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© Copyright National University of Singapore. All Rights Reserved.
LOWER GIT ANATOMY
Assoc Prof Dinesh Kumar Srinivasan
MBBS, MS, PhD (NUS), Fellow (USA)
Co-Chair, Integrated Lead Educators
Department of Anatomy
Yong Loo Lin School of Medicine, NUS
2nd Nov 2017 @ 8.30 - MD1 LT37
© Copyright National University of Singapore. All Rights Reserved.
• Sympathetic nerve fibres
(preganglionic) pass through
the greater splanchnic
nerves and terminate in the
celiac ganglion
• Postganglionic sympathetic
nerves supply the stomach
• Stomach is supplied by the
sensory (pain) fibres which
accompany the sympathetic
nerve fibres and reach the
T5-T9 spinal sensory
ganglia
• Visceral referred pain from
gastric ulcer is referred to
the epigastric region
Nerve Supply of the Stomach
Erratum
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OBJECTIVES
• To describe the location of peritoneal spaces, and understand their
clinical significance
• To describe the location, structural features, vascular supply and
innervation of the pancreas, small and large intestines
• To understand the relations of each of these organs with neighbouring
structures
• To appreciate the anatomical basis of these organs for clinical
examination, surgical operation and patient management
• To name the main branches/tributaries of the abdominal aorta and
inferior vena cava, and know their location and course
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• The peritoneal cavity is a POTENTIAL space within the layer of
peritoneum.
Peritoneal Cavity
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Lesser Sac (Omental Bursa)
• Lies posterior to the
stomach and the lesser
omentum
• Superiorly bounded by the
diaphragm
• Inferiorly bounded by the
layers of greater omentum
• Communicates with the
greater sac through the
omental foramen
• Its left margin is formed by
the spleen
Stomach
Greater Omentum
Peritoneal Cavity
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View from below
leftright
View from above
left right
Peritoneal Reflections
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Transverse mesocolon
Greater sac
Peritoneal cavity in sagittal section showing the arrangement of the lesser
sac (light blue) and the greater sac (light pink).
Greater Sac: main part of
the peritoneal cavity
– Transverse mesocolon
divides the greater sac
into:
• Supracolic
compartment
(stomach, liver and
spleen)
• Infracolic
compartment (small
intestine and colon)
Peritoneal Cavity
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Peritoneal Compartments
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Posterior abdominal wall (anterior view)
Supracoliccompartment
InfracolicCompartment(Right & Left)
Rt. paracolicgutter Lt. paracolic
gutter
Mesentery of transverse colon
Mesentery of small intestine
Peritoneal Compartments
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Paracolic gutters lie on the
lateral sides of the
ascending and descending
colons
Right paracolic gutter
communicates with right
subhepatic space
Left paracolic gutter is
separated from the
diaphragm by the
phrenicocolic ligament
Peritoneal Compartments
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Pancreas
Pancreas
• Retroperitoneal
• Lies between the duodenum
(on the right) and spleen (on
the left)
• Divided into:
• Head, neck, body, tail and
uncinated process
• The root of the transverse
mesocolon lies along its
anterior margin
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Tail
Components
• Head, neck, body, tail
• Uncinate process
Ducts
• Main pancreatic duct
opens into the ampulla
of vater. Accessory
pancreatic duct opens
into the duodenum.
Functions
• The pancreas produces
an exocrine secretion
that enters the
duodenum and
endocrine secretions
that enter the blood
Body
Body
Head
Main duct
Accessory duct
Uncinate process
Neck
Pancreas
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Relations
Head of pancreas:
attached to the descending part
of the duodenum; common bile
duct lies posteriorly
Neck of pancreas:
to superior mesenteric vessels
posteriorly
Body of pancreas:
forms the floor of the omental
bursa
stomach anteriorly
left kidney posteriorly
Tail of pancreas:
related to the hilum of the
spleen
Stomach
Spleen
Pancreas
Duodenum
(L) Kidney
CommonBile duct
Pancreas
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Splenic artery
Anterior superior
Pancreatico
duodenal artery
Anterior inferior
Pancreatico
duodenal artery
Superior Mesenteric artery
Supplied by the:
Head:
Branches of the
gastroduodenal and
superior mesenteric
arteries via
• Superior pancreatico
duodenal arteries
• Inferior pancreatico
duodenal arteries
Neck, Body, Tail:
Branches of splenic artery
Blood Supply of the Pancreas
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Venous Drainage
Splenic vein and Portal vein
Nerve Supply
Sympathetics
Decrease pancreatic
secretion.
Parasympathetics
Increase pancreatic
secretion.
Blood Supply & Innervation of Pancreas
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CD
Portal-Systemic Anastomoses
• Important sites of PSA
are lower oesophagus
(A), rectum (B), umbilicus
(C), and posterior
abdominal wall (D)
• Haemorrhage is common
from the first two sites –
A, B
• Liver or portal obstruction
causes these veins to
dilate widely, possibly
leading to severe venous
haemorrhage from
oesophagus or rectum
Alcoholic liver cirrhosis caused by
destruction of hepatocytes leads to portal
hypertension. Cirrhosis may be treated
by anastomosing the portal and systemic
venous systems
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Clinical Anatomy
1. Pancreatitis - inflammation of pancreas which is
associated with alcoholism
2. Cancer of head of pancreas can obstruct common bile
duct giving rise to obstructive jaundice
Duodenum
Common bile duct
lies behind head of
pancreas. Hence a
cancerous mass in
the head of
pancreas can
compress the
common bile duct.
Head of pancreas
Pancreas
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Small intestine
• Extends from the pylorus of the
stomach to the ileocecal
junction
• Major part of digestion and
absorption takes place in the
small intestine
• Divided into:
• Duodenum
• Jejunum
• Ileum
Small Intestine
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• 10 inches long; divided into 4 parts
• FIRST part of duodenum = DUODENAL CAP
• Most duodenal ulcers occur here
• SECOND part of duodenum contains entrance for common bile duct – MAJOR DUODENAL
PAPILLA
• Most of the duodenum is RETROPERITONEAL.
1
2
34
Gastroduodenaljunction Duodenojejunal
junction
Duodenum
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1
2
3
4
Duodenum:
1. 5 cm long, L1 level
2. 7-10 cm, rt of L1-L3
3. 6-8 cm, crosses L3
4. 5 cm, to L2
Duodenum
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Supplied by the branches of celiac
trunk and superior mesenteric
artery
Superior pancreatico duodenal
artery (indirectly from celiac):
supplies the part above the entry of
bile duct
Inferior pancreatico duodenal artery
(a direct branch of SMA): supplies
the part distal to the entry of bile duct
Both superior and inferior pancreatico
duodenal arteries anastomose
Duodenal veins drain into the portal
vein
Innervated by the
sympathetic nerves from the celiac
and superior mesenteric plexus and
parasympatheric (vagus)
Neurovasculature of the Duodenum
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Duodenal ulcer:
• Occurs commonly in superior part of the duodenum either anteriorly
or posteriorly
• Anterior duodenal ulcer erodes peritoneum causing peritonitis
• Posterior duodenal ulcer erodes either gastroduodenal artery or
posterior superior pancreaticoduodenal artery causing hemorrhage
(fatal in some cases)
Duodenum
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Jejunum and Ileum
Anterior view
• Jejunum and ileum
forms the rest of the
small intestine
• Duodeno jejunal
junction to ileocaecal
junction
• Length 20 feet
approximately. Upper
2/5 jejunum rest ileum.
• Entirely intraperitoneal
• Jejunal loops - LUQ.
• Ileal loops – RLQ.
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• Fan shaped mesentry
with long free edge
and a short root (red
line)
• Mucosa – circular
folds plicae circulares
• Peyer’s patches
(lymphoid tissue)
frequent in terminal
ileum.
Root of mesentery
Mucosa
Jejunum and Ileum Morphology
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• Proximal two-fifths
• Wide-bored & thick-walled. Closely
arranged plicae inside.
• Less prominent ARTERIAL
ARCADES
• Longer VASA RECTA
• Distal three-fifths
• Smaller in diameter & thinner
walls
• Prominent ARTERIAL
ARCADES
• Shorter VASA RECTA
Vasa recta
Arterial arcades
Jejunum vs Ileum
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Portal vein
SMV
Splenic vein
IMV
• Arterial supply from the
superior mesenteric artery
(SMA)
• Superior mesenteric vein
(SMV) drains the venous
blood from the jejunum and
ileum into portal vein
• SMV joins with splenic vein
to form the portal vein
Jejunum and Ileum
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• The small intestine is supplied by
autonomic (sympathetic and
parasympathetic) and sensory
fibers in the celiac and superior
mesenteric plexuses.
• Sympathetic fibres (greater
splanchnic):
• reduce bowel motility
• reduce intestinal secretions
• cause vasoconstriction
• Parasympathetic nerve fibres
(vagus):
• increase bowel motility
• stimulate intestinal secretions
• cause vasodilation
• The sensory fibers are sensitive
to distension and nociceptive pain
Nerve Supply to Small Intestine
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• Lymphatic vessels from
the walls of jejunum and
ileum drain into
mesenteric lymph
nodes (found between
the layers of
mesentery).
• Efferent lymphatic
vessels from the
mesenteric nodes drain
to the superior
mesenteric nodes
(found around the origin
of SMA)
Lymphatics Vessels of Jejunum and Ileum
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• Extends from ileum to anus
• Caecum, appendix,
ascending, transverse,
descending, and sigmoid
colon, rectum and anal
canal.
• Taenia coli, Haustra,
appendices epiploicae
(fatty tags) are main
features
• Iliocaecal valve – folds of
mucosa- not effective.
• Physiological sphincter at
terminal ileum
• Appendix (3- 5”) with its
short mesentery
(mesoappendix).
The Large Intestine
Visceral pain from
appendix is referred to
T10 dermatome
(umbilicus)
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• Lies below the
junction of the ileum
and large intestine in
the right iliac fossa
• has 3 bands of teniae
coli
• has no mesentery
Cecum
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• Lies in the RLQ
• Forms right colic flexure
(arrow)
• Supplied by right colic
branches of SMA
• Innervated by vagus and
sympathetic
Ascending Colon
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• Occupies the umbilical region
• Extends from right to left colic flexures (arrows)
• Suspended by the transverse mesocolon
• Supplied by middle colic artery (from SMA) and left colic artery (from IMA)
• Innervation: • proximal 2/3rd: by
parasympathetic vagusand sympathetic;
• distal 1/3rd: by parasympathetic pelvic splanchnic and sympathetic
Mesocolon
Transverse Colon
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• Retroperitoneal
• Begins at splenic
flexure to end at the
pelvic brim
• Supplied by left colic
branches of inferior
mesenteric artery
(IMA)
• Parasympathetic
innervation by pelvic
splanchnic nerve
Descending Colon
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• Links the descending colon with rectum
• Suspended by a mesentery (sigmoid mesocolon)
• Supplied by the sigmoid branches of IMA
• Innervated by the lumbar part of the sympathetic trunk and pelvic parasympathetic (inferior hypogastric plexus)
Sigmoid Colon
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3 UNPAIRED arteries arising from the anterior of the AORTA
COELIAC TRUNK = FOREGUT + liver, pancreas and spleen
SUPERIOR MESENTERIC ARTERY (SMA) = MIDGUT
INFERIOR MESENTERIC ARTERY (IMA) = HINDGUT
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Branches of Superior Mesenteric Artery
Middle colic artery
ileocolic artery
Right colic artery
Jejunal arteries
Ileal arteries
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Branches of Inferior Mesenteric Artery
• The junction of the mid- and
hindgut is near the left
(splenic) flexure of the colon.
• There is a change from
superior to inferior
mesenteric artery supply at
this level, but with
anastomoses between them.
Left colic artery
Sigmoid arteries
Superior rectal artery
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• The lymphatic drainage of the
bowel follows the arterial
supply, not the venous
drainage.
• The lymph nodes are grouped
around the abdominal aorta
• All lymph drains into the
cisterna chyli.
• Cisterna chyli is an
elongated lymphatic sac
located in front of the L1 & L2
bodies
• The thoracic duct
commences from the cisterna
chyli
LymphaticsCoeliac nodes
Superior mesenteric nodes
inferior mesenteric nodes
Cisterna chyli
Thoracic duct
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Innervation of the gut
• Abdominal viscera supplied by AUTONOMIC nervous system.
• Sensory fibres most important
• Sympathetic sensory (mediate PAIN):
– THORACIC SPLANCHNIC (T5-T12)
– LUMBAR SPLANCHNIC (L1+L2)
• Parasympathetic sensory (regulate reflex gut function):
– VAGUS NERVE
– PELVIC SPLANCHNIC NERVES (S2-S4)
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Thoracic Splanchnic Ns.
(T5-T12)
• Greater Splanchnic N.
(T5-T9)
• Lesser Splanchnic N.
(T10-T11)
• Least Splanchnic N.
(T12)
Thoracic splanchnic N. (T5-T12) - Sympathetic
Lumbar Splanchnic N. (L1, L2) - Sympathetic
Sacral Splanchnic N. Sympathetic
The autonomic nerves
are routed via plexuses
along the abdominal
aorta and its branches.
Pelvic Splanchnic N. (S2-S4) - Parasympathetic
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Innervation: the sensory fibres
are most important.
In the viscera:
Sensory fibres running with the
sympathetic mediate pain
Sensory fibres running with the
parasympathetic (vagus or
sacral) are involved in reflex
regulation of gut function
Autonomic Control of the Gut
Sympathetic
Parasympathetic(via vagus/pelvic S2-4)
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Para-sympathetic from vagusand sympathetic (T10-12) from Superior Mesentericplexus
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• Begins at the aortic hiatus in the diaphragm at T12 and ends by dividing into the right and left common iliac arteries at L4
• Common iliac artery divides into external and internal iliac arteries
• On its right side lie the IVC, cisterna chyli and azygos vein
• On its left side lies the left sympathetic trunk
Abdominal Aorta
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• Formed by the
union of common
iliac veins at L5
• Ascends on the
right side of the
aorta, passes thru
the caval foramen
(T8) and drains into
right atrium
• Tributaries:
Inferior Vena Cava
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1. Subcostal (T12)
2. Iliohypogastric (L1)
3. Ilioinguinal (L1)
4. Genitofemoral (L1,2)
5. Lateral Femoral Cutaneous
(L2,3)
6. Femoral (L2-L4)
7. Lumbar Sympathetic Ganglia
Somatic & Autonomic Nerves
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1. Celiac plexus
2. Superior mesenteric plexus
3. Inferior mesenteric plexus
4. Renal plexus
Components:
• pre- and post-ganglionic
sympathetic fibres
• visceral sensory
• pre-ganglionic
parasympathetic fibres
Aortic Plexus