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ORAL PRESENTATION Open Access Methods for evaluating changes in cartilage stiffness following electromechanical reshaping Amanda Lim * , Dmitriy Protsenko, Brian Wong From 2nd Scientific Meeting of the Head and Neck Optical Diagnostics Society San Francisco, CA, USA. 23-24 January 2010 One component of several otolaryngological surgeries is the reshaping of cartilage. Several previous studies have demonstrated the efficient achievement of this procedure through electromechanical reshaping (EMR), a technique that involves the direct application of voltage to cartilage mechanically deformed in a jig. Two main parameters, voltage and application time, may be varied to achieve varying degrees of shape change. Both maximized shape change and minimized intrinsic tissue damage determine the ideal parameters for EMR. In preceding research, EMR parameters were correlated with degree of shape change. However, it remains necessary to correlate the same parameters with the degree of change in the mechanical properties of tissue. This study satisfies this need by providing comprehensive data on the pre- and post-EMR stiffness of both septal and auricular cartilage over a range of voltages with constant applica- tion time (2-8V, 2min, and 2-8V, 3min, respectively). EMR was applied using flat platinum electrodes to one of two 15mm X 5mm samples obtained from the same car- tilage specimen, while the second sample was maintained as a control. Following a 15 min rehydration period, the Youngs modulus of the tissue was calculated for both the control and experimental sample from data obtained through a uniaxial tension test. A general reduction in stiffness was observed from beginning at 3V, with the magnitude of reduction increasing at 6V. Published: 29 October 2010 doi:10.1186/1758-3284-2-S1-O18 Cite this article as: Lim et al.: Methods for evaluating changes in cartilage stiffness following electromechanical reshaping. Head & Neck Oncology 2010 2(Suppl 1):O18. Submit your next manuscript to BioMed Central and take full advantage of: Convenient online submission Thorough peer review No space constraints or color figure charges Immediate publication on acceptance Inclusion in PubMed, CAS, Scopus and Google Scholar Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit Beckman Laser Institute and Medical Centre, Irvine, USA Lim et al. Head & Neck Oncology 2010, 2(Suppl 1):O18 http://www.headandneckoncology.org/content/2/S1/O18 © 2010 Lim et al; licensee BioMed Central Ltd.

Methods for evaluating changes in cartilage stiffness following electromechanical reshaping

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ORAL PRESENTATION Open Access

Methods for evaluating changes in cartilagestiffness following electromechanical reshapingAmanda Lim*, Dmitriy Protsenko, Brian Wong

From 2nd Scientific Meeting of the Head and Neck Optical Diagnostics SocietySan Francisco, CA, USA. 23-24 January 2010

One component of several otolaryngological surgeries isthe reshaping of cartilage. Several previous studies havedemonstrated the efficient achievement of this procedurethrough electromechanical reshaping (EMR), a techniquethat involves the direct application of voltage to cartilagemechanically deformed in a jig. Two main parameters,voltage and application time, may be varied to achievevarying degrees of shape change. Both maximized shapechange and minimized intrinsic tissue damage determinethe ideal parameters for EMR. In preceding research,EMR parameters were correlated with degree of shapechange. However, it remains necessary to correlate thesame parameters with the degree of change inthe mechanical properties of tissue. This study satisfiesthis need by providing comprehensive data on the pre-and post-EMR stiffness of both septal and auricularcartilage over a range of voltages with constant applica-tion time (2-8V, 2min, and 2-8V, 3min, respectively).EMR was applied using flat platinum electrodes to one oftwo 15mm X 5mm samples obtained from the same car-tilage specimen, while the second sample was maintainedas a control. Following a 15 min rehydration period, theYoung’s modulus of the tissue was calculated for boththe control and experimental sample from data obtainedthrough a uniaxial tension test. A general reduction instiffness was observed from beginning at 3V, with themagnitude of reduction increasing at 6V.

Published: 29 October 2010

doi:10.1186/1758-3284-2-S1-O18Cite this article as: Lim et al.: Methods for evaluating changes incartilage stiffness following electromechanical reshaping. Head & NeckOncology 2010 2(Suppl 1):O18.

Submit your next manuscript to BioMed Centraland take full advantage of:

• Convenient online submission

• Thorough peer review

• No space constraints or color figure charges

• Immediate publication on acceptance

• Inclusion in PubMed, CAS, Scopus and Google Scholar

• Research which is freely available for redistribution

Submit your manuscript at www.biomedcentral.com/submit

Beckman Laser Institute and Medical Centre, Irvine, USA

Lim et al. Head & Neck Oncology 2010, 2(Suppl 1):O18http://www.headandneckoncology.org/content/2/S1/O18

© 2010 Lim et al; licensee BioMed Central Ltd.