• LBM loss increases with age3-7

• Sarcopenia is the loss of skeletal muscle mass and function, which occurs with advancing

age and compromises recovery and survival8

Complications increase with greater LBM loss1

Loss of lean body mass (LBM) and strength is associated with malnutrition and is also evident with aging3-7

90%

80%

70%

60%

50%

40%

25 YRS 40 YRS 70 YRS 80 YRS

ZO

NE

WH

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ISK

O

F D

EA

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IS

HIG

H

% O

F M

US

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PER DECADE LOSS FROM 40 TO 70

PER DECADE LOSS AFTER AGE 70

AGE

8%

LOSS

15%

LOSS

• LBM loss can affect strength, walking, rising out of a chair, climbing stairs, and risk of falls2

100%

50%

30%

10%

% LOSS OF LEAN BODY MASS

- Impaired immunity- Increased infection

- Decreased healing

- Too weak to sit- Increased risk of pneumonia- Wound healing stops

- Death, usually due to pneumonia

10%

10%

30%

50%

100%

% M

OR

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20% 30% 40%

To learn more about how LBM loss and sarcopenia affect your patients, visit fightsarcopenia.com, or contact your Abbott sales representative.

Loss of Lean Body Mass Can Lead to Functional Decline1,2

HMB can help reduce protein degradation in skeletal muscle cells.11

*Study Design A randomized, controlled trial evaluated the effect of HMB on muscle decline during 10 days of complete bed rest in women 60 to 79 years of age. Subjects were randomized to receive HMB (n=11) or control (n=8) for 5 days before and 8 weeks after bed rest.

References: 1. Demling RH. Eplasty. 2009;9:65-94. 2. Morley JE, et al. J Cachexia Sarcopenia Muscle. 2014;5:253-259. 3. Baier S, et al. JPEN J Parenter Enteral Nutr. 2009;33:71-82. 4. Flakoll P, et al. Nutrition. 2004;20(5):445-451. 5. Grimby G, et al. Acta Physiol Scand. 1982;115:125-134. 6. Janssen I, et al. J Appl Physiol. 2000;89:81-88. 7. Vandewoude MF, et al. J Aging Res. 2012;2012:651570. Epub 2012 Sep 13. 8. Cruz-Jentoft AJ, et al. Age Ageing. 2014;43:748-759. 9. Data on file. Abbott Nutrition. 10. Deutz NE, et al. A randomized, placebo-controlled clinical trial of readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutrition supplement. ASPEN Clinical Nutrition Week 2016. Austin, TX. 11. Eley HL, et al. Am J Physiol Endocrinol Metab. 2008;295:E1417-E1426. 12. Deutz NE, et al. Clin Nutr. 2013;32:704-712.

©2015 Abbott Laboratories 150585/December 2015 LITHO IN USA

HMB preserves muscle in older adults12*

HMB +PROTEIN

LO

SS

OF

LE

AN

BO

DY

MA

SS

(L

BS

.)

-2.05 kg/-4.5 lbs P=0.02

-0.17 kg/-0.4 lbs P=0.23

Control

-5

-4

-3

-2

-1

0HMB

Less muscle loss with HMB

12X

#Doctor

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