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Medical Education 4 7 1 Ohm’s Law Energy Disclaimer 5 8 2 Device Function Sensing Objectives Stimulation Threshold 6 9 3 Overview Questions Fundamentals of Pacing Therapy Electrical Terms and Concepts

Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

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Page 1: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

Medical Education

4 71 Ohm’s Law EnergyDisclaimer

5 82 Device Function SensingObjectives

StimulationThreshold

6 93 Overview Questions

Fundamentals of Pacing Therapy

Electrical Terms and Concepts

Page 2: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

2 ©2007 Boston Scientific Corporation

Medical Education

Disclaimer

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

This presentation is provided with the understanding that the slide content must not be altered in any manner as the content is subject to FDA regulations.

This presentation is to be used in conjunction with other resource material including the applicable Boston Scientific device physician’s manual and any implant accessories instructions for use.

This presentation is not intended to replace implant training.

Proper surgical procedures and techniques are the responsibilities of the medical professional.

If this presentation is not used in its entirety, the following information must be included:

• Appropriate Indications

• Contraindications

• Warnings

• Precautions and Adverse Events

Page 3: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

3 ©2007 Boston Scientific Corporation

Medical Education

Objectives

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Define basic electrical terms

Explain how these terms relate to device function

Discuss the relationship between voltage, current, and resistance

Define stimulation threshold and factors affecting it

Explain pacemaker sensing and factors affecting it

When we complete this program you will be able to:

Page 4: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

4 ©2007 Boston Scientific Corporation

Medical Education

Overview

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Ohm’s Law• Voltage

• Current

• Impedance

Energy

Stimulation Threshold

Sensing• Slew Rate

Electrical Terms and Concepts:

Page 5: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

5 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s Law

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Ohm’s Law: V = I x R

Describes the relationship between voltage, current, resistance: V = I x R; I = V/R; R = V/I

Voltage The electrical force that makes current move through a conductor – measured in volts (V)

Impedance The total opposition presented to the flow of current by an electrical circuit or device –measured in ohms (R)

Current The transfer of electrical charge (electrons) through a cross-section of a conductor –measured in amperes (I)

Page 6: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

6 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s Law

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

The force or “push” that causes electrons to move through a circuit

Measured in volts

Represented by the letter “V”

Often referred to as amplitude

Voltage:

Page 7: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

7 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s Law

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Current:

The flow of electrons in a completed circuit

Measured in mA (milliamps)

Represented by the letter “I”

Page 8: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

8 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s Law

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Impedance:

The opposition to current flow

Measured in ohms

Represented by the letter “R” (W for numerical values)

Often referred to as resistance

Page 9: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

9 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s LawCan Be Used to Find Current

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Example 1:

Voltage = 5 V

Impedance = 500 Ω

What will the current be?

I = V/R 5 V ÷ 500 Ω = 0.010 Amperes x 1000 = 10 mA

Page 10: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

10 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s LawCan Be Used to Find Current

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Example 2:

Voltage = 2.5 V

Impedance = 500 Ω

What will the current be?

I = V/R 2.5 V ÷ 500 Ω = 0.005 Amperes 0.005 x 1000 = 5 mA

Page 11: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

11 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s LawCan Be Used to Find Current

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Example 3:

Voltage = 5 V

Impedance = 250 Ω

What will the current be?

I = V/R 5 V ÷ 250 Ω = 0.020 Amperes 0.020 x 1000 = 20 mA

Page 12: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

12 ©2007 Boston Scientific Corporation

Medical Education

Ohm’s LawElectrical Analogy

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Voltage = Current x Resistance

“Normal” Resistance

“Low” Resistance

“High” Resistance

“Normal”Current

“High”Current

“Low”Current

Current is similar to the flow of water

Voltage is analogous to water pressure

Resistance can be compared to resistance to flow

Page 13: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

13 ©2007 Boston Scientific Corporation

Medical Education

Device FunctionInsulation Break

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Current is Escaping:

Decreased Resistance

Increased Current Drain

Increased Energy Usage

Page 14: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

14 ©2007 Boston Scientific Corporation

Medical Education

Device FunctionLead Fracture

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Current Cannot Reach Heart:

Increased Resistance

Decreased Current Drain

Decreased Energy Usage

Page 15: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

15 ©2007 Boston Scientific Corporation

Medical Education

Device FunctionHigh Impedance Leads

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Reducing Electrode Size:

Increases impedance

Decreases current drain

Increases longevity

Smaller current drainLarger current drain

Page 16: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

16 ©2007 Boston Scientific Corporation

Medical Education

Device FunctionImpedance

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

High Impedance

Decreases battery current drain, increases longevity

Low Impedance

Increases battery current drain, decreases longevity

Page 17: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

17 ©2007 Boston Scientific Corporation

Medical Education

Device FunctionConstant Voltage Pacemakers

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

V = IR

V = IR

Page 18: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

18 ©2007 Boston Scientific Corporation

Medical Education

Stimulation Threshold

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Definition:

The minimum electrical stimulus needed to consistently capture the heart outside of the heart’s refractory period

Page 19: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

19 ©2007 Boston Scientific Corporation

Medical Education

Stimulation ThresholdPulse Amplitude

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

The voltage delivered by the electrical pacingstimulus (volts)

Amplitude

Pacing Pulse

Page 20: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

20 ©2007 Boston Scientific Corporation

Medical Education

Stimulation ThresholdPulse Width

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Pacing Pulse

Pulse Width

Duration of the electrical pacing pulse (milliseconds)

Page 21: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

21 ©2007 Boston Scientific Corporation

Medical Education

Stimulation Threshold

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Amplitude (V) + Pulse Width (ms) = Output

Lowest Output that Captures Outside of Refractory = Threshold

Page 22: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

22 ©2007 Boston Scientific Corporation

Medical Education

Stimulation Threshold

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Why Measure?

Assure proper lead placement

Determine safety margin

Page 23: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

23 ©2007 Boston Scientific Corporation

Medical Education

Stimulation Threshold

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Affected by:

Lead Maturation

Lead Technology

Medications

Lead Location

Page 24: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

24 ©2007 Boston Scientific Corporation

Medical Education

Stimulation ThresholdLead Maturation

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Chronic Electrode:

Excitable Tissue

Non-Excitable Fibrotic Tissue

Virtual Electrode

Electrode

Page 25: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

25 ©2007 Boston Scientific Corporation

Medical Education

Stimulation ThresholdsEffect of Steroid

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Pulse Width = 0.5 msec

0

3 6

Implant Time (Weeks)

Non-steroid

1

2

3

4

5

Steroid/IROX Electrode

0 1 2 4 5 7 8 9 10 11 12

Pu

lse W

idth

(m

s)

S. Furman, D. Hayes, D Holmes; “A Practice of Cardiac Pacing” 2nd Revision, 1989; p.36

Page 26: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

26 ©2007 Boston Scientific Corporation

Medical Education

Stimulation ThresholdStrength Duration Curve

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Capture

Noncapture

1.0Pulse Width (ms)

Pulse Amplitude

Page 27: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

27 ©2007 Boston Scientific Corporation

Medical Education

Stimulation ThresholdStrength Duration Curve

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions Pulse Width (ms)

Voltage StimulationThreshold (Volts)

2.0

1.5

1.0

.50

.40

.25

0.5 1.0 1.5 2.0 2.5 3.0

Page 28: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

28 ©2007 Boston Scientific Corporation

Medical Education

Energy

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

V2 TE =

R

E = Energy

V = Voltage

T = Time

R = Resistance

Page 29: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

29 ©2007 Boston Scientific Corporation

Medical Education

Energy

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

2x Voltage = 4x Energy

2x Pulse Width = 2x Energy

Page 30: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

30 ©2007 Boston Scientific Corporation

Medical Education

Energy

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

5.02 (.50ms)25 µJ

500

Page 31: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

31 ©2007 Boston Scientific Corporation

Medical Education

Energy

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

2.52 (.50ms)6.25 µJ

500

Page 32: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

32 ©2007 Boston Scientific Corporation

Medical Education

Energy

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

5.02 (.25ms)12.5 µJ

500

Page 33: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

33 ©2007 Boston Scientific Corporation

Medical Education

Sensing

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Definition:

Sensing is the ability of the pacemaker to “see” when an intrinsic depolarization is occurring

Page 34: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

34 ©2007 Boston Scientific Corporation

Medical Education

Sensing

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Accurate sensing requires filtering out extraneous signals

Unwanted signals include:

T-waves

Far-field events

Myopotentials

Page 35: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

35 ©2007 Boston Scientific Corporation

Medical Education

Sensing

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Electrophysiological properties of the myocardium

Characteristics of the electrode

Lead placement

Sensing amplifiers of the pacemaker

Lead polarity

Lead integrity

EMI

Sensing may be affected by:

Page 36: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

36 ©2007 Boston Scientific Corporation

Medical Education

Sensing

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Review of Sensitivity:

1.0mV

4.0mV

2.0mV

*programmed sensitivity

*

Page 37: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

37 ©2007 Boston Scientific Corporation

Medical Education

Sensing

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Review of Sensitivity:

1.0mV

4.0mV

2.0mV

Programming a higher setting decreases the sensitivity of the device – fewer signals are sensed

Page 38: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

38 ©2007 Boston Scientific Corporation

Medical Education

Sensing

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Review of Sensitivity:

1.0mV

4.0mV

2.0mV

Programming a lower setting increases the sensitivity of the device – more signals are sensed

Page 39: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

39 ©2007 Boston Scientific Corporation

Medical Education

Sensing

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions

Slew Rate:

∆ V / Time = Slew Rate

Page 40: Medical Education Fundamentals of Pacing Therapy · Device Function Impedance Electrical Terms and Concepts Disclaimer Objectives Overview Ohm’s Law Device Function Stimulation

40 ©2007 Boston Scientific Corporation

Medical Education

Questions

Electrical Terms and Concepts

Disclaimer

Objectives

Overview

Ohm’s Law

Device Function

Stimulation Threshold

Energy

Sensing

Questions