Lasting Ethical Implication in Research

Lasting Ethical Implication in Research: The Tuskegee ExperienceSapana PandayWidener University

1History of Bioethics Commissions1996-20011974781978-831994-95The Advisory Committee on Human Radiation ExperimentsThe National Commission for the Protection of Human Subjects of Biomedical Behavioral Research200109

2The Belmont ReportThe Belmont report is a statement of basic ethical principles and guidelines surrounding the conduct of research with human subjects.The report was published in the Federal Register, and reprints provided upon request. This was to ensure that it was readily available to scientists, members of Institutional Review Boards, and Federal employees.

ohsr.od.nih.gov/guidelines/belmont.html

3Boundaries between Practiceand ResearchThe distinction between practice and research is blurred especially when they occur together.Practice: interventions that are designed solely to enhance the well-being of an individual patient and that has a reasonable expectation of success. Research: an activity designed to test an hypothesis, with the potential to generate generalizable knowledge.

Practice and research may be carried on together when trying to evaluate the safety and efficacy of a therapy.ohsr.od.nih.gov/guidelines/belmont.html

4Basic Ethical Principles

ohsr.od.nih.gov/guidelines/belmont.html

5Applications

ohsr.od.nih.gov/guidelines/belmont.html

6Common Ruleori.hhs.gov/education/products/ucla/chapter2/page04b.htm

7it became the standard declaration of ethical principles for research not only in the United States, but in most of the rest of the world.Robert J . Levine, MDProfessor of MedicineYale UniversityCo-Author, Belmont Report

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