Lesson 2.1.2

Avery

The Insulin Glucose ConnectionIntroduction:

● The building blocks for our body are cells● Cells are able to communicate by different molecules that move from cell to cell● The molecules that are used are called proteins● The protein is released from one cell and sent to another cell. They attach at

receptors

Goals of the Lesson1. To differentiate between a credible/non-credible source2. Use the internet to research the connection between Insulin and Glucose.3. Write a summary on the process of insulin binding to the cell to accept glucose 4. Using credible sources research key terms and their connection5. Research similarities and differences between Type 1 and 2 with regards to how

the body uses insulin6. Create a 3D model that represents how the body gets glucose into the cell with

type one and type two diabetes.

Credible SourcesTo tell if a website is credible or not use the following chart to check.

Credible Not Credible

Author Establishes credibility on the topic (degrees, experience)

No information on the author

Website/Url A credible website (gov site, university, charity)

People can change the information and give false info (Wiki)

Ad’s Little to no pop ups or ads A lot of pop-ups and ads

Date Has a recent or newer copyright date

Old/out of date,old information

Reference Has references and additional links

No references

Summary of Insulin and Glucose

1. The digestive system breaks down food that was eaten to simple glucose molecules 2. Glucose enters the bloodstream and flows through the pancreas3. The pancreas releases insulin into the bloodstream4. The glucose arrives at the cell but can’t get into the cell without the insulin5. The insulin arrives and attaches itself to the insulin receptor on the outside of the

cell membrane6. The insulin receptor triggers glut4 transporters to travel to the inside of the cell

membrane to open up part of the cell membrane for the glucose to come in 7. Cell can use glucose to make energy

Key Terms ● Insulin: Hormone produced in the pancreas that is used by the body to let glucose

into the cell● Glucose: Sugar that is found in food that the is used by the cells as a form of

energy● Beta Cells: Specialized cells in the pancreas that release insulin as blood glucose

levels increase● Glut 4 Transporters: Transport protein inside a cell that is triggered by the insulin

receptor to attach to the cell membrane and open it up to for the glucose● Insulin Receptor: A receptor that sits on the outside of the membrane and is the

place where insulin attaches to release glut4 ● Blood: In reference to diabetes the blood carries glucose and insulin to different

cells and different parts in the body.● Lymph: The lymph in the body can attack insulin causing the body to not get

enough glucose into the cells● Cell Membrane: Outer layer of the cell that is semi-permeable and regulates what

comes in and goes out of the cell

Similarities Between Type 1&2

Type 1 Similarities Type 2

Is detected in youth Have similar symptoms Detected in later years

Body doesn’t produce insulin

Failure to produce proper insulin

Produces insulin that gets rejected by the cells

Insulin injections are used as a mediation

Insulin is a treatment Can be regulated with healthy exercise and diet

3D ModelLast part of the lesson was to create a 3D moveable model that shows how a person with diabetes’ body’s relationship between insulin and glucose.

1. The model needs to be simple and easy enough to understand, like you were going to give a presentation to people who were recently diagnosed with type 1 or 2 diabetes.

2. The presentation must have included all of the key terms and how the work within the body.

3. It must be easy to understand for people who have no prior knowledge on the disease.