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LIPID LINEBACKERS. Lipid Linebackers: Tackling Diabetes One Fatty Acid at a Time. Kayla Johansen and Tiffany Sweet Introduction to Engineering and Design April 2013. Nanotechnology: Tiny but Mighty. What is it?. Molecular scale Bottom-up Atomic precision Molecular manufacturing - PowerPoint PPT Presentation
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Lipid Linebackers: Tackling Diabetes One Fatty Acid at a Time
Kayla Johansen and Tiffany SweetIntroduction to Engineering and Design
April 2013
What is it?
• Molecular scale• Bottom-up• Atomic precision• Molecular manufacturing• Personal nanofactories• Richard Feynman “I want to build a billion tiny factories, models of
each other, which are manufacturing simultaneously.” –Robert Feynman
Bottom Up Philosophy
• Building up• Not cutting down• Allows for smaller items• Layer by layer• Atom by atom• Like construction of a house• 3D printer
Where’s it Being Used?
• Medicine• Sunscreen• Tennis rackets• Cell phones• Frying pans• Computers• TV screens
Limitations Without Nanotechnology
• Top-down method• Size limits• Light wavesNow you can….• Build up• Atom by atom• Smaller than microscopic
Nanoparticles
• Less than 100 nm• Transmission electron microscope• Magnifies 1,000,000 times• Mechanochemistry• Vacuums• Comparable to enzymes
Problems
• Bad-natured uses• Grey goo• Another “Cold War”• Disruption of economy• Damage to environment• Black market trade
My Definition• Revolutionary tactic• Innovative• Divergent thinking• Smaller than small• World-changing• Life-changing• Atom-based
• Spin on chemistry• Build, not cut• Countless benefits• Lots of issues• Monitoring needed
WOW!
How Could it Impact my Lifestyle?
• Convenience– Cheaper computers– Better processors
• Improved medicines– Improved research– Faster diagnostics
• Improved health– Less pollution– Solar energy
Nanotechnology is on the Horizon!
BE PREPARED FOR AWESOMENESS!“The principles of physics, as far as I can see, do not speak against the possibility of maneuvering things atom by atom.”
~Richard Feynman
“It is something, in principle, that can be done, but in practice, it has not been done because we are too big.”
~Richard Feynman
Grand Challenge- Engineering Better Medicines
• Personalized• Monitors individual needs• Not generalized• Prevents some major diabetes’ problems
Journey Through a Vein
• Inserted in thigh• Travels through vein• Lodges in capillary bed in spleen• Detects oxygen• Begins detecting fatty acids
And Down to the Stomach…
• Hops on artery• Travels to stomach and surrounding area• Deposits fatty acid• Travels back to spleen
Production Phases
• Supplier: RAK Ceramics for tile and Biophan for actual nanobot
• Manufacturer: Biophan• Distributor: Hospitals • No wholesaler or retailer• Consumer: Patient
“My own judgment is that the nanotechnology revolution has the potential to change America on a scale equal to, if not greater than, the computer revolution.”
~ U.S. Senator Ron Wyden
Works Cited• Hagberg CE (2012 Oct 18). Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes. Retrieved from
http://www.ncbl.nlm.nih.gov/m/pubmed/23023133/.• KidsHealth. (2010, August). When Blood Sugar is Too High. “KidsHealth”.org. Retrieved March 19, 2013, from
m.kidshealth.org/teen/diabetes_c/basics/high_blood_sugar.html• What is nanotechnology. (n.d.). Retrieved from www.crnano.org/whatis.htm• Size of the nanoscale. (n.d.). Retrieved from http://www.nano.gov/nanotech-101/what/nano-size• Where is nanotechnology used. (n.d.). Retrieved from http://www.which.co.uk/campaigns/technology/what-you-need-to-know-
about-nanotechnology/where-is-nanotechnology-used/• Nanotechnology basics: for students and other learners. (n.d.). Retrieved from www.crnano.org/basics.htm• Hochella, M. (2007, June 14). How do we "see" and study nanoparticles in the clark fork river. Retrieved from Pulseplanet.com/sci-
diaries/sd_hochella/how-do-we-see-and-study-nanoparticles-in-the-clark-fork-river/• Nanotechnology: dangers of molecular manufacturing. (n.d.). Retrieved from www.crnano.org/dangers.htm• Nanotechnology: benefits of molecular manufacturing. (n.d.). Retrieved from www.crnano.org/benefits.htm• Maher. E. (2012, October 3). Blue light effected technology Backgrounds. PPT-Backgrounds. Retrieved April 25, 2013, from http://
www.ppt-backgrounds.net/powerpoint/878-blue-light-effected-technology-backgrounds.• Maher. E. (2012, October 1). Modern Tech Effect Presentation Backgrounds. PPT-Backgrounds. Retrieved April 25, 2013, from
http://www.ppt-backgrounds.net/technology/819-modern-tech-effect-presentation-backgrounds.• Rak Ceramics retains No.1 ranking as the world’s largest ceramic tile manufacturer. RAK Ceramics. Retrieved May 1, 2013, from
www.rakceramics.com/pressrelease65.php# • Company Overview. Biophan Technologies, Inc. Retrieved May 1, 2013, from
www.biophan.com/index.php?option=com_content&task=view&id=31&Itemid=212 • Diabetes Myths. American Diabetes Association. Retrieved May 6, 2013, from
www.diabetes.org/diabetes-basics/diabetes-myths/?loc=DropDownDB-mywths • Ledbetter, C. (2013, September). Biomolecules.