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Michael Schroeder BioTechnological CenterTU Dresden Biotec
Bioinformatics I
By Michael Schroeder, Biotec 2
Bioinformatics
BIOlogy
matheMATICS
INFORmatics
By Michael Schroeder, Biotec 3
Bioinformatics
Bioinformatics = Biological + Informatics - Logical
By Michael Schroeder, Biotec 4
How to teach bioinformatics
Applied bioinformatics Use bioinformatics tools to answer biological questions
Programming for bioinformatics Learn how to use databases and how to programme in
Python
Term 3: Structural and computational biology
By Michael Schroeder, Biotec 5
Structure of module Overview
A bit of everything A web tour:
online resources for DNA and protein sequences, protein structures and expression data
Sequence comparison Dot plots Dynamic programming Substitution matrices Multiple alignments BLAST PSI-BLAST
Phylogeny Protein structure
By Michael Schroeder, Biotec 6
Practicals Two types:
Bio: You’ll be given a biological questions and you’ll use online resource to answer the question
Computing: You learn about Unix and Python, however you need to teach yourself, too. Please buy a Python book
Each week you work through some questions during the lab and do some homework
Joachim Haupt and Janine Roy
By Michael Schroeder, Biotec 7
Assessment Written exam counting 80% of final mark Practicals: Test during lab (week 10) and homework counting
20% Test: Will involve using online tools and resources to answer
some questions Homework: you must pass at least 10 homework assignments
(there will be 13 overall). Passing means that >50% of your answers are correct
For homework you get pass/fail For the test you get a mark given that your homework is pass
Strategy for preparation Buy book Read book Follow slides Do all labs and homework
By Michael Schroeder, Biotec 8
Getting in touch
Email: [email protected]
Web site: http://www.biotec.tu-dresden.de/schroeder
Includes web site for bioinformatics modules
By Michael Schroeder, Biotec 9
Modules text book
Chapter 1 is online at the module web site
