Mastering the coeliac condition: from medicine to social sciences and food technology

Florence, 29-31 March 2012

Thursday

29Friday30 Saturday31

Morning

//

InternationalMeeting:TheNew

FrontiersofCoeliacDisease:anUpdatefromBasictoClinical

Research

SessionA

ConventionforFoodIndustry

SessionB

Coeliacdisease:nutritionalqualitybeyondfoodsafety

SessionC

Coeliacdiseaseis

recognisedasasocialdisease”:

whatdoesitmean?

SessionD

YoungReserchers

Afternoon

InternationalMeeting:TheNew

FrontiersofCoeliac

Disease:anUpdate

fromBasictoClinicalResearch

InternationalMeeting:TheNew

FrontiersofCoeliacDisease:anUpdatefromBasictoClinical

Research

Thescientificconference“insmalldoses"forAIC'smembers

“The New Frontiers of Coeliac disease:

an Update from Basic to Clinical Research” 29-30 March 2012

PRELIMINARY PROGRAMME

Thursday,29March

14.00 Registrationofparticipants

14.45 IntroductionE.Tosi,UVolta

Session1:Pathogenesisofcoeliacdisease:what’snew?Chiarmen:G.R.Corazza,P.Lionetti15.00NewknowledgeaboutgeneticsandtoxicityofcerealsN.E.Pogna 15.20 Tissue‐mediatedcontrolofimmunopathologyincoeliacdisease L.Sollid15.40 Wheatamylase‐trypsininhibitors asdriversofinnateimmunityincoeliacdisease D.Schuppan16.00Animalmodelsofcoeliacdisease

B.Jabri

16.20 Generaldiscussion16.50 CoffeebreakSession2:Genetics:improvementofknowledgeandpracticalimplicationsChiarmen:S.Auricchio,M.T.Bardella

17.15 Exploringsharedgeneticlinkageandautoimmunitybetweencoeliacdiseaseandtype1diabetesmellitus

E.J.Hoffenberg17.35 HLA‐relatedgeneticriskforcoeliacdiseaseinfirst‐degreerelativesofcoeliac patients L.Greco17.55 Geneticsandriskforassociatedautoimmunedisordersandrefractorycoeliac disease C.Wijmenga

18.15 RecommendationsforperformanceandinterpretationoftheHLAtestfor

coeliacdiseaseinItaly(adocumentapprovedbyCSN‐AIC,SIGUandAIBT) M.C.Mazzilli

18.35 GeneralDiscussionFriday,30MarchSession3:NewtrendsinclinicalaspectsofcoeliacdiseaseChiarmen:E.Cardi,G.Gasbarrini 9.15 HowtheclinicalpresentationofcoeliacdiseasehaschangedS.Guandalini

9.35 Potentialcoeliacdisease:needforshareddiagnosisandmanagementprotocolsR.Troncone

9.55 Hyposplenismasariskfactorofinfection,autoimmunityandcomplicationin coeliacdiseaseA.DiSabatino

10.15 Wheat‐induceddisordersbesidescoeliacdisease:nonceliacglutenintolerance (gluten‐sensitivity)andwheatallergy K.Kaukinen

10.35 Generaldiscussion

11.05 Coffeebreak Session4:Diagnosticcriteria:somethingischangingChiarmen:U.Volta,B.Malamisura

11.30 PitfallsofthemorphologicalevaluationV.Villanacci11.50 Deamidatedgliadinantibodiesandothernewantibodytests:aretheyastep

forwardforcoeliacdiseasediagnosis?I.Korponay‐Szabo

12.10 ThenewESPGHANproposalforcoeliacdiseasediagnosisS.Husby

12.40 Generaldiscussion

13.10 Lunch

Session5:Roundtableon“Perspectivesforanalternativetreatmenttogluten‐freediet” Chiarmen:A.Calabrò,G.Iacono,M.Silano15.00 Degradationofimmunogenicglutenpeptidesbysourdoughlactobacilli proteases:howtoobtainbakedgoodsofwheatfloursafeforcoeliacs M.Gobbetti

15.15 “Invivo”digestionofglutenbymeansofbacterialandfungalprolyl‐ endopeptidases

F.Koning

15.30 Updateonthevalidationandonthepracticaluseofthezonulin‐inhibitordrug A.Fasano

15.45 Vaccinationforcoeliacdisease:uthopyorconcretehopeforcoeliacdisease recovery R.P.Anderson

16.00 RoleofIL‐15incoeliacdisease‐associatedinflammationandlymphomagenesis anditstherapeuticimplication G.Malamut16.15 RoleofIL‐21inmodulatingtheinflammationincoeliacdiseaseandits therapeuticimplication G.Monteleone

16.30 RoleofIL‐10andT‐reglymphocytesandtheirtherapeuticalimplication C.Gianfrani

16.45 AutologousbonemarrowtransplantationintypeIIrefractoryCDunresponsive tocladribineandotherpharmacologicaltherapy C.Mulder

17.00 Generaldiscussion

17.30 Coffeebreak

Session6:ResearchProjectsofCoeliacdiseaseFoundationChiarmen:I.DeVitis,GGuariso17.50 Complicationsofcoeliacdisease G.R.Corazza

18.10 Preventionofcoeliacdisease C.Catassi

18.30 Generaldiscussion18.45 EvaluationtestforItalianparticipants19.00 Endofthemeeting

PresidentoftheMeetingUmbertoVoltaDepartmentofGastroenterologyandInternalMedicineS.OrsolaMalpighiHospital,UniversityofBolognaBologna,ItalyVicePresidentsoftheMeetingAntonioCalabròDepartmentofGastroenterologyUniversityofFlorence–CareggiHospitalFlorence,ItalyCarloCatassiDepartmentofPediatrics,UniversitàPolitecnicadelleMarcheAncona,ItalyCenterForCeliacResearchUniversityofMarylandSchoolofMedicineBaltimore,USAHonoraryPresidentsSalvatoreAuricchioDepartmentofPediatricsandEuropeanLaboratoryfortheInvestigationofFood‐InducedDiseasesUniversityFedericoIINaples,ItalyEttoreCardiInstituteofPediatricsSapienzaUniversityRome,ItalyGinoR.CorazzaFirstDepartmentofMedicinePoliclinicoS.Matteo,UniversityofPaviaPavia,ItalyScientificCommitteeMariaTeresaBardellaCenterforPreventionandDiagnosisofCoeliacdiseaseMaggioreHospital‐IRCCSPoliclinicoMilan,Italy

AntonioCalabròDepartmentofGastroenterologyUniversityofFlorence–CareggiHospitalFlorence,ItalyCarloCatassiDepartmentofPediatrics,UniversitàPolitecnicadelleMarcheAncona,ItalyCenterForCeliacResearchUniversityofMarylandSchoolofMedicineBaltimore,USAEttoreCardiInstituteofPediatricsSapienzaUniversityRome,ItalyAminaCiampellaFoodTechnologistGenova,ItalyIreneGiuliaCimmaPsychologistAreSSPiemonteAICPiemonte–Valled’AostaTurin,ItalyCostantinoCipollaPresidentResearchCentreofadvancedstudiesonpatients’dignityrespectandsocialwelfareBologna,ItalyItaloDeVitisGastroenterologyUnitUniversitàCattolicadelSacroCuoreRome,ItalyGraziellaGuarisoDepartmentofPediatryUniversityofPadovaPadova,ItalyGiuseppeIaconoDivisionofPediatricGastroenterologyDiCristinaChildren'sHospitalPalermo,Italy

PaoloLionettiDepartmentofPediatrics"CesareCocchi"MeyerChildren'sHospital,UniversityofFlorenceFlorence,ItalyBasilioMalamisuraRegionalreferencecenterforcoeliacdiseaseDepartmentofPediatricsHospitalUniversityofSalernoCavade'Tirreni(NA),ItalyMarcoSilanoDepartmentofFoodSciences,HumanNutritionandHealthIstitutoSuperiorediSanitàRoma,ItalyUmbertoVoltaDepartmentofGastroenterologyandInternalMedicineS.OrsolaMalpighiHospital,UniversityofBolognaBologna,ItalyOrganizingCommittee CletoCorposantoManagerofItalianCoeliacAssociationMonitoringUnitTrento,ItalyCaterinaPiloGeneralManagerItalianCoeliacAssociationGenoa,ItalyAdrianoPucciPresidentofCoealiacFoundationFlorence,ItalyElisabettaTosiPresidentofItalianCoeliacAssociationFlorence,Italy RossellaValmaranaConsultantFoodAreaItalianCoeliacAssociationMilano,Italy

SpeakersandchairmenRobertAndersonAutoimmunityandTransplantationDivisionWalterandElizaHallInstituteandDepartmentofGastroenterologyTheRoyalMelbourneHospitalMelbourne,Victoria,AustraliaAntonioDiSabatinoFirstDepartmentofMedicinePoliclinicoS.Matteo,UniversityofPaviaPavia,ItalyAlessioFasanoMucosalBiologyResearchCenterUniversityofMarylandSchoolofMedicineBaltimore,USAGiovanniGasbarriniDepartmentofInternalMedicinePoliclinico"A.Gemelli"‐CatholicUniversityRome,ItalyCarmenGianfraniUnitofImmunobiology(IBG)InstituteofFoodScience‐CNRAvellino,ItalyMarcoGobbettiDepartmentofPlantProtectionandAppliedMicrobiologyUniversityofBariBari,ItalyLuigiGrecoDepartmentofPediatricsandEuropeanLaboratoryfortheInvestigationofFood‐InducedDiseasesUniversityFedericoIINaples,ItalyStefanoGuandaliniPediatricGastroenterology,Hepatology,andNutritionUniversityofChicagoCeliacDiseaseCenterChicago,USA

Edward J. Hoffenberg Section of Gastroenterology, Hepatology and Nutrition Department of Pediatrics The Children's Hospital University of Colorado Denver, Usa SteffenHusbyHans Christian Andersen Children's Hospital Odense University Hospital Odense,DenmarkBanaJabriDigestiveDiseaseResearchCoreCenterUniversityofChicagoUsaKatriKaukinenMedicalSchoolUniversityofTampereTampere,FinlandFritsKöningDepartmentofImmunohematologyandBloodTransfusionUniversityMedicalCenterLeiden,TheNetherlandsIlmaRitaKorponay‐SzaboDepartmentofPediatricsMedicalandHealthScienceCenterUniversityofDebrecen,HungaryGeorgiaMalamutHepatologyandGastroenterologyDepartmentHôpitalEuropéenGeorgesPompidou,UniversitéParisDescartes,InsermParis,FranceMariaCristinaMazzilliDepartmentofMolecularMedicineSapienzaUniversityRome,ItalyGiovanniMonteleoneDepartmentofInternalMedicineUniversityTorVergataRome,Italy

ChrisMulderDepartmentofGastroenterologyUniversityofAmsterdamAmsterdam,TheNetherlandsNorbertoE.PognaResearchUnitforFoodandNutritionCRA(CerealFarmingResearchInstitute)Rome,ItalyDetlefSchuppanDepartmentofInternalMedicineUniversityofMainzMainz,GermanyLudwigSollidInstituteofImmunologyCentreforImmuneRegulationUniversityofOsloOslo,NorwayRiccardoTronconeDepartmentofPediatricsandEuropeanlaboratoryfortheInvestigationofFoodInducedDiseasesUniversityFedericoIINaples,ItalyVincenzoVillanacciAnatomicalPatologySpedaliCiviliBresciaHospitalBrecia,ItalyCiscaWijmengaGeneticsDepartment,UniversityMedicalCenterGroningen,TheNetherlands

PARALLELSESSIONS30‐31March

SessionAConventionforFoodIndustryFriday,30March11:00–16:30An exhaustive picture of in force rules on gluten‐free production in Italiy and abroad will beoutlined in this session. AIC's activities aimed to provide information and support to coeliacconsumerswillbepresented,witha focuson“SpigaBarrata”brand, thattoday is releasedwiththesamestandardsinallEuropencountries.Discussionaboutthemarket,aparticularconsumerastheCoeliacone,andmarketingappliedtogluten‐freediet.SessionB Coeliacdisease:nutritionalqualitybeyondfoodsafetySaturday,31March9:00–13:30Two topics for gluten‐free diet: at home and out. Some time ago production was focused ongluten‐freerequirement,buttodaynutritionalquality ismoreandmore importantandCoeliacs'expectations go beyond gluten‐free products. Is enough attention paid to gluten‐free productquality?DoesPublicHealthfacethisproblem?How?Thissessionfocusonfood'squality,butalsoon the enforcement of food safety to industry and catering, in order to inform and increasesensibilitytothesetopics.SessionCArt1,L.123/05“Coeliacdiseaseisrecognisedasasocialdisease”:whatdoesitmean?Saturday,31March9:00–13:30Thearticlen.1ofL.123/05definecoeliacdiseaseasasocialdisease.Butwhatistherealmeaningof it?Whichisthesocial impactofadiseasethat influencesthewayoffeeding?Howcansocialinfluenceaffect thechoiceofgoingonagluten‐freediet?Psychosocialsciencesexpertswonderabout coeliac disease's impact on relationships, on everyday life, on social relations. Focus onconcerning aspects of adherence to gluten‐free diet and of its voluntary violation or even itsrefusal.SessionD YoungresearchersSaturday,31March9:00–13:30Young researchers will take the floor: in the last years they got noticed in the internationalscientificcommunity.CoeliacdiseasehasnewresearchersandCoeliacshavenew“allies”.Thescientificconference“insmalldoses”forAIC'smembersSaturday,31March14:00–18:00Bytradition,closingthisscientificinitiative,themainSpeakerswillsumupalllecturestothewidetargetofAIC'smembers,whoreachFlorencefromeverypartofItaly.

[Meetingvenue]

PalazzodegliAffari–PalazzodeiCongressiPiazzaAdua1Firenze[OrganizingSecretariat]

ForumServiceViaMartinPiaggio17/616122Genova

RegistrationandhotelbookingTel003901083794235Fax003901083794261symposium@celiachia.it