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8/3/2019 LSM3212_Lecture 1 Introduction
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Human Physiology: LSM 3212An Introduction:
The application of Human Physiology in exerciseand sports performance
1
A/Prof Lim Chin LeongBSc, MSc, MBA, PhD
Programme Director,Combat Protection and Performance
DMERI@[email protected]
Dept of Physiology,NUS NCAPSSC Singapore Institute of Clinical SciencesA*STAR
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Human Physiology
The study of humanbody functions
Human Anatomy
The study of humanstructure and morphology
2
FunctionsSystemsOrgansCellsProtein
formationRNA
formationDNA
formation
The Organization of Human Physiology
StrengthMuscularNervousSkeletalMetabolic
MusclesNerves
GlycolysisM. typeM. FibersM. Fibrils
MyosinActin
ExpressionRegulatione.g., ACTN3,IFG-1
ExpressionRegulatione.g., ACTN3
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Physiological Systems of the Human
Cardiovascular
Cardiopulmonary
Muscularskeletal
Digestive
Cognition
3
Endocrine
NervesUrinary
Immune
Metabolism
Thermoregulation
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Physiological Systems of the Human
Cardiovascular
Cardiopulmonary
MuscularSkeletal
Metabolism
Digestive
Cognition
4
Endocrine
NervesUrinary
Immune
Thermoregulation
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Physiological Systems of the Human
Cardiovascular
Cardiopulmonary
MuscularSkeletal
Metabolism
Digestive
Cognition
5
Endocrine
Nerves
Urinary
Immune
Thermoregulation
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Extremes of Physiological Systems in Sport
Cardiovascular
Cardiopulmonary
MuscularSkeletal Metabolism
Digestive
6
Endocrine
Nerves Urinary
Immune
Thermoregulation
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HomeostasisThe body will function to preserve its physiological
equilibrium in order to survive the demands of theenvironment.
7
Immediate adaptation e.g., heart rate, body temperature andenergy production.
Chronic adaptation
Longer term adaptation e.g., changes in fitness and performancelevels and body composition.
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Healthy and at rest
Physical exertionIllness /
The Dimensions of Physiological State and Homeostasis
Non-survival /Chronic injury
Shift in baseline physiology to
survive at a new state ofexistence. Key issues: Acute adaptation Chronic adaptation
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Extreme PerformanceOver exertion
Challengeto regulate
Limits of regulation
Dysregulation
ar a ons n a ap a on Limits of adaptations Mechanisms of adaptation Interpretation of physiology
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Exercise is a Form of Stress
9
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STRESS :
Stressor: The source of the stress
Demands an adaptation from the body
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ustress: e goo stress
Distress: The bad stress
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THE STRESS CONTINUUM
EustressImproved fitness
DistressBurnout
EXERCISE
11
Cope better with daily
tasks
Improved self-image &confidence
Stronger immune system
Injury
Substance abuse
Distorted self-image
e.g muscle dysmorphia,
aneroxia nervosa.
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STRESS ADAPTATION SYNDROME
NCE
PEAK
12
PERFORM
ALARM
TIME
ADAPTATION FATIGUE
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Physical Activity / Exercise
Health
Driven
Performance
Driven
Purpose / Motivation
Stress
Commitment
Intensity / Pain
Outcome
Time span
Sacrifice
Health risk
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Health Benefits of Exercise
14
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Health Benefits of Exercise
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Are fitness and health the same??
HealthFitness
Physical Exercise
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Fitness and Health Relationship
HealthFitness
Health BenefitsIndividual risks
Gill and Cooper Sports Med 2008
Physical Exercise
Aerobic capacityBody compositionMuscular strengthMuscular enduranceMuscular speed
FlexibilityAgilityCoordinationEndurance
ObesityInsulin resistanceGlucose toleranceLipid profileCV health
Blood pressureBone densitySoft tissueMental health
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The Continuum of Human Performance
ical
rmance Negative return
Neutral return
Positive return
Untrained Optimal Maximal Over
Phy
Perf
Training Volume
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Intense Exercise: A Double Edged Sword
Execution of Training
Desired outcome Disastrous outcomeUndesired outcome
19Training Load
StressTolerance
Limit of Tolerance+ve Adaptation
-ve Adaptation
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20
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INDIVIDUAL DIFFERENCES IN RESPONSE
TO TRAINING
Variations in improvement inVO2 max following 20 weeks
of endurance training byfamily.
Average was 18% but the
21
range was .
The range was influenced bygenetics but was influencedvery little by age, sex andrace.
Adapted from C. Bouchard et al., 1999, Familiaraggregation of VO2 max response to exercisetraining. Results from HERITAGE Family Study,Journal of Applied Physiology 87: 10031008.
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Cardiopulmonary and Vascular Systems
Heart
Lungs
Blood vessels
Arteries: transport oxygenated blood
: transport blood from the
heart to the organs/ muscles
Veins: transport deoxygenated
blood
22
: transport blood from organsto the heart
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CAPACITY OF THE LUNG
24
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Primary Roles of the Pulmonary System
during Exercise
Inhalation of oxygen.
Oxygen supply
Diffusion of O2 into the pulmonary vein capillaries.
25
CO2 removal
Diffusion of CO2 from Pulmonary artery capillaries into thealveoli.
Exhalation of carbon dioxide
Acid - Base balance.
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CARDIOVASCULAR SYSTEM
26
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FUNCTIONS DURING EXERCISE
Transportation of oxygen to exercisingmuscles.
Removal of carbon dioxide and lactatefrom exercising muscles.
27
exercising muscle.
Removal of heat from exercisingmuscle.
Transportation of heat to skin surface.
Maintenance of blood flow.
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Autonomic Nervous System
Part of peripheral nervoussystem that coordinates thefunctions of major organs
Activated mainly by the spinalcord, brain stem andhypothalamus
Major organs under the control ofthe ANS:
Heart
Bronchus
28
Comprises of sympathetic andparasympathetic systems
SNS: Fight or flight system
PSNS: Promotes functions ofthe resting state.
Stomach
Kidney
Blood vessels
Intestines
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Key Roles of ANS During Exercise
Heart rate
Stroke volume
Cardiac output
VO2
Blood pressure
29
Blood distribution
Thermoregulation
Sweating
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Unnatural Alteration of Physiology
for Sports Performance
30
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Breakdown of the ancient Olympic games some2000 years ago was due to political interferenceand the use of drugs.
The first reported death from doping occurred in1886 when a cyclist, Arthur Linton, took caffeine.
History of Doping Cases in Sports
31
The first near death in the modern Olympicsoccurred in 1904 when Thomas Hicks, collapsedafter taking a mixture of brandy and strychnine in amarathon.
Danish cyclist Knut Jensen collapsed and died inthe heat of the Rome Olympics in 1960 after takingronicol tablets and amphetamines in the belief thatthey would increase blood flow through his
muscles.
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In 1986 European Champion shot-putter Heidi Krieger was a long termuser of male hormone injections
under state run doping programmesin East Germany.
I was no longer Heidi Krieger. I
History of Doping Cases in Sports
32
n t now anymore w o was
wasnt able to identify with my bodyanymore, and that led me toundergo a sex change
Today Krieger is a gruff-voiced 40-year old man called Andreas.
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Ben Johnson (Canada)tested positive for anabolicsteroids at Seoul in 1988.
1984: LA Olympics, Bronze100 m
1984: LA Olympics, Bronze,
History of Doping Cases in Sports
33
1987: World Championship,Disqualified, 100m
1988: Seoul Olympics,
Disqualified, 100m
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Floyd Landis, winner of the2006 Tour de France winnerFloyd Landis.
Overcame a normallyinsurmountable 8 min deficitin the final days of the 3-week race.
History of Doping Cases in Sports
34
Tested positive for syntheticsteroids in 17 of his urinesample after his winningrace.
Spent about US$2 Mil in hisdefence.
Stripped of his title in 2007