Lenses and Magnification

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    Lenses and Magnification

    Ocular Prosthesis |

    Group 3

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    MICROPTHALMIA also referred to as microphthalmos, nanophthalmia

    or nanophthalmos, is a developmental disorder of

    the eye that literally means small eye (micros = small;

    ophthalmos = eye).

    One (Unilateral Microphthalmia) or both (Bilateral

    Microphthalmia) eyes may be involved.

    grossly visible, but small malformed globe

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    Causes

    Idiopathic/sporadic

    Inherited as dominant, recessive, or sex-linked

    Chromosome deletion in band

    Maternal infections or teratogenic exposure

    75% associated with syndromes

    Microphthalmia in newborns is sometimes associated with

    fetal alcohol syndrome or infections during pregnancy,

    particularly herpes simplex virus, rubella and cytomegalvirus

    (CMV), but the evidence is inconclusive.

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    Pathophysiology

    Development problem with optic disc in week 4 or

    later

    Morbidity Outgrowth of the globe drives growth and

    development of the bony orbit .

    Prevents fitting of prosthesis

    Unilateral anophthalmos hemifacial hypoplasia

    Bilateral anophthalmos central hypoplasia

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    Rare Condition S

    panishS

    tudy of 1.1 million births: 36/100,000 with eye malformations

    23/100,000 with

    anophthalmia/microphthalmia

    No racial predilection |No sex predilection

    Microphthalmia and Coloboma occur in around

    1 in 10,000 births.

    Clusters of anophthalmia and microphthalmiain England have been alleged in the media,

    with hypothesized links to environmental

    exposure such as pesticides

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    Associated Ocular Findings

    Orbital findings Small orbital rim and entrance

    Reduced size of bony orbital cavity

    Extraocular muscles usually absent

    Lacrimal gland may be absent Small and maldeveloped optic foramen

    Eyelid findings Foreshortening of the lids in all directions

    Absent or decreased levator function with decreased lidfolds

    Contraction of orbicularis oculi muscle

    Shallow conjunctival fornix, especially inferiorly

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    3D CT Reconstruction

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    Treatment Options

    Progressive conformers i.e. artificial eyes or contact lenses

    Easily extruded

    Balloon expanders i.e. skin flaps/ grafts for tissue skin

    expansion

    Easily extruded and require cooperation

    Progressive orbital implants

    Require multiple surgeries

    Hydrogel tissue expander implant (self-inflating)

    Good early results

    Late complications in scleral buckling

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    Procedure

    Children can be fitted for a prosthetic(artificial) eye for cosmetic purposes and to

    promote socket growth.

    Every few weeks a child will progress to alarger size conformer until about two years of

    age.

    The average child will need three to four newpainted prostheses before the age of 10.

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    The specialist in prosthetic diseases for the eye will

    make conformers, plastic structures that helpsupport the face and encourage the eye socket to

    grow.

    Children with microphthalmia may have some

    residual vision (limited sight). In these cases, thegood eye can be patched to strengthen vision in the

    microphthalmic eye. A prosthesis can be made to cap

    the microphthalmic eye to help with cosmetic

    appearance, while preserving the remaining sight.

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    Complications

    Significant cosmetic deformities if not

    treated early

    Fitted prostheses are completelyimmobile.

    Shortened and immobile eyelids

    Even with treatment, results often arecosmetically disappointing.

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    Patient Education

    Treatment will be long and complicated

    Multiple surgical treatments throughout

    a patients lifetime

    Consider genetic counseling in familial

    cases

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    The Formation of Images by Lenses

    IMAGE FORMATION BYA CONVERGING LENS

    In this example, when the object is placed further than

    twice the focal length from the lens, the real image isinverted and smaller than the object.

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    A diverging lens always forms an upright, virtual, diminished image.

    The Formation of Images by Lenses

    IMAGE FORMATION BYA DIVERGING LENS

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    Angular Magnification.

    d1

    h1 NE U

    h5U

    Optical Device

    e.g. Telescope

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    Angular Magnification

    M = angle subtended at the eye by instrument imageangle subtended at the eye by object

    This is generally refers to the magnification provided

    by optical instruments (e.g. telescopes).

    Versatile means of magnification as it does not involve

    changing object or viewing distance.

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    d1

    h4

    NEU

    U h4

    Real Image or Transverse Magnification

    h1

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    Real Image or Transverse Magnification

    M = tan U = h4

    x d1 =

    h4

    U d1 x h1 h1

    M = size of real image

    size of object

    This is typical of the situation used with a CCTV device

    where a magnified image of the object is created on a

    TV screen.

    This real image is created in approximately the samelocation as the object.

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    Magnification is NOT aboutmaking objects clearer it is

    simply about making them

    bigger.

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    Type of

    Magnification

    Field of

    View

    Working

    Space

    Distance of

    Task

    Increase size

    Decrease distance

    (by +ve lens magnifiers)

    Real image

    Angular

    (Telescope)

    No change

    No change

    Decreased

    Decreased

    Decreased

    No change

    Decreased

    Decreased

    No change

    No change

    Usually N only

    D, I or N

    Near only

    Usually N only

    D, I or N

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    Thank you!