Technical Brief

Managing Patients with Positive E.R.D.-HealthScreen® Tests

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For questions please call Heska’s Support Services at 1-800-GO HESKA, option 5.

Order# 249222 0206

Spot Color

Build Color

2623 Spot / 450 Build

Black

Reverse

Spot Color

Build Color

2623 Spot / 450 Build

Black

Reverse

UNDERLYING CONDITIONNOT FOUND

UNDERLYING CONDITIONFOUND

1. Monitor patient every 6 – 12 months (e.g., physical examination, urinalysis + Canine/Feline E.R.D.-HealthScreen®

Urine Test, serum creatinine)

2. Prevent inflammatory, infectious and/or metabolic diseases that could contribute to kidney damage*

3. Treat dehydration aggressively with intravenous fluids†

4. Provide hemodynamic support with intravenous fluids during anesthesia

5. Use potentially nephrotoxic drugs judiciously and increase monitoring of animals that require therapy with these compounds

Treat Underlying Condition

Repeat E.R.D.-HealthScreen®

Test to Monitor Treatment(e.g., 4 weeks post-Tx)

E.R.D.-HealthScreen® Test = Low – Medium Positive

E.R.D.-HealthScreen® Result= High – Very High Positive

Determine Microalbuminuria TrendRepeat E.R.D.-HealthScreen® Test

(2x at a 1 – 3 month interval)

Urine Protein:Creatinine RatioOr

Quantitative Microalbuminuria TestEstablish Baseline and Monitor

MICROALBUMINURIAINCREASING

Initial Diagnostic Work-up May Include:Complete Blood Count, Serum Chemistry Panel, Blood Pressure Measurement

Initial Diagnostic Workup Should Include:Physical Examination and Urinalysis

MICROALBUMINURIASTABLE OR DECREASINGRecommendations

for Managing the Microalbuminuric Patient

Determine Microalbuminuria Trend

1. Monitor patient every 3 – 6 months (e.g., physical examination, urinalysis + Canine/Feline E.R.D.-HealthScreen® Urine Test, serum creatinine, blood pressure measurement)

2. Consider additional diagnostic procedures (e.g., thoracic and abdominal radiography, abdominal ultrasonography, serology for regionally prevalent infectious diseases, renal biopsy)

3. Options 2 through 5 from "Microalbuminuria Stable or Decreasing Recommendations"

4. Implement specific therapies reported to delay progression of renal disease such as prescription renal disease diet and ACE inhibitors

Step 2

Step 3

Check for Underlying Disease Conditions

Step 1Feline Microalbuminuria Rule OutsLower Urinary Tract Disease (FLUTD)

Canine Microalbuminuria Rule OutsUrinary Tract Inflammation (UTI)

COUNSELING OWNERS:

* Counsel owners on the importance of periodic health examinations, maintaining good oral health, heartworm testing and prevention, flea and tick prevention.

† Counsel owners on the importance of seeking medical attention for treatment of persistent vomiting or diarrhea.

Counsel owners on the importance of monitoring UPC ratios and on the recognition of early clinical signs associated with decreases in renal function.

Counsel owners on the recognition of early clinical signs associated with decreases in renal function (e.g., polyuria, polydipsia).

COUNSELING OWNERS:

PRODUCT SUPPORT? 1-800-464-3752, option 5 www.heska.com/erdscreen

COUNSELING OWNERS:

• Inflammatory diseases (e.g., dental disease, pyoderma, immune mediated diseases, IBD)

• Infectious diseases (e.g., heartworm, ehrlichiosis, Lyme)

• Metabolic diseases (e.g., diabetes mellitus, hyperadrenocorticsm, hypertension)

• Neoplasia

• Inflammatory diseases (e.g., dental disease, cholangiohepatitis, lower urinary tract disease (FLUTD), cholangiohepatitis, immune-medicated diseases, IBD)

• Infectious diseases (e.g., Fe:V. FIV. FIP, heartworm, ehrilichiosis)

• Metabolic diseases (e.g., diabetes mellitus, hypertension, hyperthyroidism)

• Neoplasia

Managing Patients with Positive E.R.D.-HealthScreen® Tests