1. Reliance for Asthma Patients The Bridge Between Chronic & Primary Care ProductPresented By: Md.Mahbubur RahmanBrand Executive Asiatic Laboratories Ltd. Cell: 01937990051

2. Pharma Market Therapeutic Class ims codeTherapeutic ClassMAT Val 09/2011 (Crore)Gr (%)AALIMENTARY T.& METABOLISM266428.53JSYSTEMIC ANTI-INFECTIVES180814.68NNERVOUS SYSTEM84229.25RRESPIRATORY SYSTEM64930.71CCARDIOVASCULAR SYSTEM65830.89MMUSCULO-SKELETAL SYSTEM42323.92DDERMATOLOGICALS17522.53BBLOOD + B.FORMING ORGANS17227.24GG.U.SYSTEM & SEX HORMONES18034.91KHOSPITAL SOLUTIONS13317.09PPARASITOLOGY10415.69SSENSORY ORGANS11419.86HSYSTEMIC HORMONES8919.14LANTINEOPLAST+IMMUNOMODUL2139.86Ref: IMS MAT 09/2011 3. Prevalence of Asthma in Bangladesh Major NCDs reported by principal investigators in Bangladesh are CVD, Cancer, DM, Injuries, Chronic Respiratory Disease5.According to WHO 85 Lacks Bangladesh2.patients are suffering from Asthma inAccording to 4P Approximately 6000 doctors of various speciality are prescrbing Montelukast in Bangladesh3.Ref: 5 Noncommunicable Diseases in South-East Asian Region. 2. A Profile. World Health Organization 2002. Independent, 11 July, 2012. 3. 4P 2012The 4. Understanding AsthmaAsthma Medical Animation_(360p).flv 5. What is Asthma ? Asthma is a chronic inflammation of the airways in your lungs, tiny pockets called alveoli where oxygen and carbon dioxide are exchanged as you breathe. An asthma attack occurs when the lung tissue is inflamed to such a point that enough oxygen cant enter the blood stream and carbon dioxide cant be expelled. 6. , , 7. , , - 8. , (allergen) , , , , , , ( ), , 9. Market Scenario of MONTELUKAST Therapeutic ClassTotal SalesTherapeutic Market (ANTILEUK ANTIASTHMATICS)103.37 Crore25.7165.10103.37 Crore100.0065.10Generic Market ( MONTELUKAST)Share %Growth %Ref: IMS MAT 1st QTR, 2012 10. Market Scenario of MONTELUKAST Top 6 Competitors Market Size SlBrand Name1MONTAIR2MONAS3PROVAIR4M-KAST5 6Total Sales Company Name (Crore) Share % Growth % Incepta21.4620.7660.44Acme16.6816.1412.36Unihealth12.7012.29331.87Drug Inter.11.6311.2555.36MONTENESquare0.626.0651.71LUMONAESK+F0.494.79146.79Ref: IMS MAT 1st QTR, 2012 11. Drugs Used As Anti-astmatic Sl.Sub Therapeutic ClassGeneric1Beta Adrenergic AgonistsSalbutamol, Levo- Salbutamol, Salmeterol2CorticosteroidsHydrocortisone, Betamethsone, Fluticasone3DimethylxanthineTheophylline, Aminophylline4Leukotrienes Receptor AntagonistMontelukast, Zafirlukast 12. Therapeutic Class of LiamAnti Asthmatic Montelukast is A Potent Leukotrienes Receptor Antagonist 13. What are Leukotrienes? Leukotrienes are a naturally occurring chemical substance (Autacoids) that promotes an inflammatory response. When produced and released in the body, this chemical causes airway constriction, the tightening of muscles, and excess mucus and fluid. 14. Effect of Leukotrienes in Respiratory Tract?leuko_asthma_interactive - Liam.ppt 15. When Leukotrienes are Released?If anyone breathe an asthma triggers ,the body of asthmatics person release Leukotrienes. 16. Mechanism of Action of Liam Phospholipids Arachidonic acid5lipooxygene aseCOX Leukotrienes LeukotrienesPG Thromboxanes Liam Liam *Bronchodiletor *Anti-inflammatory Properties AsthmaBinds with Leukotriene Receptor1.Causes bronchoconstriction 2.Increases mucus secretion 3.Increases Vascular permeability 4.Causes edema 17. Disease BriefPersistent asthma Allergic rhinitis 18. Disease BriefExercise-induced asthmaAspirin/ NSAID sensitive asthma 19. Disease BriefAllergen-induced asthmaAs add on therapy with inhaled corticosteroids 20. IntroducesLiam 10 : Each tablet contains Montelukast Sodium INN equivalent to 10 mg Montelukast. Pack Size: 1X10s. MRP: TK. 15/Tablet, TP+VAT: 13.19/ Tablet 21. Dosage Guidelines of Liam Tablet Dose : 10 mg once daily at evening Duration of Dose : Since the patients with asthma need to take medicine to control the disease for longer period, Liam can be used for long term as per physician advice 22. Pregnancy category : B 23. Why Montelukast should be taken at night? As its major side effect is fatigue. Its much to easier to deal at night when youre about to go to bed anyway, rather than trying to battle it during the day. 24. Target Doctors of Liam Tablet Speciality Wise:1. Chest Specialist 2. Medicine Specialist 3. ENT Specialist 4. Skin & VD Specialist 5. Cardiologist 6. GP 7. Hospital Doctors 8. Doctor Cum Chemist 9. RMP 25. Liam Visual Aid (Page 1) 26. Liam Visual Aid (Page 2) 27. Liam Visual Aid (Page 3) 28. Liam Visual Aid (Page 4) 29. Liam Show Card (Page 1) 30. Liam Show Card (Page 2) 31. Liam Leave Piece (Page 1 & 2) 32. Liam Leave Piece (Page 3 & 4) 33. Benefits of Liam Tablet An oral medication and may be much easier for you to take. Liam Tablet ensures : Decrease bronchoconstriction Decrease mucus production Decrease inflammation Reduce allergic rhinitis Reduce nasal polyps 34. Benefits of Liam Tablet In clinical studies, Liam Tablet (monteleukast) ensures Improved asthma control during a 12-week treatment period Provide clinical benefit when added to an inhaled steroid Have allowed for a lower dose of an inhaled steroid Decrease nocturnal asthma symptoms Improved quality of life 35. SWOT Analysis of Liam Strength 1. Strong Marketing Team 2. Our strength and penetration in Periphery Market. 3. High concentration of Entire Management on this value earning product. 4. Growth and dynamism of this generic.Weakness 1. Low specialist doctor coverage. 2. Lack of proper training 3. Low institution & potential area coverage like Dhaka.Opportunity 1. Positive market growth of this generic. 2. There is a vast scope to penetrate into the rural area 3. Generic have unique advantage over other oral anti asthmatic therapyThreat 1. Competitors are very active in the market. 2. We are very new in this therapeutic market 3. Number of competitors is increasing day by dayKey facts: 1. Low specialist doctor coverage. 2. Lack of proper training Strategic goal: Increased specialist doctor coverage & arrange CME with these doctors Arrange good training program in every depot during monthly meeting about this product. 36. What is our Target ? How to achieve the forecast: Total MPO: Target Dr. Per MPO: Total Doctor No. of Visit Per Dr./Month No. of Prescription/Week/MPO No. of Total Prescription/Week 10 mg Sales (Box)/Week/MPO 10 mg Sales (Box)/Month/MPO Total 10 mg (Box)/Sales/Month500 3 1500 5 7 3500 7 28 140007 Prescription / Week/ Doctor. 37. Thank You !