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Mentored Career Development (K) Award Outcomes
National Advisory Council on Drug AbuseFebruary 6, 2008
Lucinda L. Miner, Ph.D.Deputy Director, Office of Science Policy and Communications
National Institute on Drug Abuse
NIDA Dashboard
Medicinal Chemists-- How to facilitate recruitment and training
Medicinal Chemists-- How to facilitate recruitment and training
Collaborations with Other ICs-- How more might be encouragedCollaborations with Other ICs-- How more might be encouraged
??
New PIs-- How they fare in obtaining first R01-- How they fare in obtaining first renewal
New PIs-- How they fare in obtaining first R01-- How they fare in obtaining first renewal
Clinical vs Preclinical Investigators-- How they compare in terms of success
Clinical vs Preclinical Investigators-- How they compare in terms of success
NIDA Dashboard
Medicinal Chemists-- How to facilitate recruitment and training
Medicinal Chemists-- How to facilitate recruitment and training
Collaborations with Other ICs-- How more might be encouragedCollaborations with Other ICs-- How more might be encouraged
??
New PIs-- How they fare in obtaining first R01-- How they fare in obtaining first renewal
New PIs-- How they fare in obtaining first R01-- How they fare in obtaining first renewal
Clinical vs Preclinical Investigators-- How they compare in terms of success
Clinical vs Preclinical Investigators-- How they compare in terms of success
NIDA’S Mentored Career AwardsNIDA’S Mentored Career Awards
K01 - Mentored Research Scientist Development AwardK08 - Mentored Clinical Scientist Development AwardK12 - Mentored Clinical Scientist Development
ProgramProgram AwardK23 - Mentored Patient-Oriented Research Career Development AwardK25 - Mentored Quantitative Research Career Development AwardK99/R00 – Pathway to Independence Award
Mentored K Development AwardsFY 1992-2006
0
20
40
60
80
100
120
140
1601992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
Nu
mb
er
Su
pp
ort
ed
Mentored Career Development (K) Award Outcomes – (K01, K08,
K23)
Awardees Supported in
FY 1999 and 2000
32%18%
50%
0%
10%
20%
30%
40%
50%
60%
MD MD-PhD PhD
Mentored K Awardees by Degree
30%17%
54%
0%
10%
20%
30%
40%
50%
60%
MD MD-PhD PhD
1999
N = 54
2000
N = 78
n = (25) (14) (39)
n = (16) (9) (29)
Current Research Involvement94%
67% 62%
88% 89%79%
13%
33% 31%
0%
20%
40%
60%
80%
100%
University Affiliated With Publications With Funded Grants
1999
Total MDs = 16Total MD-PhDs = 9Total PhDs = 29
2000
Total MDs = 25Total MD-PhDs = 14Total PhDs = 39
(2004-2005) (last yr of K support-2005) (2004-2005)
(2005-2006) (last yr of K support-2006) (2005-2006)
MD MD-PhD PhD
80%
93%85%
96%100%90%
20%
43%
23%
0%
20%
40%
60%
80%
100%
University Affiliated With Publications With Funded Grants
88% 93%79%
44%50% 49%
28%36%
8%20%
29%18%
0%
20%
40%
60%
80%
100%
SubmittedApplications
Funded Funded 1st Try Multiple Awards
Subsequent Funding Activity to 2005/6
75% 78% 76%
38%
56%48%
19%
44%
10%19% 22%
17%
0%
20%
40%
60%
80%
100%
SubmittedApplications
Funded Funded 1st Try Multiple Awards
1999
Total MDs = 16Total MD-PhDs = 9Total PhDs = 29
2000
Total MDs = 25Total MD-PhDs = 14Total PhDs = 39
MD MD-PhD PhD
Subsequent Funding Activity Clinical Research vs Preclinical
2000
Total K01 or K08 Awardees = 69Total K23 Awardees = 9
K01 or K08 K23
80%
100%
49%44%
0%10%20%30%40%50%60%70%80%90%
100%
SubmittedApplications
Funded
10
4
14
01
3
02
01
0
3
0
2
4
6
8
10
12
14
16
NIDA NIMH NINDS NIAAA
Subsequent Funding IC
5 4
8
01
21
0 01 0
3
0
2
4
6
8
10
12
14
16
NIDA NIMH NINDS NIAAA
1999
Total Funded MDs = 6Total Funded MD-PhDs = 5
Total Funded PhDs = 14
2000
Total Funded MDs = 11Total Funded MD-PhDs = 7
Total Funded PhDs = 20
MD MD-PhD PhD
Career Trajectories
Mentored K Development AwardsFY 1992-2006
0
20
40
60
80
100
120
140
1601992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
Nu
mb
er
Su
pp
ort
ed
American Academy of Child and Adolescent Psychiatry
Physician Scientist Program (K12) in Substance Abuse
• Increase the number of child psychiatrists carrying out drug abuse research
• Increase the visibility and presence of drug abuse research in child psychiatry
• Program established in Jan 1998
• First cohort, 1998-2003
• Second cohort, 2005-2009
AACAP-NIDA K12 Program1st Cohort Outcomes
• Seven scholars participated in the first cohort
AACAP-NIDA K12 ProgramAACAP-NIDA K12 Program: : First Cohort Scholar Outcomes as of January 2008First Cohort Scholar Outcomes as of January 2008
Grant Funding
Scholar 1
Scholar 2
Scholar 3
Scholar 4
Scholar 5*
Scholar 6
Scholar 7
Total
NIH Grants Awarded as PI (R level)
1 1 1 1 2 0 0 6
Non-Federal Grant Awards as PI
0 2 0 8 3 1 0 14
NIH Grants Submitted/Under Review as PI
0 0 0 1 1 0 0 2
NIH Grant Support as Co I
1 7 7 7 5 0 0 27
Total Number of Grants
1 PI
1 Co I
3 PI
7 Co I
1 PI
7 Co I
9 PI
7 Co I
5 PI
5 Co I
1 PI
0 Co I
0 PI
0 Co I
20 PI
27 Co I
Data obtained through a self report evaluation requested annually through the AACAP-NIDA K12 Program.
NIH grant data obtained through the CRISP database - January 2008.
AACAP-NIDA K12 Program: Scholar Outcomes as of January 2008
Publications Scholar 1
Scholar 2
Scholar 3
Scholar 4
Scholar 5*
Scholar 6
Scholar 7
Total
1st Authored Publications (Refereed)
10 0 2 11 26 7 0 56
1st Authored Publications (Non-refereed)
3 4 2 3 18 2 0 32
Other Publications
19 12 24 16 29 12 0 112
Total First Authored Publications
13 4 4 14 44 9 0 88
Total Publications
32 16 28 30 73 21 0 200
*All data obtained through a self report evaluation requested annually through the AACAP-NIDA K12.
AACAP-NIDA K12 Program1st Cohort Outcomes
• Five of seven received NIH independent research support within 2 yrs of completing the program
• Four out the five are PI’s on NIDA funded research grants
AACAP- NIDA K12Second Cohort
AACAP-NIDA K12 ProgramAACAP-NIDA K12 Program Second Cohort Second Cohort
Preliminary Outcomes: Publications as of January 2008Preliminary Outcomes: Publications as of January 2008
Publications Scholar 1
Scholar 2
Scholar 3
Scholar 4
Scholar 5
Total
1st Authored Publications (Refereed)
0 4 1 1 1 7
1st Authored Publications (Non-refereed)
4 0 0 0 0 4
Other Publications 3 2 0 0 0 5
Total First Authored Publications to Date
4 4 1 1 1 11
Total Publications to Date
7 6 1 1 1 16
1st Authored Publications Pending/Under Review
2 1 2 0 2 7
AACAP-NIDA K12 ProgramAACAP-NIDA K12 Program Second Cohort Second Cohort
Preliminary Outcomes: Grant Funding as of January 2008Preliminary Outcomes: Grant Funding as of January 2008
Grant Funding
Scholar 1 Scholar 2
Scholar 3
Scholar 4
Scholar 5
Total
NIH Grants Awarded as PI
(R level)
0 0 0 0 0 0
Non-Federal Grant Awards as PI
1 1 0 0 0 2
NIH Grants Submitted/Under Review as PI
0 1 2 1 2 6
Impact on Child Psychiatry
AACAP-NIDA K12 Program: Change in Number of Substance Abuse Related
Research Presentations at the AACAP Annual Meeting
0
10
20
30
40
50
60
70
80
New ReserchPostersSymposia
Other OralPresentations*
*Other Oral Presentations includes Institutes, Workshops and Clinical Perspectives sessions.
First cohort1998-2003
ResearchPresentations
AACAP-NIDA K12 Program: K12 Scholars’ Participation in the
AACAP Annual Meeting
0
2
4
6
8
10
12
Annual Meeting Year
Num
ber
of P
rese
ntat
ions
1st Cohort2nd Cohort
NIDA Dashboard
??Medicinal Chemists--How to facilitate recruitments and training
Collaborations with Other ICs--How more might be encouraged
Clinical vs Preclinical Investigators--How they compare in terms of success
New PIs--How they fare in obtaining first R01--How they fare in obtaining first renewal
Mentored Ks Received vs. Funded (FY 2002-2007)
62
80
128
24
42
27 2734
8279
155
39
0
50
100
150
200
2002 2003 2004 2005 2006 2007
Received Funded
Nu
mb
er o
f K
Ap
pli
can
ts
Mentored Ks by Degree K01, K08, K23
0
20
40
60
80
100
120
2001 2002 2003 2004 2005 2006 2007
MDs
MD-PhDs
PhDs/ODs
Nu
mb
er
Su
pp
ort
ed
Mentored K Success Rates by Degree (K01, K08, K23)
0
10
20
30
40
50
60
70
80
90
100
2001 2002 2003 2004 2005 2006 2007
MDs
MD-PhDs
PhDs/ODs
Nu
mb
er
Su
pp
ort
ed
8% 7%
30% 30%
55%
73%
25%20%
48% 46%
61%
82%
0%
20%
40%
60%
80%
100%
Success Rates of R01-Equivalent Applications (FY 2007)
NEW
NIH NIDA
COMPETING CONTINUATION
Original A1 A2 Original A1 A2
27 24 28 2621
27
105
11 12 813 12 11 12 12 17
10
0
20
40
60
80
100
36 33 38 38
13
4531 33 31
26 27 2533
2236
2819
32
0
20
40
60
80
100
Original Applications
1st Amendments (A1)
Su
cces
s R
ate
(%)
Su
cces
s R
ate
(%)
OverallNew Investigator Non-New Investigator
75 6780
50
67
45
75
100
6758
5060
3743
33
61
0
69
0
20
40
60
80
100
2002 2003 2004 2005 2006 2007
2nd Amendments (A2)
Su
cces
s R
ate
(%)
