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LECTURE IV MICROBIOLOGY

Microbiology Lecture Vi

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FUNGI
 
$. !ungi lack chlorophyll
%.  & fungal cell "all contains cabohydrate called chitin  and plat cell "all have cellulose
'. ost fungi are not truly multicellular like plants
. !ungi are heterotrophic, "hile plants are autotropic
 
FUNGI
ainly for these reasons, fungi are placed in their o"n kingdom ! u n g i , "i thin the d o m a i n  Eukarya of the "tree of life“.
 MYCOLOGY   Study of fungi 
growth (vegetative) phase
FUNGI - MOLDS
gro" as long, tangled filaments of cells that give rise to visible colonies
 
are unicellular organisms "hosecolonies o n agar  visually resemble bacterial colonies.
 
!Y"!E
 -ith the notable eception of yeasts, fungi consist of masses of intert"ined filaments called h#$h%e (sing., hypha).
 
!Y"!E
 -ith the notable eception of  yeasts, fungi consist of masses of intert"ined filaments called h#$h%e (sing., hypha).
 
Thick mass of hyphae is called a &#celiu& (pi., mycelia).
 This mass is usually large enough to be seen "ith the unaided eye, and generally it has a rough, cottony teture.
 
FUNGI
eing eukaryotic organisms, fungi have one or more nuclei as "ell as a range of organelle including mitochondria , an endomembrane system, ribosomes, and a cytoskeleton.
The cell "all is composed of large amounts of chitin.
 
FUNGI
 
FUNGI
n many species of fungi, hyphal cross "alls, called septa (sing., septum), divide the cytoplasm into separate cells
 
FUNGI
n other fungal species, such as the common bread mold  Rhizopus, the filaments are nonseptate.
 
ecause fungi absorb preformed organic matter, they are described as heterotrophic organisms.
 
FUNGI
 
FUNGL GRO'T!
 
FUNGL GRO'T!
 
Oxygen The ma3ority of fungi are
 
%'4, a temperature close to normal room temperature.
6otable eceptions are the pathogenic fungi, " h i c h g r o" optimally at '74, " h i c h is b o d y temperature.
 
FUNGL GRO'T!
 p% a n y f u n g i t h r i v e u n d e r m i
l d l y acidic conditions at a p bet"een 5 a n d 8.
 
FUNGL GRO'T!
old contamination also is common in acidic foods such as sour cream, citrus fruits, yogurt, a n d most vegetables.
 
FUNGL GRO'T!
 
FUNGL GRO'T!
 
FUNGL GRO'T!
 
FUNGL RE"RODUCTION
S$o)ul%tion is the process of spore formation. t usually occurs i n structures called fruiting bodies,  "hich represent the part of a fungus in "hich spores are formed a n d from "hich they are released.
 
 SE1UL RE"RODUCTION
 &seual reproductive structures develop at the ends of speciali1ed hyphae. & s a result of mitotic divisions, thousands of spores are produced, all genetically identical.
a n y aseual spores develop "ithin sacs or vessels called s$o)%ngi%
 
 SE1UL RE"RODUCTION
*ther fungi p r o d u c e spores on supportive structures called conidiospore
These unprotected, dust+like
spores are k n o " n as conidia (sing., conidium/ conidio $ "dust"%. ( u n g a l spores are e)tremely light and are b l o " n about in huge numbers by " i n d currents.
 
n yet other fungi, spores may simply by fragmentation
of the hyphae yielding %)thos$o)e ( a r t h r o $ : 3 o
i n t ;)
 
a n y yeasts reproduce
aseually by budding. n
 
The parent cell can continue to produce additional blastospores.
 
 SE1UL RE"RODUCTION
* n c e free of fruiting body, spores landing in an appropriate environment have the capability of germinating to reproduce
ne" unicellular yeast cells or a ne" hypha
ontinued gro"th "ill eventually f o rm a mycelium.
 
n this process, opposite mating types come together and fuse
 
=ventually the nuclei fuse and a diploid cell is formed.
 
SE1UL RE"RODUCTION
t is advantageous because it provides an opportunity for the evolution of ne" genetic forms better adapted to the environment than the parent forms.
 
FIVE "!YL
 & fungus can be cataloged into one of five phyla, depending o n its mode of seual reproduction.
These phyla are the hytridiomycota, >lomeromycota, ?ygomycota, &scomycota, and the asidiomycota.
 
Ch#t)i+io&#cot%
The oldest kno"n fungi are related to certain members of the hytridiomycota, commonly called ch#t)i+s.
 
Secondly, being a2uatic, chytrids have flagellated reproductive cells.
6 o other fungi have motile flagellate cells, suggesting the other fungi lost this trait at some point in their evolutionary history.
 
Glo&e)o&#cot%
form "hat some consider the most etensive symbiosis on =arth.
 
Glo&e)o&#cot%
form "hat some consider the most etensive symbiosis on =arth.
 
FUNGL GRO'T!
 
The 2#go&#cot%
The p h y l um ?ygomycota consists of a group of fungi (.#go&#cetes) inhabiting terrestrial environments.
 
The 2#go&#cot%
embers of the phylum make up about one percent of the described species of fungi.
 
The sco&#cot%
embers of phylum &scomycota (asco $ "sac"% or sac fungi, commonly are called the %sco&#cetes.
The phyla contains many common and useful fungi, including  Saccharomyces cere&isiae #aker-s yeast%, *orchella
esculentum #the edile morel%, and Penicillium
 
The sco&#cot%
The p h y l um also has several members associated "ith illness and disease.
 spergillus flay us, produces aflato)in, a fungal contaminant of nuts and stored grain that is both toin and the most potent k kno"n natural carcinogen/
 
The sco&#cot%
 
ommonly kno"n as (%si+io&#cetes, are club fungi.
 
The sco&#cot%
 
FUNGL DISESES OF T!E S3IN
De)&%to$h#tosis (d e r m a t o $ " s k i n " + phyto $ :plant:, referring to the days "hen fungi "ere grouped "ith plants) is a general name for a fungal disease of the hair, skin, or nails. The diseases are commonly kno"n as tine% infections #tinea $ " w o r m " % ecause i n ancient times, "orms "ere thought to be the cause. Tinea infections include#
 athlete<s foot (tinea pedis)/
 head ring"orm (tinea capitis)/
 body ring"orm (tinea corporis)/
groin ring"orm or :3ock itch: (tinea cruris)/ a n d
nail ring"orm (tinea unguium).
De)&%to$h#tosis
The causes of dermatophytosis are a group of fungi called +e)&%to$h#tes. Epidermophyton currently is considered a mitosporic fungus, "hile species of Trichophyton #se)ual stage  rthroderma% and *icrosporum #se)ual stage 0annizzia% are ascomycetes
 
FUNGL DISESES OF T!E S3IN
Dermatophytosis is c o m m o n l y accompanied by blister+ like lesions appearing along the nail plate, in the "ebs of the toes or fingers, or on the scalp or skin.
 
C%n+i+i%sis
/andida alicans often is present in the skin, mouth, vagina, and intestinal tract of healthy humans, "here it lives "ithout causing disease.
The organism is a small mitosporic yeast that forms filaments called $seu+oh#$h%e "hen cultivated in laboratory media.
 
FUNGL DISESES
*ne form of candidiasisoccurs in the vagina and is often referred to as  4ul4o4%ginitis, or a :yeast infection.;
 
S$o)ot)ichosis
eople "ho "ork "ith "ood, "ood products, or the soil may contract sporotrichosis.
andling sphagnum (peat) moss used to pack tree seedlings or skin punctures "ith rose thorns (rose thorn disease) can lead to the disease as the result of infection by conidia from  Sporothri) schenkii
 
FUNGL DISESES
 
The most dangerous fungal diseases in humans.
t affects the lungs and is estimated to account for over %5 percent of all deaths from fungal disease.
aused by yeast kno"n as /ryptococcus neoformans
 
FUNGL DISESES
 
C)#$tococcosis
istoplasmosis is a lung disease most prevalent in the *hio and the ississippi 'i&er &alleys where it is often is called summer flu.
The causative agent is 1istoplasma capsulatum.
 
C)#$tococcosis
istoplasmosis is a lung disease most prevalent in the *hio and the ississippi 'i&er &alleys where it is often is called summer flu. The causative agent is 1istoplasma capsulatum.
C)#$tococcosis
 
FUNGL DISESES
 &cute blastomycosis is associated "ith dusty soil and bird droppings, particularly in moist soils near barns and sheds. nhalation leads to lung lesions "ith persistent cough and chest pains.
 
neumocystis pneumonia () currently is the most common cause of nonbacterial pneumonia in &mericans "ith suppressed immune systems.
 The causative organism, Pneumocystis iro&eci