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Imaging with Positron Emission Tomography/ Computed Tomography (PET/CT)
Lisa Rhoden (RT)(R) B.S. CNMT
PETPET permits investigation and comparison of
events occurring at the molecular and cellular level.This data is not attainable by other modalities.
PET is especially useful in the detection of cancer, coronary heart disease, and brain disease.
The basis of PET is the positronThe positron is a positively charged beta particle
emitted from neutron-poor radionuclides.The result of this emission are annihilation
photons that create 2 gamma rays of exactly 511 keV each, at 180 degrees to each other.
Positron Decay
Annihilation - two photons
-+
511 keV
511 keV
180oPositronium
For more on Positron Decay click
PET/CT vs. PETThe ability to have the CT localization makes
interpretations more accurate PET/CT has advantages to the patient in
making the acquisition time shorterThere is more accurate attenuation
correction with PET/CT
PET/CT Machine
Protocol:Dose Receiving
•Upon receiving a dose shipment from the pharmacy, the technologist must check it in
•This includes measuring the radioactivity in mR at the surface of the box and at one meter away.
•All measurements are recorded and kept
Protocol: Patient Prep (at UAMS)Patient is to be held
NPO (with the exception of water) a minimum of six hours prior to injection time
No insulin or Dextrose-5 should be given to the patient for a minimum of six hours prior to injection
The patient may receive 5-10 mg of Valium before the injection is given
The patient should be made comfortable and relaxed
Did the patient follow the prep
correctly? YES NO
Protocol: Blood Glucose LevelA blood glucose level will be obtained prior to
injection and recordedOptimum blood glucose level is below 150
mg/dL
Below 150 mg/dL
Above 150 mg/dL
Select the patient’s blood
glucose level
Next: Assay the Dose
The tech will then do background counts and a wipe test
Next the dose will be assayed, or measured for radioactivity in the dose calibrator
Protocol: Isotope InjectionAn IV will be started and used to administer the
radioactive tracerPatient will wait 2-3 hours to allow the isotope to
be taken into the cells
Protocol Cont.Patient will drink
approximately 300 cc of contrast containing Omnipaque (iohexol) 300 mgI/ml
Remove metallic objects
Empty bladder
Protocol Cont.Position for scanningPatient position will be determined based
on area being scanned
Data Acquisition and Processing
Colorectal Carcinoma
CT PET FUSED
Breast Cancer
CT PET Fused
Review Basic PET Process
Isotopeproduction(cyclotron)
Tracerlabeling
(radiochemistry)
Tracerinjection &
data acquisition
Imagereconstruction Interpretation
Datasynthesis
Thank you for your time
Questions? Want more? For questions or
concerns regarding PET/CT scanning and procedures please send me an email by clicking the button below
If you would like more information on this topic and other related topics, please go to the website by clicking the button below