Medicine, Nursing and Health Sciences

Your Infrastructure:-Choosing & Using Your Guidelines

Getting Started With Your

Systematic Review

A Workshop by:-

Kendall Searle

Josefine Antoniades

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HOW? A collaborative workshop format!

This work shop will help you to:-

1. Refine your research question

2. Give you feedback on your research question

3. Give you search-strategy leads

4. Provide some infrastructure to facilitate a systematic approach

5. Give practical time-saving tips

6. Reflect a student’s real learning!

This work shop will not address:-

1. The different syntax used for different search engines (Anne Young)

2. Concepts concerning bias

3. The tools needed to appraise the quality of your articles

4. Key analysis approaches e.g.: narrative and meta analysis

These will be covered in forthcoming workshops!

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How we are going to divide our time:-

Managing the Panic:-Putting order into the

overall task!

Defining the Question With PICOS:-

Time for a lucky dip!

Musical Graffiti!When scientists must

be linguists too!

Good enough to repeat!Can someone else

follow your route map?

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Every Body Panic Now!

You have to do a SYSTEMATIC what??!!

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Exercise One: Everybody Panic Now!

Arrange yourselves into groups

Each group to receive one envelope

Inside each envelope you will find a set of phrases

You have five minutes to read each of the phrases in turn and then place them in a logical order

Once you have decided your order, use the blue-tack to stick them up on the white-board.

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After the Panic Comes Order! What do you notice about the orders?

Where have you seen these statements before?

What is the gold standard approach?

How does the gold standard differ from the average student experience?

If you are time and resource poor, which steps might you cut out?

– What is the consequence of this?

What other steps, if any, would you add?

See Hand Out: Exercise 1:Everybody Panic Now

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13 August 2014Systematic Reviews

http://www.prisma-statement.org/2.1.2%20-%20PRISMA%202009%20Checklist.pdf

13 August 2014Systematic Reviews

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What is a Systematic Review?

A trusty route map!

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Top Tips from a Newly Initiated Student

Infrastructure is your Protocol. A plan for resource allocation!

Infrastructure avoids bias!

Infrastructure helps you to manage your supervisor and collaborators – and look good!

Infrastructure aids writing up by giving you personal targets

Infrastructure makes analysis quick and easy!

Even the greatest of works needed infrastructure to aid the making!

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Facilitate Your Briefing With An Easy to Use List:-

Source: Common mental disorder among factory workers in mainland China:- a systematic review by Kendall Searle

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YOUR PRISMA FLOW CHART

Don’t be shy about writing it up as you

go along.

Use it as a reward system for yourself!

It keeps track of your work and needs

to be included in your final paper

anyway!

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Maximise on End Note As A Site to:-

Download each of your database searches

Deal with duplicates

Record each of your screening steps

Code your screen-outs

Build a PDF resource

Write-up with citations

Source: Common Mental Disorders Amongst Migrant/Factory Workers in Mainland China: Coding in Progress

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Which Guide For You?PRISMA Preferred Reporting Items for Systematic reviews and Meta-analyses (2009)

Handy PICOS to help frame your question

Covers non-randomised studies to assess the benefits and harms of interventions

Can be modified for diagnosis or prognosis

27-point check list

CONSORT 2010Consolidated Standards of Reporting Trials (1996)

Initial scope covers two-armed, parallel, randomized, controlled trials

Extensions for non-inferiority, equivalence, factorial, cluster, crossover trials

25-point check list (but lots of a’s and b’s!)

Reporting of funding & ethics advised but not in check list

Institute of Medicine, USAwww.iom.edu/Reports/2011/Finding-What-Works-in-Health-Care-Standards-for-Systematic-Reviews.aspx

Emphasizes team approach

Itemizes conflict of interest and funding concerns

Considers qualitative alongside quantitative review

Divides standards into 4 activity groups

Clear, complete and transparent reporting of trial information to provide an unbiased evidence-base for decision making

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PICOS:- Frames your research interest to improve the explicitness of your review question

PICOS

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PICOS:- Frames your research interest to improve the explicitness of your review question

ParticipantsThe patient population or disease being addressed

ICOS

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PICOS:- Frames your research interest to improve the explicitness of your review question

ParticipantsThe patient population or disease being addressed

InterventionsThe interventions or exposure of interest

COS

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PICOS:- Frames your research interest to improve the explicitness of your review question

ParticipantsThe patient population or disease being addressed

InterventionsThe interventions or exposure of interest

ComparisonsThe comparators

OS

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PICOS:- Frames your research interest to improve the explicitness of your review question

ParticipantsThe patient population or disease being addressed

InterventionsThe interventions or exposure of interest

ComparisonsThe comparators

OutcomesThe main outcome or endpoint of interest

S

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PICOS:- Frames your research interest to improve the explicitness of your review question

ParticipantsThe patient population or disease being addressed

InterventionsThe interventions or exposure of interest

ComparisonsThe comparators

OutcomesThe main outcome or endpoint of interest

Study designThe study designs chosen

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Refining Your Research Question A student case study

Common Mental Disorders

amongst Migrants/Factory Workers

in Mainland China

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PICOS:- Frames your research interest to improve the explicitness of your review question

ParticipantsThe patient population or disease being addressed

Factory workers in main-land China

InterventionsThe interventions or exposure of interest

Internationally recognized diagnostic and screening tools which measure common mental health disorders and quality-of-life

ComparisonsThe comparators Non-factory workers, Urban

and rural counter-parts

OutcomesThe main outcome or endpoint of interest

Common mental disorders;Quality-of-life

Study designThe study designs chosen

Will consider a range of study types (e.g. Cross-sectional)

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Important Websites The Cochrane Handbook for Systematic Reviews of Interventions

www.cochrane.org/handbook

PRISMA Transparent reporting of systematic reviews and meta-analyses http://www.prisma-statement.org/

Institute of Medicine, USA. Finding What Works in Health Care: Standards for Systematic Reviews www.iom.edu/Reports/2011/Finding-What-Works-in-Health-Care-Standards-for-Systematic-Reviews.aspx

International prospective register of systematic reviews (PROSPERO) http://www.crd.york.ac.uk/PROSPERO