ORAL AND MAXILLOFACIAL PATHOLOGY OOOO

e126 Abstracts February 2014

SILVA, RICARDO ALVES MESQUITA. UNIVERSIDADEFEDERAL DE MINAS GERAIS.

Girl, 6, was referred to the School of Dentistry-UFMG forevaluation of “gingival inflammation” of 15 months’ duration plusprevious incisional biopsy with nonspecific result. There were nosystemic diseases. Extraoral and intraoral examinations revealedasymptomatic, bright red, multifocal patches in the gingiva nearteeth 12, 21, and 22. Laboratory evaluation was ordered. Thedifferential diagnosis included allergic reaction and gingivitisassociated with plaque. The patient was instructed in oral hygiene,and histopathological slides were evaluated. The final diagnosiswas juvenile spongiotic gingivitis. The patient was treated withchlorhexidine 0.12% three times a day and dental cream withoutsodium lauryl sulfate. After 14 days there was total clinicalregression of lesions near tooth 12 and partial clinical regression ofthe lesions near teeth 21 and 22. The patient is asymptomatic andbeing followed up in our service (CNPq/FAPEMIG).

AO-28 - KERATOACANTOMA OF LOWER LIP PRE-SENTED AS GIANT CUTANEOUS HORN. MARINACURRA, MANOELA DOMINGUES MARTINS, MANOELSANT’ANA FILHO, LAURA CAMPOS HILDEBRAND,MARCO ANTONIO TREVIZANI MARTINS, VINICIUSCOELHO CARRARD, MARIA CRISTINA MUNERATO. UNI-VERSIDADE FEDERAL DO RIO GRANDE DO SUL.

Cutaneous horn (CH) is a conical hyperkatotic projection ofskin with remarkable cohesiveness of the keratotic material. Abroad range of lesions may be present with the clinical signs of CH,including malignant tumors. Man, 77, presented an asymptomaticlesion in the lower lip with the clinical characteristics of CH thatprogressed over the course of 1 year. Squamous cell carcinoma(SCC) was suspected, so an incisional biopsy was performed.Histopathological analysis revealed a keratoacantoma (KA), whichwas removed completely. At 1-year follow-up no recurrencewas found. CH rarely is accompanied by KA, but KA shows agreater degree of nuclear atypia than SCC, making it difficultto differentiate the two diseases. This case highlights the impor-tance of histopathological examination to rule out malignancy.

AO-29 - LANGERHANS CELL HISTIOCYTOSIS: CASEREPORT WITH CYTOGENETIC APPROACH. JÉSSICAANNE PEREIRA CORRÊA, LIONEY NOBRE CABRAL,TIAGO NOVAES PINHEIRO, ELIANA BRASIL ALVES,ANGELA MARIA FERNANDES DOS SANTOS. UNI-VERSIDADE DO ESTADO DO AMAZONAS.

Langerhans cell histiocytosis is a rare disease that usuallyaffects children, without gender predilection. Boy, 3, was referredto the Oral Medicine service with granulomatous and ulcerouslesions in the hard palate and alveolar gingiva, as well as swollenareas on the head. Specimens obtained through incisional biopsiesof the intraoral lesions underwent histopathological and immu-nohistochemical examination, yielding the diagnosis of Langer-hans cell histiocytosis. Furthermore, classical cytogenetic analysisrevealed karyotypic alteration 46,XY del(22)(q11.2). Treatmentconsisted of chemotherapy with the topoisomerase inhibitorEtoposide. At 1-year follow-up the patient evidenced a goodresponse to the treatment. Current clinical prognosis is favorable.

AO-30 - LEPROSY, PARACOCCIDIOIDOMYCOSIS,AND SQUAMOUS CELL CARCINOMA: DIAGNOSTICDISABILITY OR HEALTH SYSTEM FAILURE? MAYARABARBOSA VIANDELLI MUNDIM, ALEXANDRE BELLOTTI

FERREIRA, ELISMAURO FRANCISCO DE MENDONÇA,REJANE FARIA RIBEIRO-ROTTA. UNIVERSIDADE FED-ERAL DE GOIÁS.

Although public protocols have achieved widespread leprosyand paracoccidiodomycosis control, advanced cases can still bedetected. This case report presents a strong association betweenthese two infectious diseases and malignant neoplasms andprompts reflection on this apparent failure of the public healthsystem to monitor the progress of these endemic diseases. Man, 48,diagnosed with leprosy and paracoccidioidomycosis in 2002 wasseen at Centro Goiano de Doenças da Boca in 2011. He evidencedsessile and hypopigmented lesions in the perioral and nasal regionalong with nasal cartilage loss causing total obstruction of theupper airways. Histological examination of biopsy tissue revealedsquamous cell carcinoma associated with fungal lesions. The pa-tient was referred to a specialized oncology and infectious diseasesservice and died 6 months after starting treatment.

AO-31 - LEUKOPLAKIA LESION IN A PATIENT WITHHISTORY OF GRAFT-VERSUS-HOST DISEASE. CRISTINALIMA LEITE CARVALHAES, MARIA CAROLINA NUNESVILELA, KARIN SÁ FERNANDES, NELISE ALEXANDRELASCANE, PAULO SERGIO DA SILVA SANTOS, ANDRÉAMANTESSO, NATHALIE PEPE MEDEIROS DE REZENDE.FACULDADE DE ODONTOLOGIA DA UNIVERSIDADE DOESTADO DO SÃO PAULO.

Graft versus host disease (GVHD) is a complication related tobonemarrow transplantation (BMT) that is characterized by immunereaction of graft donor immunocompetent cells to an immunocom-promised host. Oral mucosa lesions are characterized by lichenoidlesions, ulceration, and xerostomia. Man, 41, a non-smoker non-alcoholic, had amedical history of marrow aplasia followed byBMTwith complications, including acute GVHD of the oral mucosa, lip,and liver that was treated with systemic/local corticosteroids. He wascurrently taking antihypertensive drugs. In 2009, 2-mm leukoplasticpainless lesions appeared on the palate. They were monitored until2013, when they increased in size and changed clinical characteris-tics, becoming diffusewith irregular borders, alternating leukoplakia,erythroplakia, and ulcerated areas, and a rough surface. Two inci-sional biopsies were performed, yielding a diagnosis of hyperkera-tosis and acanthosis with mild dysplasia. Dysplastic lesions in BMTpatients with GVHD should bemonitored because of the high risk ofdeveloping a new malignancy.

AO-32 - MALT LYMPHOMA: CLINICAL CASEREPORT. JAMILLE RIOS MOURA, MÁRCIO CAMPOSOLIVEIRA, JEAN NUNES DOS SANTOS, MICHELLEMIRANDA LOPES FALCÃO, TARSILA DE CARVALHOFREITAS RAMOS, BRUNO CUNHA PIRES, VALÉRIA SOUZAFREITAS. UNIVERSIDADE ESTADUAL DE FEIRA DESANTANA.

Mucosa-associated lymphoid tissue (MALT) lymphoma is atype of non-Hodgkin’s lymphoma that can affect the salivaryglands. Woman, 41, was seen at the State University of Feira deSantana complaining about “swelling below the tongue” thatprogressed over the course of 8 months. Intraoral clinical exam-ination showed a raised lesion on the left side of the floor of themouth that measured about 7 cm, had a soft surface, and was wellcircumscribed. After biopsy, histopathological analysis led to adiagnosis of atypical lymphoid proliferation. The result of immu-nohistochemical analysis supported a diagnosis compatible withMALT lymphoma. The clinical and morphological features and