ORAL AND MAXILLOFACIAL PATHOLOGY OOOO

e170 Abstracts February 2014

left retromolar area. Histological examination was diagnostic forSCC. These cases highlight the importance of monitoring treatedpatients in order to appropriately treat recurrences.

PE-196 - LOW-GRADE CENTRAL OSTEOSARCOMA INMANDIBLE: CASE REPORT. RENATA ACAY, WALTERNICCOLI-FILHO, VIVIAN NARANA RIBEIRO EL-ACHKAR,GABRIELA DE MORAIS GOUVÊA LIMA, ESTELAKAMINAGAKURA TANGO, YASMIN RODARTE CARVALHO,ANA LIA ANBINDER. UNESP - UNIVERSIDADE ESTAD-UAL PAULISTA/SÃO JOSÉ DOS CAMPOS.

Low-grade central osteosarcoma of the jaws is an extremelyrare lesion that cannot be diagnosed solely through histopatho-logical analysis because microscopically it presents few signs ofmalignancy. The definitive diagnosis depends on an evaluation ofthe clinical course and imaging. A good example of the interde-pendence among these aspects of diagnostic investigation is pre-sented. Woman, 48, was referred to the oral medicine service dueto a mixed radiolucent/radiopaque lesion with aggressive appear-ance and cortical erosion that affected the body and ramus of theright mandible. An incisional biopsy was performed to investigatethe preliminary clinical diagnosis of osteosarcoma. Histologically,the specimen consisted of a proliferation of spindle cells showingvery discrete pleomorphism in a fibrous stroma. Irregular andimmature osseous trabeculae with evident osteoid production,often surrounded by flat cells, were evident. Combining clinical,radiographic, and histopathological features, the diagnosis wascompatible with low-grade central osteosarcoma.

PE-197 - LOW-GRADE MUCOEPIDERMOID CARCI-NOMA OF MINOR SALIVARY GLAND: CASEREPORT. THAYNÁ MELO DE LIMA MORAIS, AMANDALAÍSA DE OLIVEIRA LIMA, MATHEUS HENRIQUEALVES DE LIMA, JÉSSYCA ÍTALA BARROS WANDERLEYDA SILVA, SONIA MARIA SOARES FERREIRA, PABLOAGUSTIN VARGAS, CAMILA MARIA BEDER RIBEIRO.CENTRO UNIVERSITÁRIO CESMAC.

Mucoepidermoid carcinoma (MEC) is a malignant glandularepithelial neoplasm. MEC is the most common salivary glandmalignancy in both adults and children and demonstrates a wide anduniform age distribution. There is a 3:2 female predilection, but ahigher female predominance for tongue and retromolar sites. Half ofthe tumors occur in themajor salivary glands, but theminor salivaryglands may also be affected. Most tumors present as firm, fixed,painless swellings. Dark-skinned young woman, 18, was referredwith complains of a “lump.” Intraorally there was a single normo-chromic node located in the left retromolar region. Biopsy wasperformed, and histological samples evidenced a low-grade MEC.The patient was referred to a head and neck surgeon to remove thelesion. Currently, the patient has been monitored for 1month withno signs of recurrence.We emphasize the importance of diagnosingmalignant minor salivary gland lesions in young patients.

PE-198 - LYMPHANGIOMA IN THE TONGUE: CLIN-ICAL FOLLOW-UP OF 8 YEARS AND IMMUNOHIS-TOCHEMICAL STAINING WITH D2-40. CLARISSACASTRO GALVÃO MEDEIROS, JULIANA ANDRADECARDOSO, FERNANDA GONÇALVES SALUM, KARENCHERUBINI, MARIA ANTONIA ZANCANARO DEFIGUEIREDO. DIVISION OF ORAL MEDICINE, PUCRS,PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDEDO SUL, BRAZIL.

Lymphangiomas are benign lymphatic malformations thatfrequently affect the head and neck region. Oral lesions occurmostly in the anterior two thirds of the tongue and producemacroglossia. A lymphangioma in the tongue was clinically fol-lowed-up for 8 years. Girl, 3, was referred to the oral medicineunit for assessment of a painless enlargement at the right side ofthe tongue. A nodule measuring 2.0 � 1.0 cm was noticed atclinical evaluation. During the first 5 years of follow-up there wasno enlargement of the lesion, which was confirmed by two ul-trasonography exams. After 7 years the nodule increased to 2.5 �1.5 cm and the patient reported speech problems due to the lesiongrowth. Surgery was performed, and the histopathologicalexamination showed several large lymphatic vessels filled withlymph below the epithelium. Immunostaining with D2-40, alymphatic vessel-reactive antibody, was positive.

PE-199 - MAJOR SALIVARY GLAND CYSTADENOMA:CASE REPORT. DIANA XAVIER DE BARROS PADILHA,CAMILA MARIA BEDER RIBEIRO, RICARDO VIANABESSA NOGUEIRA, DARLAN SILVA DE OLIVEIRA,KÁTIA VALÉRIA LIMA DE OLIVEIRA LEITE, SONIAMARIA SOARES FERREIRA, AMANDA LAÍSA DEOLIVEIRA LIMA. CENTRO UNIVERSITÁRIO CESMAC.

Cystadenoma is a rare benign epithelial tumor commonlylocated in minor salivary gland regions that produces smooth-surfaced nodules. There is a female predilection and the mostcommon age is about 57 years. Histopathologically, it is char-acterized by predominantly multicystic growth with adenomatousproliferation of the epithelium. The epithelial lining is frequentlypapillary and rarely mucinous. Woman, 58, complained of aslowly growing large painless mass on the left side of her face.Intraoral examination noted a well-defined, homogeneous,smooth-surfaced nodule/mass in the parotid duct region. Patho-logical cuts revealed benign glandular lesion with multiple smallcystic spaces. The lumen contained eosinophilic material withscattered epithelial inflammatory cells and cuboidal material lin-ing the epithelium. A diagnosis of major salivary gland cys-tadenoma was suggested. After 8 months of follow-up, norecurrence was observed and the patient had no major complains.

PE-200 - MALIGNANT TRANSFORMATION OF ANORAL LICHEN PLANUS IN A 74- YEAR-OLD WOMAN.ANNA TORREZANI, ANA PAULA CANDIDO DOS SANTOS,CAMILA DE BARROS GALLO, ÉRICA PATRÍCIO,NORBERTO NOBUO SUGAYA, FABIO DAUMAS NUNES,CELSO AUGUSTO LEMOS JUNIOR. FACULDADE DEODONTOLOGIA DA USP.

Oral lichen planus (OLP) is a chronic inflammatory disease thataffects around 1% to 2% of the population. It affects mainly womenbetween ages 30 and 60 years. The most frequently affectedanatomical regions in the oral cavity are the buccal mucosa, gingiva,and lateral borders of the tongue, all bilaterally. In about 0.2% ofOLP cases, the lesion can transform into a carcinoma, mainly asso-ciated with atrophic lesions, erosion, and plaque. Leukodermicwoman, 74, had lesions suggestive of OLP for 4 years. OLP wasconfirmed by histological analysis. After 8 months of follow up, alesion in the left lingual alveolar ridge was suggestive of carcinoma.Histopathological examination confirmed squamous cell carcinoma.An oncologic surgeon removed the alveolar ridge, mouth floor, andborder of the tongue, which were confirmed by frozen biopsy to becarcinoma. No adjuvant therapy was necessary, and the patient re-mains free of disease after 3 months.