MBV2010/BIO2140

Colloquium, February 5

RULES

• Multiple choice• Only one correct answer• 30-60 seconds to answer• No textbook, computer, mobile phone, please

There will be a prize for the group with the most correct answers.

Example

4789 x 9548 = ??

A 44 877 267

B 42 872 186

C 45 725 372

D 49 693 726

0

Example

4789 x 9548 = ??

A 44 877 267

B 42 872 186

C 45 725 372

D 49 693 726

0

Nucleic acids were first isolated in the …

A 17th century

B 18th century

C 19th century

D 20th century

1

Nucleic acids were first isolated in the …

A 17th century

B 18th century

C 19th century (1869)

D 20th century

1

Friedrich Miescher

The major form of DNA in cells is …

A A-DNA

B B-DNA

C C-DNA

D Z-DNA

2

The major form of DNA in cells is …

A A-DNA

B B-DNA

C C-DNA

D Z-DNA

2

A A-DNA

B B-DNA

C C-DNA

D Z-DNA

3Which form of DNA is shown here ?

A A-DNA

B B-DNA

C C-DNA

D Z-DNA

3Which form of DNA is shown here ?

Most RNA in cells is …

A messenger RNA

B transfer RNA

C micro RNA

D ribosomal RNA

4

Most RNA in cells is …

A messenger RNA

B transfer RNA

C micro RNA

D ribosomal RNA

4

Transcriptomes consist of …

A messenger RNA

B transfer RNA

C ribosomal RNA

D all of the above

5

Transcriptomes consist of …

A messenger RNA

B transfer RNA

C ribosomal RNA

D all of the above

5

The genetic code

A consists of 62 codons

B has 3 stop codons

C is used in transcription

D specifies 25 amino acids

6

The genetic code

A consists of 62 codons

B has 3 stop codons

C is used in transcription

D specifies 25 amino acids

6

Restriction endonucleases

A are located in the nucleus of cells

B are sequence-specific

C were discovered in the 1980s

D are present in bacteria and fungi

7

Restriction endonucleases

A are located in the nucleus of cells

B are sequence-specific

C were discovered in the 1980s

D are present in bacteria and fungi

7

Which compound is not found in nucleic acids?

A Pyridines

B Purines

C Phosphate

D Ribose

8

Which compound is not found in nucleic acids?

A Pyridines

B Purines

C Phosphate

D Ribose

8

Pyridine Pyrimidine

The secondary structure of proteinsis stabilized by …

A Ionic bonds

B Hydrogen bonds

C Disulfide bonds

D Hydrophobic interactions

9

The secondary structure of proteinsis stabilized by …

A Ionic bonds

B Hydrogen bonds

C Disulfide bonds

D Hydrophobic interactions

9

DNA polymerases

A synthesize DNA in 3’ -> 5’ direction

B require a primer to initiate DNA

synthesis

C require ATP

D bind only to DNA

10

DNA polymerases

A synthesize DNA in 3’ -> 5’ direction

B require a primer to initiate DNA

synthesis

C require ATP

D bind only to DNA

10

The human nuclear genome …

A is split into 24 chromosomes

B Is the largest genome known to date

C Contains about 2 billion bp

D Contains about 40,000 genes

11

The human nuclear genome …

A is split into 24 chromosomes

B Is the largest genome known to date

C Contains about 2 billion bp

D Contains about 40,000 genes

11

Human female karyogram

Reverse transcriptases

A Synthesize RNA

B Use DNA as template

C Are viral enzymes

D Are present in all eukaryotic cells

12

Reverse transcriptases

A Synthesize RNA

B Use DNA as template

C Are viral enzymes

D Are present in all eukaryotic cells

12

ORF scanning

A is used to find intron sequences

B is used to find functional genes

C is used to identify protein-coding

genes

D is used to find intergenic sequences

13

ORF scanning

A is used to find intron sequences

B is used to find functional genes

C is used to identify protein-coding

genes

D is used to find intergenic sequences

13

A codon bias …

A is present in intergenic regions of a

genome

B is used to find protein- coding genes

C is only present in

eukaryotic genomes

D has been found for all codons

14

A codon bias …

A is present in intergenic regions of a

genome

B is used to find protein- coding genes

C is only present in

eukaryotic genomes

D has been found for all codons

14

Expression of genes can be analyzed by

A northern analysis

B Southern analysis

C Comparative genomics

D PCR

15

Expression of genes can be analyzed by

A northern analysis

B Southern analysis

C Comparative genomics

D PCR

15

An alpha-helix

A is a DNA structure

B is a protein structure

C winds to the left

D is stabilized by base stacking

16

An alpha-helix

A is a DNA structure

B is a protein structure

C winds to the left

D is stabilized by base stacking

16

ß-sheets are stabilized by

A hydrophobic bonds

B ionic bonds

C hydrogen bonds

D all of the above

17

ß-sheets are stabilized by

A hydrophobic bonds

B ionic bonds

C hydrogen bonds

D all of the above

17