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PharmacoEconomics & Outcomes News 462 - 25 Sep 2004 Lower IOP correlates with stable disease, lower treatment costs The early management of disease by a glaucoma specialist "could reduce the economic burden of treatment and could improve the probability of stabilizing a patient", say researchers from the US and Canada. Using data obtained from patient charts (n = 265), the researchers retrospectively determined the association between intraocular pressure (IOP) control levels and disease stability, and the cost of treating primary open- angle glaucoma; patients were classified as having mild, moderate or severe disease based on visual field mean deviation scores. * The findings suggest that there is an association between lower IOP control levels and a higher probability of stable disease, "and a decrease in the cost of treatment", note the researchers. In patients with mild disease, the cost of treatment did not change significantly with a change in mean IOP; however, "there was a trend towards a higher correlation between mean IOP and the cost of treatment in patients with severe disease", they add. * Funding for the study was provided by Alcon Research Ltd, US. Vicente C, et al. Association between mean intraocular pressure, disease stability and cost of treating glaucoma in Canada. Current Medical Research and Opinion 20: 1245-1251, No. 8, Aug 2004 800989176 1 PharmacoEconomics & Outcomes News 25 Sep 2004 No. 462 1173-5503/10/0462-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Lower IOP correlates with stable disease, lower treatment costs

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PharmacoEconomics & Outcomes News 462 - 25 Sep 2004

Lower IOP correlates with stabledisease, lower treatment costs

The early management of disease by a glaucomaspecialist "could reduce the economic burden oftreatment and could improve the probability ofstabilizing a patient", say researchers from the US andCanada.

Using data obtained from patient charts (n = 265), theresearchers retrospectively determined the associationbetween intraocular pressure (IOP) control levels anddisease stability, and the cost of treating primary open-angle glaucoma; patients were classified as having mild,moderate or severe disease based on visual field meandeviation scores.* The findings suggest that there is anassociation between lower IOP control levels and ahigher probability of stable disease, "and a decrease inthe cost of treatment", note the researchers. In patientswith mild disease, the cost of treatment did not changesignificantly with a change in mean IOP; however, "therewas a trend towards a higher correlation between meanIOP and the cost of treatment in patients with severedisease", they add.* Funding for the study was provided by Alcon Research Ltd, US.

Vicente C, et al. Association between mean intraocular pressure, disease stabilityand cost of treating glaucoma in Canada. Current Medical Research and Opinion20: 1245-1251, No. 8, Aug 2004 800989176

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PharmacoEconomics & Outcomes News 25 Sep 2004 No. 4621173-5503/10/0462-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved