1- Lesional tissue specimens 1Size : 2.3 x 2.3 x 1.3 cm Location : subcutis

1D- Specimens for diagnosis :Weights : D1 : 138.6 mg, D2 : 146.7 mg1R- Specimens for research : Nb : 5Weights : R1 : 92.8 mg, R2 : 90 mg, R3 : 112.6 mg, R4 : 185.6 mg, R5 : 178.7 mgPercent of Percent of tumortumor cellscells : 10 %: 10 %

Pathologist : C.BUTORI12/04/2006 Time for frozen procedure : 20 mn

Diagnosis and staging : cutaneous and pleural metastasis from a mammary ductal adenocarcinomaDiagnosis of frozen specimens :Lesion n°1 : cutaneous metastasisLesion n°2 : pleural metastasis

Patient : N°LH 06-2268 N°LB 06-601 ID : MI MAConsent : YES

2- Lesional tissue specimens 2Location : right pleuraHistology : mammary ductal adenocarcinoma, metastasis2D- Specimens for diagnosis :Weights : D1 : 89.4 mg2R- Specimens for research : Nb : 5Weights : R1 : 98.9 mg, R2 : 30.4 mg, R3 : 92.9 mg, R4 : 60.7 mg, R5 : 29.7 mgPercent Percent ofof tumortumor cellscells : 10 %: 10 %

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)

Destock :

CPS

Age : 56

Sex : F

Infection : NOFor diagnosis bank : NO

3- Morphological controls (mirrors) :

Lesion 1 Lesion 2

1- Lesional tissue specimensSize : 4 x 3 x 3 cm Location : ventral segment, right upper lobe

1D- Specimens for diagnosis :Weights : D1 : 81 mg, D2 : 68.2 mg1R- Specimens for research : Nb : 5Weights : R1 : 100 mg, R2 : 77.8 mg, R3 : 59.8 mg, R4 : 91 mg, R5 : 133.1 mg

Percent of tumor cells Percent of tumor cells : 20 %: 20 %

Pathologist : V. HOFMAN12/05/2006 Time for frozen procedure : 25 mn

Diagnosis and staging : well differentiated squamous cellcarcinoma with keratinization pT2N0MxDiagnosis of frozen specimens : well differentiated squamous cell carcinoma with keratinization

Patient : N°LH 06-2277 N°LB 06-604 ID : AF LAConsent : YES

2- Perilesional tissue specimensLocation : parenchymaHistology : mild emphysema

2D- Specimens for diagnosis :Weights : D1 : 87.1 mg, D2 : 86 mg2R- Specimens for research : Nb : 5Weights : R1: 45.8 mg, R2 : 68.3 mg, R3 : 90.6 mg, R4 : 155.6 mg, R5 : 75.6 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)Lesion :- C°: 0.164 µg/µl ; Tot qty : 27.1 µg- DO 260/280 : 1.93 ; PCR GAPDH : OK

Destock : 2008-8BioBank

CPS

Age : 60

Sex : F

3- Morphological controls (mirrors) :

Lesion Perilesion

Infection : NOFor diagnosis bank : NO

1- Lesional tissue specimensSize : 3 x 2.5 x 2.5 cmLocation : left upper lobe

1D- Specimens for diagnosis :Weights : D1 : 106,3 mg, D2 : 226,7 mg1R- Specimens for research : Nb : 5Weights : R1 : 177,7 mg, R2 : 138,3 mg, R3 : 135,8 mg, R4 : 165,1 mg, R5 : 140,0 mg

Percent of Percent of tumortumor cellscells : 30 %: 30 %

Pathologist : V. HOFMAN12/05/2006 Time for frozen procedure : 30 mn

Diagnosis and staging : squamous cell carcinoma basaloidvariant pT2N2Mx (grade 3)Diagnosis of frozen specimens : squamous cell carcinomabasaloid variant

Patient : N°LH 06-2284 N°LB 06-608 ID : SA JEConsent : YES

2- Perilesional tissue specimensLocation : lingulaHistology : moderate emphysema

2D- Specimens for diagnosis :Weights : D1 : 106,3 mg, D2 : 226,7 mg2R- Specimens for research : Nb : 5Weights : R1 : 177,7 mg, R2 : 138,3 mg, R3 : 135,8 mg, R4 : 165,1 mg, R5: 140,0 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

Age : 69

Sex : M

4- Controls of qualityRNA (quality and quantity available)

Lesion

Perilesion

DNA (quality and quantity available)Lesion :- C°: 0.1712 µg/µl ; Tot qty : 33.5 µg- DO 260/280 : 1.96 ; PCR GAPDH : OKPerilesion : - C°: 0.0226 µg/µl ; Tot qty : 4.3 µg- DO 260/280 : 1.93 ; PCR GAPDH : OK

Destock : BIOBANK

CPS

rRNA 28S/18S: 1.7C°: 0.863 µg/µlTot qty : 40.7 µg

rRNA 28S/18S: 1.2C°: 0.251 µg/µlTot qty : 11.6 µg

3- Morphological controls (mirrors) :

Lesion Perilesion

Infection : NOFor diagnosis bank : NO

1- Lesional tissue specimensSize : 5 x 3 cmLocation : proximal right lower lobe

1D- Specimens for diagnosis :Weights : D1 : 131.7 mg, D2 : 173.7 mg1R- Specimens for research : Nb : 5Weights : R1 : 272.9 mg, R2 : 257 mg, R3 : 175.9 mg, R4 : 223 mg, R5 : 176.4 mg

Percent of Percent of tumortumor cellscells : 40 %: 40 %

Pathologist : C. BUTORI12/06/2006 Time for frozen procedure : 15 mn

Diagnosis and staging : lung metastasis of colic adeno-carcinomaDiagnosis of frozen specimens : tubulo-papillar and cribriform

Patient : N°LH 06-2287 N°LB 06-609 ID : MO FRConsent : YES

2- Perilesional tissue specimensLocation : parenchymaHistology : normal

2D- Specimens for diagnosis :Weights : D1 : 285.1 mg, D2 : 145 mg2R- Specimens for research : Nb : 5Weights : R1 : 269.8 mg, R2 : 261.4 mg, R3 : 287.4 mg, R4 : 256.6 mg, R5 : 245.8 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)Lesion :

- C°: 0.219µg/µl; Tot qty : 41.83 µg- DO 260/280 : 1.94 ; PCR GAPDH : OK

Destock : Biobank 2008-6C

CPS

Age : 63

Sex : F

3- Morphological controls (mirrors) :

Lesion Perilesion

Infection : NOFor diagnosis bank : NO

1- Lesional tissue specimensSize : 1.8 x 1.5 cmLocation : peripheral apical left upper lobe

1D- Specimens for diagnosis :Weights : D1 : 113.4 mg, D2 : 144.4 mg1R- Specimens for research : Nb : 5Weights : R1 : 157.8 mg, R2 : 130.4 mg, R3 : 117.9 mg, R4 : 175.4 mg, R5 : 71 mg

Percent of Percent of tumortumor cellscells : 30 %: 30 %

Pathologist : C. BUTORI12/06/2006 Time for frozen procedure : 20 mn

Diagnosis and staging : adenocarcinoma mixed sub-type pT1N0Mx (grade 3)Diagnosis of frozen specimens : adenocarcinoma mixed sub-type with cribriform and massive architecture

Patient : N°LH 06-2290 N°LB 06-610 ID : HE GIConsent : YES

2- Perilesional tissue specimensLocation : lingulaHistology : mild emphysema and alveolitis

2D- Specimens for diagnosis :Weights : D1 : 97.4 mg, D2 : 69.8 mg2R- Specimens for research : Nb : 5Weights : R1 : 128.9 mg, R2 : 135.4 mg, R3 : 150.4 mg, R4 : 114.9 mg, R5 : 106.9 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)

Destock :

CPS

Age : 60

Sex : M

3- Morphological controls (mirrors) :

Lesion Perilesion

Infection : NOFor diagnosis bank : YES

1- Lesional tissue specimensSize : 12 x 5.5 cmLocation : anterior mediastinum

1D- Specimens for diagnosis :Weights : D1 : 229.2 mg, D2 : 260 mg1R- Specimens for research : Nb : 5Weights : R1 : 272.4 mg, R2 : 136.2 mg, R3 : 212.3 mg, R4 : 270.4 mg, R5 : 209.5 mg

Percent of Percent of tumortumor cellscells : 20 %: 20 %

Pathologist : S. LASSALLE12/07/2006 Time for frozen procedure : 20 mn

Diagnosis and staging : mature teratoma

Diagnosis of frozen specimens : mature teratoma (squamous epithelium and appendages predominant)

Patient : N°LH 06-2297 N°LB 06-612 ID : RO ANConsent : YES

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)

Destock :

CPS

Age : 25

Sex : F

2- Perilesional tissue specimens

None

Infection : NOFor diagnosis bank : NO

Not available

3- Morphological controls (mirrors) :

Lesion Perilesion

1- Lesional tissue specimensSize : 3.2 x 2 cmLocation : apical right upper lobe

1D- Specimens for diagnosis :Weights : D1 : 117.3 mg, D2 : 183 mg1R- Specimens for research : Nb : 5Weights : R1 : 143 mg, R2 : 84.9 mg, R3 : 147.6 mg, R4 : 238.9 mg, R5 : 132 mg

Percent of Percent of tumortumor cellscells : 40 %: 40 %

Pathologist : C. BUTORI12/12/2006 Time for frozen procedure : 15 mn

Diagnosis and staging : squamous cell carcinoma pT2N2Mx (grade 1)Diagnosis of frozen specimens : well differentiated squamous cell carcinoma with keratinisation

Patient : N°LH 06-2337 N°LB 06-622 ID : IE REConsent : YES

2- Perilesional tissue specimensLocation : ventral segmentHistology : mild alveolitis

2D- Specimens for diagnosis :Weights : D1 : 89 mg, D2 : 136.5 mg2R- Specimens for research : Nb : 5Weights : R1 : 148.6 mg, R2 : 125.9 mg, R3 : 126 mg, R4 : 200 mg, R5 : 145.9 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)

Destock :

CPS

Age : 53

Sex : F

3- Morphological controls (mirrors) :

Lesion Perilesion

Infection : NOFor diagnosis bank : NO

1- Lesional tissue specimensSize : 2.2 x 2 cmLocation : left upper lobe

1D- Specimens for diagnosis :Weights : D1 : 125.3 mg, D2 : 104.2 mg1R- Specimens for research : Nb : 5Weights : R1 : 115.7 mg, R2 : 71.3 mg, R3 : 149 mg, R4 : 120.7 mg, R5 : 102.2 mg

Percent of Percent of tumortumor cellscells : 35 %: 35 %

Pathologist : C. BUTORI12/13/2006 Time for frozen procedure : 20 mn

Diagnosis and staging : well differentiated adenocarcinomamixed subtype with very focal bronchiolo-alveolar compon ent pT1N2MxDiagnosis of frozen specimens : well differentiated adeno-carcinoma, tubulo-papillar

Patient : N°LH 06-2347 N°LB 06-623 ID : KO AGConsent : YES

2- Perilesional tissue specimensLocation : lower lingulaHistology : mild bronchiolitis and alveolitis

2D- Specimens for diagnosis :Weights : D1 : 142.3 mg, D2 : 163.6 mg2R- Specimens for research : Nb : 5Weights : R1: 230.6 mg, R2 : 173.4 mg, R3 : 293.1 mg, R4 : 191.8 mg, R5 : 140.8 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)

Destock : 2006-11

CPS

Age : 64

Sex : F

Infection : NOFor diagnosis bank : YES

3- Morphological controls (mirrors) :

Lesion Perilesion

1- Lesional tissue specimensSize : 1.5 cmLocation : left upper lobe

1D- Specimens for diagnosis :Weights : D1 : 77,6 mg1R- Specimens for research : Nb : 3Weights : R1 : 77,8 mg, R2 : 82,1 mg, R3 : 51,1 mgPercent of tumor cells Percent of tumor cells : 50 %: 50 %

Pathologist : C. BUTORI12/19/2006 Time for frozen procedure : 15 mn

Diagnosis and staging : poorly differentiated adenocarcinomamixed subtype pT1N0MxDiagnosis of frozen specimens : trabecular and acinar poorlydifferentiated adenocarcinoma

Patient : N°LH 06-2380 N°LB 06-633 ID : PI GIConsent : YES

2- Perilesional tissue specimensLocation : lingulaHistology : mild emphysema

2D- Specimens for diagnosis :Weights : D1 : 116,9 mg, D2 : 86,2 mg2R- Specimens for research : Nb : 5Weights : R1 : 91,8 mg, R2 : 113,0 mg, R3 : 154,2 mg, R4 : 209,9 mg, R5 : 183,0 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)Lesion :- C°: 0.296 µg/µl ; Tot qty : 53 µg- DO 260/280 : 1.97 ; PCR GAPDH : OK

Destock : BioBank / 2008-8/ 2008-3BioBank / 2006-11

CPS

Age : 55

Sex : F

Infection : NOFor diagnosis bank : YES

3- Morphological controls (mirrors) :

Lesion Perilesion

1- Lesional tissue specimensSize : 6 x 5 x 5 cmLocation : dorsal right upper lobe

1D- Specimens for diagnosis :Weights : D1 : 167,2 mg, D2 : 181,0 mg1R- Specimens for research : Nb : 5Weights : R1 : 146,8 mg, R2 : 234,2 mg, R3 : 211,5 mg, R4 : 146,9 mg, R5 : 177,4 mg

Percent of tumor cells Percent of tumor cells : 50 %: 50 %

Pathologist : V. HOFMAN12/21/2006 Time for frozen procedure : 25 mn

Diagnosis and staging : solid mucinous adenocarcinoma(grade 3) pT2N0MxDiagnosis of frozen specimens : solid mucinous adeno-carcinoma

Patient : N°LH 06-2403 N°LB 06-637 ID : DE CLConsent : YES

2- Perilesional tissue specimensLocation : right upper lobeHistology : emphysema

2D- Specimens for diagnosis :Weights : D1 : 102,1 mg, D2 : 81,0 mg2R- Specimens for research : Nb : 5Weights : R1 : 106,4 mg, R2 : 179,9 mg, R3 : 136,5 mg, R4 : 109,3 mg, R5 : 131,5 mg

BIOBANK LPCE-NICECHESTCHEST

LPCE / CHU Unit LPCE / CHU Unit

4- Controls of qualityRNA (quality and quantity available)

DNA (quality and quantity available)Lesion :- C°: 0.170 µg/µl ; Tot qty : 28.3 µg- DO 260/280 : 1.95 ; PCR GAPDH : OK

Destock : 2008-3 / 2008-8 BioBank

CPS

Age : 60

Sex : M

Infection : NOFor diagnosis bank : YES

3- Morphological controls (mirrors) :

Lesion Perilesion