MÁLAGA 12th - 13th DECEMBER 2019...exclusively dedicated to the value of plasma in the CRC and new concepts in molecular biology in hepatocarcinoma and bile duct. The second day is

SEDE: HOTEL NH MÁLAGA

Organized by

Under the auspices of

Scientific and Sanitary Interest accredited by

Accredited by

Secretaría General de Investigación, Desarrollo e Innovación enSalud de la Consejería de Salud y Familias de la Junta de Andalucía

MÁLAGA 12th - 13th DECEMBER 201927 INTERNATIONALSYMPOSIUM

SCIENTIFIC PROGRAMADVANCES IN THE TREATMENT OF DIGESTIVE TUMOURS

27 INTERNATIONALSYMPOSIUM

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Dear friend, on behalf of the Spanish Cooperative Group for the Treatment of Digestive Tumors (TTD), we are pleased to invite you to the 27 International Symposium of our group, which will take place on December 12th and 13th in Malaga.

As in previous years, the objective of the symposium is the presentation and discussion of current issues in digestive cancer as well as the knowledge and research exchange that generates these type of events.

We have developed a program that includes a couple of round tables of controversies on the first day, a table exclusively dedicated to the value of plasma in the CRC and new concepts in molecular biology in hepatocarcinoma and bile duct. The second day is dedicated exclusively to the mCRC on highly topical issues such as immunotherapy, CTC with results of the VISNU study, ctDNA and sequence.

For this, we have an ambitious program full of great experts that will allow to give us an always enriching discussion.

For all this, it will be a pleasure to have your presence and active participation.

Organizig CommitteeMálaga, Spain

INTRODUCTION

ADVANCES IN THE TREATMENTOF DIGESTIVE TUMOURS

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ORGANIZING COMMITTEE: COORDINATORS

ORGANIZATION

Manuel Benavides Isabel Sevilla Silvia Gil Inmaculada Ales Esperanza Torres Gema Durán Mireia Cazorla Julia Alcaide Grupo Cáncer Digestivo. Hospital Regional Uni-versitario, Virgen de la Victoria and Costa del Sol, Málaga, Spain

ORGANIZING COMMITTEE: VOCALSEnrique Aranda Reina Sofía University Hospital Córdoba, Spain

Manuel BenavidesHospital Regional Universitario y Virgen de la VictoriaMálaga, Spain

Alfredo CarratoUniversity Hospital Ramón y Cajal Madrid, Spain

Eduardo Díaz-RubioSan Carlos Clinical University Hospital Madrid, Spain

Ana Fernández MontesUniversity Hospital Complex of Ourense Ourense, Spain

Pilar García Alfonso Gregorio Marañón University Hospital Madrid, Spain

Begoña GrañaHospital University Complex A Coruña, Spain

Cristina GrávalosUniversity Hospital 12 de Octubre Madrid, Spain

Jerónimo Jiménez CastroVirgen del Rocío University Hospital Seville, Spain

Paula Jiménez FonsecaCentral University Hospital of Asturias Oviedo, Spain

Carles PericaySabadell Hospital, Parc Tauli Health Corporation Sabadell, Spain

Fernando RiveraUniversity Hospital Marqués de Valdecilla Santander, Spain

Mª J. Safont University General Hospital Valencia, Spain

Ramón SalazarICO, Duran i Reynals Hospital Barcelona, Spain

Javier SastreSan Carlos Clinical University Hospital Madrid, Spain

Josep TaberneroUniversity Hospital Vall d’Hebrón Barcelona, Spain


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FACULTY

Alcaide, JuliaCosta del Sol Hospital Málaga, Spain

Andre, ThierryHôpital Saint-AntoineParis Cedex, France

Antón Torres, AntonioUniversity Hospital Miguel Servet Zaragoza, Spain

Aranda, EnriqueReina Sofía University Hospital Córdoba, Spain

Argilés, GuillémUniversity Hospital Vall d’Hebrón Barcelona, Spain

Carbonnel, FranckKremlin Bicêtre Hospital, University Paris Saclay, France

Carrato, AlfredoUniversity Hospital Ramón y Cajal Madrid, Spain

Cervantes, Andrés University Clinical Hospital of ValenciaValencia, Spain

del Valle, EmilioUniversity Hospital Gregorio Marañón Madrid, Spain

di Nicolantonio, FedericaUniversity of Torino, School of MedicineTurin, Italy

Díaz-Rubio, EduardoSan Carlos Clinical University HospitalMadrid, Spain

Dienstmann, RodrigoUniversity Hospital Vall d’Hebrón Barcelona, Spain

Élez, ElenaUniversity Hospital Vall d’HebrónBarcelona, Spain

Fernández Montes, AnaUniversity Hospital Complex of Ourense Ourense, Spain

Gallego, JavierUniversity General Hospital of ElcheAlicante, Spain

García Alfonso, PilarUniversity Hospital Gregorio MarañónMadrid, Spain

Gómez España, AuxiliadoraReina Sofía University Hospital Córdoba, Spain

González Flores, EncarnaciónVirgen de las Nieves University HospitalGranada, Spain

Graña, BegoñaHospital University ComplexA Coruña, Spain


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Grávalos Castro, CristinaUniversity Hospital 12 de Octubre Madrid, Spain

Jiménez Castro, Jerónimo Virgen del Rocío University Hospital Seville, Spain

Jiménez Fonseca, Paula Central University Hospital of Asturias Oviedo, Spain

López López, Carlos University Hospital Marqués de ValdecillaSantander, Spain

Macarulla, TeresaUniversity Hospital Vall d’HebrónBarcelona, Spain

Martinelli, ErikaDipartimento di Internistica Clinica e Sperimentale‘F Magrassi’. Nápoles, Italy

Montagut, ClaraHospital del MarBarcelona, Spain

Pericay, CarlesSabadell Hospital, Parc Tauli Health CorporationSabadell, Spain

Rivera Herrero, FernandoUniversity Hospital Marqués de Valdecilla Santander, Spain

Safont Aguilera, Mª JoséUniversity General HospitaoValencia, Spain

Salazar Soler, Ramón. ICO, Duran i Reynals HospitalBarcelona, Spain

Sastre Valera, JavierSan Carlos Clinical University Hospital Madrid, Spain

Tie, JeanneWalter and Eliza Hall Institute of Medical Research Melbourne, Australia

Valladares, ManuelReina Sofía University HospitalCórdoba, Spain


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SCIENTIFIC PROGRAM

WEDNESDAY, 11 DECEMBER 20:00-21:00 SATELLITE SYMPOSIUM. Sponsored by Merck.

THURSDAY, 12 DECEMBER 09:00-10:00 SATELLITE SYMPOSIUM. Sponsored by Lilly.

10:15-10:30 OPENING

1ST TABLE. BILE DUCT AND HEPATOCELLULAR CARCINOMA

Moderators: J. Sastre (San Carlos Clinical University Hospital, Madrid. Spain). C. Grávalos (University Hospital 12 de Octubre, Madrid. Spain).

10:30-10:50 Molecular outlook in bile duct cancer. A. Fernández Montes (University Hospital Complex of Ourense. Spain).

10:50-11:10 New targets in the bile duct: results. T. Macarulla (University Hospital Vall d’Hebrón, Barcelona. Spain).

11:10-11:30 Molecular outlook in hepatocellular carcinoma. C. López (University Hospital Marqués de Valdecilla, Santander, Spain).

11:30-11:50 Immunotherapy in hepatocellular carcinoma. J. Jiménez Castro (Virgen del Rocío University Hospital, Seville. Spain). 11:50-12:20 Discussion.

12:20-12:50 Coffee.

2ND TABLE. CONTROVERSIES IN GASTROINTESTINAL CANCER Moderators: B. Graña (Hospital University Complex, A Coruña. Spain). E. González Flores (Virgen de las Nieves University Hospital, Granada. Spain).

12:50-13:10 Resectable pancreatic cancer: Best strategy. J. Gallego (University General Hospital of Elche, Alicante. Spain).


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13:10-13:30 HIPEC in colorectal cancer: perspective of the medical oncologist. J. Alcaide (Costa del Sol Hospital, Málaga. Spain).

13:30-13:50 Immunotherapy in advanced esophagogastric gastric cancer: selection criteria. P. Jiménez Fonseca (Central University Hospital of Asturias, Oviedo. Spain).

13:50-14:20 Discussion.

14:20-14:35 Resolution of clinical cases competition and presentation of the winning case.

14:35-16:00 Satellite symposium-lunch. Sponsored by Servier, or

14:35-16:00 Lunch.

3RD TABLE. THE IMPORTANCE OF PLASMA IN COLORECTAL CANCER

Moderators: R. Salazar (ICO. Duran i Reynals Hospital, Barcelona. Spain). F. Rivera (University Hospital Marqués de Valdecilla, Santander. Spain).

16:00-16:20 ESMO Scale for Clinical Actionability of Molecular Targets (ESCAT). R. Dienstmann (University Hospital Vall d’Hebrón, Barcelona. Spain).

16:20-16:40 Platforms and genes: which ones for metastatic colorectal cancer. C. Montagut (Hospital del Mar, Barcelona. Spain).

16:40-17:00 MSI, immunoscore, ctDNA: an opportunity for adjuvancy in localized colon cancer. J. Tie (Walter and Eliza Hall Institute of Medical Research, Melbourne. Australia).


17:30-18:00 Coffee.


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SCIENTIFIC PROGRAM

4TH TABLE. SHIFTING THE PARADIGM IN T3-T4 OR N+ RECTAL CANCER

Moderators: C. Pericay (Sabadell Hospital, Parc Tauli Health Corporation, Sabadell. Spain). Mª J. Safont (University General Hospital, Valencia. Spain).

18:00-18:05 Introduction and first vote.

18:05-18:20 In favour of the standard. A. Gómez España (Reina Sofía University Hospital, Córdoba. Spain).

18:20-18:35 In favour of total neoadjuvant treatment. A. Cervantes (University Clinical Hospital of Valencia, Valencia. Spain).

18:35-18:40 Second vote.

18:40-18:55 Surgery. E. del Valle (University Hospital Gregorio Marañón, Madrid. Spain).



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FRIDAY, DECEMBER 13 09:00-10:00 SATELLITE SYMPOSIUM. Sponsored by Amgen.

5TH TABLE. IMMUNOTHERAPY IN METASTATIC COLORECTAL CANCER

Moderators: A. Carrato (University Hospital Ramón y Cajal, Madrid. Spain). A. Antón (University Hospital Miguel Servet, Zaragoza. Spain).

10:15-10:35 Biomarkers for immunotherapy in the selection of metastatic colorectal cancer patients: Beyond MSI. M. Valladares (Reina Sofía University Hospital, Córdoba. Spain).

10:35-10:55 Immunotherapy in MSS metastatic colorectal cancer: Beyond the checkpoints inhibitors, clinical results. G. Argilés (University Hospital Vall d’Hebrón, Barcelona. Spain).

10:55-11:15 Treatment of patients with MSI-H metastatic colorectal cancer. T. André (Hôpital Saint-Antoine, Sorbonne Université, Paris. France).

11:15-11:35 Microbiome and immunotherapy of gastrointestinal cancer. F. Carbonnel (Kremlin Bicêtre Hospital, University Paris Saclay. France).


12:05-12:35 Coffee.


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6TH TABLE. METASTATIC COLORECTAL CANCER

Moderators: E. Aranda (Reina Sofía University Hospital, Córdoba. Spain). P. García Alfonso (University Hospital Gregorio Marañón, Madrid. Spain).

12:35-12:55 Therapeutic sequencing in metastatic colorectal cancer. E. Martinelli (Dipartimento di Internistica Clinica e Sperimentale ‘F Magrassi’, Napoli. Italy).

12:55-13:15 ctDNA in metastatic colorectal cancer: resolving resistance. F. di Nicolantonio (University of Torino, School of Medicine, Turin. Italy).

13:15-13:35 CTC in metastatic colorectal cancer: results of the VISNU Project. E. Díaz-Rubio (San Carlos Clinical University Hospital, Madrid. Spain).

13:35-13:55 Rare molecular alterations in metastatic colorectal cancer: new data. E. Élez (University Hospital Vall d’Hebrón, Barcelona. Spain).


14:25-14:30 Final conclusions and closing.

14:30-15:30 Lunch.

SCIENTIFIC PROGRAM


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GENERAL INFORMATION

VENUENH MÁLAGA HOTEL Calle San Jacinto, 229007 MálagaPhone: +34 952 07 13 23https://www.nh-hoteles.es/hotel/nh-malaga

ACCREDITATION

All registered attendees will be able to download the certificate of attendance and the accreditation of continuing training from the web of TTD Group.

The minimum attendance required to obtain the accreditation certificate is 80% of the total duration of the activity.

Symposium accredited with 1,2 credits by the General Secretariat for Research, Technological De-velopment and Health Innovation of the Regional Ministry of Health and Families of the Government of Andalusia.

LANGUAGESThe official languages of the Symposium will be English and Spanish, simultaneous translation will be available.

LUNCHDecember 12th Thursday, at 14:35 h NH Málaga HotelDecember 13th Friday, at 14:30 h NH Málaga Hotel


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GENERAL INFORMATION

CONFERENCE SECRETARIATSPANISH COOPERATIVE GROUP FOR DIGESTIVE TUMOUR THERAPYSusana Rodríguez FernándezC/ Téllez, 30 posterior. Piso 1º, Office 4.2 • 28007 Madrid. SpainPhone: +34 91 378 82 75 • Fax: +34 91 378 82 76 • Mobile Phone: +34 699 63 64 94E-mail: [email protected] • Website: www.ttdgroup.org

REGISTRATION FEES

General Registration fee: 810,00 EResidents fee*: 607,50 E*A document attesting fulfilment of resident physician condition must be provided.

Included in the registration fee are: attendance to scientific sessions, conference materials, certificate of attendance, refreshment breaks and lunch breaks.

ACCOMMODATION

DUI Double

NH Málaga Hotel****C/ San Jacinto, 2. 29007 MálagaPhone: +34 952 07 13 23https://www.nh-hoteles.es/hotel/nh-malaga

133 e 152 e

Barceló Málaga Hotel****Estación Vialia María Zambrano. C/ Héroe de Sostoa, 2. 29002 Málaga Phone: +34 952 04 74 94https://www.barcelo.com/es/barcelo-hotels/hoteles/espana/andalucia/malaga/barcelo-malaga/

167 e 179 e

Eurostars Málaga Hotel**** (previously Sercotel)C/ Héroe de Sostoa, 17. 29002 Málaga Phone: +34 951 01 01 50https://www.eurostarshotels.com/eurostars-malaga.html

132 e 143 e

Prices are per room and night. Breakfast and taxes included. Hotel room assigned on a first-come, first-served basis.

* Please, check with the Conference Secretariat for availability at the hotel before the payment.


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REGISTRATION FEE FORM OF PAYMENTRegistration fees can be paid by:

Checks payable to: Grupo de Tratamiento de los Tumores Digestivos.

Bank Transfer to: Grupo de Tratamiento de los Tumores Digestivos. Bankia. Sucursal Plaza de Castilla, 3. Account Nº: ES29.2038.1742.28.6000604214 BIC: CAHMESMMXXX Please, include the assistant name in the bank transfer.

A copy of payment must be sent to the conference secretariat together with the registration form. * Cancellations: Cancellations and refund request must be submitted in writing to the Conference Secretariat. There will be a refund of 50% of the total amount for cancellations received before 08 November 2019. After this date no refunds will be made. All refunds will be processed after the conference.

ACCOMMODATION FORM OF PAYMENTThe accommodation placement fee must be paid directly at the Grupo Viajabien Travel Agency:

Bank Transfer to: Grupo Viajabien. Calle Zurbano 45, Planta 6ª Account Nº: ES65 0081 0189 85 0001775684 BIC: BSABESBBXXX Please, include the assistant name in the bank transfer.A copy of payment must be sent to the conference secretariat together with the registration form.

RENFE offers attendees at the 27 International Symposium TTD discounts of up to 30% on train jour-neys. In order to obtain the reduction authorization form, please contact the Conference Secretariat.

OFFICIAL TRANSPORT AGENTS


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MAP

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Hotel NH Málaga****Calle San Jacinto, 229007 MálagaTel.: 952 07 13 23

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Hotel Barceló Málaga****Calle Héroe de Sostoa, 229002 MálagaTel.: 952 04 74 94

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Eurostars Málaga Hotel**** (previously Sercotel)Calle Héroe de Sostoa, 1729002 MálagaTel.: 951 01 01 50

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27 INTERNACIONALSIMPOSIO

PATROCINADORES OROGOLD SPONSORS

PATROCINADORES PLATINOSPONSORS PLATINUM

PATROCINADORES PLATASPONSORS SILVER

PATROCINADORES BRONCESPONSORS BRONZE

COLABORADORESOTHER CONTRIBUTORS


Documents

MÁLAGA 12th - 13th DECEMBER 2019...exclusively dedicated to the value of plasma in the CRC and new concepts in molecular biology in hepatocarcinoma and bile duct. The second day is