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Semmelweis University Department of Traumatology Dr. Gál Tamás Management of open fractures. Septic and non-septic complications in Traumatology. Fractures of the tibia and fibula.

Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

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Page 1: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Semmelweis University

Department of Traumatology

Dr. Gál Tamás

Management of open fractures. Septic and

non-septic complications in Traumatology.

Fractures of the tibia and fibula.

Page 2: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Fractures of the Tibia Anatomical characteristics:

• Anteromedial surface: thin soft tissue

coverage open fractures (13%)

• Osteo-fascial muscle compartments

compartment syndroma (≤ 20%)

• Dynamic framework

• Tension between tibia and fibula

• 1/6th of the load on the fibula

• Elastic load absorption

Page 3: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

AO

Arbeitsgemeinschaft für

Osteosynthesefragen

Page 4: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys
Page 5: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Conservative treatment

• Stable, non-dislocated fractures

• General condition of the patient

Traction for 3 weeks…

Page 6: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Cast: 9-12 weeks

Page 7: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Operative treatment

• Intramedullary nailing

• Plate synthesis

• External Fixator

Page 8: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Indications of intramedullary nailing

for the treatment of tibia fractures

• Best choice for fractures between the 2/7-6/7th

(shaft fractures) if it can be technically carried out

• Reamed nailing: monotrauma, patient is allowed to

bear weight earlier, good for cases of mal-union or

non-union

• Unreamed nailing: polytrauma, shorter operation

time, Grade lll- types B-, C open fractures, narrow

intramedullary canal.

• Interlocking: gives rotational stability, static

interlocking recommended, dynamisation can be

later performed. Mandatory in unreamed nailing.

Page 9: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Reamed Intramedullary Nailing

Page 10: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Unreamed intramedullary nailing – UTN

(Unreamed Tibia Nail)

Page 11: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

IM nailing post operative care:

•if stability of the fracture is in question, then below knee cast

immobilization and touch down wt bearing are used until healing

•once partial fracture healing has taken place, consider a functional brace

or consider a below knee cast.

•active dorsiflexion and plantarflexion stresses the tibia and produces

displacements similar to wt bearing;

- static locking: most tibial fractures heal in the static locked mode;

- dynamization:

- removal of proximal or distal screws allows axial loading of tibia

- consider at 3 months in axially stable fractures with no callus

- axially unstable frx should remain in static mode and should receive bone

graft

Page 12: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Indications of plate synthesis

• Intraarticular fractures and fractures near

the joint (when ORIF is necessary)

• Non-union, malunion (with bone graft)

• When other methods of treatment are

contraindicated (e.g. compartment

syndrome)

Page 13: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys
Page 14: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Plate synthesis

Medial plate

Page 15: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Indications for External Fixation

• Severe soft tissue injury (Glll-BC) OPEN FRX

• In certain cases of polytraumatisation

• For intermittant limb shortening

• As a supplementation for minimal

synthesis epi-metaphyseal fractures

• Joint bridging

• Segment transfer, bone lengthening

Page 16: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

External fixation device

Page 17: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Ilizarov external fixation device

Page 18: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Compartment syndrome

increasing tissue pressure prevents

capillary blood flow and produces

ischemia in muscle and nerve tissue. The

process is progressive and leads to

necrosis with permanent loss of function!

Surgical Emergency…..

Otherwise amputation

Intracompartmental pressure > 30 mmHg

Page 19: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Causes • High-energy limb injuries (most

often calf area)

• Crushing injuries

• Burns

• Prolonged compression (comatose,

unprotected patient)

• Abnormal capillary permeability

caused by reperfusion after

prolonged ischemia. Tight

bandages, splints, or

casts….Volkmann ischemic

contracture

Page 20: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Compartment syndrome

• Edema

• Pallor

• Pain „like childbirth”

• Pain to Passive

movement

• Local hyp/Paraesthesia

• Paresis

• Pulselessness

FASCIOTOMY !!!

Page 21: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Open fractures – Gustillo and

Anderson classification

Page 22: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

55 y.o. male pedestrian was hit by an automobile.

Patient is HIV positiv. Grade I intraart. open tibia frx

Page 23: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Intraop. imaging

Page 24: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Postop. 12 weeks

Breakage of the 4

proximal screws

-8 weeks non-wt. bearing

- week 8-12 phys. ther.

(imitation of walking)

-12 th week – half wt bearing

-pain in the area of the op.

Page 25: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

-Another op

-7 extra screws

-callus formation

-postop 24 th week

jogging again

-fully recovered,

metal removal after

2 years

Page 26: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

INFECTION: the most serious complication for

both the patient and the doctor!

• Contamination

bacteria on site

* bakterial culture

* temperature

drain-cultures

germs ↑

immune status ↓

• Infection

signs of bacterial inf.

* rubor (hyperemia)

* tumor (edema)

* calor (warm)

* dolor (painful)

* functio laesa (loss of

function

* pus

Page 27: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Causes of infection

• Open wounds / fractures

• Iatrogenic infections

- sterility problem

- ultrasterile boxes

• Circulation problems, diabetes

• Immune status

- transplants / steroids

- oncologic illness

• Operative errors

- haematomas, tissue damage

Page 28: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Classification of infections 1.

• Acute

- early posttraumatic period (1-7 days)

• Subacute

- (1 week- 1 month)

• Chronic

- (after 1 month)

Page 29: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Classification of infections 2.

• superficial

- skin necrosis

- epifascial supp.

good prognosis!

• deep

- subfascial

- intraarticular

- tendovaginal

- body cavity

- peri-implant

bad prognosis!

Page 30: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Superficial infection

• Diagnostics

- inspection

- palpation

- Ultrasound

- lab results

• Therapy

- conservative/kryoth.

- operative (revision,

debridement, perhaps

drainage)

Page 31: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Deep infection

• Diagnostics

- inspection

- palpation

- Ultrasound

- aspiration

- labs

• Therapy

- immediate revision,

debridement

- suction drainage

(vaccum sealing)

- perhaps Septopal chain

or antibiotic cement

Subfascial, extra/intraarticular

haematoma, tissue damage

Page 32: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Diagnostic methods

• Laboratory

- WBC

- qualitative blood

- We (Erythrocyte Sedimentation Rate)

- CRP

- procalcitonin

- TNF

• Instrumental

diagnostics

- sonography (punction)

- x-ray (gas, fluid)

- CT/contrast

- MRI/contrast

- scintigraphy

- thermography (?)

Page 33: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

•obtain adequate cultures •Antibiotics should be considered only if the patient is systemically septic prior to wound exploration •Empirical antibiotic treatment is based upon the antibiotics sensitivities of likely infecting organisms

• history of previously positive cultures

• institutional frequency statistics

Page 34: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Antibiotic beads

Locally administered antibiotics may

have a supplementary role in the

management of musculoskeletal

infections.

poorly perfused areas, or “dead space”,

antibiotic-laden cement is frequently

used, both to fill the space and to

deliver high doses of local antibiotic

with low risk of systemic toxicity.

A common technique is the use of

antibiotic-laden PMMA beads.

Antibiotic-impregnated beads may

be purchased in some countries or

made by the surgeon more cheaply.

Page 35: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Circulation problem

Contraindication

Page 36: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

profylaxis: Radical debridement

Page 37: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Pathophysiology

Sequester

Area outside of

circulation

Page 38: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

ANTIBIOTICS parenteral / local

Page 39: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Time factor!

SEPTOPAL-prophylaxis

Open fracture prophylaxis

Magyar Traumatologia 28:280 (1985)

Page 40: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Local AB-therapy:

Protection of

osteosynthesis

under fracture

healing

Page 41: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Local AB-therapy

Page 42: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Local AB-therapy:

Fill area, ASP

preparation

Page 43: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Soft tissue-correction

Page 44: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Without debridement

local AB-treatment is

useless, contraindicated!

Disadvantage:

resistency

Page 45: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Intramedullary debridement

Page 46: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Intramedullary debridement

gravitational

drainage

intermittant

removal

Page 47: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Septic complication after femoral neck OS

Early

debridement,

2 session

TEP implant.

Page 48: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

GIRDLESTONE hip

42

éves chr.

alc.

Page 49: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

GIRDLESTONE-hip

Page 50: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Limb salvage

9 y.o. girl

Brain contusion

Rupture of stomach

Closed tibia frx

(car accident)

Page 51: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

„Second look”

Page 52: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys
Page 53: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Patient fell from a ladder, open distal

intraart frx of tibia and fibula

Page 54: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Angular plate synthesis

Page 55: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys
Page 56: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Osteomyelitis

Page 57: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Local

antibiotic

cement

Page 58: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys
Page 59: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Total Knee Replacement – 60 y.o.

male farmer

Page 60: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

3 months postop.

Antibiotic spacer

Page 61: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

7 months postop.

Revision TKR

•10 months postop

•Signs of loosening

again

Page 62: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

11 months postop.

AB spacer again

15 months postop.

Revision surgery again

Page 63: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Non-union

-34 year old

male was in a

fight, and

defended

himself with his

right foremarm

-ulna diaphysis

fracture

Page 64: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Postoperative x-ray

Page 65: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Postop. 3 months

Page 66: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Bone graft

Page 67: Management of open fractures. Septic and non-septic ...€¦ · • 1/6th of the load on the fibula • Elastic load absorption . AO Arbeitsgemeinschaft für ... - week 8-12 phys

Thank you for your attention