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SHEACOSafety Health and Environment

Action Committee

Objectives of Consumer Safety News

To help maintain a high awareness of consumer safety issues amongst managers in our international business

To summarise recent safety problems in consumer products

To remind managers that the best operational strategy is a preventive approach, known as Quality Assurance

To remind managers of the technical expertise which is available within Unilever

To encourage sister Companies to share information

Compiled for the business by the Consumer Safety Sub-committee of SHEACO

Editor: Mrs T M Herd, SEAC Colworth

Assistant Editor: Mrs M Wood, SEAC Colworth

FILLIN "Please start typing here" \* MERGEFORMAT Page

4. Editorial

5. BSE Update

6. Workshop on (microbiological) Risk Assessment within UnileverSEAC Conference

7. Tolerance of Listeria monocytogenes in ready to-eat-foods: summary of an FAO/WHO expert consultation8. Biotech Digest

9. Mass Spectrometry in Food Safety Meeting at Colworth

10. World Class Quality rolls out through supply chain

11. Responsible Use of Antibiotics in Food Animal Production

12. Unilever Consumer Safety Incident Birds Eye potato waffles recalled

14. Hot TopicsInvestigation of Salmonella outbreak reveals potential for problems

15. BSE Control steps taken by EU, Australia and New Zealand Levels of dioxins/PCBs in farmed salmon cause UK media concern

16. Elevated levels of the pesticide chlormequat found in fresh and processed Italian tomatoes

17. Who can help you

Editorial

Happy New Year to all readers of Consumer Safety News.

A newsletter will only be read if it delivers current news items in a timely manner. Over the past year we have struggled to keep up with the amount of external (to Unilever) information that is published by the media. In the past, such information would have formed the basis of our overview of incidents and summary of news from far and wide. However, so many people can now access such information directly via the Internet we no longer feel that we can add value by repeating these stories a couple of months after they were real news. We have therefore decided to give our news section a fresh look. This new hot topics section will only feature items that are of high concern to Unilever and where we can add information to the published text. Readers wishing to keep up to date with the news as it happens should make use of the many food news feeds now available. Some good examples are:

FSnet this is a free daily email service that is completely safety focused. To subscribe to FSnet, send mail to:[email protected], leave subject line blank in the body of the message, type: subscribe fsnet-L firstname lastname. Other useful web sites include:

http://www.just-food.comhttp://www.foodnavigator.com

In many cases (as with FSnet) you can request an alert to be sent directly to your own email account. We are also exploring ways of making these sources directly accessible from SEAC Online.

CSN will continue to feature original articles and be a forum for sharing news and best practice in consumer safety within Unilever. This issue contains a timely update on BSE as the rest of Europe finally wakes up to the fact that BSE is not just a UK problem. Cases are continuing to appear in European countries, followed by the predictable knee-jerk reaction from consumers and regulators alike. In response, Unilever has recently revised its guidance on BSE. As before, the aim of such guidance is to ensure an agreed approach within Unilever and a reminder that Unilever actions should do nothing to increase consumer anxieties about BSE because of the uncertainties or lack of knowledge.

Last year Unilever had a total of 6 public recalls. In each case there will be lessons to be learned and shared but how often have you been made aware of them? Companies are rarely willing to do this on a global level and so we are very gratified to be able to publish the lessons learned following an incident of metal contamination in a frozen food. My thanks to the Foods QA Group and Tony Heaney for this valuable contribution.

Dont forget you can access the news weekly on SEAC Online see http://seac.research.unilever.com

Teresa Herd

Editor:

Additions/amendments to circulation list:

Mrs T Herd

SEAC Enquiry Service

SEAC

Unilever Research Colworth

Unilever Research Colworth

Colworth House

Colworth House

Sharnbrook

Sharnbrook

Bedford MK44 1LQ

Bedford MK44 1LQ

UK

UK

Tel: (44) 1234 222686

Tel: (44) 1234 222700

Fax: (44) 1234 248054

Fax: (44) 1234 248054

Outlook: Herd, Teresa

Outlook: SEAC, Enquiry-Service

Email: [email protected]

Email:[email protected] update

As numbers of cases of BSE in cattle have continued to increase in Europe, there has been a resurgence of interest in vCJD/BSE both in the media and in the scientific literature. This has prompted regulators to impose new restrictions on the industry (see Hot Topics). A summary has been prepared for SHEACO to outline this new information and to re-assess the risks to Unilevers operations. The main points are captured below.

Summary

Since 1996, the awareness of BSE has increased tremendously and effective measures have been put into place in the beef-chain to minimise the impact of BSE on public health.

As at December 2000, there have been 87 cases of vCJD in the UK. This includes a cluster of 5 cases. Statistical analysis shows that this number of cases in this one area is unlikely to have occurred by chance. Investigations are focussing on the genetic susceptibility of the victims and the possibility of a common food source such as meat. vCJD is still a rare disease, despite the rising incidence in the UK. Whilst the causative agent is the same as that which causes BSE in cattle, the route of infection for man is still unknown.

The BSE epidemic in UK cattle continues to decline. The EU Scientific Steering Committee has completed a 23 nation geographic assessment of the likely risks of BSE in the cattle populations. Overall, the BSE risk has decreased or stabilised since 1996. The levels of the BSE agent in the beef-chain in EU countries should decrease still further once the EU decisions on rendering and specified risk materials (SRMs) are appropriately implemented.

Milk is still regarded as safe, but investigations to remove any doubt are underway in the EU, especially in the UK.

The source of the BSE epidemic is still unknown. The prion, which causes BSE in cattle, is different from the prions known to cause scrapie in sheep. We do not know if BSE occurs naturally in sheep, nor whether it could have been transferred from cattle to sheep as a consequence of the BSE epidemic. If BSE is found in sheep, there will be an immediate 'scare' with damage to the sheep/lamb industry.

In the light of all the new information, the 'real' safety risks to consumers through Unilevers operations are likely to remain low both for Foods and for HPC. However, the 'perceived' risks are still high and are likely to remain so in the foreseeable future. 'Scares' are likely to arise anytime from anywhere. Unilever still needs to be concerned about the BSE/vCJD issue. The Business Groups should now take the lead to ascertain how Unilever should manage the 'perceived' risks involved.

Unilever BSE guidance

The document Unilever guidelines on BSE is available in the SHEACO database in Lotus Notes CORP\A1388655.nsf or via the intranet at http://upn.unilever.com . This replaces the former BSE policy and implementation guidelines. The SHEACO fact sheet is also being updated and will be available soon.

Teresa Herd - SEAC Information

Workshop on (microbiological) risk assessment within Unilever

On 27th of November a workshop on Risk Assessment within Unilever was organised by the Microbiological Risk Assessment team based at Colworth House and Vlaardingen. The workshop was attended by 26 people from the business (incl. Bestfoods and Slimfast) and research representing twelve countries worldwide.

Aims of this workshop were to introduce participants into risk assessment within the Unilever business as a standardised approach to judge the acceptability of risks and above all to discuss its benefits for Unilevers food and HPC companies. At first the views on risk analysis from a SEAC perspective were shared with the participants, whereafter risk assessment in SEAC-Toxicology was discussed. The third presentation covered views on microbiological risk assessment (MRA) in SEAC-Microbiology and the project MIRACLE. Objectives of this project are to create awareness in the business, to develop MRA expertise and implementation of its knowledge in relevant expert systems and to influence external MRA developments relevant to the SEAC Risk Analysis initiative. During the last item of the workshop various speakers clarified statements of risk assessment resulting in valuable discussions involving both the business and research. Detailed information of this workshop can be obtained from the authors of this article.

Frank Pieterman and Suzanne van Gerwen - SEAC Microbiology Vlaardingen (on behalf of the MIRACLE project team)

SEAC Conference, 6-10 November

The Unilever Business was invited to attend a week of SEAC meetings in November, to learn about and to discuss the latest developments within SEAC.

The SEAC Overview on Monday included our vision for the future, and detailed the various business support processes and activities, e.g. the SEAC Enquiry Service, SEAC Support Service and "Pelican" - a web-based system that will provide a single integrated SEAC process for formal Unilever safety clearance.

The SHEACO Contaminants Working Party (CWP) was held on Tuesday and Wednesday.

Topics discussed included the impact of global buying, regulatory issues, GMOs, corporate relations, management of incidents, knowledge management, the new SEAC Allergens website and some exciting HPC product innovation concepts. An extensive poster session and practical demonstrations gave the opportunity for in depth discussion of specific topics. There were tours of the Unipath production facility at Bedford, and of the Colworth Consumer Science (with a challenging taste panel in the sensory booths - attempting to spot the difference between ordinary and low fat-potato crisps) and the Ice Cream Pilot Plant (tasting Magnums and Soleros!).The SEAC Contaminants Business Review and the SEAC Microbiology Business Review were held on the Thursday and Friday, with detailed description and discussion of their respective programmes. Please contact Peter Brawn and Peter McClure for details.Approximately 60 representatives from the Unilever and BestFoods Business attended the meetings and gave very positive feedback. Planning for next year's meetings has already started!John Wilkins SEAC ContaminantsTolerance of Listeria monocytogenes in ready to-eat-foods: summary of an FAO/WHO expert consultationAs mentioned previously in CSN, project MIRACLE develops Microbiological Risk Assessment (MRA) for Unilever. MRA determines risks throughout the food chain using qualitative and quantitative data. One of the objectives of the MIRACLE project is to create awareness of MRA to the Unilever business and to keep the business informed on ongoing developments. Below the current state of affairs with respect to tolerance of Listeria monocytogenes in ready-to-eat foods from a regulatory perspective is given. Note: the observations are provisional and no legal consequences can be drawn at this point.

The FAO/WHO has prepared a preliminary report on exposure assessment of L.monocytogenes in ready-to-eat foods for the Joint FAO/WHO Expert Consultation on Risk Assessment of Microbiological Hazards in Foods (Report MRA 00/02). This report refers to a discussion paper on the management of Listera monocytogenes in foods (Annex of the Codex report CX/FH 99/10), which concluded on the basis of a risk assessment that a concentration of L. monocytogenes ( 100/g at consumption is of low risk to the consumer. However, some concerns remained within Codex on the meaning of low risk.

The additional approach in report MRA 00/02 should:

i) give a better quantification of low risks using predicted levels of exposure to

L. monocytogenes and observed incidence of listeriosis.

ii) provide a specified level of contamination, which represents an acceptable risk.

iii) evaluate health consequences of a policy that regulates absence of L. monocytogenes in 25 grams (zero tolerance) compared to a model which accepts a certain amount of L. monocytogenes in the products (e.g. 100 CFU/gram).

Several approaches were used to address the risk question. One approach identified the estimated prevalence of listeriosis in different nations. Of those nations for which data were available, Italy, USA, and Australia have 'zero tolerance' policies, and some other countries tolerate low levels of L. monocytogenes. It was concluded that 'The data on prevalence of listeriosis do not provide strong support that a zero tolerance policy provides a greater level of public health protection than other, less stringent, regulatory approaches.

Based on an analysis (US data) it was assumed that each consumer was exposed many times per year to L. monocytogenes with the majority of doses between 0.01 to 10 CFU per serving (note: 0.01 CFU/serving can be interpreted as 1 L. monocytogenes in 100 servings). Other approaches studied levels of exposure to L. monocytogenes and related this to the reported number of outbreaks. A small percentage (0.21%) of the doses were predicted as more than 106/serving. The predicted incidence of exposure to products heavily contaminated with

L. monocytogenes greatly exceeds the reported incidence of listeriosis.

As a conclusion it was stated 'In the context of the results and analyses presented, it appears that whether the regulatory policy is e.g. 100 CFU/g at the point of eating or 'zero tolerance' is irrelevant unless the policy can be strictly enforced.'

In the EU a Draft Commission proposal on regulatory controls is in preparation, also a draft risk assessment has been produced by the FDA/FSIS and is available for comment at http://vm.cfsan.fda.gov/~dms/lmrisk.html.

Suzanne van Gerwen and Frank Pieterman - SEAC Microbiology Vlaardingen (on behalf of the MIRACLE project team)

Biotech Digest

The Biotech Digest is a newsletter produced by Dr. Min-Min Teh, part of the Foods Regulatory Affairs team at Colworth. This newsletter is intended as an update on scientific issues in Genetically Modified (GM) food and related topics. The first issue was published in November 2000 and focused on GM issues in animal feed. Articles included are:

Attitudes to GM-fed animal produce in the UK

Reaction of the food industry (to demands for GM free animal feed)

Is there enough non-GM animal feed?

What's wrong with GM proteins?

'Jumping genes'

EU Novel Feed legislation

Unapproved maize discovered in taco shells

Skylark-ing around (will GM herbicide-tolerant sugar beet reduce the Skylark population?)

Do GM crops harm butterflies?

The Biotech Digest will be published every two months and is accessed through the FRESCO website (http://fresco.unilever.com) in the section "What's new".

Min-Min Teh Regulatory Affairs, ColworthMass Spectrometry in Food Safety Meeting at Colworth

Over 70 delegates (40 from outside Unilever) attended this combined British Mass Spectrometry Society, RSC Analytical Biosciences Group and Society of Chemical Industry meeting at Colworth on 20th November.

Following a welcome from Prof. Peter Lillford, Colworths Chief Scientist, Prof. Stephen Barnes of the University of Alabama (Birmingham, USA), opened the scientific session with an erudite presentation on the advantages of Liquid Chromatography/Mass Spectrometry (LC/MS) for the measurement of isoflavones and other polyphenols in foods and physiological fluids. His talk was timely, given the current debate about the advantages and disadvantages of dietary phytoestrogens, and contained some interesting metabolic data.

Dr Andy Boseley of Syngenta (ex Zeneca, Jealotts Hill) described the rapid analysis of agrochemicals in crops by LC/MS. He demonstrated the reduced sample preparation and faster analysis time available by using up to date mass spectrometric methods. Impressive data were presented on the determination of pesticides and their metabolites using very rapid (often sub-minute) analytical regimes.

David Wood of SAL Ltd (Manchester) gave a topical (given recent contamination problems in Belgium) and absorbing presentation on mass spectrometric determination of dioxins and PCBs in foods. Davids talk impressed the audience with the challenging nature of the analyses and the ability of modern high-resolution Gas Chromatography/Mass Spectrometry to meet and surpass the required detection limits.

After a break for lunch, poster sessions and a manufacturers exhibition, Dr Thrse McKenna of Micromass UK Ltd. (Manchester) introduced a new application of MALDI-ToF (matrix-assisted laser desorption ionisation time-of-flight) mass spectrometry as a rapid method for speciating and typing micro-organisms. Sophisticated pattern matching software not only enabled species discrimination, but also allowed identification of different strains within species. The methodology was still undergoing development but preliminary data indicate that it is rapid, robust and reproducible. The technology has obvious potential in the study of food pathogens.

The final talk was given by Dr John Lewis of CSL, York and emphasised the importance of establishing the chemical form of a mineral toxicant. John gave a useful insight into the power of hyphenated LC/ICPMS methods for studying cadmium and arsenic species, and also into Inductively Coupled Plasma -MS analysis of the products of in vitro systems that simulate the gastrointestinal system.

We hope to host another food-related MS meeting at Colworth in 2002.

John Wilkins SEAC Contaminants

World Class Quality rolls out through supply chain

Raising standards of quality will improve business performance, says Markham

A standard has been set for quality and excellence throughout the whole supply chain and is now being rolled out throughout Unilever following a conference in the Netherlands in November 2000.

Called the Unilever Quality and Consumer Safety Road Map, this comprehensive manual of quality assurance is available on the intranet at http://uqcsrm.unilever.com. The 'road map' identifies three levels of development for quality management systems: core or minimum standards that all business should have in place; extended elements that depend on local needs; and leading edge elements, procedures that lead to competitive advantage.

The conference on 'World class quality' was attended by around 60 key personnel in quality assurance from across the business including HPC, DiverseyLever, Research and Foods, including Bestfoods. At last year's conference the 'road map' was mapped out, while this year, delegates looked at implementation of the new system and sharing and reviewing best practice.

On Tuesday, delegates visited the Heineken factory in the Netherlands, to see how the company tackled quality management. The evening before, at the official dinner, they heard Claude Francotte of GB, a major Belgian retailer, explain what he expected of a relationship between a company like his and Unilever.

Opening the forum on Monday, Rudy Markham, strategy and technology director, said: "During the conference, you will work at agreeing what world class quality really means and how best to implement the road map principles. Your challenge is to deliver world class quality management in your business unit, but doing this by sharing your best practices and implementing them from others."

"Our people, products and processes must be the best in the market. Moving to fewer brands, produced in fewer factories, the risk of our exposure to shortcomings in quality increases dramatically. Together with more demanding customers and consumers we must work with smaller quality tolerances, both in manufacturing processes as in our control and acceptance procedures."

Mr Markham pointed out that incidents of poor quality continue to occur in many parts of the business from product design, through to sourcing, manufacturing and delivery and he cautioned that the statistics of quality incidents may only be the tip of the iceberg.

"We have to tackle the root causes," he said. "Like we learn in TPM, ask at least three times 'Why?' to get to the bottom of a problem."

The Foods Quality Assurance group has just established its presence on the Unilever intranet. At the moment the site contains all of the presentation materials used at the Unilever Quality Conference held in November in Noordwijkerhout. You can download the files for your own information, or to share the messages and learnings with your teams. In the near future, we will be adding much more content, covering our activities, training courses and aspects of Quality Management in Foods Division.

The URL is http://fqag.unilever.comPaul Whitehouse FQAG, Rotterdam

Responsible Use of Antibiotics in Food Animal Production

Objective

The objective of this Guideline is to support Unilever companies in dealing with possible product safety/quality hazards and loss of reputation arising from uncontrolled use of antibiotics in the supply chain. At the same time this guideline should permit Unilever to respond to market and consumer wishes. The Guideline provides:

A co-ordinated and defensible Unilever approach with respect to antibiotic use to ensure:

i.consumer safety and brand protection

ii.environmental care

iii.animal health

Guidance about sourcing materials of animal origin, for which antibiotic use may be an issue.

Practical Guidance

Unilever buying organisations should specify that:-

Only legally approved antibiotics are being used on the farms of their suppliers:

All antibiotics should be used under veterinary advice and in accordance with the recommendations in the data sheets that are supplied by the manufacturers:

QA schemes on the farm should document all antibiotic usage; withdrawal periods must be complied with and documented as required by legislation.

Preference should be given to suppliers, whose farmers:-

Control disease by Good Farming Practices, (e.g. farm hygiene, selection of breeding stock, feed free of salmonellas) rather than by antibiotics:

Do not use antibiotics, including growth promoters, in place of optimal nutrition, good management and site hygiene

Suppliers should due diligence monitor and record the levels of antibiotic residues in animal products, in addition to any analyses that may be required by law. Additional tests by the receiving company should be at their discretion.

The full fact sheet is available in the SHEACO database in the Fact Sheets and News section or as a down load on the SEAC website (http://seac.research.unilever.com) in the News archive area.

FDA Task Force on Antimicrobial Resistance:

http://www.fda.gov/oc/antimicrobial/taskforce2000.html

John Crowther & Sara Stewart SEAC Microbiology, Colworth; John Wilkins & James Harris SEAC Contaminants, Colworth;

Martin Michels FBE, Rotterdam

UNILEVER CONSUMER SAFETY INCIDENT SUMMARY CS2

Product: Birds Eye potato waffles

Date: Nov-Dec 2000Manufacturing Company: Birds Eye Walls Ltd

Manufacturing Country: UKMarketing Countries: UK and Ireland

Nature of Incident: Metal contamination

People Affected: One claim of minor mouth injury

CAUSE: The contamination occurred when equipment on the production line was damaged. A bearing at the exit end of a potato blancher suffered partial failure without impairing its function. As a consequence the shaft dropped slightly and a part of a de-watering screen, at the exit to the potato dice blancher, became damaged. This was due to undetected contact between a moving part of the equipment and a stationary part. This led to progressive wear and ultimately to degradation of part of the screen, and consequently to some metal pieces entering the product stream. The combination of stainless steel and the dimensions of the contaminants prevented detection by metal detectors that were set at 2mm. The problem had been discovered in the factory and production had been restricted according to best judgement. ACTION TAKEN BY COMPANY: A customer-call to the Careline alerted the company, so the problem obviously existed prior to the restricted period. The company issued a public recall. The recall could have been initiated earlier if the Careline had been aware of the original problem in the factory. Product involved was either held by BEW, destroyed by stores, or returned to BEW. An independent audit of factory controls and procedures was undertaken. A number of recommendations relating to the root cause and factory controls have been made and will be implemented. The company is exploring options for the improvement of metal-detection capabilities. The company also identified an additional Critical Control Point in the line.

OUTSIDE BODIES INVOLVED:

Retailers were contacted regarding details of recall.

The Home Enforcement Authority (HEA) were advised of recall by BEW and fully briefed. Good contact was maintained with the HEA.

A local enforcement office handled one of the complaints. No action was taken by them.

Various media carrying the recall notices.

BEW are respected by retailers and enforcement authorities as a business ready and willing to act quickly and efficiently for consumer safety. They therefore suffered very little adverse publicity.

LESSONS TO BE LEARNED: HACCP studies for production equipment need to focus on the possibility that certain components designed to function with clearance between them may come into contact causing progressive wear and product contamination.

Equipment of this nature which operates within enclosures needs to be regularly inspected.

Metal detection cannot be regarded as a control method for metal contamination, only as a last protection for large contaminants.

Good two-way communication between Consumer Care and the factories are important to minimise the impact of product contamination on both consumers and product.

The ability to manage a successful recall and maintain support from interested parties is helped by having a good reputation as a business of high standards and competence in matters of consumer safety, together with an open and honest approach.

Tony Heaney BEW; Maggie Wood SEAC Information

Hot Topics

Investigation of Salmonella outbreak reveals potential for problems

An outbreak of S. Typhimurium PT 12 food poisoning in South Australia during 1998 was linked to the consumption of a brand of chicken nuggets. Ten cases of illness were recorded among consumers aged between 3 and 14 years. S. Typhimurium PT 12 was isolated from an opened sample of the implicated brand of nuggets retrieved from one of their homes.

The implicated nuggets were a coated product containing raw poultry that had been flash fried during production in order to set the batter. Some similar brands are fully cooked through to the centre during manufacture. The implicated nuggets were voluntarily recalled by the producer.

Fully cooked and flash fried chicken nuggets provide the consumer with different levels of microbiological safety. Products that are fully cooked by the manufacturer are likely to be free of infectious pathogens and will be safe, even if the consumer only warms them. Flash fried products containing raw or undercooked poultry, will not be free of infectious pathogens after manufacture and thus require cooking (70oC for 2 minutes) by the consumer to make them safe for consumption.

With similar brand positioning, similar packaging and the name chicken nuggets, there is a real potential for consumers to confuse these products and assume that they are all fully cooked. This is a problem because the external appearance of the products is similar and, if they are cut open, the flash fried products do not always have the translucent appearance of obviously undercooked chicken. Safe product use is therefore not obvious to the consumer. Requirements for safe use are further confused because the cooking instructions for the products are similar e.g. 15-20 minutes at 200oC for fully cooked nuggets and 20-25 minutes at 200oC for flash fried nuggets.

This food poisoning outbreak originated because consumers perceived and handled a raw product as if it was fully cooked. Although valid cooking instructions were placed on the packaging, the product appearance and name obscured the difference in risk. The lesson to learn for Unilever is that without clear differentiation between ready-to-eat and raw products, adequate labelling with cooking instructions is not sufficient to ensure safe handling and preparation. Where there is a high risk of the raw materials containing pathogens (e.g. poultry), the best way to prevent such outbreaks affecting Unilever is to continue to market products that have been fully cooked during processing.

Reference: WHO Surveillance Programme for Control of Foodborne Infections and Intoxications in Europe Newsletter, No. 64, June 2000.

Martyn Brown, Peter McClure and Niteen Sawant SEAC Microbiology, Colworth.

BSE

The first ever cases of BSE in native born cattle have been reported from Italy, Germany and Spain and cases continue to be reported from other countries. This news, in addition to the question marks over the implementation of Community safety laws on BSE in the Member States and the collapse in consumer confidence in the safety of beef has prompted the European Commission to impose a series of additional measures. They include:

a temporary ban on the feeding of meat and bone meal (MBM) to all farm animals

a requirement that all animals over 30 months are tested for BSE to enhance consumer confidence

a requirement that the current list of specified risk materials (SRMs), which must be removed and destroyed, should now also include the entire intestine of bovines of all ages

a "purchase for destruction" scheme to remove from the food chain all cattle aged over 30 months unless they have been tested for BSE to ensure additional guarantees and to rebalance the beef market

The European Commission also formally adopted a proposal to require the testing of all "at risk" animals from 1 January 2001. This requirement will be extended to all animals aged over 30 months from 1 July 2001.

Australia and New Zealand have announced that they are to ban imports of beef from 30 European nations following concern about BSE and vCJD.

Teresa Herd SEAC Information, Colworth Levels of dioxins/PCBs in farmed salmon cause UK media concern

Recently a number of researchers have identified significant concentrations of dioxins and PCBs in fish, including wild and farmed species. A researcher from Surrey University has called for further investigation of the impact of dioxins and PCBs in feed on the concentrations found in the flesh of Scottish farmed Atlantic salmon. The recent media interest in farmed salmon coincided with a programme on the subject scheduled to be televised by the BBC on Sunday 7th January. The UK Food Standards Agency (FSA) expressed concern about BBC News manipulation of public concern to boost viewing figures. The FSA has advised that the long-term health benefits from modest consumption of fatty fish in a balanced diet outweigh concerns over chemical contaminants.

SEAC has anticipated this issue with a continuing programme of surveillance of fish for chemical contaminants, including dioxins and PCBs. A statement has also been prepared containing some background information on this issue plus giving the position re WHO and EU limits. It was produced jointly by Chris Wright (SEAC Contaminants) and Andy Crimes (Regulatory Affairs Foods). It can be obtained from either of them or the SEAC Enquiry Service.

Chris Wright SEAC Contaminants; Andy Crimes Regulatory Affairs Foods

Elevated levels of the pesticide chlormequat found in fresh and processed Italian tomatoes

In December 2000 an EU Food Alert was issued concerning levels of chlormequat in certain fresh and processed tomato products exported from Italy to Belgium. The Belgian authorities sampled nine batches on 5 September and found residues of chlormequat in six batches at 0.19, 0.89, 0.18, 0.49, 0.08 and 0.08 mg/kg. All of these residues were in excess of the EC MRL (Maximum Residue Limit) of 0.05 mg/kg, which is set at the limit of determination and will apply from 1 July 2001. Four manufacturers were named:

Cirio Napoli Italia.

Elvea SRL, Via Nazionale 239-241, 84015 Nocera-Superiore (SA) Italia.

Giaguaro S.P.A., Via Ingegno Sarno Italia.

Napolitano CEG & Co 84205 Eboli.

The importers/retailers were Colruyt; C.B.C. Kronenburg-Straat 55, 2000 Antwerpen; and Nino Ferrardi, Brussels.

Chlormequat chloride is a plant growth regulator used for stem shortening in cereals, to improve fruit setting in pears, almonds, vines, tomatoes and to prevent premature fruit drop in pears, apricots, plums etc. It is also used on cotton, vegetables, tobacco, and sugar cane and to produce more compact plants in horticulture.

A previous issue in the UK with levels of chlormequat found in pears during 1999 suggests that it leaves quite persistent residues. The problem is compounded by the fact that EU MRLs for chlormequat will all be set at the limit of determination from 1 July 2001 with the exception of certain cereals.

The tomato manufacturers named in this incident are all located in the South of Italy near Sorrento and none are Unilever suppliers. It is not clear yet whether the residues are caused by actual application on the tomato crop or some form of cross contamination. It has also been suggested that it could be coming from Chinese tomato paste imported into Italy, but this seems unlikely as it was also found on fresh tomatoes.

A risk assessment carried out by the Pesticide Safety Directorate suggests there is no unacceptable risk to health involved from these levels (SEAC Toxicology are also carrying out a risk assessment). However SEAC Contaminants recommends that the business obtain assurances from suppliers for any vulnerable materials that residues of chlormequat are below the EU MRL, preferably backed up by analytical results. If this is not available it may be prudent for companies to have their own analyses carried out but it should be noted that this compound is difficult to determine analytically, and will not be covered in a normal pesticide screen. As SEAC Contaminants are not set up to perform the determination at present it is suggested companies use the UK Central Science Laboratory contacting Mr S Brewer, Tel: 01904 462448, Fax: 01904 462111 for details. Expect to pay about 150 per sample. Please inform SEAC Contaminants of any results obtained.

Chris Ebden SEAC Contaminants

WHO CAN HELP YOU?

Amendments are shown in bold italic

QUERYFOODSPERSONAL CAREHOME CAREDIVERSEYLEVER

GENERAL SHE

ENQUIRIESFor any safety-related questions please contact the SEAC Enquiry Service

Outlook: SEAC, Enquiry-Service; email: [email protected]: http://seac.research.unilever.com; (Tel: 44 1234 222700; Fax: 44 1234 248054)

HYGIENIC PROCESSING &

PLANT DESIGNSEAC (Fax: 31 10 4605188)

Roy Curiel (Tel: 31 10 4605766)URPS (Fax: 44 151 6411824)

Mrs D L Woodall (Tel: 44 151 6413977)

URPS (Fax: 44 151 6411803)

Dr C A Eastwood (Tel: 44 151 6413279)

URPS (Fax: 44 151 6411803)

Dr C A Eastwood (Tel: 44 151 6413279)

TOXICOLOGICAL ADVICE & CLEARANCESEAC(Fax: 44 1234 222122)

Dr P Hepburn(Tel: 44 1234 222125)

SEAC (Fax: 44 1234 222122)

Dr G R Gilpin (Tel: 44 1234 222432)

Outlook: SEAC, Toxicology-URC; email: [email protected]

MICROBIOLOGICAL ADVICESEAC(Fax: 44 1234 222277)

Mr D Kilsby (Tel: 44 1234 222986)

Dr P McClure (Tel: 44 1234 222010)URPS (Fax: 44 151 6411800)

Mr P Jay (Tel: 44 151 6411672)

SEAC(Fax: 31 10 4605188)

Dr L Gorris (Tel: 31 10 4605709)Miss D Murphy (Tel: 44 151 6413185)

CHEMICAL CONTAMINATIONSEAC (Fax: 44 1234 222599)

Mr P R Brawn (Tel: 44 1234 222011)

URVl(Fax: 31 10 4605671)

Dr M Lipp(Tel: 31 10 4605214)

Crisis Telephone (Tel: 44 1234 781781)SEAC (Fax: 44 1234 222599)

Dr S Lalljie (Tel: 44 1234 222597)

Crisis Telephone (Tel: 44 1234 781781)

METHODS OF ANALYSISURVl - UMA Foods (Fax: 31 10 4605671)

Mrs Dr Y S J Veldhuizen (Tel: 31 10 4605463)URPS - UMA B and UMA E (Fax: 44 151 6411801)

Mr A Loosley (Tel: 44 151 6411669) email: [email protected], Maarssen

Mr R Dohmen (Tel: 31 30 2476812)

QA CONTACTSFQAG Rotterdam (Fax: 31 10 2174149)

Central Asia/ China, EAP: Mr J van der Jagt (Tel: 31 10 2174865) AMET, LA: Mr B Debets (Tel: 31 10 2174293)

SERIOUS PROBLEMS OR INCIDENTSProduct Incident Manager (24h Tel: 31 10 2174466)

FQAG Rotterdam (Fax: 31 10 2174149)

For follow up reports only, you can use Outlook: FQAG, Incident Manager or email: [email protected]

Head of SEAC: Dr B Sangster (Tel: 44 207 8225291) (Fax: 44 207 8225881)

For medical advice relating to Occupational Health, contact your local Occupational Health Service or:

Head Corporate Occupational Health: Dr John Cooper, UH London (Tel: 44 207 8225871 or out of office hours: 44 207 8225252)

Head Occupational Health Europe: Dr Bernard Luten, UNV Rotterdam (Tel: 31 10 2174989 or out of office hours: 31 10 2174000)

Consumer Safety News and all SHEACO documents are available on the SHEACO Lotus Notes database. Additions/amendments to the circulation list of Consumer Safety News should be sent by email to the SEAC Enquiry Service. Requests for SHEACO documents should be sent by email to Sandra Darton at the SHEACO Secretariat, Unilever House, London.

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Consumer Safety

Consumer Safety

News

News

SHE

SHE

ACO

ACO

Safety Health and Environment

Action Committee

A SUMMARY OF NEWS AND VIEWS FROM

AROUND THE WORLD

February 2001 2000

Issue Number 56

Unilever

For Unilever internal use only