Lissod Book for Doctors

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    WE ARE 5 YEARS O

    ZINA

    MEMORIAL

    LISSOD

    HOSPITAL

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    5 years in Ukraine

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    The latest achievements of the world oncology

    Advanced technologies for diagnosis and treatment

    The leading international and Ukrainian specialists

    Modern equipment

    European level of comfort

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    Dear friends!

    Cancer - not a verdict but a diagnosis, Weve beatencancer, Cancer can be cured these slogans are rather

    common both in printed and electronic media. But the

    Cancer registry data tell a different story: even though

    cancer is a diagnosis, and weve beaten and cured,

    there are more people dying of cancer in Ukraine than in

    the developed Western countries. They die of a potentially

    curable illness, while observance of certain conditions

    could save many lives. Those are not mere conditions for

    LISSOD, they are the laws to which activities of the clinic

    have been subjected since its establishment. I want you

    to know about them because competent treatment of

    information is life-saving today.

    Required are knowledge and experience of physicians, their

    non-indifferent attitude to the patient, a comprehensive

    approach to treatment, modern equipment, use of

    innovative technologies and international medical and

    diagnostic standards. The indispensable combination

    of all of these factors lies in the heart of the hospital

    activities. Many Ukrainian health facilities today have

    qualied physicians, some acquire modern equipment,

    and some of them try introducing the latest technologies.

    But the undertakings are not always successful since

    > Hospital of the Third Millennium

    Alla Vinnytska,

    LISSOD Chief physician,

    MDMember of the European Society

    for Medical Oncology;

    European Society of

    Gynecological Oncology;

    American Society of Clinical

    Oncology.

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    God entrusted doctor to treat,not to predict.

    Ignore predictions,think only positive.

    > about the hospital

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    new technologies without modern equipment stand

    to nothing, while good equipment managed by poorly

    trained specialists will not work efciently. We however

    managed to combine all the components for successful

    ght against cancer. The leading specialists from Israel

    work together in one hospital with the Ukrainian physicians

    who have undergone training at major cancer centers

    in Europe, America and Asia. Any person turning to us

    for help is directed to high-class cancer professionals.

    An interdisciplinary Tumor Board takes the right rst

    decision that determines the entire further course oftreatment. In their work the LISSOD physicians are guided

    by international protocols, using world experience and

    principles of evidence-based medicine.

    Everything is aimed at a successful outcome: involvement

    of specialists from different countries, the use of modern

    equipment and the latest achievements of the world

    oncology. Desire and ability of the clinic staff to help the

    patient in ghting the disease is the key to success. Cancer -not a verdict but a diagnosis is not a slogan for LISSOD,

    it is the result of a 5-year work in Ukraine. If you or your

    loved one was such diagnosed, please know that it is not

    the end of life but its new turn; a challenge that can and is

    to be overcome. Do not despair, start treatment as soon as

    possible since time is the vital factor in cancer treatment.

    On our part, we will do our utmost for your recovery.

    > about the hospital

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    The hospital can provide

    consultations and treatment of 200

    patients per day. At the spacious

    lobby every visitor is welcomed by

    friendly staff. Computer system

    allows for accurate planning of

    schedule of all consulting rooms

    and departments of the hospital

    and our patients can always

    choose convenient time for their

    visit. Thus you will not wasteyour time in a queue. There is a

    bank ofce in the lobby to make

    payments in any convenient way.

    A cozy bar offers wide range of

    drinks and snacks.

    > about the hospital

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    Clinical oncologist is neither a surgeon nor a

    chemo- or radiotherapist. It is a specialist withprofound knowledge of modern methods

    of cancer diagnosis and treatment, tumors

    biology and immunology, molecular biology;

    well-grounded in pathological anatomy and

    histopathology basics as well as instrumental

    and laboratory methods of research. Clinical

    oncologist makes a plan of examinations, makes

    diagnosis and determines disease stage on the

    basis of test results; predicts the disease course, determines the therapeutic tactics taking into account

    the sensitivity of tumor and the feasibility of radio-, chemo-, biotherapy and / or surgical treatment;

    well-grounded in rehabilitation basics. It is far from being the complete list of knowledge and skills the

    LISSOD clinical oncologists possess. Our patients rst appointment is held with the leading foreign

    oncologists as well as high-class Ukrainian physicians who have undergone training at major cancer

    centers in Europe and Israel.

    In difcult and controversial cases we always gather Tumor Board involving several clinical oncologists,

    chemo-, radiotherapists and histopathologists. It allows excluding the possibility of human mistake.

    With the use of the hospital telecommunications system we hold consultations with the world leading

    oncologists in real time.

    Individual approach to each patient is the core principle of LISSOD. An administrator, available 24/7

    for all issues related to diagnosis and treatment, is assigned to a patient from the very rst visit. Great

    importance is also attached to careful examination of each patient. Just to mention the rst consultation -

    at our hospital it lasts up to 60 minutes.

    > Consultation Department

    > about the hospital

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    Over the 5 years of the hospital existence more than

    10 000 patients have been received and more than

    15 000 consultations held, including medical record

    reviews (for people, whose relatives couldnt come

    to the hospital).

    > about the hospital

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    > the LISSOD leading doctors

    ABRAHAM KUTEN

    MD, Professor (Israel)Head of Advisory Board of LISSOD.

    Director of Department of Oncology of Rambam Medical Center (Haifa, Israel).

    Member of American Society of Clinical Oncology; American Society for Therapeutic

    Radiology and Oncology, American Brachytherapy Society, European Society of

    Medical Oncology, European Society for Therapeutic Radiology and Oncology,

    European Association for Cancer Research, Israel Society for Clinical Oncology and

    Radiotherapy, Israeli Society of Surgical Oncology, Israel Society of Otolaryngology

    Head and Neck Surgery, and International Psycho-Oncology Society.

    ZVI BERNSTEIN

    MD, IsraelHead of Clinical Oncology Department of LISSOD.

    Dr. Bernstein made a signicant contribution to the development of radiotherapy,

    having worked for many years in the Department of Oncology of Rambam Medical

    Center (Haifa, Israel). He formulated the fundamental principles in planning three-

    dimensional therapy of gastric cancer. Dr. Bernstein's works are used as guidelines by

    the European Organization for Research and Treatment of Cancer (EORTC). In 2008,

    Dr. Bernstein was awarded the honorary certicate of the Israel Cancer Association

    for his contribution to the development of oncology.

    ELIZAVETA DUDNIK-ILSTEIN

    MD, IsraelClinical oncologist

    Worked as an oncology consultant at the following clinics and departments:

    Hillel Yaffe Medical Center (Hadera , Israel), Internal Medicine Department and

    Thoracic Surgery Department of the Rambam Medical Center (Haifa, Israel).

    Member of Rambam clinics multidisciplinary cancer conferences on lung cancer.

    Active member of the following professional associations: 2011-2012 - European

    Association for Cancer Research; 2006 - 2012 - Israel Society for Clinical and

    Radiation Oncology.

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    > the LISSOD leading doctors

    IGOR REUT

    MD, IsraelClinical oncologist

    For many years has worked as a clinical oncologist at Rambam Medical Center (Haifa,

    Israel). Active member of the following professional associations: Israel Medical

    Association (IMA), Israel Society for Clinical Oncology and Radiotherapy (ISCORT);

    European

    Organization for Research and Treatment of Cancer (EORTC); Rare Cancer Network

    (RCN). Specialization: Clinical Oncology.

    SERGEY BAIDO

    MD, PhD, Docent,Doctor of the highest category

    In 1994 he graduated with honors from the Poltava State Medical University

    and undergone clinical internship at the faculty of surgical gastroenterology and

    hepatology of St.-Petersburg Medical Academy of Postgraduate Studies. In 1997

    immediately after internship he defended his PhD thesis on Methodological aspects

    of endovideosurgical formation of organ anastomoses in portal hypertension.

    ANDREY ZHIGULIN

    MD,Doctor of the highest category

    Head of the Department of Surgery of LISSOD. Member of European Society of

    Surgical Oncology. In 1993 he graduated with honors from the Bogomolets NationalMedical University. After internship in surgery he worked in the Gastrointestinal

    Bleeding Center at Kiev City Hospital #12 under the supervision of Prof. V.D. Bratus

    and Prof. P.D. Fomin.

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    > Medical Oncology and Radiotherapy

    Over the last 2-3 years there has been a signicant

    progress in cancer treatment, comparable to a revolution

    in oncology. At present we can tell with condence that

    more than 60% of patients can be cured. This is true for

    absolutely all cancer patients, not only for patients with

    early stages of cancer (data of the U.S. National Cancer

    Institute). These results can be achieved only through

    the use of international medical standards in cancer

    treatment. Full application thereof at LISSOD places

    Ukraine in one row with the most developed Western

    countries.

    > medical oncology and radiotherapy

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    > medical oncology and radiotherapy

    In radiotherapy we use linear accelerators of the latest

    generation. The use of linear accelerators in combination

    with three-dimensional planning, involving computed

    tomography and sophisticated computer programs

    enables getting a three-dimensional image of the tumor

    and healthy organs. The necessary dose of radiation

    is focused on the tumor while the inuence on the

    surrounding organs and tissues is minimized. Therefore,

    the frequency of side effects and complications after

    radiation therapy is gradually reduced.

    Ensuring quality radiotherapy treatment requires

    not only linear accelerators but also specially trained

    specialists. For 5 years already, starting from March

    2007 a team of highly qualied radiation therapists,

    technicians, medical physicists and engineers trained

    abroad has been working in LISSOD.

    Electron irradiation provides accurate treatment of

    supercial tumors without damaging organs located

    deeply into the body. Additional advantage of this type

    of radiation therapy is the possibility of intraoperative

    radiation.

    In terms of air cleanliness, the linear accelerator rooms

    are built on the level with modern operating rooms,

    allowing for the transfer of the patient under anesthesia

    for irradiation of the tumor bed. Thus, the surrounding

    tissues are not damaged and chances of cure increase

    signicantly. Such system is used in treatment of breast

    cancer, pancreatic cancer, sarcomas of soft tissues, ofthe pelvic organs (rectum, cervix), etc. For instance, in

    the case of breast cancer the patient can avoid everyday

    treatment for 5-7 weeks: the long course is replaced by

    a single session of irradiation during the operation.

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    > medical oncology and radiotherapy

    Only a few health facilities in Europe have such a

    technology and this fact puts LISSOD on the leve

    with the most prestige cancer clinics.

    The hospital provides brachytherapy involving

    high-power sources, namely iridium. The source is

    delivered to the tumor by remote control without

    a touch of hand, ensuring full radiation safety

    for the patient. Brachytherapy together with

    computer planning provide high cure rate with

    minimal side effects in comparison with outdated

    technologies. Uterine and cervical cancer, breast

    cancer, prostate cancer, head and neck malignant

    tumors as well as soft tissue sarcomas (without the

    need for limbs amputation) - brachytherapy treats

    these tumors promptly, effectively and without

    hospitalization. Specially equipped rooms with

    the operating rooms level of air cleanliness allows

    to prescribe high-dose chemotherapy when

    necessary.

    The strategic idea of clinical oncology at LISSOD is

    multidisciplinary planning of the medical process

    involving surgery, radiotherapy, chemotherapy,

    hormonal and immunological treatments. This

    approach enables us to closely follow the principle

    of organ preservation in the treatment of cancer

    without compromising its radicalism.

    Over the 5 years of LISSOD functioning

    more than 20 000 sessions of radiotherapyhave been carried out.

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    > Surgery

    > surgery

    Operating rooms are Class 10000 and equipped with a sophisticated system of

    automatic removal of narcotic gases. The work of top-class specialists and the

    use of the latest equipment allow performing general and laparoscopic surgeries

    of any complexity at LISSOD. Advanced anesthesia and respiratory devices with

    the use of the latest generation screens provide accurate monitoring of patients

    organs and systems condition during the operation, which, in turn, enables the

    use of minimally sufcient anesthesia, reducing the frequency of complications

    both during and after surgery.

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    The vast majority of operations

    (99%) are performed through

    laparoscopic access. Advantages

    of laparoscopic operations are as

    follows:

    operations in the abdomen or chest

    are performed through 3 to 5 small

    incisions (usually 0.51 cm) as opposed

    to the larger incision (7 to 30 cm)

    less pain, leading to less pain

    medication needed

    no need for post-operative bed rest

    faster return to everyday living

    Laparoscopic accesses enable

    simultaneous multi-organ surgery.

    >

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    The Intensive Care Unit is equipped in accordance

    with the leading world standards in this eld.

    Mobile equipment makes it possible to apply

    minimal anesthesia for complete pain and

    discomfort relief during diagnostic procedures,

    which are commonly thought to be painfu

    and unpleasant (bronchoscopy, gastroscopy,

    colonoscopy, prostate examination, gynecological

    examinations, etc.).

    > Intensive Care Unit

    > intensive care unit

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    > breast care

    The frst Modern Breast Center in Ukraine was set

    up on the LISSOD basis. High qualied specialists of

    different elds - clinical oncologists, oncology and plastic

    surgeons, breast physicians, radio- and chemotherapists,

    histopathologists and gynecologists - are involved in its

    work. The most advanced technologies and standards are

    used in the Center. In particular, the Stereotactic Breast

    Biopsy Unit by Lorad (USA) allows detecting even minimal

    deviations from the norm in the three-dimensional image

    in real time. A special Vacuum-Assisted Breast Biopsy

    device enables removal of benign breast tumors up to 2

    cm without surgical interference. Oncotyping (the latest

    test method) helps determining the efciency of different

    treatment methods for each patient. The treatment thus

    gets more individual - inuence on the organism reduces

    while efciency stays the same.

    Principles of plastic surgery as well as help of plastic

    surgeons themselves are used for preservation and

    restoration of breasts in their full attractiveness. The

    Centers specialists were the rst in Ukraine to introducethe organ preservation technique of sentinel lymph node

    biopsy, which makes it possible to preserve the unaffected

    lymph nodes and prevent such complications as chronic

    lymphostasis. They were the rst to successfully use the

    radio frequency identication of nonpalpable breast

    cancer, with which even the smallest tumors are removed

    accurately and completely. The radicality of tumor removal

    during operations is always controlled.

    More than 250 different breast operations have

    been performed at the LISSOD Breast Center.

    > Breast Care

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    > urology

    > Urology

    The ultrasound-guided prostate biopsy is held

    when pathological changes in prostate are

    detected during the nger rectal examination

    or in case of increased level of PSA tumor

    marker in blood. Special equipment with a

    thin needle is used to differentiate benign

    from malignant prostatic hyperplasia. This

    absolutely painless examination is done

    on an outpatient basis with the use of the

    latest achievements of minimally invasive

    anesthesia.

    > Gynecology

    The Department of Gynecology performs

    tests to detect malignant tumors and pre-

    cancerous diseases. The LISSOD principle

    of gynecological cancer treatment lies in

    combination of the necessary oncological

    radicality with the organ preservation

    treatment. The clinical staging performed

    during the operation allows choosing the

    most optimal protocol for post-operative

    care.

    All painful procedures are performed with

    the use of minimal anesthesia.

    > gynecology

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    The Endoscopy Department is equipped with the most advanced equipment and is organized

    on the level with the best endoscopy departments of the Western hospitals. What is most

    important for patients - all endoscopic observations including invasive ones are performed

    with the use of anesthesia, thus eliminating unpleasant feelings. The video endoscopes used

    in our hospital have minimum diameter, while video cameras improving the image quality

    allow detecting any deviations from the norm. We also use echo-endoscopes which enable

    the puncture of different neoplasms. LISSOD patients can undergo endosonography with the

    possibility of ne-needle aspiration biopsy (an endoscopic ultrasound observation of organs

    in chest and abdomen directly through the stomach or esophagus). This technique is truly

    revolutionary and serves as a substitution to an open biopsy.

    > Endoscopy

    > endoscopy

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    > Computed Tomography

    > computed tomography

    The computed tomography (CT) is performed in accordance with the world

    leading protocols. The department is equipped with Philips multi-image CT

    scanner and a MedRad contrast media injector. CT-tests of the whole body

    are performed with the use of different techniques depending on medical

    necessity. CT-tests are normally done with intravenous and oral contrast unless

    there any contraindications. Apart from standard CT-tests CT-urography,

    CT-enterography, lung cancer screening are performed. CT-guided biopsies of

    different complexity are carried out.

    Over the 5 years of LISSOD work more than 4 000 CT-tests have been

    performed.

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    At the Nuclear Medicine Department

    with the use of gamma-camera

    dynamic planar and three-dimensional

    tomography tests are held. These tests

    detect additionaly 30 % of pathological

    changes comparing to the regular bone

    scintiography.

    Lymphoscintigraphy, for instance, is

    used to detect affected lymph nodes

    during the operation in order to avoid

    the unnecessary surgical invasion and

    minimize post-operative complications.

    Modern scintillation gamma-camera

    allows getting, storing and processing

    images of a separate organ, system or

    the whole body in the static, dynamic

    and graphical modes.

    > Nuclear Medicine

    > nuclear medicine

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    > Chemotherapy Day Unit

    The Chemotherapy Day Unit provides the most

    advanced chemotherapy without hospitalization

    In order to ensure the maximum comfort we

    use specialized chairs with an option of body

    massage. Every patient can watch the favorite

    movie or listen to music via personal dvd-device

    during the chemotherapy.

    > chemotherapy

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    Research in morbid anatomy is the cornerstone of oncology.

    Its results show whether the patient has cancer or not, show

    the form of disease. Mistakes here may turn fatal if treatment

    starts without necessity for it or if nothing is done when

    there is urgent need for it. Histological conclusion is the

    guidance for the oncologist in choosing treatment tactics,

    its components, and chemotherapy agents.

    Great attention is attached in LISSOD to the verication

    of the oncological diagnosis. The verication is held at

    the world leading morbid anatomy laboratories in Israel

    and Germany, whereto all the tissues samples received

    during operations, biopsies (endoscopic, breast, etc.), and

    aspiration punctures, are sent.

    The samples of tissues removed in the course of operations

    are sent to the LISSOD morbid anatomy laboratory

    equipped with modern facilities for express diagnosis for

    cancer cells, which are invisible to surgeon. It allows the

    surgeon to remove the minimum of healthy tissues, and on

    the other hand to reduce the disease relapse and metastases

    appearance.

    More than 40 000 laboratory research has

    been carried out over the 5 years of the LISSOD

    existence.

    > Morbid Anatomy

    > morbid anatomy

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    Rehabilitation program is an individually-tailored complex of recovery

    procedures in different areas. It is guided by highly qualied specialists

    and is an integral part of the complete cancer care cycle

    > Rehabilitation Program

    > rehabilitation program

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    Medical support

    Individual rehabilitation plan as welas the treatment plan is devised by

    the interdisciplinary Tumor Board.

    Endocrinologists, cardiologists,

    urologists, gastroenterologists,

    physiotherapists, exercise phy-

    siologists get involved in the

    recovery process depending on

    the problems concomitant to the

    disease.

    > rehabilitation program

    A general practitioner (GP) and an exercise therapist work permanently with our patients. Their

    help is an important component of the comprehensive treatment.

    Depending on the situation the GP provides recommendations as for the maintenance treatment

    of cardiovascular, respiratory and gastroenterological diseases. Our patients can get dietary

    recommendations for many illnesses such as diabetes mellitus, heart diseases, diseases of the GIT, etc.

    All the rehabilitation therapeutic measures planned take into account the oncological treatment.

    Problems connected with lack of exercise, excess weight, osteochondrosis, ischemic heart disease may

    arise in post-operative patients and those limited in physical activity as a result of the underlying disease

    complications. That is when the help of an exercise therapist is required. Therapeutic exercises are

    therefore very important in post-operative period.

    The exercises can be both individual and in groups. The exercise therapist takes into consideration the

    disease features and character, and establishes the intensity. Exercises reduce the recovery time.

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    Psychological support

    We believe that success in cancer treatment is directly related to the emotional state of the patient.What is more, patients relatives are often in need of such support. Restraint and calmness, awareness,

    adequate view of the situation and interaction with doctors is very important to them. Our 5-year

    experience and that of the leading Western hospitals proves that psychological support multiplies the

    treatment results.

    The psychological support in LISSOD is free of charge and is an important part of comprehensive

    treatment.

    Professional psychologist holds private and group counseling.

    The psychological support groups work successfully at the clinic and are open for all comers.

    Specialists in psychology consult patients relatives on a regular basis. They help them to cope with

    anxiety and to build relations in the way to provide support to their loved ones.

    Psychological support helps the recovery of patients by lling their lives with warmth, understanding,

    sense and condence.

    > rehabilitation program

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    Aside from classic rehabilitation procedures the LISSOD

    patients can take a course of Ayurvedic massages.

    Ayurveda (knowledge of life in Sanskrit) - is a Hindu system

    of health procedures aimed at physical and emotional

    recovery of the person. The practice of Ayurveda therapy

    is adopted by the World Health Organization and is widely

    used in the USA, the EU countries, etc.

    Ayurvedic massages promote vigor and relieve stiffness,

    improve emotional state, blood circulation and lymphatic

    drainage, accelerate toxin elimination (which is especiallyimportant during the course of radio- and chemotherapy).

    Having general positive impact on organism the massages

    help to endure the cancer treatment easier and to recover

    faster.

    Prescription for Ayurvedic massages at LISSOD is made

    only under control of the clinical oncologist while the

    manipulations are performed by high class specialists

    from India.This allows accounting for all possiblecontraindications, ensuring maximum effect of treatment

    and recovery procedures.

    > rehabilitation program

    > Ayurvedic Therapy

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    > Domiciliary Care

    > domiciliary care

    The more weak and vulnerable a person is the more professional care is needed. Realizing it and due to

    numerous requests of patients relatives the LISSOD organized the Domiciliary Care service.

    Domiciliary care services

    Consultations at home. Doctors of different proles are available depending on the needs of the

    patient.

    Care service, medical care at home.

    Comprehensive home care for both oncologic and non-oncologic patients, care for the elderly.

    Delivery and assistance in purchasing patient-care equipment.

    Day hospital at home.

    All the medical manipulations are performed by the staff in accordance with doctors prescriptions and

    are thoroughly registered.

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    > Comfort

    > comfort

    We have created conditions for the best psychological and physical comfort,

    which is critically important for the successful diagnosis and treatment.

    A lovely park, single-patient rooms of high-class hotel rooms level, meals

    according to the wishes of patients and specialists recommendations, personal

    approach to each patient this is how our hospital breaks common stereotypes

    existing about treatment facilities.

    The surrounding nature also inuences positively the LISSOD is situated in

    a picturesque suburb of Kiev near Koncha-Zaspa Reserve.

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    > comfort

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    ZINA

    MEMORIAL

    LISSOD

    HOSPITAL

    LISSO information center:

    tel.: 0 800 500 110(toll-free for calls from

    fixed-line phones in Ukraine);

    tel.: +38 044 520 94 00

    e-mail:

    [email protected]

    Follow us on:

    www.facebook.com/LI

    @LISOD_clinic

    www.lissod.com