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Lenses and Magnification
Ocular Prosthesis |
Group 3
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MICROPTHALMIA also referred to as microphthalmos, nanophthalmia
or nanophthalmos, is a developmental disorder of
the eye that literally means small eye (micros = small;
ophthalmos = eye).
One (Unilateral Microphthalmia) or both (Bilateral
Microphthalmia) eyes may be involved.
grossly visible, but small malformed globe
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Causes
Idiopathic/sporadic
Inherited as dominant, recessive, or sex-linked
Chromosome deletion in band
Maternal infections or teratogenic exposure
75% associated with syndromes
Microphthalmia in newborns is sometimes associated with
fetal alcohol syndrome or infections during pregnancy,
particularly herpes simplex virus, rubella and cytomegalvirus
(CMV), but the evidence is inconclusive.
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Pathophysiology
Development problem with optic disc in week 4 or
later
Morbidity Outgrowth of the globe drives growth and
development of the bony orbit .
Prevents fitting of prosthesis
Unilateral anophthalmos hemifacial hypoplasia
Bilateral anophthalmos central hypoplasia
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Rare Condition S
panishS
tudy of 1.1 million births: 36/100,000 with eye malformations
23/100,000 with
anophthalmia/microphthalmia
No racial predilection |No sex predilection
Microphthalmia and Coloboma occur in around
1 in 10,000 births.
Clusters of anophthalmia and microphthalmiain England have been alleged in the media,
with hypothesized links to environmental
exposure such as pesticides
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Associated Ocular Findings
Orbital findings Small orbital rim and entrance
Reduced size of bony orbital cavity
Extraocular muscles usually absent
Lacrimal gland may be absent Small and maldeveloped optic foramen
Eyelid findings Foreshortening of the lids in all directions
Absent or decreased levator function with decreased lidfolds
Contraction of orbicularis oculi muscle
Shallow conjunctival fornix, especially inferiorly
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3D CT Reconstruction
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Treatment Options
Progressive conformers i.e. artificial eyes or contact lenses
Easily extruded
Balloon expanders i.e. skin flaps/ grafts for tissue skin
expansion
Easily extruded and require cooperation
Progressive orbital implants
Require multiple surgeries
Hydrogel tissue expander implant (self-inflating)
Good early results
Late complications in scleral buckling
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Procedure
Children can be fitted for a prosthetic(artificial) eye for cosmetic purposes and to
promote socket growth.
Every few weeks a child will progress to alarger size conformer until about two years of
age.
The average child will need three to four newpainted prostheses before the age of 10.
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The specialist in prosthetic diseases for the eye will
make conformers, plastic structures that helpsupport the face and encourage the eye socket to
grow.
Children with microphthalmia may have some
residual vision (limited sight). In these cases, thegood eye can be patched to strengthen vision in the
microphthalmic eye. A prosthesis can be made to cap
the microphthalmic eye to help with cosmetic
appearance, while preserving the remaining sight.
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Complications
Significant cosmetic deformities if not
treated early
Fitted prostheses are completelyimmobile.
Shortened and immobile eyelids
Even with treatment, results often arecosmetically disappointing.
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Patient Education
Treatment will be long and complicated
Multiple surgical treatments throughout
a patients lifetime
Consider genetic counseling in familial
cases
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The Formation of Images by Lenses
IMAGE FORMATION BYA CONVERGING LENS
In this example, when the object is placed further than
twice the focal length from the lens, the real image isinverted and smaller than the object.
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A diverging lens always forms an upright, virtual, diminished image.
The Formation of Images by Lenses
IMAGE FORMATION BYA DIVERGING LENS
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Angular Magnification.
d1
h1 NE U
h5U
Optical Device
e.g. Telescope
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Angular Magnification
M = angle subtended at the eye by instrument imageangle subtended at the eye by object
This is generally refers to the magnification provided
by optical instruments (e.g. telescopes).
Versatile means of magnification as it does not involve
changing object or viewing distance.
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d1
h4
NEU
U h4
Real Image or Transverse Magnification
h1
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Real Image or Transverse Magnification
M = tan U = h4
x d1 =
h4
U d1 x h1 h1
M = size of real image
size of object
This is typical of the situation used with a CCTV device
where a magnified image of the object is created on a
TV screen.
This real image is created in approximately the samelocation as the object.
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Magnification is NOT aboutmaking objects clearer it is
simply about making them
bigger.
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Type of
Magnification
Field of
View
Working
Space
Distance of
Task
Increase size
Decrease distance
(by +ve lens magnifiers)
Real image
Angular
(Telescope)
No change
No change
Decreased
Decreased
Decreased
No change
Decreased
Decreased
No change
No change
Usually N only
D, I or N
Near only
Usually N only
D, I or N
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Thank you!