

15:00 - 15:15 - Diagnosing pulmonary embolism in the ICU

John Simpson (Newcastle upon Tyne, United Kingdom)

15:15 - 15:30 - Life–threatening pulmonary embolism: no thrombectomy, just ECMO Alain Combes (Paris , France)

15:30 - 15:45 - Discussion

15:45 - 16:00 - Break

Severe viral diseases [Standard presentation] Moderator : Mervyn Singer (London, United Kingdom) Moderator : Carlos Ferrando (Barcelona, Spain)

16:00 - 16:15 - HSV and CMV: to treat or not to treat? Laurent Papazian (Marseille , France)

16:15 - 16:30 - Influenza-associated respiratory failure: how to decrease mortality?


16:30 - 16:45 - Could host–directed therapy work? Benjamin Tang (Sydney, Australia)

16:45 - 17:00 - Discussion

Goal-directed therapy in sepsis [Tutorial]

17:00 - 17:30 - Goal-directed therapy in sepsis Nathan Shapiro (Boston , United States)

Tuesday 19 March 2019 - AM ROOM : Corner A

Tuesday 19 March 2019 - PM ROOM : Corner A How I manage ventilation in the COPD patient [Meet the experts]

15:00 - 15:25 - How I manage ventilation in the COPD patient Alain Mercat (Angers , France), Tobias Welte (Hannover , Germany)

How I deal with common ventilator asynchronies [Meet the experts]

15:30 - 16:00 - How I deal with common ventilator asynchronies Giacomo Bellani (Monza, Italy), Nuala Meyer (Wynnewood, United States)

Tuesday 19 March 2019 - AM ROOM : Corner B

Wednesday 20 March 2019 - AM ROOM : HLB Room

Wednesday 20 March 2019 - AM ROOM : Gold Hall In the emergency room [Standard presentation] Moderator : Jerry Nolan (Bath, United Kingdom) Moderator : Frank van Haren (Canberra, Australia)

8:00 - 8:15 - Who should be admitted and who could go home Kordo Saeed (Winchester, United Kingdom)

8:15 - 8:30 - Observational medicine: interest and limitations

Marc Sabbe (Leuven , Belgium)

8:30 - 8:45 - The challenges of the elderly patient Maaret Castren (Helsinki, Finland)

8:45 - 9:00 - Improving intubation practice

Wesley Self (Nashville, United States)

9:00 - 9:15 - Discussion

9:15 - 9:30 - Estimating ICP non–invasively: still a dream? Giuseppe Citerio (Monza, Italy)

9:30 - 9:45 - Major hemostatic problems with recreational drugs


9:45 - 10:00 - Optimal antibiotic use Michael Pulia (Madison, United States)

10:00 - 10:10 - Discussion

10:10 - 10:25 - Is qSOFA of any value here?

Rinaldo Bellomo (Melbourne, Australia)

10:25 - 10:40 - Renal failure and sepsis: think about thrombotic microangiopathy Fiorella Paladino (Naples, Italy)

10:40 - 10:55 - Nerve agents: saving the patient and protecting the staff

Michael Reade (Brisbane, Australia)

10:55 - 11:10 - A Bayesian approach to clinical decision making Nathan Shapiro (Boston , United States)

11:10 - 11:20 - Discussion

VA-ECMO in sepsis [Standard presentation] Moderator : Daniel Brodie (New York, United States) Moderator : David Grimaldi (Brussels, Belgium)

11:20 - 11:35 - ECMO for sepsis Lars Broman (Stockholm, Sweden)

11:35 - 11:50 - The role of VA-ECMO in non–cardiogenic shock

David Boldt (Los Angeles, United States)

11:50 - 12:05 - VA–ECMO for severe cardiac dysfunction in septic shock patients Alain Combes (Paris , France)

12:05 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : Gold Hall Hemodynamic monitoring [Standard presentation] Moderator : Antoine Vieillard-Baron (Boulogne-Billancourt , France) Moderator : Jan Bakker (New York, United States)

13:45 - 14:00 - Always clinical examination first Maurizio Cecconi (Rozzano, MI, Italy)

14:00 - 14:15 - New tools to evaluate peripheral perfusion


14:15 - 14:30 - Which method to measure cardiac output? Bernd Saugel (Hamburg, Germany)

14:30 - 14:45 - We should measure CVP!

Xavier Monnet (Le Kremlin-Bicêtre , France)

14:45 - 15:00 - Discussion

15:00 - 15:15 - Use transesophageal echocardiography more often Paul H Mayo (New Hyde Park, United States)

15:15 - 15:30 - Monitoring cardiac output is essential in some cases


15:30 - 15:45 - There is still a place for the PA catheter Daniel De Backer (Brussels, Belgium)

15:45 - 16:00 - Discussion

16:00 - 16:15 - What hemodynamic monitoring?

Jean-Louis Teboul (Le Kremlin-Bicêtre, France)

16:15 - 16:30 - Electrical impedance tomography can provide new insights Marcelo Amato (Sao Paulo , Brazil)

16:30 - 16:45 - Is hemodynamic monitoring cost–effective?


16:45 - 17:00 - Discussion

Can machine learning and artificial intelligence change …. [Standard presentation] Moderator : John Kellum (Pittsburgh, United States) Moderator : Brian Kavanagh (Toronto, Canada)

17:00 - 17:15 - Sepsis management? Matthieu Komorowski (London, United Kingdom)

17:15 - 17:30 - Cardiovascular management?


17:30 - 17:45 - ...any management? Vincent Liu (Oakland, United States)

17:45 - 18:00 - Discussion

Wednesday 20 March 2019 - AM ROOM : Copper Hall Delirium [Standard presentation] Moderator : Beatrice Beck-Schimmer (Zurich, Switzerland) Moderator : Philip Hopkins (London, United Kingdom)

8:00 - 8:15 - Recent advances Rinaldo Bellomo (Melbourne, Australia)

8:15 - 8:30 - A renal contribution

Marlies Ostermann (London , United Kingdom)

8:30 - 8:45 - Covert consciousness Jan Claassen (New York , United States)

8:45 - 9:00 - Therapeutic use of antipsychotics

E Wesley Ely (Nashville, United States)


9:15 - 9:30 - Delirium prevention in anesthesia and critical care Detlef Kindgen-Milles (Düsseldorf , Germany)

9:30 - 9:45 - The gut–brain connection and the ´´psychobiome”


9:45 - 10:00 - Influence of monotony on ICU recovery John J Marini (St Paul, United States)

10:00 - 10:15 - Discussion

10:15 - 10:35 - Break

Should I buy a calorimeter? [Standard presentation] Moderator : Juan B. Ochoa (Danville, United States) Moderator : Andreas Faltlhauser (Weiden in der Oberpfalz, Germany)

10:35 - 10:50 - Indirect calorimetry is the solution to optimal feeding Elisabeth De Waele (Brussels, Belgium)

10:50 - 11:05 - Indirect calorimetry does not indicate what the patient needs


11:05 - 11:20 - We have new data Pierre Singer (Petah Tikva , Israel)

11:20 - 11:35 - Discussion

11:35 - 11:50 - VCO2 measured from the ventilator can suffice

Arthur van Zanten (Ede, Netherlands)

11:50 - 12:05 - Measuring energy expenditure has other applications beyond nutrition Heleen Oudemans-Van Straaten (Amsterdam , Netherlands)

12:05 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : Copper Hall Mechanical ventilation: from dyssynchrony to harmony [Standard presentation] Moderator : John J Marini (St Paul, United States) Moderator : Niall Ferguson (Toronto , Canada)

13:45 - 14:00 - Different breathing patterns Elias N Baedorf Kassis (Boston, United States)

14:00 - 14:15 - Mechanisms of occult lung injury from breath stacking

Jeremy Beitler (New York, United States)

14:15 - 14:30 - Which asynchronies have the greatest potential for causing injury? Robert M Kacmarek (Boston, United States)

14:30 - 14:40 - Discussion

14:40 - 14:55 - Ventilator waveforms to detect, treat and prevent

Francesco Mojoli (Pavia, Italy)

14:55 - 15:10 - Partial muscle relaxation is the solution Diederik Gommers (Rotterdam, Netherlands)

15:10 - 15:25 - Monitoring of sedation and paralysis using P/V loops of the chest wall

Elias N Baedorf Kassis (Boston, United States)

15:25 - 15:35 - Discussion

15:35 - 15:50 - I found a ROSE B Taylor Thompson (Boston , United States)

15:50 - 16:05 - How I interpret the ROSE study on neuromuscular blocking agents

Laurent Papazian (Marseille , France)

16:05 - 16:20 - Patients can breathe like BIRDS Alain Mercat (Angers , France)

16:20 - 16:35 - So... spontaneous breathing or not?

John P Kress (Chicago, United States)

16:35 - 16:50 - Discussion

16:50 - 17:05 - Break

Major head trauma [Clinical vignettes] Moderator : Mauro Oddo (Lausanne , Switzerland)

17:05 - 17:35 - Major head trauma David Menon (Cambridge , United Kingdom), Nino Stocchetti (Milan , Italy), Fabio S. Taccone (Brussels ,

Belgium)

Simplifying pneumonia therapy: a single algorithm for all [Plenary lecture] 17:40 - 18:00 - Simplifying pneumonia therapy: a single algorithm for all

Michael S Niederman (New York, United States)

Wednesday 20 March 2019 - AM ROOM : Salle M (Bozar) Sleeping in the ICU [Standard presentation] Moderator : Carole Ichai (Nice, France) Moderator : Matthieu Jabaudon (Clermont-Ferrand, France)

8:00 - 8:15 - Sleep is important Olivier Huet (Brest, France)

8:15 - 8:30 - ICU patients do not sleep well

Elizabeth Wilcox (Toronto, Canada)

8:30 - 8:45 - How to get patients to sleep? Michael Reade (Brisbane, Australia)

8:45 - 9:00 - Let us apply early goal-directed sleep

Edward Litton (Perth, Australia)


Mechanical ventilation in non-ARDS patients [Standard presentation] Moderator : Francesco Mojoli (Pavia, Italy) Moderator : Fernando Suarez Sipmann (Madrid , Spain)

9:15 - 9:30 - How we ventilate patients Rinaldo Bellomo (Melbourne, Australia)

9:30 - 9:45 - Low tidal volume ventilation

Michelle N Gong (New York, United States)

9:45 - 10:00 - Evaluating lung and chest wall mechanics Alain Mercat (Angers , France)

10:00 - 10:15 - Discussion

10:15 - 10:30 - Monitoring based on Paw and flow time tracing

Jean-Christophe Richard (Annecy, France)

10:30 - 10:45 - Importance of expiratory efforts and/or respiratory training Elias N Baedorf Kassis (Boston, United States)

10:45 - 11:00 - Importance of reverse triggering


11:00 - 11:15 - Discussion

11:15 - 11:30 - How to ventilate the obese patient Paolo Pelosi (Genoa , Italy)

11:30 - 11:45 - Optimal aerosol therapy

Stephan Ehrmann (Tours , France)

11:45 - 12:00 - Gas administration: when and how Dean R Hess (Danvers, United States)

12:00 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : Salle M (Bozar) Preventing renal failure [Standard presentation] Moderator : Lui Forni (Guilford, United Kingdom) Moderator : Eric Hoste (Ghent , Belgium)

13:45 - 14:00 - Beyond blood pressure Michael Joannidis (Innsbruck , Austria)

14:00 - 14:15 - Renal perfusion and oxygenation

Sven-Erik Ricksten (Gothenburg, Sweden)

14:15 - 14:30 - Adjusting positive pressure ventilation Matthias Heringlake (Lübeck , Germany)

14:30 - 14:40 - Discussion

14:40 - 14:55 - Amino acids?

Rinaldo Bellomo (Melbourne, Australia)

14:55 - 15:10 - Albumin? Christian J Wiedermann (Innsbruck, Austria)

15:10 - 15:25 - Erythropoietin?

Markus Skrifvars (Helsinki, Finland)

15:25 - 15:40 - Do we need bundles? Alexander Zarbock (Münster, Germany)

15:40 - 15:55 - Discussion

15:55 - 16:10 - Break

When I give albumin (or not) [Standard presentation] Moderator : Christian J Wiedermann (Innsbruck, Austria) Moderator : Manu Malbrain (Brussels, Belgium)

16:10 - 16:25 - In surgery and in burns Robert G Hahn (Södertälje, Sweden)

16:25 - 16:40 - In sepsis

Pietro Caironi (Turin, Italy)

16:40 - 16:55 - In ARDS Greg Martin (Atlanta, United States)

16:55 - 17:05 - Discussion

17:05 - 17:20 - In cirrhosis


17:20 - 17:35 - in renal replacement therapy Ravindra Mehta (La Jolla, United States)

17:35 - 17:50 - Influence on renal function

Michael Joannidis (Innsbruck , Austria)

17:50 - 18:00 - Discussion

Wednesday 20 March 2019 - AM ROOM : Tent Cardiovascular pathophysiology: the basics [Standard presentation] Moderator : Paul H Mayo (New Hyde Park, United States)

8:00 - 8:15 - Venous return Maurizio Cecconi (Rozzano, MI, Italy)

8:15 - 8:30 - Systemic filling pressures


8:30 - 8:45 - Pulmonary hypertension and right heart failure Harm Jan Bogaard (Amsterdam, Netherlands)

8:45 - 9:00 - LVEF: love it or leave it ?



9:15 - 9:30 - Ventriculo–arterial coupling Fabio Guarracino (Pisa, Italy)

9:30 - 9:45 - Hemodynamic effects of intra–abdominal hypertension


9:45 - 10:00 - How increasing airway pressure influences abdominal perfusion Stephan Jakob (Bern, Switzerland)

10:00 - 10:15 - Regulation of blood flow distribution

Michael R. Pinsky (Pittsburgh, United States)

10:15 - 10:30 - Discussion

10:30 - 10:45 - Break

We need new renal biomarkers to improve care of patients at risk of acute kidney injury [Pro-con debate] Moderator : Claudio Ronco (Vicenza, Italy)

10:45 - 11:15 - We need new renal biomarkers to improve care of patients at risk of acute kidney injury PRO Alexander Zarbock (Münster, Germany)

CON Ravindra Mehta (La Jolla, United States)

Pathophysiology of brain injury [Standard presentation] Moderator : Mauro Oddo (Lausanne , Switzerland) Moderator : Robert G Hahn (Södertälje, Sweden)

11:15 - 11:30 - Altered cerebral autoregulation David Menon (Cambridge , United Kingdom)

11:30 - 11:45 - Basic alterations in CNS trauma Marek Mirski (Baltimore, United States)

11:45 - 12:00 - Pathophysiology of postanoxic brain damage

Jonathan Elmer (Pittsburgh, United States)

12:00 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : Tent Designs and end-points for clinical trials [Standard presentation] Moderator : Luciano Gattinoni (Göttingen, Germany) Moderator : Alain Combes (Paris , France)

13:45 - 14:00 - Challenges in RCT design Michael W Donnino (Boston, United States)

14:00 - 14:15 - Patient–important outcomes

Stephane Gaudry (Colombes, France)

14:15 - 14:30 - Is quality of life the right outcome? Timothy Walsh (Edinburgh , United Kingdom)

14:30 - 14:45 - Understanding renal outcomes


14:45 - 15:00 - Discussion

Blood purification [Standard presentation] Moderator : Kordo Saeed (Winchester, United Kingdom) Moderator : Jesus F Bermejo Martin (Valladolid, Spain)

15:00 - 15:15 - Is the rationale strong enough? Zsolt Molnar (Szeged , Hungary)

15:15 - 15:30 - CAH-CHDDF techniques

Hiroyuki Hirasawa (Chiba , Japan)

15:30 - 15:45 - Which inflammatory substances can we effectively remove? Marlies Ostermann (London , United Kingdom)

15:45 - 16:00 - Is it ready for routine use?

Antoine Schneider (Lausanne, Switzerland)

16:00 - 16:15 - Discussion

16:15 - 16:30 - In sepsis and MOF Steffen R. Mitzner (Rostock , Germany)

16:30 - 16:45 - Extracorporeal pathogen elimination is on the horizon

Stefan Büttner (Frankfurt am Main, Germany)

16:45 - 17:00 - Beyond mitigating the inflammatory response Andreas Faltlhauser (Weiden in der Oberpfalz, Germany)

17:00 - 17:15 - The promise of medium cut-off membranes

Claudio Ronco (Vicenza, Italy)

17:15 - 17:30 - Discussion

Stewart acid-base [Tutorial] 17:30 - 18:00 - Stewart´s acid–base


Wednesday 20 March 2019 - AM ROOM : Silver Hall Massive bleeding/trauma [Standard presentation] Moderator : Donat R Spahn (Zurich , Switzerland) Moderator : Theresa Mariero Olasveengen (Oslo, Norway)

8:00 - 8:15 - Trauma-induced coagulopathy Herbert Schöchl (Salzburg, Austria)

8:15 - 8:30 - Tranexamic acid


8:30 - 8:45 - Platelets Marc Maegele (Cologne , Germany)


8:55 - 9:10 - Fibrinogen

Herbert Schöchl (Salzburg, Austria)

9:10 - 9:25 - Fresh frozen plasma Jerrold H Levy (Durham, United States)

9:25 - 9:40 - Lyophilized plasma


9:40 - 9:55 - Coagulation factor concentrates Oliver Grottke (Aachen, Germany)

9:55 - 10:10 - Visco-elastic test algorithms

Nicole Juffermans (Amsterdam , Netherlands)

10:10 - 10:20 - Discussion

Rapid response systems [Standard presentation] Moderator : Steffen R. Mitzner (Rostock , Germany) Moderator : Laurie Morrison (Toronto , Canada)

10:20 - 10:35 - Early warning scores Vincent Liu (Oakland, United States)

10:35 - 10:50 - A nurse’s perspective John Welch (London , United Kingdom)

10:50 - 11:05 - A physiotherapist’s perspective

Michelle Norrenberg (Brussels , Belgium)

11:05 - 11:15 - Discussion

11:15 - 11:30 - A doctor’s perspective Rinaldo Bellomo (Melbourne, Australia)

11:30 - 11:45 - qSOFA and other clinical scoring systems

Kristina Rudd (Pittsburgh, United States)

11:45 - 12:00 - We should improve ward monitoring Frédéric Michard (Lausanne, Switzerland)

12:00 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : Silver Hall After cardiac arrest [Standard presentation] Moderator : Maaret Castren (Helsinki, Finland) Moderator : Stephan Ehrmann (Tours , France)

13:45 - 14:00 - Building systems of regionalized post–cardiac arrest care Jonathan Elmer (Pittsburgh, United States)

14:00 - 14:15 - Post–cardiac arrest shock

Alain Cariou (Paris, France)

14:15 - 14:30 - Optimal arterial pressure to limit cardiac injury Markus Skrifvars (Helsinki, Finland)

14:30 - 14:45 - Resuscitating shock by post–cardiac arrest syndrome subtype


14:45 - 15:00 - Discussion

15:00 - 15:15 - Protective ventilation: just do it! Paolo Pelosi (Genoa , Italy)

15:15 - 15:30 - Renal failure


15:30 - 15:45 - Organ donation Laurie Morrison (Toronto , Canada)

15:45 - 16:00 - Discussion

Airway challenges [Standard presentation] Moderator : Arnaud Thille (Poitiers, France) Moderator : Giacomo Bellani (Monza, Italy)

16:00 - 16:15 - Hazards of intubation in the critically ill patient Jean-Damien Ricard (Colombes, France)

16:15 - 16:30 - Help, I cannot intubate!

Samir Jaber (Montpellier, France)

16:30 - 16:45 - Combined team approach for urgent endotracheal intubation Paul H Mayo (New Hyde Park, United States)

16:45 - 17:00 - Discussion

17:00 - 17:15 - Should we intubate patients during CPR?


17:15 - 17:30 - When to perform a tracheostomy Paolo Pelosi (Genoa , Italy)

17:30 - 17:45 - Dysphagia in neurological patients

Giuseppe Citerio (Monza, Italy)

17:45 - 18:00 - Discussion

Wednesday 20 March 2019 - AM ROOM : 100 Hall Perioperative optimization [Tutorial]

8:00 - 8:30 - Perioperative optimization Matthias Heringlake (Lübeck , Germany)

Heterogeneity in sepsis [Standard presentation] Moderator : Timothy Walsh (Edinburgh , United Kingdom) Moderator : Djillali Annane (Garches , France)

8:35 - 8:50 - Is sepsis so heterogeneous? Vincent Liu (Oakland, United States)

8:50 - 9:05 - ICU-acquired immune suppression


9:05 - 9:20 - Staging and stratification: we can do better than ´´sepsis´´ and ´´ARDS´´ John C Marshall (Toronto , Canada)


9:35 - 9:50 - Cardiovascular phenotypes in septic shock: a clustering approach.

Antoine Vieillard-Baron (Boulogne-Billancourt , France)

9:50 - 10:05 - Influence of race on host response and outcome Tom van der Poll (Amsterdam , Netherlands)

10:05 - 10:20 - Immune status, comorbidities and complications

Jean-Paul Mira (Paris, France)

10:20 - 10:35 - Discussion

10:35 - 10:50 - Molecular subclasses of sepsis Hector R Wong (Cincinnati , United States)

10:50 - 11:05 - Epigenetics: modifiable pathway to long–term outcomes

Greet Van den Berghe (Leuven , Belgium)

11:05 - 11:20 - Is clinical phenotyping the answer to failed trials? Christopher Seymour (Pittsburgh, United States)

11:20 - 11:35 - Discussion

11:35 - 11:45 - Break

Open lung concept in ARDS [Pro-con debate] Moderator : Matthieu Komorowski (London, United Kingdom)

11:45 - 11:55 - We are still allowed to apply it Diederik Gommers (Rotterdam, Netherlands)

11:55 - 12:05 - We should keep the lung closed B Taylor Thompson (Boston , United States)

12:05 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : 100 Hall The burden of sepsis [Standard presentation] Moderator : Thierry Calandra (Lausanne , Switzerland) Moderator : Tom van der Poll (Amsterdam , Netherlands)

13:45 - 14:00 - We must act before the hospital admission Christopher Seymour (Pittsburgh, United States)

14:00 - 14:15 - Long–term burden


14:15 - 14:30 - The approach of the US government Steven Simpson (Kansas City, United States)

14:30 - 14:45 - Discussion

14:45 - 15:00 - The approach of the French government


15:00 - 15:15 - In low– and middle–income countries Kristina Rudd (Pittsburgh, United States)

15:15 - 15:30 - Discussion

15:30 - 15:50 - Break

Fluid challenge [Standard presentation] Moderator : Fabio Guarracino (Pisa, Italy) Moderator : Olivier Huet (Brest, France)

15:50 - 16:05 - Estimating mean system filling pressure: useful at the bedside? Denise Veelo (Amsterdam , Netherlands)

16:05 - 16:20 - How to do it?

Maurizio Cecconi (Rozzano, MI, Italy)

16:20 - 16:35 - How long is it effective? Daniel De Backer (Brussels, Belgium)

16:35 - 16:50 - Also in ARDS?

Davide Chiumello (Milan , Italy)

16:50 - 17:05 - How does it affect the septic kidney? Rinaldo Bellomo (Melbourne, Australia)

17:05 - 17:20 - Discussion

Life-threatening bleeding outside the hospital [Tutorial]

17:25 - 18:00 - Life–threatening bleeding outside the hospital David Zideman (Pinner, United Kingdom)

Wednesday 20 March 2019 - AM ROOM : Terarken (Bozar) Facing the emergency [Standard presentation] Moderator : Peter Radermacher (Ulm , Germany) Moderator : Bernd Saugel (Hamburg, Germany)

8:00 - 8:15 - Anaphylactic shock Jerrold H Levy (Durham, United States)

8:15 - 8:30 - Burn resuscitation


8:30 - 8:45 - Heat stroke David Zideman (Pinner, United Kingdom)


8:55 - 9:10 - Post-partum hemorrhage


9:10 - 9:25 - Upper GI bleeding Thomas Lescot (Paris, France)

9:25 - 9:40 - Right heart failure Harm Jan Bogaard (Amsterdam, Netherlands)


9:50 - 10:05 - Break

Weaning and extubation [Standard presentation] Moderator : Gianluigi Li Bassi (Barcelona, Spain) Moderator : John Simpson (Newcastle upon Tyne, United Kingdom)

10:05 - 10:20 - Strong risk factors for failure Arnaud Thille (Poitiers, France)

10:20 - 10:35 - Limitations of current evidence-based approaches


10:35 - 10:50 - One approach does not fit all Robert M Kacmarek (Boston, United States)

10:50 - 11:00 - Discussion

11:00 - 11:15 - Cardiac failure as a cause of failure Xavier Monnet (Le Kremlin-Bicêtre , France)

11:15 - 11:30 - Does wakefulness matter?


11:30 - 11:45 - Weaning in brain injury Victoria McCredie (Toronto, Canada)

11:45 - 12:00 - Extubation on to what?

Robert M Kacmarek (Boston, United States)

12:00 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : Terarken (Bozar) Polytrauma [Standard presentation] Moderator : Nathan Shapiro (Boston , United States) Moderator : Herbert Schöchl (Salzburg, Austria)

13:45 - 14:00 - New guidelines Donat R Spahn (Zurich , Switzerland)

14:00 - 14:15 - New concepts in traumatic shock

Karim Brohi (London , United Kingdom)

14:15 - 14:30 - Responding to mass casualty incidents and civil–military cooperation Raed Arafat (Bucarst, Romania)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Damage control

Marc Maegele (Cologne , Germany)

15:00 - 15:15 - What comes after damage control John Prowle (London, United Kingdom)

15:15 - 15:30 - Contemporary coagulation management

Karim Brohi (London , United Kingdom)

15:30 - 15:45 - Discussion

15:45 - 16:00 - We need to treat endotheliopathy Jakob Stensballe (Copenhagen, Denmark)

16:00 - 16:15 - We need to control hyperglycemia

Grant Bochicchio (St Louis, United States)

16:15 - 16:30 - How to cope with acquired immunosuppression Brice Gaudillière (Stanford, United States)

16:30 - 16:45 - Discussion

Agitation in the ICU [Tutorial]

16:50 - 17:20 - Agitation in the ICU Timothy Walsh (Edinburgh , United Kingdom)

Wednesday 20 March 2019 - AM ROOM : 400 Hall Non-invasive ventilation and high-flow nasal oxygen [Standard presentation] Moderator : Niall Ferguson (Toronto , Canada) Moderator : Davide Chiumello (Milan , Italy)

8:00 - 8:15 - How to choose in acute hypoxemic respiratory failure Arnaud Thille (Poitiers, France)

8:15 - 8:30 - How unsafe is it in hypoxemic respiratory failure?


8:30 - 8:45 - Safety depends on transpulmonary pressure Marco V Ranieri (Bologna, Italy)


9:00 - 9:15 - Can we use nasal high-flow oxygen during hypercapnic respiratory failure?

Jean-Damien Ricard (Colombes, France)

9:15 - 9:30 - Head helmets: pros and cons Giacomo Bellani (Monza, Italy)

9:30 - 9:45 - Helmets, masks and high-flow nasal oxygen: how to choose

Antonio Pesenti (Milan , Italy)


9:55 - 10:10 - Which strategy in postoperative patients? Samir Jaber (Montpellier, France)

10:10 - 10:25 - Aerosol delivery

Dean R Hess (Danvers, United States)

10:25 - 10:40 - When comfort is the only goal J Randall Curtis (Seattle, United States)

10:40 - 10:55 - Discussion

10:55 - 11:10 - Break

Procalcitonin monitoring to guide antibiotic discontinuation [Pro-con debate] Moderator : Steven Simpson (Kansas City, United States)

11:10 - 11:40 - Procalcitonin monitoring to guide antibiotic discontinuation CON Tobias Welte (Hannover , Germany)

PRO Jesus F Bermejo Martin (Valladolid, Spain)

Tailoring nutrition therapy to the patient’s needs [Tutorial] 11:45 - 12:15 - Tailoring nutrition therapy to the patient’s needs Paul Wischmeyer (Durham, United States)

Wednesday 20 March 2019 - PM ROOM : 400 Hall Optimizing perioperative care [Standard presentation] Moderator : Massimo Antonelli (Rome, Italy)

13:45 - 14:00 - Emergency surgery: how do we manage anticoagulated patients? Sam Schulman (Hamilton, Canada)

14:00 - 14:15 - Optimal arterial pressure

Samir Jaber (Montpellier, France)

14:15 - 14:30 - Can we predict hemodynamic instability? Thomas Scheeren (Groningen, Netherlands)

14:30 - 14:45 - A hypotension probability indicator

Denise Veelo (Amsterdam , Netherlands)

14:45 - 14:55 - Discussion

14:55 - 15:10 - How to guide fluid management Michael Sander (Giessen, Germany)

15:10 - 15:25 - Protocolized versus personalized hemodynamic management

Bernd Saugel (Hamburg, Germany)

15:25 - 15:40 - Perioperative coagulation Donat R Spahn (Zurich , Switzerland)

15:40 - 15:50 - Discussion

15:50 - 16:05 - Postoperative nutrition support

Michael Chourdakis (Thessaloniki, Greece)

16:05 - 16:20 - Protective mechanical ventilation Paolo Pelosi (Genoa , Italy)

16:20 - 16:35 - Optimal postoperative ventilatory support

Carlos Ferrando (Barcelona, Spain)

16:35 - 16:50 - CPAP to PREVENT postoperative complications Marco V Ranieri (Bologna, Italy)

16:50 - 17:05 - Discussion

17:05 - 17:20 - Patients with liver disease

Gianni Biancofiore (Pisa, Italy)

17:20 - 17:35 - Caring for frail patients after high-risk surgery Hannah Wunsch (Toronto, Canada)

17:35 - 17:50 - Pretreatment with levosimendan in cardiac surgery

Matthias Heringlake (Lübeck , Germany)

17:50 - 18:00 - Discussion

Wednesday 20 March 2019 - AM ROOM : Panoramic Hall It´s all about the mitochondria [Standard presentation] Moderator : Carolyn S Calfee (San Francisco , United States) Moderator : Brice Gaudillière (Stanford, United States)

8:00 - 8:15 - Bedside monitoring Mervyn Singer (London, United Kingdom)

8:15 - 8:30 - Mitochondrial dysfunction in sepsis

Arthur van Zanten (Ede, Netherlands)

8:30 - 8:45 - Cell–based therapy could target the mitochondria Benjamin Tang (Sydney, Australia)


8:55 - 9:10 - Mitochondrial oxygen tension could guide transfusion


9:10 - 9:25 - Metformin as a potential therapy Jean-Charles Preiser (Brussels , Belgium)

9:25 - 9:40 - Metabolic resuscitation of the mitochondrion

Michael W Donnino (Boston, United States)


It´s all in the microcirculation [Standard presentation] Moderator : Christian J Wiedermann (Innsbruck, Austria) Moderator : Stephen M Pastores (New York, United States)

9:55 - 10:10 - What´s new down there? Can Ince (Amsterdam , Netherlands)

10:10 - 10:25 - Endothelial injury in sepsis and renal failure

Suvi Vaara (helsinki, Finland)

10:25 - 10:40 - How fluid resuscitation can alter the glycocalyx Nathan Shapiro (Boston , United States)

10:40 - 10:55 - Common features of endothelial dysfunction in sepsis and chronic disease

Jesus F Bermejo Martin (Valladolid, Spain)

10:55 - 11:05 - Discussion

11:05 - 11:20 - It´s useful to monitor the microcirculation in shock Jacques Duranteau (Le Kremlin-Bicêtre , France)

11:20 - 11:35 - It´s also helpful during surgery

Denise Veelo (Amsterdam , Netherlands)

11:35 - 11:50 - Resuscitation of endotheliopathy is a new target Jakob Stensballe (Copenhagen, Denmark)

11:50 - 12:05 - Vitamin C is the next potential therapy

Daniel De Backer (Brussels, Belgium)

12:05 - 12:15 - Discussion

Wednesday 20 March 2019 - PM ROOM : Panoramic Hall Making a better ICU [Standard presentation] Moderator : Jean-Paul Mira (Paris, France) Moderator : Anthony McLean (Sydney , Australia)

13:45 - 14:00 - Optimal ICU design Philip Hopkins (London, United Kingdom)

14:00 - 14:15 - Are dedicated neurocritical care units really necessary?

Victoria McCredie (Toronto, Canada)

14:15 - 14:30 - How many doctors? How many nurses? Hannah Wunsch (Toronto, Canada)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Do we all need advance practice providers?

Stephen M Pastores (New York, United States)

15:00 - 15:15 - How about physiotherapists? Gianluigi Li Bassi (Barcelona, Spain)

15:15 - 15:30 - Simulation to decrease stress in ICU nurses


15:30 - 15:45 - How nurses could be more involved John Welch (London , United Kingdom)

15:45 - 16:00 - Discussion

16:00 - 16:15 - Break

Managing anticoagulation [Standard presentation] Moderator : Beverley Hunt (London , United Kingdom) Moderator : Marc Maegele (Cologne , Germany)

16:15 - 16:30 - From the old, to the newest David Boldt (Los Angeles, United States)

16:30 - 16:45 - How to estimate the effect of direct oral anticoagulants Sam Schulman (Hamilton, Canada)

16:45 - 17:00 - Managing bleeding with the new anticoagulants

Jerrold H Levy (Durham, United States)

17:00 - 17:15 - Discussion

17:15 - 17:30 - Reversal of anticoagulation in acute stroke Marek Mirski (Baltimore, United States)

17:30 - 17:45 - Do we need antidotes to reverse anticoagulation?

Oliver Grottke (Aachen, Germany)

17:45 - 18:00 - Discussion

Wednesday 20 March 2019 - AM ROOM : Studio Room Quality of care [Standard presentation] Moderator : Thomas Scheeren (Groningen, Netherlands) Moderator : Laveena Munshi (Toronto, Canada)

8:00 - 8:15 - Patient-centered outcomes in pediatrics: what´s important to patients and families Karen Choong (Hamilton, Canada)

8:15 - 8:30 - Are week–end ICU admissions associated with higher mortality?

Raimund Helbok (Innsbruck, Austria)

8:30 - 8:45 - Geriatricizing the ICU: the path forward Lauren Ferrante (New Haven, United States)


9:00 - 9:15 - How we eliminated pressure ulcers

John Welch (London , United Kingdom)

9:15 - 9:30 - Patient safety in the ICU: the (un)feasibility of zero Brian Kavanagh (Toronto, Canada)


9:40 - 9:55 - Break

Guidelines and bundles [Standard presentation] Moderator : Elie Azoulay (Paris , France) Moderator : Michael A Matthay (San Francisco, United States)

9:55 - 10:10 - How to adapt sepsis guidelines Ricard Ferrer (Barcelona, Spain)

10:10 - 10:25 - Pediatric sepsis: does time still matter?

Christopher Seymour (Pittsburgh, United States)

10:25 - 10:40 - Protocols: misalignment and misattribution Brian Kavanagh (Toronto, Canada)

10:40 - 10:55 - Discussion

10:55 - 11:10 - Overcoming barriers to personalized medicine in the ICU

Nuala Meyer (Wynnewood, United States)

11:10 - 11:25 - Sepsis outcomes and fake news Mervyn Singer (London, United Kingdom)

11:25 - 11:40 - Discussion

Early resuscitation of sepsis (T) [Tutorial]

11:45 - 12:15 - Early resuscitation of sepsis Wesley Self (Nashville, United States)

Wednesday 20 March 2019 - PM ROOM : Studio Room Predicting major complications [Standard presentation] Moderator : Nuala Meyer (Wynnewood, United States) Moderator : Michael A Matthay (San Francisco, United States)

13:30 - 13:45 - Does qSOFA predict sepsis outcomes? Benjamin Tang (Sydney, Australia)

13:45 - 14:00 - Predictive analytics: beyond the buzz


14:00 - 14:15 - We can develop better predictive scores Vincent Liu (Oakland, United States)

14:15 - 14:30 - Predicting sepsis: bedside chart analysis


14:30 - 14:45 - Discussion

14:45 - 15:00 - Predicting sepsis: artificial intelligence Matthieu Komorowski (London, United Kingdom)

15:00 - 15:15 - Predicting renal failure

Geert Meyfroidt (Leuven , Belgium)

15:15 - 15:30 - Predicting cardiorespiratory failure Michael R. Pinsky (Pittsburgh, United States)

15:30 - 15:45 - Predicting respiratory failure


15:45 - 16:00 - Discussion

16:00 - 16:20 - Break

Complications of chemotherapy [Tutorial] 16:20 - 16:50 - Complications of chemotherapy

Stephen M Pastores (New York, United States)

Should we guide resuscitation by monitoring the microcirculation? [Pro-con debate] Moderator : Stephen M Pastores (New York, United States)

16:55 - 17:25 - Should we guide resuscitation by monitoring the microcirculation? PRO Jacques Duranteau (Le Kremlin-Bicêtre , France)

CON Xavier Monnet (Le Kremlin-Bicêtre , France)

Lactate levels can guide therapy [Pro-con debate] Moderator : Hector R Wong (Cincinnati , United States)

17:30 - 18:00 - Lactate levels can guide therapy PRO Jan Bakker (New York, United States)

CON Mervyn Singer (London, United Kingdom)

Wednesday 20 March 2019 - AM ROOM : Corner A

Wednesday 20 March 2019 - PM ROOM : Corner A How I feed my patient [Meet the experts]

14:00 - 14:25 - How I feed my patient Marianne Chapman (Adelaide , Australia), Arthur van Zanten (Ede, Netherlands)

RRT: practical aspects [Meet the experts]

14:30 - 14:55 - RRT: practical aspects Patrick Honoré (Bruxelles, Belgium), Detlef Kindgen-Milles (Düsseldorf , Germany)

How I evaluate diaphragmatic function [Meet the experts]

16:00 - 16:25 - How I evaluate diaphragm function Heinrich Groesdonk (Homburg / Saar, Germany), Tom Schepens (Edegem, Belgium)

Respiratory failure in an immunocompromised patient [Meet the experts]

16:30 - 17:00 - Respiratory failure in an immunocompromised patient Elie Azoulay (Paris , France), Laveena Munshi (Toronto, Canada)

Wednesday 20 March 2019 - AM ROOM : Corner B Cardiac arrest (ME) [Meet the experts]

11:30 - 12:00 - Cardiad arrest Markus Skrifvars (Helsinki, Finland), Theresa Mariero Olasveengen (Oslo, Norway)

Wednesday 20 March 2019 - PM ROOM : Corner B Drugs in CPR [Meet the experts]

14:30 - 14:55 - Drugs in CPR Theresa Mariero Olasveengen (Oslo, Norway), Lars Wiuff Andersen (Aarhus, Denmark)

Thursday 21 March 2019 - AM ROOM : HLB Room

Thursday 21 March 2019 - AM ROOM : Gold Hall Traumatic brain injury [Standard presentation] Moderator : Marek Mirski (Baltimore, United States) Moderator : Giuseppe Citerio (Monza, Italy)

8:00 - 8:15 - How to better characterize it Nino Stocchetti (Milan , Italy)

8:15 - 8:30 - How urgent is an urgent craniotomy?


8:30 - 8:45 - Minimizing secondary injury Victoria McCredie (Toronto, Canada)


9:00 - 9:15 - Optimizing brain perfusion

Mauro Oddo (Lausanne , Switzerland)

9:15 - 9:30 - Avoiding hyperoxia Peter Radermacher (Ulm , Germany)

9:30 - 9:45 - Coping with coagulopathy

Herbert Schöchl (Salzburg, Austria)


10:00 - 10:15 - Poster awards

10:15 - 10:30 - Prognostication of outcomes Jan Claassen (New York , United States)

10:30 - 10:45 - Modulating neuroinflammation is the future

David Menon (Cambridge , United Kingdom)

10:45 - 11:00 - Big data can improve care Victoria McCredie (Toronto, Canada)

11:00 - 11:15 - Discussion

How I manage a patient with acute respiratory failure [Clinical vignettes]

11:20 - 11:50 - How I manage a patient with acute respiratory failure Laurent Brochard (Toronto, Canada), Diederik Gommers (Rotterdam, Netherlands), Dean R Hess (Danvers,

United States), Antonio Pesenti (Milan , Italy)

Misapplication of severity of illness scores [Plenary lecture] 11:55 - 12:15 - Misapplication of severity of illness scores

Michael W Donnino (Boston, United States)

Thursday 21 March 2019 - PM ROOM : Gold Hall Acute renal failure [Standard presentation] Moderator : Torsten Slowinski (Berlin, Germany) Moderator : Stephane Gaudry (Colombes, France)

13:45 - 14:00 - Sepsis and renal failure: a bidirectional relationship John Kellum (Pittsburgh, United States)

14:00 - 14:15 - The kidney is out of breath

Can Ince (Amsterdam , Netherlands)

14:15 - 14:30 - Update on rhabdomyolysis Jacques Duranteau (Le Kremlin-Bicêtre , France)

14:30 - 14:45 - Contrast-associated renal failure: still a problem?


14:45 - 15:00 - Discussion

15:00 - 15:15 - How the kidneys recover Carole Ichai (Nice, France)

15:15 - 15:30 - Nutritional support

Eric Hoste (Ghent , Belgium)

15:30 - 15:45 - Promoting recovery by nutritional adjustment Ravindra Mehta (La Jolla, United States)

15:45 - 16:00 - Long–term outcomes


16:00 - 16:15 - Discussion

16:15 - 16:25 - Break

CRRT [Standard presentation] Moderator : Sven-Erik Ricksten (Gothenburg, Sweden) Moderator : Suvi Vaara (helsinki, Finland)

16:25 - 16:40 - Quality control Claudio Ronco (Vicenza, Italy)

16:40 - 16:55 - Timing: there are some new elements Stephane Gaudry (Colombes, France)

16:55 - 17:05 - Discussion

17:05 - 17:20 - When to use hybrid therapy


17:20 - 17:35 - When to stop Lui Forni (Guilford, United Kingdom)

17:35 - 17:50 - Could biomarkers predict RRT requirements?


17:50 - 18:00 - Discussion

Thursday 21 March 2019 - AM ROOM : Copper Hall Assessing renal function [Standard presentation] Moderator : Claudio Ronco (Vicenza, Italy) Moderator : Detlef Kindgen-Milles (Düsseldorf , Germany)

8:00 - 8:15 - Time to revisit the clinical definitions John Kellum (Pittsburgh, United States)

8:15 - 8:30 - There are subphenotypes

Ravindra Mehta (La Jolla, United States)

8:30 - 8:45 - Contrast–enhanced ultrasound to assess the microcirculation Jacques Duranteau (Le Kremlin-Bicêtre , France)


8:55 - 9:10 - How nitrogen metabolism can influence the diagnosis


9:10 - 9:25 - Renal biomarkers: tools or tests? Lui Forni (Guilford, United Kingdom)

9:25 - 9:40 - Pro–enkephalin as a new functional kidney biomarker

Peter Pickkers (Nijmegen, Netherlands)

9:40 - 9:55 - Can frequent creatinine measurements help? Suvi Vaara (helsinki, Finland)


Fluids and kidney [Standard presentation] Moderator : John Kellum (Pittsburgh, United States) Moderator : Ravindra Mehta (La Jolla, United States)

10:10 - 10:25 - My patient is oliguric: is it renal impairment? Lui Forni (Guilford, United Kingdom)

10:25 - 10:40 - We should assess renal blood flow


10:40 - 10:55 - Diuretics should be abandoned Alexander Zarbock (Münster, Germany)

10:55 - 11:05 - Discussion

11:05 - 11:20 - We can now better predict safety and efficacy of loop diuretics

Steffen R. Mitzner (Rostock , Germany)

11:20 - 11:35 - Fluid management in renal failure Marlies Ostermann (London , United Kingdom)

11:35 - 11:50 - Restrict fluids?


11:50 - 12:05 - Watch the venous pressures! Patrick Honoré (Bruxelles, Belgium)

12:05 - 12:15 - Discussion

Thursday 21 March 2019 - PM ROOM : Copper Hall Did you say ‘antibiotic stewardship´? [Standard presentation] Moderator : John G Laffey (Galway, Ireland) Moderator : Michael S Niederman (New York, United States)

13:45 - 14:00 - Sense and nonsense of stewardship Tobias Welte (Hannover , Germany)

14:00 - 14:15 - We can reduce antibiotic exposure

Jan De Waele (Ghent , Belgium)

14:15 - 14:30 - Markers can avoid unnecessary use of antibiotics´´just in case´´ Kordo Saeed (Winchester, United Kingdom)

14:30 - 14:45 - In whom should I use new antimicrobials empirically?

Matteo Bassetti (Udine, Italy)

14:45 - 15:00 - Nebulized antibiotics in VAP: clinical data Antoni Torres (Barcelona , Spain)

15:00 - 15:15 - Discussion

15:15 - 15:30 - Inhaled antibiotic therapy: how to do it


15:30 - 15:45 - Optimal treatment of ESBL infections Jean-François Timsit (Paris, France)

15:45 - 16:00 - Therapeutic drug monitoring is important

Yok-Ai Que (Bern, Switzerland)

16:00 - 16:15 - Antibiotics: how long should a course be? Mervyn Singer (London, United Kingdom)

16:15 - 16:30 - From feedback strategies to artificial intelligence

Jeroen Schouten (Nijmegen, Netherlands)

16:30 - 16:45 - Discussion

16:45 - 17:00 - Break

Tidal volume of 6 ml/kg for every ventilated patient? [Round table] Moderator : John J Marini (St Paul, United States)

17:00 - 18:00 - Tidal volume of 6 cc/kg for every ventilated patient? Michelle N Gong (New York, United States), Samir Jaber (Montpellier, France), Alain Mercat (Angers ,

France), Paolo Pelosi (Genoa , Italy)

Thursday 21 March 2019 - AM ROOM : Salle M (Bozar) New therapies for sepsis [Standard presentation] Moderator : John C Marshall (Toronto , Canada) Moderator : Greg Martin (Atlanta, United States)

8:00 - 8:15 - Polymyxin B hemoperfusion: from Euphas to Euphrates Massimo Antonelli (Rome, Italy)

8:15 - 8:30 - Is endotoxin a potential therapeutic target?

Steffen R. Mitzner (Rostock , Germany)

8:30 - 8:45 - The adrenomellulin antibody adrecizumab Peter Pickkers (Nijmegen, Netherlands)


9:00 - 9:15 - Cholesterol therapy?

Mervyn Singer (London, United Kingdom)

9:15 - 9:30 - Fever control? Nicole Juffermans (Amsterdam , Netherlands)

9:30 - 9:45 - Immunostimulating strategies



10:00 - 10:15 - A further look at recombinant alkaline phosphatase Peter Pickkers (Nijmegen, Netherlands)

10:15 - 10:30 - Recombinant thrombomodulin


10:30 - 10:45 - Effects of thrombomodulin administration on mediators Jawed Fareed (Maywood, United States)

10:45 - 11:00 - The HCG derivative EA-230

Peter Pickkers (Nijmegen, Netherlands)

11:00 - 11:15 - Cell-based therapies John G Laffey (Galway, Ireland)

11:15 - 11:30 - Discussion

11:30 - 11:45 - Break

EEG for the general intensivist [Tutorial]

11:45 - 12:15 - EEG for the general intensivist Jonathan Elmer (Pittsburgh, United States)

Thursday 21 March 2019 - PM ROOM : Salle M (Bozar) CO2 monitoring [Standard presentation] Moderator : Marianne Chapman (Adelaide , Australia) Moderator : Olivier Huet (Brest, France)

13:45 - 14:00 - Intraorgan PCO2 Tor Inge Tonnessen (Oslo , Norway)

14:00 - 14:15 - EtCO2 Luciano Gattinoni (Göttingen, Germany)

14:15 - 14:30 - CO2 production? Heleen Oudemans-Van Straaten (Amsterdam , Netherlands)

14:30 - 14:45 - CO2 kinetics?

Fernando Suarez Sipmann (Madrid , Spain)

14:45 - 15:00 - Discussion

15:00 - 15:15 - Break

New CRRT equipment and new features [Plenary lecture] 15:15 - 15:35 - New CRRT equipment and new features

Claudio Ronco (Vicenza, Italy)

Extracorporeal CO2 removal (ECCO2 R) [Standard presentation] Moderator : Luciano Gattinoni (Göttingen, Germany) Moderator : Michael Quintel (Göttingen , Germany)

15:35 - 15:50 - Use in COPD Antonio Pesenti (Milan , Italy)

15:50 - 16:05 - Use in ARDS

Marco V Ranieri (Bologna, Italy)

16:05 - 16:20 - It can control respiratory drive Christian Karagiannidis (Cologne, Germany)

16:20 - 16:35 - It can decrease mechanical power Davide Chiumello (Milan , Italy)

16:35 - 16:50 - Discussion

16:50 - 17:05 - CVVH can already remove CO2 Elisabeth De Waele (Brussels, Belgium)

17:05 - 17:20 - What clinical trial do we need?


17:20 - 17:30 - Discussion

Management of acute liver failure [Tutorial] 17:30 - 18:00 - Management of acute liver failure


Thursday 21 March 2019 - AM ROOM : Tent VILI, VIDI, VIKI [Standard presentation] Moderator : Michael Quintel (Göttingen , Germany) Moderator : Philip Hopkins (London, United Kingdom)

8:00 - 8:15 - Can the lung be adapted to resist VILI? John J Marini (St Paul, United States)

8:15 - 8:30 - Sizing the ARDS ´´baby lung´´ at the bedside


8:30 - 8:45 - Tidal volume scaling by end–expiratory lung volume Giacomo Bellani (Monza, Italy)


8:55 - 9:10 - Mechanical power is related to outcome

Luciano Gattinoni (Göttingen, Germany)

9:10 - 9:25 - Assisted ventilation minimizes VILI in ARDS Paolo Pelosi (Genoa , Italy)

9:25 - 9:40 - Volutrauma vs atelectrauma



9:50 - 10:05 - Expiratory energetics are neglected John J Marini (St Paul, United States)

10:05 - 10:20 - Cardiac contributions are neglected


10:20 - 10:35 - Ventilator–induced diaphragm dysfunction (VIDI) Samir Jaber (Montpellier, France)

10:35 - 10:50 - Ventilator–induced kidney injury (VIKI)


10:50 - 11:05 - Discussion

11:05 - 11:20 - Break

My ARDS patient has right ventricular failure. [Clinical vignettes] Moderator : Xavier Monnet (Le Kremlin-Bicêtre , France)

11:20 - 11:50 - My ARDS patient has right ventricular failure Daniel De Backer (Brussels, Belgium), Robert M Kacmarek (Boston, United States), Paul H Mayo (New Hyde

Park, United States), Antoine Vieillard-Baron (Boulogne-Billancourt , France)

Precision critical care medicine [Plenary lecture] 11:55 - 12:15 - Precision critical care medicine

Hector R Wong (Cincinnati , United States)

Thursday 21 March 2019 - PM ROOM : Tent Setting PEEP [Standard presentation] Moderator : Laurent Papazian (Marseille , France) Moderator : Francesco Mojoli (Pavia, Italy)

13:45 - 14:00 - PEEP is a component of mechanical power Michael Quintel (Göttingen , Germany)

14:00 - 14:15 - Slow flow pressure–volume loops are useful

Elias N Baedorf Kassis (Boston, United States)

14:15 - 14:30 - The decremental PEEP trial, with esophageal manometry and EIT Robert M Kacmarek (Boston, United States)

14:30 - 14:45 - The PEEP/FiO2 table is still the best

B Taylor Thompson (Boston , United States)

14:45 - 15:00 - Should be guided by driving pressure Marcelo Amato (Sao Paulo , Brazil)

15:00 - 15:15 - There is no ideal PEEP in high risk surgical patients

Carlos Ferrando (Barcelona, Spain)

15:15 - 15:30 - Discussion

15:30 - 15:45 - Personalizing PEEP Nuala Meyer (Wynnewood, United States)

15:45 - 16:00 - Low PEEP in ARDS to minimize VILI

Paolo Pelosi (Genoa , Italy)

16:00 - 16:15 - Right heart failure and PEEP: not always a problem Robert M Kacmarek (Boston, United States)

16:15 - 16:30 - What have we learned for the past 50 years


16:30 - 16:45 - Discussion

16:45 - 16:55 - Break

Burn injury [Tutorial] 16:55 - 17:25 - Burn injury


Thrombocytopenia in critical care [Tutorial] 17:30 - 18:00 - Thrombocytopenia in critical care

Tina Dutt (Liverpool, United Kingdom)

Thursday 21 March 2019 - AM ROOM : Silver Hall Bacterial challenges [Standard presentation] Moderator : Jeroen Schouten (Nijmegen, Netherlands) Moderator : Tobias Welte (Hannover , Germany)

8:00 - 8:15 - What is the current global situation? Ann Versporten (Antwerp, Belgium)

8:15 - 8:30 - Resistance to antibiotics and antiseptics: same battle?


8:30 - 8:45 - Does resistance increase mortality or only complicate treatment? Michael S Niederman (New York, United States)

8:45 - 9:00 - How to manage KPC infections


9:00 - 9:15 - How to manage other carbapenemase-producing bacteria Jean-François Timsit (Paris, France)


9:30 - 9:45 - Should we cover ESBL only in colonized patients?


9:45 - 10:00 - New therapies for Gram–negative infections Thierry Calandra (Lausanne , Switzerland)

10:00 - 10:15 - Is phage therapy a great option?

Yok-Ai Que (Bern, Switzerland)

10:15 - 10:25 - Discussion

Fungal infections [Standard presentation] Moderator : Jean-Damien Ricard (Colombes, France) Moderator : Jean-François Timsit (Paris, France)

10:25 - 10:40 - Can fungi be responsible for sepsis? Thierry Calandra (Lausanne , Switzerland)

10:40 - 10:55 - New definitions


10:55 - 11:10 - Empirical antifungal therapy in the ICU: time to revisit Thierry Calandra (Lausanne , Switzerland)

11:10 - 11:20 - Discussion

11:20 - 11:35 - The use of beta-D-glucan to deescalate anti-fungal therapy?


11:35 - 11:50 - Ten rules for an antifungal stewardship program Matteo Bassetti (Udine, Italy)

11:50 - 12:05 - Risk of invasive aspergillosis in patients with pneumonia


12:05 - 12:15 - Discussion

Thursday 21 March 2019 - PM ROOM : Silver Hall Neurological outcomes [Standard presentation] Moderator : Jan Claassen (New York , United States) Moderator : Hannah Wunsch (Toronto, Canada)

13:45 - 14:00 - Brain-computer interface tools in post–comatose patients Steven Laureys (Liège , Belgium)

14:00 - 14:15 - Traumatic brain disease is a chronic progressive disease


14:15 - 14:30 - Prognostication after cardiac arrest Jerry Nolan (Bath, United Kingdom)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Novel biomarkers for outcome prediction


15:00 - 15:15 - We could improve prognostication guidelines Fabio S. Taccone (Brussels , Belgium)

15:15 - 15:25 - Discussion

15:25 - 15:45 - Break

Limiting postanoxic brain injury [Standard presentation] Moderator : Nino Stocchetti (Milan , Italy) Moderator : Victoria McCredie (Toronto, Canada)

15:45 - 16:00 - Optimizing brain oxygenation is more than ventilation Markus Skrifvars (Helsinki, Finland)

16:00 - 16:15 - What other options are there?

Jonathan Elmer (Pittsburgh, United States)

16:15 - 16:30 - Animal studies of induced hypothermia Hans Friberg (Lund , Sweden)

16:30 - 16:45 - Discussion

16:45 - 17:00 - Targeted temperature management: a literature review


17:00 - 17:15 - Who should receive TTM? Markus Skrifvars (Helsinki, Finland)

17:15 - 17:30 - Does the method of cooling make a difference?

Fabio S. Taccone (Brussels , Belgium)

17:30 - 17:45 - Do we have drugs in the pipeline? Alain Cariou (Paris, France)

17:45 - 18:00 - Discussion

Thursday 21 March 2019 - AM ROOM : 100 Hall Risk factors for ARDS [Standard presentation] Moderator : Daniel Brodie (New York, United States) Moderator : John P Kress (Chicago, United States)

8:00 - 8:15 - Environmental risk factors Carolyn S Calfee (San Francisco , United States)

8:15 - 8:30 - Biofluid induced lung injury

Gianluigi Li Bassi (Barcelona, Spain)

8:30 - 8:45 - Gender has an impact on management and outcome John G Laffey (Galway, Ireland)


8:55 - 9:10 - Break

Mechanical power as a concept [Pro-con debate] Moderator : Michael R. Pinsky (Pittsburgh, United States)

9:10 - 9:20 - Essential John J Marini (St Paul, United States)

9:20 - 9:30 - Confusing and useless

Marcelo Amato (Sao Paulo , Brazil)


Towards precision in ARDS [Standard presentation] Moderator : Hannah Wunsch (Toronto, Canada) Moderator : Frédéric Michard (Lausanne, Switzerland)

9:45 - 10:00 - How to move towards precision medicine Matthieu Jabaudon (Clermont-Ferrand, France)

10:00 - 10:15 - Even diffuse alveolar damage is often absent in clinical ARDS

Nuala Meyer (Wynnewood, United States)

10:15 - 10:30 - From genomics to phenotypes Nuala Meyer (Wynnewood, United States)

10:30 - 10:45 - Biomarkers can help


10:45 - 11:00 - Discussion

11:00 - 11:15 - Identifying ARDS phenotypes Carolyn S Calfee (San Francisco , United States)

11:15 - 11:30 - New biological evidence from ex–vivo studies

Michael A Matthay (San Francisco, United States)

11:30 - 11:45 - It´s all about understanding the pathophysiology Geoffrey Bellingan (London, United Kingdom)

11:45 - 12:00 - Finding treatment-responsive ARDS: physiology or biomarkers?

B Taylor Thompson (Boston , United States)

12:00 - 12:15 - Discussion

Thursday 21 March 2019 - PM ROOM : 100 Hall Early mobilization and rehabilitation [Standard presentation] Moderator : E Wesley Ely (Nashville, United States) Moderator : Elizabeth Wilcox (Toronto, Canada)

13:45 - 14:00 - Let us start with inspiratory muscle training Frank van Haren (Canberra, Australia)

14:00 - 14:15 - ICU-acquired weakness: preventable or inevitable?


14:15 - 14:30 - Implications of frailty and aging Zudin Puthucheary (London, United Kingdom)

14:30 - 14:45 - Discussion

14:45 - 15:00 - How to get children moving Karen Choong (Hamilton, Canada)

15:00 - 15:15 - How to keep elderly moving

Lauren Ferrante (New Haven, United States)

15:15 - 15:30 - A must before lung transplantation Diederik Gommers (Rotterdam, Netherlands)

15:30 - 15:45 - Discussion

15:45 - 16:00 - Early mobilization during ECMO: do we have data?


16:00 - 16:15 - We need concurrent nutritional support Thomas Lescot (Paris, France)

16:15 - 16:30 - We could do so much better!


16:30 - 16:45 - Discussion

16:45 - 17:00 - Break

Cardiac assistance [Standard presentation] Moderator : Ludhmila Hajjar (Sao Paulo, Brazil) Moderator : Heinrich Groesdonk (Homburg / Saar, Germany)

17:00 - 17:15 - There is no longer a role for the intraaortic balloon pump Holger Thiele (Leipzig, Germany)

17:15 - 17:30 - There is still a role for the intraaortic balloon pump


17:30 - 17:45 - The place of VA-ECMO Alain Combes (Paris , France)

17:45 - 18:00 - Discussion

Thursday 21 March 2019 - AM ROOM : Terarken (Bozar) Old and new adjunct therapies in ARDS [Standard presentation] Moderator : Jean-Paul Mira (Paris, France)

8:00 - 8:15 - Current pharmacological treatment of ARDS Marco V Ranieri (Bologna, Italy)

8:15 - 8:30 - We are underusing corticosteroids


8:30 - 8:45 - We are overusing corticosteroids B Taylor Thompson (Boston , United States)


9:00 - 9:15 - Interferon-beta in ARDS Geoffrey Bellingan (London, United Kingdom)

9:15 - 9:30 - Interference by corticosteroids on interferon–beta

Alain Mercat (Angers , France)

9:30 - 9:45 - Prevention by targeting platelets: beyond LIPS–A B Taylor Thompson (Boston , United States)

9:45 - 10:00 - Cell-based therapies


10:00 - 10:15 - Discussion

10:15 - 10:35 - Break

Who (not) to admit to ICU [Standard presentation] Moderator : J Randall Curtis (Seattle, United States) Moderator : Douglas White (Pittsburgh, United States)

10:35 - 10:50 - Physiological reserve: frailty vs comorbidities Maurizio Cecconi (Rozzano, MI, Italy)

10:50 - 11:05 - Which cancer patient?

Ludhmila Hajjar (Sao Paulo, Brazil)

11:05 - 11:20 - Which postoperative patient? Fabio Guarracino (Pisa, Italy)

11:20 - 11:35 - Discussion

11:35 - 11:50 - Who is too frail to be admitted?

Zudin Puthucheary (London, United Kingdom)

11:50 - 12:05 - We could offer a time-limited trial Jan Bakker (New York, United States)

12:05 - 12:15 - Discussion

Thursday 21 March 2019 - PM ROOM : Terarken (Bozar) How much protein? [Standard presentation] Moderator : Mette M Berger (Lausanne , Switzerland) Moderator : Karin Amrein (Graz , Austria)

13:45 - 14:00 - One size does not fit all Heleen Oudemans-Van Straaten (Amsterdam , Netherlands)

14:00 - 14:15 - Protein needs depend on timing

Pierre Singer (Petah Tikva , Israel)

14:15 - 14:30 - How to reach protein targets without overfeeding Arthur van Zanten (Ede, Netherlands)

14:30 - 14:40 - Discussion

14:40 - 14:55 - Glutamine supplementation


14:55 - 15:10 - Glutamine supplementation: resolving controversy Paul Wischmeyer (Durham, United States)

15:10 - 15:25 - Arginine replacement therapy

Juan B. Ochoa (Danville, United States)

15:25 - 15:35 - Discussion

15:35 - 15:50 - Break

Micronutrients and vitamins [Standard presentation] Moderator : Carole Ichai (Nice, France) Moderator : Juan B. Ochoa (Danville, United States)

15:50 - 16:05 - Enteral fish oil Arthur van Zanten (Ede, Netherlands)

16:05 - 16:20 - Unexpected micronutrient abnormalities in prolonged critical illness

Michaël Casaer (Leuven, Belgium)

16:20 - 16:35 - Micronutrient supplementation Michael Chourdakis (Thessaloniki, Greece)

16:35 - 16:45 - Discussion

16:45 - 17:00 - Vitamin D


17:00 - 17:15 - Vitamin C: the rationale Heleen Oudemans-Van Straaten (Amsterdam , Netherlands)

17:15 - 17:30 - Ready for vitamin C administration?

Laurence Busse (Atlanta, United States)

17:30 - 17:45 - Thiamine in sepsis Michael W Donnino (Boston, United States)

17:45 - 18:00 - Discussion

Thursday 21 March 2019 - AM ROOM : 400 Hall Feeding: how much is enough? [Standard presentation] Moderator : Michael Chourdakis (Thessaloniki, Greece) Moderator : Pierre Singer (Petah Tikva , Israel)

8:00 - 8:15 - Feeding the septic child Koen Joosten (Rotterdam , Netherlands)

8:15 - 8:30 - Early parenteral nutrition in children is also harmful

Greet Van den Berghe (Leuven , Belgium)

8:30 - 8:45 - Feeding the obese critically ill patient Marianne Chapman (Adelaide , Australia)


9:00 - 9:15 - Early metabolic effects of hypocaloric hyperproteic nutrition

Juan B. Ochoa (Danville, United States)

9:15 - 9:30 - What is the TARGET? Marianne Chapman (Adelaide , Australia)

9:30 - 9:45 - What should be the outcome of nutrition RCTs?



10:00 - 10:15 - Importance of timing calorie administration Arthur van Zanten (Ede, Netherlands)

10:15 - 10:30 - When to switch from less to more in nutrition therapy

Michaël Casaer (Leuven, Belgium)

10:30 - 10:45 - Insulin resistance could be a guide Jean-Charles Preiser (Brussels , Belgium)

10:45 - 11:00 - Discussion

11:00 - 11:15 - Break

ECMO should be available in every single ICU [Pro-con debate] Moderator : Markus Skrifvars (Helsinki, Finland)

11:15 - 11:45 - ECMO should be available in every ICU CON Alain Combes (Paris , France)

PRO Andreas Faltlhauser (Weiden in der Oberpfalz, Germany)

Challenges to antibiotic stewardship [Plenary lecture] 11:45 - 12:10 - Challenges to antibiotic stewardship

Michael Pulia (Madison, United States)

Thursday 21 March 2019 - PM ROOM : 400 Hall Satisfaction of relatives [Standard presentation] Moderator : Elie Azoulay (Paris , France) Moderator : Tom Schepens (Edegem, Belgium)

13:45 - 14:00 - The ICU should be wide open Jean-Paul Mira (Paris, France)

14:00 - 14:15 - How I conduct family conferences

J Randall Curtis (Seattle, United States)

14:15 - 14:30 - When the family just doesn´t get it Douglas White (Pittsburgh, United States)

14:30 - 14:45 - A decision making aid

Victoria Metaxa (London, United Kingdom)

14:45 - 14:55 - Discussion

Diagnostic tools in infection and sepsis [Standard presentation] Moderator : Thierry Calandra (Lausanne , Switzerland) Moderator : Jan Bakker (New York, United States)

14:55 - 15:10 - Progress in early pathogen identification and characterization Jean-Paul Mira (Paris, France)

15:10 - 15:25 - Next generation sequencing in clinical microbiology

Alex van Belkum (La Balme Les Grottes, France)

15:25 - 15:40 - Biomarker development Hector R Wong (Cincinnati , United States)

15:40 - 15:55 - Neutrophil protease storm in septic shock


15:55 - 16:10 - Assessing neutrophil responses Michael A Matthay (San Francisco, United States)

16:10 - 16:25 - Discussion

16:25 - 16:40 - Biomarkers in sepsis: what should we looking for?

Pietro Caironi (Turin, Italy)

16:40 - 16:55 - Biomarkers in sepsis: clinical utility Greg Martin (Atlanta, United States)

16:55 - 17:05 - Discussion

17:05 - 17:20 - Can biomarkers help to identify the patient at risk of sepsis?


17:20 - 17:35 - They can help to detect kidney failure in sepsis John Kellum (Pittsburgh, United States)

17:35 - 17:50 - How ´´omics´´ will change our lives

Benjamin Tang (Sydney, Australia)

17:50 - 18:00 - Discussion

Thursday 21 March 2019 - AM ROOM : Panoramic Hall Hematological challenges [Standard presentation] Moderator : David Boldt (Los Angeles, United States) Moderator : Tina Palmieri (Sacramento, United States)

8:00 - 8:15 - Sepsis in the neutropenic patient Thierry Calandra (Lausanne , Switzerland)

8:15 - 8:30 - Sepsis and thrombotic microangiopathy

Fiorella Paladino (Naples, Italy)

8:30 - 8:45 - Diagnosing thrombotic microangiopathies Beverley Hunt (London , United Kingdom)


9:00 - 9:15 - Treating thrombotic microangiopathies

Elie Azoulay (Paris , France)

9:15 - 9:30 - The role of the ICU physician in the management of acute TTP Tina Dutt (Liverpool, United Kingdom)

9:30 - 9:45 - Hemato–oncologic emergencies

Laveena Munshi (Toronto, Canada)

9:45 - 10:00 - Complications of new therapies for lymphomas Victoria Metaxa (London, United Kingdom)

10:00 - 10:15 - Discussion

10:15 - 10:35 - Break

Airway pressure-release ventilation [Pro-con debate] Moderator : Carlos Ferrando (Barcelona, Spain)

10:35 - 11:05 - Airway pressure release ventilation PRO Edward Litton (Perth, Australia)

CON John J Marini (St Paul, United States)

Aspiration pneumonia [Tutorial] 11:10 - 11:40 - Aspiration pneumonia


Hypoxemic acute respiratory failure - ARDS by another name? [Pro-con debate] Moderator : Steven Simpson (Kansas City, United States)

11:45 - 12:15 - Hypoxemic acute respiratory failure: ARDS by another name? CON Carolyn S Calfee (San Francisco , United States)

PRO Niall Ferguson (Toronto , Canada)

Thursday 21 March 2019 - PM ROOM : Panoramic Hall Stroke [Tutorial]

13:45 - 14:15 - Stroke Giuseppe Citerio (Monza, Italy)

Status epilepticus [Tutorial]

14:20 - 14:50 - Status epilepticus Raimund Helbok (Innsbruck, Austria)

Airway management [Tutorial]

14:55 - 15:25 - Airway management Samir Jaber (Montpellier, France)

How wrong ventilatory conditions impact the circulation [Tutorial]

15:30 - 16:00 - How wrong ventilatory conditions impact the circulation Michael R. Pinsky (Pittsburgh, United States)

Liberal vs restrictive fluid administration: what do you mean? [Standard presentation] Moderator : John Simpson (Newcastle upon Tyne, United Kingdom) Moderator : Antoine Schneider (Lausanne, Switzerland)

16:05 - 16:20 - The basis for (aggressive) fluid therapy Pietro Caironi (Turin, Italy)

16:20 - 16:35 - Liberal vs. restrictive fluid resuscitation

Nathan Shapiro (Boston , United States)

16:35 - 16:50 - Fluid resuscitation in septic shock: mechanisms of potential harm Frank van Haren (Canberra, Australia)

16:50 - 17:05 - When and how to deescalate fluid therapy?

Manu Malbrain (Brussels, Belgium)

17:05 - 17:20 - Discussion

Continuous renal replacement therapy [Tutorial] 17:25 - 18:00 - Continuous renal replacement therapy


Thursday 21 March 2019 - AM ROOM : Studio Room Ultrasound [Standard presentation] Moderator : Wesley Self (Nashville, United States) Moderator : Michel Slama (Amiens , France)

8:00 - 8:15 - Optimal training for basic and advanced echo Paul H Mayo (New Hyde Park, United States)

8:15 - 8:30 - Focused transthoracic echo

Heinrich Groesdonk (Homburg / Saar, Germany)

8:30 - 8:45 - To describe lung morphology in ARDS Davide Chiumello (Milan , Italy)


9:00 - 9:15 - To monitor ventilated patients

Francesco Mojoli (Pavia, Italy)

9:15 - 9:30 - To monitor the kidneys Antoine Schneider (Lausanne, Switzerland)

9:30 - 9:45 - To monitor the brain



10:00 - 10:15 - Break

Resuscitation end-points [Standard presentation] Moderator : Laurence Busse (Atlanta, United States) Moderator : Alain Cariou (Paris, France)

10:15 - 10:30 - Which hemodynamic parameter? Zsolt Molnar (Szeged , Hungary)

10:30 - 10:45 - Peripheral perfusion?

Jan Bakker (New York, United States)

10:45 - 11:00 - The microcirculation? Jacques Duranteau (Le Kremlin-Bicêtre , France)

11:00 - 11:15 - ScvO2 and the CO2-gap

Zsolt Molnar (Szeged , Hungary)

11:15 - 11:30 - Discussion

11:30 - 11:45 - We should not abandon ScvO2 monitoring Pietro Caironi (Turin, Italy)

11:45 - 12:00 - We should use the PCO2 gap in shock states


12:00 - 12:15 - Also monitor intraorgan PCO2? Tor Inge Tonnessen (Oslo , Norway)

12:15 - 12:30 - Discussion

Thursday 21 March 2019 - PM ROOM : Studio Room SvO2 measurements are useful [Pro-con debate] Moderator : Zsolt Molnar (Szeged , Hungary)

13:30 - 14:00 - SvO2 measurements are useful PRO Xavier Monnet (Le Kremlin-Bicêtre , France)

CON Antoine Vieillard-Baron (Boulogne-Billancourt , France)

Right ventricular failure [Tutorial] 14:05 - 14:35 - Right ventricular failure

Sven-Erik Ricksten (Gothenburg, Sweden)

Vasculitis in the ICU [Tutorial] 14:40 - 15:10 - Vasculitis in the ICU


Lung recruitment [Standard presentation] Moderator : Laurent Brochard (Toronto, Canada) Moderator : Dean R Hess (Danvers, United States)

15:15 - 15:30 - When and how? Niall Ferguson (Toronto , Canada)

15:30 - 15:45 - Hemodynamic effects


15:45 - 16:00 - When to recruit high-risk surgical patients Carlos Ferrando (Barcelona, Spain)

16:00 - 16:15 - Discussion

16:15 - 16:30 - It doesn´t improve outcome but who cares?

Zsolt Molnar (Szeged , Hungary)

16:30 - 16:45 - We should improve our practice Robert M Kacmarek (Boston, United States)

16:45 - 16:55 - Discussion

Echo-Doppler for initial evaluation [Tutorial]

17:00 - 17:30 - Echo-Doppler for initial evaluation Anthony McLean (Sydney , Australia)

Management of brain injury [Tutorial]

17:30 - 18:00 - Management of brain injury Mauro Oddo (Lausanne , Switzerland)

Thursday 21 March 2019 - AM ROOM : Corner A

Thursday 21 March 2019 - PM ROOM : Corner A ECMO [Meet the experts]

16:00 - 16:25 - ECMO Daniel De Backer (Brussels, Belgium), Alain Combes (Paris , France)

Hematological issues [Meet the experts]

16:30 - 17:00 - Hematological issues Jerrold H Levy (Durham, United States), Beverley Hunt (London , United Kingdom)

Thursday 21 March 2019 - AM ROOM : Corner B

Friday 22 March 2019 - AM ROOM : HLB Room

Friday 22 March 2019 - AM ROOM : Gold Hall RRT: practical aspects [Standard presentation] Moderator : Thomas Lescot (Paris, France) Moderator : Peter Pickkers (Nijmegen, Netherlands)

8:00 - 8:15 - What we currently do in France Carole Ichai (Nice, France)

8:15 - 8:30 - Avoiding dialytrauma

Detlef Kindgen-Milles (Düsseldorf , Germany)

8:30 - 8:45 - Optimal dosing Torsten Slowinski (Berlin, Germany)


8:55 - 9:10 - Higher rates in sepsis?

Stephane Gaudry (Colombes, France)

9:10 - 9:25 - Citrate and acid–base balance Carole Ichai (Nice, France)

9:25 - 9:40 - Complications of citrate: accumulation vs intoxication



9:50 - 10:05 - No need for calcium–free solutions Ravindra Mehta (La Jolla, United States)

10:05 - 10:20 - Do not feed the filter! Dietary adaptations

Elisabeth De Waele (Brussels, Belgium)

10:20 - 10:35 - Nutritional management Marianne Chapman (Adelaide , Australia)

10:35 - 10:50 - How to adapt antibiotic and antifungal treatments

Patrick Honoré (Bruxelles, Belgium)

10:50 - 11:05 - Discussion

Vasoactive agents [Standard presentation] Moderator : Jan Bakker (New York, United States) Moderator : Michael Sander (Giessen, Germany)

11:05 - 11:20 - Rational use of vasopressors Heinrich Groesdonk (Homburg / Saar, Germany)

11:20 - 11:35 - Inodilators in the ICU

Antoine Herpain (Brussels, Belgium)

11:35 - 11:50 - Renal effects Sven-Erik Ricksten (Gothenburg, Sweden)

11:50 - 12:05 - Short vs. long-term effects


12:05 - 12:20 - Immunomodulating effects Peter Pickkers (Nijmegen, Netherlands)

12:20 - 12:35 - Discussion

Friday 22 March 2019 - PM ROOM : Gold Hall Pancreatitis [Tutorial]

13:30 - 14:00 - Pancreatitis Pierre-François Laterre (Brussels , Belgium)

Assisted breathing [Standard presentation] Moderator : Davide Chiumello (Milan , Italy) Moderator : Dean R Hess (Danvers, United States)

14:05 - 14:20 - The different modes Dean R Hess (Danvers, United States)

14:20 - 14:35 - Monitoring and improving diaphragm function

Niall Ferguson (Toronto , Canada)

14:35 - 14:50 - Do respiratory muscles work during mechanical ventilation? Laurent Brochard (Toronto, Canada)

14:50 - 15:05 - Discussion

15:05 - 15:20 - Neurally-adjusted ventilatory assist

Philip Hopkins (London, United Kingdom)

15:20 - 15:35 - Measuring compliance and driving pressure in spontaneous breathing Giacomo Bellani (Monza, Italy)

15:35 - 15:50 - How to estimate the “muscle–driving–pressure”

Marcelo Amato (Sao Paulo , Brazil)

15:50 - 16:05 - Diaphragm atrophy: what adults can learn from kids Tom Schepens (Edegem, Belgium)

16:05 - 16:20 - Discussion

Friday 22 March 2019 - AM ROOM : Copper Hall ECMO for respiratory failure [Standard presentation] Moderator : Laurent Brochard (Toronto, Canada) Moderator : Alain Combes (Paris , France)

8:00 - 8:15 - A short history Michael Quintel (Göttingen , Germany)

8:15 - 8:30 - Natural lung gas exchange during ECMO


8:30 - 8:45 - Ventilator settings: rest the lungs Lars Broman (Stockholm, Sweden)

8:45 - 9:00 - Ventilator settings: keep the lung open



9:15 - 9:30 - To rest or to recruit? Niall Ferguson (Toronto , Canada)

9:30 - 9:45 - Should we use prone positioning in ECMO patients?


9:45 - 10:00 - Functional trajectories of recovery Antonio Pesenti (Milan , Italy)

10:00 - 10:10 - Discussion

10:10 - 10:30 - Break

ECMO: practical aspects [Standard presentation] Moderator : Tor Inge Tonnessen (Oslo , Norway) Moderator : Denise Veelo (Amsterdam , Netherlands)

10:30 - 10:45 - Problems of cannula design and configuration Lars Broman (Stockholm, Sweden)

10:45 - 11:00 - Percutaneous vs. surgical VA-ECMO cannulation


11:00 - 11:15 - Managing the hemostatic consequences Beverley Hunt (London , United Kingdom)

11:15 - 11:30 - Discussion

11:30 - 11:45 - Persisting hypoxemia on VV–ECMO


11:45 - 12:00 - Weaning from ECMO Antonio Pesenti (Milan , Italy)

12:00 - 12:15 - Withdrawing life support: how it´s different and how it´s the same?

J Randall Curtis (Seattle, United States)

12:15 - 12:30 - Discussion

Friday 22 March 2019 - PM ROOM : Copper Hall Neurologic challenges [Standard presentation] Moderator : David Menon (Cambridge , United Kingdom) Moderator : Geert Meyfroidt (Leuven , Belgium)

13:30 - 13:45 - Neurological evaluation in complex conditions Nino Stocchetti (Milan , Italy)

13:45 - 14:00 - Shaking in the ICU

Marek Mirski (Baltimore, United States)

14:00 - 14:15 - Vasospasm in subarachnoid hemorrhage Raimund Helbok (Innsbruck, Austria)

14:15 - 14:30 - Discussion

14:30 - 14:45 - Treatment of super-refractory status epilepticus

Jan Claassen (New York , United States)

14:45 - 15:00 - Disorders of consciousness: recent guidelines Steven Laureys (Liège , Belgium)

15:00 - 15:15 - Paroxysmal sympathetic hyperactivity


15:15 - 15:30 - Discussion

Friday 22 March 2019 - AM ROOM : Salle M (Bozar) Heparin induced thrombocytopenia [Tutorial]

8:00 - 8:30 - Heparin-induced thrombocytopenia Jerrold H Levy (Durham, United States)

Patient-ventilator asynchronies [Tutorial]

8:35 - 9:05 - Patient–ventilator asynchronies Alain Mercat (Angers , France)

Nutritional strategies [Tutorial]

9:10 - 9:40 - Nutritional strategies Mette M Berger (Lausanne , Switzerland)

9:40 - 10:00 - Break

Intracranial hypertension [Standard presentation] Moderator : Raimund Helbok (Innsbruck, Austria) Moderator : Jonathan Elmer (Pittsburgh, United States)

10:00 - 10:15 - Should we be prophylactic? Mauro Oddo (Lausanne , Switzerland)

10:15 - 10:30 - Still a place for osmotic therapy?

Giuseppe Citerio (Monza, Italy)

10:30 - 10:45 - The non–cerebral effects of hypertonic saline Marek Mirski (Baltimore, United States)

10:45 - 11:00 - Mannitol may alter renal function

Markus Skrifvars (Helsinki, Finland)

11:00 - 11:15 - Discussion

11:15 - 11:30 - What about hypertonic lactate? Carole Ichai (Nice, France)

11:30 - 11:45 - Temperature management


11:45 - 12:00 - Escalating therapies: when to start and how to do it Nino Stocchetti (Milan , Italy)

12:00 - 12:15 - Better patient selection for extreme therapies


12:15 - 12:30 - Discussion

Friday 22 March 2019 - AM ROOM : Tent Neuromonitoring [Standard presentation] Moderator : Steven Laureys (Liège , Belgium) Moderator : Jan Claassen (New York , United States)

8:00 - 8:15 - Expanding the use of EEG monitoring Jan Claassen (New York , United States)

8:15 - 8:30 - Cortical spreading depolarizations

Raimund Helbok (Innsbruck, Austria)

8:30 - 8:45 - How to assess cerebrovascular autoregulation Geert Meyfroidt (Leuven , Belgium)

8:45 - 9:00 - Brain tissue PO2 is better than ICP



9:15 - 9:30 - Pupillometry: what can we do with this? Fabio S. Taccone (Brussels , Belgium)

9:30 - 9:45 - Automated pupillometry for outcome prognostication in cardiac arrest


9:45 - 10:00 - Can we rely on minimally invasive techniques? Nino Stocchetti (Milan , Italy)

10:00 - 10:15 - Discussion

10:15 - 10:30 - Break

Endocrine emergencies [Tutorial]

10:30 - 11:00 - Endocrine emergencies Karin Amrein (Graz , Austria)

Palliative care in the ICU [Tutorial]

11:05 - 11:35 - Palliative care in the ICU J Randall Curtis (Seattle, United States)

Metabolic support (T) [Tutorial] 11:40 - 12:10 - Metabolic support


Preventing renal failure (T) [Tutorial] 12:15 - 12:45 - Preventing renal failure

Heleen Oudemans-Van Straaten (Amsterdam , Netherlands)

Friday 22 March 2019 - PM ROOM : Tent The gut [Standard presentation] Moderator : Mette M Berger (Lausanne , Switzerland) Moderator : Gianni Biancofiore (Pisa, Italy)

13:30 - 13:45 - Gut dysfunction during critical illness Marianne Chapman (Adelaide , Australia)

13:45 - 14:00 - Impaired gastrointestinal motility

Olivier Huet (Brest, France)

14:00 - 14:15 - Upper gastric tract endoscopy is often useless Jean-Damien Ricard (Colombes, France)

14:15 - 14:30 - Discussion

14:30 - 14:45 - Non–occlusive mesenteric ischemia

Heinrich Groesdonk (Homburg / Saar, Germany)

14:45 - 15:00 - Severe pancreatitis: when to give antibiotics? Pierre-François Laterre (Brussels , Belgium)

15:00 - 15:15 - Severe pancreatitis: minimal drainage


15:15 - 15:30 - Probiotics/synbiotics: for whom, when, and how do they work? Paul Wischmeyer (Durham, United States)

15:30 - 15:45 - Discussion

Friday 22 March 2019 - AM ROOM : Silver Hall How I see the future [Standard presentation] Moderator : Diederik Gommers (Rotterdam, Netherlands) Moderator : Hans Friberg (Lund , Sweden)

8:00 - 8:15 - Designing the future ICU Ricard Ferrer (Barcelona, Spain)

8:15 - 8:30 - How the ICU will be organized

Hannah Wunsch (Toronto, Canada)

8:30 - 8:45 - Who will be running the ICU? Jacques Creteur (Brussels , Belgium)

8:45 - 9:00 - Non-invasive cardiac imaging



9:15 - 9:30 - The ultimate patient monitor John Welch (London , United Kingdom)

9:30 - 9:45 - The future is non–invasive Thomas Scheeren (Groningen, Netherlands)

9:45 - 10:00 - ... or full of extracorporeal organ support


10:00 - 10:15 - Extracorporal lung assist will be used for COPD Tobias Welte (Hannover , Germany)

10:15 - 10:30 - Discussion

10:30 - 10:45 - ECOS will be a reality

Lui Forni (Guilford, United Kingdom)

10:45 - 11:00 - Concepts and technology of the ICU in vivo Can Ince (Amsterdam , Netherlands)

11:00 - 11:15 - Automatic, real–time systems will support clinical decision–making

Alexandre Joosten (Le Kremlin-Bicêtre, Belgium)

11:15 - 11:30 - Discussion

11:30 - 11:45 - Informatics everywhere Philip Hopkins (London, United Kingdom)

11:45 - 12:00 - Smartphone applications everywhere


12:00 - 12:15 - Precision medicine everywhere Benjamin Tang (Sydney, Australia)

12:15 - 12:30 - Discussion

Friday 22 March 2019 - PM ROOM : Silver Hall Lactate revisited [Standard presentation] Moderator : Ricard Ferrer (Barcelona, Spain)

13:30 - 13:45 - The biochemistry of hyperlactatemia Mervyn Singer (London, United Kingdom)

13:45 - 14:00 - Can we distinguish aerobic from anaerobic formation?

Tor Inge Tonnessen (Oslo , Norway)

14:00 - 14:15 - In sepsis Grant Bochicchio (St Louis, United States)

14:15 - 14:30 - In cirrhosis

Thierry Gustot (Brussels, Belgium)

14:30 - 14:45 - Discussion

14:45 - 15:00 - After cardiac surgery Lars Wiuff Andersen (Aarhus, Denmark)

15:00 - 15:15 - In renal replacement therapy


15:15 - 15:30 - In acute brain injury Mauro Oddo (Lausanne , Switzerland)

15:30 - 15:45 - How can it ´´guide´´ resuscitation?

Jan Bakker (New York, United States)

15:45 - 16:00 - Lactate is a friend Lui Forni (Guilford, United Kingdom)

16:00 - 16:15 - Discussion

Friday 22 March 2019 - AM ROOM : 100 Hall Long term outcomes [Standard presentation] Moderator : Victoria Metaxa (London, United Kingdom) Moderator : Karen Choong (Hamilton, Canada)

8:00 - 8:15 - Understanding trajectories of critical illness John Prowle (London, United Kingdom)

8:15 - 8:30 - Chronic critical illness

Zudin Puthucheary (London, United Kingdom)

8:30 - 8:45 - Recovery after critical illness: the patient´s perspective Timothy Walsh (Edinburgh , United Kingdom)

8:45 - 9:00 - Healthcare resource use and associated costs in the first three years



9:15 - 9:30 - How ARDS management can influence quality of life Christian Karagiannidis (Cologne, Germany)

9:30 - 9:45 - Bone during and after ICU


9:45 - 10:00 - Functional outcomes in older ICU survivors Lauren Ferrante (New Haven, United States)

10:00 - 10:15 - Outcomes of elderly ICU patients

Frank van Haren (Canberra, Australia)

10:15 - 10:30 - Discussion

10:30 - 10:45 - Cognitive outcomes Elizabeth Wilcox (Toronto, Canada)

10:45 - 11:00 - Acquired dementia E Wesley Ely (Nashville, United States)

11:00 - 11:15 - How we will improve prognostication after traumatic brain injury


11:15 - 11:30 - Discussion

11:30 - 11:45 - Impact of income on outcomes John G Laffey (Galway, Ireland)

11:45 - 12:00 - Do we need after–ICU care services?

Elizabeth Wilcox (Toronto, Canada)

12:00 - 12:15 - The role of the general practitioner in follow–up Jean-Charles Preiser (Brussels , Belgium)

12:15 - 12:30 - Discussion

Friday 22 March 2019 - PM ROOM : 100 Hall Transfusion strategies [Standard presentation] Moderator : Christian Karagiannidis (Cologne, Germany) Moderator : Elisabeth De Waele (Brussels, Belgium)

13:30 - 13:45 - How to treat anemic patients before surgery Michael Sander (Giessen, Germany)

13:45 - 14:00 - Strategies in surgical patients

Ludhmila Hajjar (Sao Paulo, Brazil)

14:00 - 14:15 - Strategies in burn injury Tina Palmieri (Sacramento, United States)

14:15 - 14:30 - Strategies in head injury


14:30 - 14:45 - Discussion

14:45 - 15:00 - Transfusion-associated circulatory overload (TACO): a problem in the ICU? Denise Veelo (Amsterdam , Netherlands)

15:00 - 15:15 - When should we give iron?

Edward Litton (Perth, Australia)

15:15 - 15:30 - Transferrin as a therapy for anemia of inflammation Nicole Juffermans (Amsterdam , Netherlands)

15:30 - 15:45 - We need hemoglobin solutions

Can Ince (Amsterdam , Netherlands)

15:45 - 16:00 - Anemia after ICU discharge: does it matter? Timothy Walsh (Edinburgh , United Kingdom)

16:00 - 16:15 - Discussion

Friday 22 March 2019 - AM ROOM : Terarken (Bozar) Acute-on-chronic liver failure [Standard presentation] Moderator : Stephan Jakob (Bern, Switzerland) Moderator : Grant Bochicchio (St Louis, United States)

8:00 - 8:15 - What is this exactly? Thierry Gustot (Brussels, Belgium)

8:15 - 8:30 - Infectious complications


8:30 - 8:45 - Hepato–renal syndrome Pierre-François Laterre (Brussels , Belgium)

8:45 - 9:00 - Cirrhotic coagulopathy: facts and myths

Gianni Biancofiore (Pisa, Italy)


9:15 - 9:30 - Update on blood detoxification Patrick Honoré (Bruxelles, Belgium)

9:30 - 9:45 - Long-term outcomes for patients with alcoholic liver disease


9:45 - 10:00 - Liver transplantation: indications and limits Thierry Gustot (Brussels, Belgium)

10:00 - 10:15 - Discussion

Avoiding the next negative RCT? [Standard presentation] Moderator : Mervyn Singer (London, United Kingdom) Moderator : Djillali Annane (Garches , France)

10:15 - 10:30 - Time to pause RCTs in CCM? Brian Kavanagh (Toronto, Canada)

10:30 - 10:45 - There is still a place for pathophysiological studies

Nino Stocchetti (Milan , Italy)

10:45 - 11:00 - Limitations of a usual care arm in clinical research B Taylor Thompson (Boston , United States)

11:00 - 11:15 - What about Bayesian statistics


11:15 - 11:30 - Discussion

11:30 - 11:45 - Adjusting for pre–illness health status is vital Timothy Walsh (Edinburgh , United Kingdom)

11:45 - 12:00 - End–of–life decisions are underreported


12:00 - 12:15 - Electronic medical record data can be informative Michelle N Gong (New York, United States)

12:15 - 12:30 - Patients are partners in ICU research

John C Marshall (Toronto , Canada)

12:30 - 12:45 - Discussion

Friday 22 March 2019 - AM ROOM : 400 Hall Better understanding of ARDS [Standard presentation] Moderator : Marcelo Amato (Sao Paulo , Brazil) Moderator : Giacomo Bellani (Monza, Italy)

8:00 - 8:15 - Pulmonary and extrapulmonary ARDS: are they different? Davide Chiumello (Milan , Italy)

8:15 - 8:30 - Re-classification of ARDS severity: does it help?

John G Laffey (Galway, Ireland)

8:30 - 8:45 - Are biomarkers of any value? Laurent Papazian (Marseille , France)


9:00 - 9:15 - An updated acute lung injury score


9:15 - 9:30 - Beware of ARDS mimickers Elie Azoulay (Paris , France)

9:30 - 9:45 - Pulmonary fibrosis is a different disease



Vasopressor agents [Standard presentation] Moderator : Michael W Donnino (Boston, United States) Moderator : Edward Litton (Perth, Australia)

10:00 - 10:15 - The burden of shock Laurence Busse (Atlanta, United States)

10:15 - 10:30 - Why hypotension matters

Thomas Scheeren (Groningen, Netherlands)

10:30 - 10:45 - Vasopressin in vasodilatory shock Ludhmila Hajjar (Sao Paulo, Brazil)

10:45 - 11:00 - How I use vasopressors early in septic shock


11:00 - 11:15 - Discussion

11:15 - 11:30 - Angiotensin II in vasodilatory shock David Boldt (Los Angeles, United States)

11:30 - 11:45 - Love a good blood pressure... but don’t forget the heart!


11:45 - 12:00 - Are we ready for closed–loop systems? Alexandre Joosten (Le Kremlin-Bicêtre, Belgium)

12:00 - 12:15 - Discussion

Friday 22 March 2019 - PM ROOM : 400 Hall Iatrogenic problems/issues [Standard presentation] Moderator : Frank van Haren (Canberra, Australia) Moderator : Stephan Jakob (Bern, Switzerland)

13:30 - 13:45 - Alarms should be optimized Diederik Gommers (Rotterdam, Netherlands)

13:45 - 14:00 - There is too much noise in your ICU


14:00 - 14:15 - Many patients are still oversedated E Wesley Ely (Nashville, United States)

14:15 - 14:30 - Discussion

14:30 - 14:45 - Iatrogenic air embolism


14:45 - 15:00 - Changing the PICU paradigm: from a toxic to a healing environment Karen Choong (Hamilton, Canada)

15:00 - 15:15 - Hyponatremia is often iatrogenic

Stephan Jakob (Bern, Switzerland)

15:15 - 15:30 - Discussion

Friday 22 March 2019 - AM ROOM : Panoramic Hall How I measure abdominal pressure [Tutorial]

8:00 - 8:35 - How I measure abdominal pressure Manu Malbrain (Brussels, Belgium)

Cardiogenic shock [Tutorial]

8:40 - 9:15 - Cardiogenic shock Holger Thiele (Leipzig, Germany)

Passive leg raising [Tutorial]

9:20 - 9:55 - Passive leg raising Xavier Monnet (Le Kremlin-Bicêtre , France)

Improving communication with the relatives [Tutorial]

10:00 - 10:35 - Improving communication with the relatives Douglas White (Pittsburgh, United States)

Pneumonia in the immunocompromised [Tutorial]

10:40 - 11:15 - Pneumonia in the immunocompromised Elie Azoulay (Paris , France)

ECCO2 R [Tutorial]

11:20 - 11:55 - ECCO2R Christian Karagiannidis (Cologne, Germany)

Respiratory support in children [Tutorial]

12:00 - 12:30 - Respiratory support in children Tom Schepens (Edegem, Belgium)

Friday 22 March 2019 - PM ROOM : Panoramic Hall End-of-life issues [Standard presentation] Moderator : Lauren Ferrante (New Haven, United States) Moderator : Victoria Metaxa (London, United Kingdom)

13:30 - 13:45 - What is a ‘good death’ for the patient? Victoria Metaxa (London, United Kingdom)

13:45 - 14:00 - What is a ‘good death’ for relatives?


14:00 - 14:15 - Health system level interventions to increase goals–of–care discussions J Randall Curtis (Seattle, United States)

14:15 - 14:30 - Discussion

14:30 - 14:45 - Advance technologies create new ethical challenges

Victoria Metaxa (London, United Kingdom)

14:45 - 15:00 - No patient should die without ECMO, right? Daniel Brodie (New York, United States)

15:00 - 15:15 - We overuse antibiotics at the end of life


15:15 - 15:30 - Discussion

15:30 - 15:45 - Responding to requests for futile or inappropriate treatment Douglas White (Pittsburgh, United States)

15:45 - 16:00 - Do we need an external consult?

Michael Quintel (Göttingen , Germany)

16:00 - 16:15 - Discussion

Friday 22 March 2019 - AM ROOM : Studio Room HAP and VAP [Standard presentation] Moderator : Alex van Belkum (La Balme Les Grottes, France)

8:00 - 8:15 - Diagnosis of VAP: still a challenge John Simpson (Newcastle upon Tyne, United Kingdom)

8:15 - 8:30 - Prevention of VAP: have we made progress?

Gianluigi Li Bassi (Barcelona, Spain)

8:30 - 8:45 - HAP in non ventilated ICU–acquired pneumonia Jean-François Timsit (Paris, France)


9:00 - 9:15 - US vs. European approach


9:15 - 9:30 - Risk factors for MDR/XDR microorganisms Antoni Torres (Barcelona , Spain)


9:45 - 10:05 - Break

Severe CAP [Standard presentation] Moderator : Nicole Juffermans (Amsterdam , Netherlands) Moderator : Matteo Bassetti (Udine, Italy)

10:05 - 10:20 - Initial management Michael S Niederman (New York, United States)

10:20 - 10:35 - How biomarkers can help


10:35 - 10:50 - Pneumococcal pneumonia: who dies and when? Jean-Paul Mira (Paris, France)

10:50 - 11:05 - Discussion

11:05 - 11:20 - Lymphopenic CAP


11:20 - 11:35 - Adjunct therapies Antoni Torres (Barcelona , Spain)

11:35 - 11:50 - Discussion

Choosing the optimal ventilatory conditions [Tutorial]

11:55 - 12:30 - Choosing the optimal ventilatory conditions Dean R Hess (Danvers, United States)

Friday 22 March 2019 - AM ROOM : Corner A

Friday 22 March 2019 - AM ROOM : Corner B

Documents

Moderator : Opening - Intensive · Lars Wiuff Andersen (Aarhus, Denmark) 17:15 - 17:25 - Discussion ... Massimo Antonelli (Rome, Italy) 12:00 - 12:15 - Discussion . Tuesday 19 March