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Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone, Andrew M. Allen, Jaspreet Bassi, Joel K. Elmquist, Julia M. Keogh, Elana Henning, Martin G. Myers, Julio Licinio, Russell D. Brown, Pablo J. Enriori, Stephen O’Rahilly, Scott M. Sternson, Kevin L. Grove, David C. Spanswick, I. Sadaf Farooqi, Michael A. Cowley Cell Volume 159, Issue 6, Pages 1404-1416 (December 2014) DOI: 10.1016/j.cell.2014.10.058 Copyright © 2014 The Authors Terms and Conditions

Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

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Page 1: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Leptin Mediates the Increase in Blood Pressure Associated with Obesity 

Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone, Andrew M. Allen, Jaspreet Bassi, Joel K. Elmquist, Julia M. Keogh, Elana Henning, Martin G. Myers, Julio Licinio, Russell D. Brown, Pablo J. Enriori, Stephen O’Rahilly, Scott M.

Sternson, Kevin L. Grove, David C. Spanswick, I. Sadaf Farooqi, Michael A. Cowley 

Cell Volume 159, Issue 6, Pages 1404-1416 (December 2014)

DOI: 10.1016/j.cell.2014.10.058

Copyright © 2014 The Authors Terms and Conditions

Page 2: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure 1

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 3: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure 2

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 4: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure 3

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 5: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure 4

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 6: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure 5

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 7: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure 6

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 8: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure S1

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 9: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure S2

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 10: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure S3

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 11: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure S4

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 12: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Figure S5

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions

Page 13: Leptin Mediates the Increase in Blood Pressure Associated with Obesity Stephanie E. Simonds, Jack T. Pryor, Eric Ravussin, Frank L. Greenway, Ralph Dileone,

Cell 2014 159, 1404-1416DOI: (10.1016/j.cell.2014.10.058) Copyright © 2014 The Authors Terms and Conditions