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High quality, cost effective contract fermentation and manufacturing services.
Location and PurposeFermentation is a critical service for biotechnology, biopharmaceutical and biologics industries. Located on Utah State University’s Innovation Campus, the Synthetic Biomanufacturing Facility is designed and staffed to optimize and scale-up commercial development and production of bioproducts. The facility provides production capabilities for statewide university research and private industry through state-of-the-art equipment and technical support, including a world-class fermentation lab.
The primary purpose of the fermentation lab is to generate substantial quantities of biomolecules for commercialization and scale-up performance evaluation. The capabilities of this facility provide scale-up optimization of fermentation bioproducts that can be grown and analyzed under a variety of growth conditions for maximum product yield and quality.
Planning for the future, the lab design allows room for the expansion and addition of equipment as demand increases.
Contract Manufacturing and Equipment UseAvailable for contract manufacturing and equipment use, the Synthetic Biomanufacturing Facility offers a wide range of lab-to-pilot scale fermenters for process development, testing and production. The lab provides two New Brunswick BioFlo Pro 400 liter fermenters to allow process optimization with a variety of setup options and data collection resources. A 100 liter New Brunswick BioFlo 610 fermentation system provides steam-in-place capability, is fully automated and is available stand-alone or as a seed reactor. Several sizes of centrifuges and tangential flow filtration devices are available for cell and product recovery.
GEA Westfalia TSE 10 Clarifier
Major Equipment2L reactor w/ BioFlo 115 system100L reactor w/ BioFlo 610 system400L reactor w/ BioFlo Pro systemÄKTA Chromatography systemsCEPA Z-41 CentrifugeGEA NS3006H HomogenizerGEA Westfalia TSE 10 ClarifierInnova 4300 IncubatorSpectrum Labs KTF 1000 TFFThermoFisher Lynx 6000 CentrifugeThermoFisher NanoDrop 1000ThermoFisher Vaquish Flex HPLC
Additional EquipmentFloor Centrifuge 6 L capacityMicro DeBEE High Pressure Homogenizer 45,000 psig 15 L/HrStainless Steel Spray dryer with Inert Gas loop 3.5 L/HrLyophilizer 18 L capacitySanitary CIP Pump Cart 10 HP
New Brunswick BioFlo Pro 400L
New Brunswick BioFlo Pro
New Brunswick BioFlo 610 100L
Jordan MorleyResearch Engineer
Contract Fermentation and Manufacturing ServicesThe Synthetic Biomanufacturing Facility offers contract fermentation and manufacturing services to our partners in the biotechnology, biopharmaceutical and biologics industries. We support our customers in developing and scaling up the process from lab to pilot-scale to commercial manufacturing, with strict adherence for batch and sterilization protocols. Our facility is well equipped to provide bench-top to pilot-scale fermentation services, including your downstream process requirements.
Our services span many organisms, stages, industries and production volumes including microbial fermentation of bacteria, actinomycetes, yeast and fungi, small- and large-scale contract fermentation, fermentation process validation, distribution support and secure manufacturing supply.
Cost Effective ServicesWhether your needs are development or commercial services, we provide highly competitive services designed to support your projects on small to large scales. Please contact us to learn how the Synthetic Biomanufacturing Facility can work with your company to develop and scale-up your fermentation process, adding the downstream separation processes, if needed, and help you reach your commercial manufacturing goals. We are here to assist you in transitioning from research to commercial manufacturing and in converting your innovative ideas into practice.
Synthetic Biomanufacturing Facility
Sridhar VakalapudiDirector
rgs.usu.edu/sbf | (435) 797-5540
1700 North Research Park Way, Suite BNorth Logan, Utah 84341
