L1_structural Organization of the Human Body

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    PP121 Introductory Physiologyby Dr Lee Siew KeahFaculty of Pharmaceutical SciencesUCSI University

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    To identify the hierarchy of the structuralorganization

    To identify major organ systems of the body andtheir major componentsTo describe the basic functions of human bodyTo identify the anatomical terms & major bodycavities

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    Anatomy the study of the structure of the bodyand the relationships of the various parts of the body

    Gross/macroscopic

    Microscopic i.e cytology (cellular), histology (tissue)Developmental structural changes

    Physiology the study of the functions of the partsof the body, includes specific organ systems ,molecular and cellular levels e.g renal physiology,neurophysiology, cardiovascular physiology

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    Name Definition Example

    Chemical Interactions between atoms and

    their combinations intomolecules

    Atoms: H and O

    Molecule: H 2O

    Organelles Microscopic structures in thecell; composed of molecules thatare specialized to carry outfunctions of the cell

    Mitochondria, ribosome,lysosome.

    Cells Basic units of living organism Skin cells, nerve cells,and RBC.

    Tissues A group of cells with similarstructure and function

    Epithelial, connectiveand muscle tissue.

    Organs Compose of two or more tissuestypes; organs perform one ormore common functions

    Heart, brain andstomach.

    Organ systems Groups of organs with a uniquecollective function

    Skeletal system, nervoussystem and digestivesystem.

    Organism A single complete individual 4

    Table: Hierarchy of structural organization

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    Atom

    Cell

    Macromolecule

    Molecule

    Organ

    Organ system

    Organelle

    Organism

    Tissue

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    Necessary Life FunctionsResponsiveness & adaptability

    Growth & ReproductionMovementRespirationCirculation

    DigestionExcretion

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    Survival needsNutrients

    WaterOxygen Appropriate temperature Appropriate atmospheric

    pressure

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    1. Integumentary2. Muscular system

    3. Skeletal system4. Nervous system5. Endocrine system6. Cardiovascular system

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    7. Respiratory system8. Lymphatic & immune system9. Digestive system10. Urinary system11. Reproductive system

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    Major organs/tissues:Skin, hair, nails

    Primary functions:Protects body from injury &dehydrationDefense against foreigninvaders

    Synthesis vitamin DRegulates body temperatureSensory detection

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    Major organs/tissues:BonesCartilage

    Bones marrow Associated ligaments

    Primary functions:Protects & support body organsProvides a framework formusclesBones - produce blood cellsBones - Store minerals

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    Major organs/tissues:Skeletal muscles, tendons

    Primary functions:Body movement/locomotionFacial expressionMaintains postureProduces heat & maintain bodytemperature

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    Major organs/tissues:BrainSpinal cord

    Peripheral nerves & gangliaSpecial sense organs

    Primary functions:Direct immediate response to stimuliCoordinates activities of organsystemsProvides and interpretssensory information

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    Major organs/tissues:All glands secretinghormones : pancreas, testes,ovary, pituitary, thyroid,parathyroid, adrenal,intestinal, thymus, heart,pineal

    Primary functions:Regulate processes likegrowth, reproduction,metabolismDirect long-term changes inthe activities of other organsystems

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    Major organs/tissues:Heart, blood vessels, blood

    Primary functions:Transport of blood throughoutthe bodys tissues Distributes heats and assist

    in body temperatureregulation

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    Major organs/tissues:WBC, lymph vessels &nodes, spleen, thymus,tonsils

    Primary functions:Defense against foreigninvadersReturn of extracellular fluid tobloodFormation of lymphocytes

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    Major organs/tissues:Nose, pharynx, larynx,trachea, bronchi, lungs

    Primary functions:Exchange of CO 2 and O 2Regulates acid-base balance

    Voice production

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    Major organs/tissues:Mouth, pharynx, esophagus,stomach, intestines, salivaryglands, pancreas, liver,gallbladder

    Primary functions:

    Digests food Absorbs water and nutrients

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    Major organs/tissues:Kidneys, ureter, bladder,urethra

    Primary functions:Regulate plasma compositionthrough controlled excretionof salts, water and organicwastesRegulates electrolyte, water,acid-base balance of the body

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    Major organs/tissues:Testes, penis, prostate gland,epididymis, ductus deferens,seminal vesicles, scrotum

    Primary functions:Produces sperms and

    produce male sex hormonesDeliver sperms to the femalereproductive tract

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    Major organs/tissues:Ovaries, uterine tubes, uterus,vagina, mammary glands

    Primary functions:Production of eggsProvision of a nutritiveenvironment for thedeveloping embryo and fetusNutrition to the infant

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    The study of the function of the humanbody is termed: __________.

    a. gross anatomyb. systemic anatomyc. cytologyd. physiology

    Marking Scheme

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    A group of similar cells that perform thesame function is classified as a(n)

    _______.

    a. tissueb. organc. organ systemd. organism

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    Identify the hierarchy of the structuralorganizationDescribe the basic functions of human bodyIdentify major organ systems of the body andtheir major componentsIdentify the anatomical terms & major bodycavities

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    Standard anatomical bodyposition

    Facing the observerStanding erect with feet slightlyapart

    Arms at the sides with palmsfacing forward

    Always use directional terms asif body is in anatomical position

    Right and left refer to bodybeing viewed, not those ofobserver

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    Two fundamental divisions Axial main axis of the body i.e head, neck and

    trunk Appendicular limbs

    Regional terms used to designate specific areas

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    Figure Regional terms used to designate specific body areas.

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    Cephalic

    OrbitalFrontal

    Nasal

    MentalOral

    Cervical

    ThoracicSternalAxillaryMammary

    AbdominalUmbilical

    PelvicInguinal

    (groin)

    Pubic (genital)

    Hallux

    DigitalMetatarsal

    Tarsal (ankle)Pedal (foot)

    Fibular or peroneal

    Crural (leg)

    PatellarFemoral (thigh)Coxal (hip)

    Lower limb

    DigitalPalmar

    PollexManus (hand)

    Carpal (wrist)(forearm)Antebrachial

    Brachial (arm)Acromial

    Upper limb

    Antecubital

    Anterior/Ventral

    ThoraxAbdomenBack (Dorsum)

    g g g p y

    Figure Regional terms used to designate specific body areas.

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    Plantar

    Calcaneal

    Pedal (foot)

    Fibular or peronealSural (calf)

    Femoral (thigh)

    Lower limb

    Digital

    Metacarpal

    Manus (hand)

    (forearm)AntebrachialOlecranal

    Brachial (arm)Acromial

    Upper limb

    Popliteal

    Perineal (betweenanus and externalgenitalia)

    Gluteal

    Sacral

    Lumbar

    Vertebral

    Scapular

    Cervical

    Back (dorsal)

    CephalicOticOccipital (backof head)

    Back (Dorsum)

    Posterior/Dorsal

    g g g p y

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    Body plane Flat surface along which body or structure may becut for anatomical study

    Sections Cuts or sections made along a body plane

    A cut along a sagittal plane produces a sagittal

    section

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    Three most commonSagittal planeFrontal (coronal) planeTransverse (horizontal) plane

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    Sagittal planeDivides body vertically into right and left partsProduces a sagittal section if cut along this planeMidsagittal (median) plane

    Lies on midline

    Parasagittal plane

    Offset from the midline

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    Frontal (coronal) plane

    Divides body vertically into anterior andposterior partsProduces a frontal or coronal section

    Transverse (horizontal) planeDivides body horizontally (90 to verticalplane) into superior and inferior partsProduces a cross section

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    Frontal plane

    Frontal section(through torso)

    Transverse section(through torso,inferior view)

    Median section(midsagittal)

    Transverse plane

    Median (midsagittal) plane

    IntestinesRectum

    Vertebral column

    Spleen

    Pancreas

    Body wall

    Aorta

    Spinal cordSubcutaneous fat layer

    Liver

    Arm

    StomachHeartLiverLeft and

    right lungs

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    Two sets of internal body cavities closed toenvironment

    Dorsal body cavityVentral body cavity

    Protect internal organs and cushion them fromshocks that occur during activity

    Allow organs within them to change size andshape without disrupting the activities of nearbyorgans

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    Protects nervous systemTwo subdivisions:

    Cranial cavity Encases brainVertebral cavity

    Encases spinal cord

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    Cranial cavity (contains brain)

    Vertebral cavity (contains spinalcord)

    Dorsalbody

    cavity

    Thoraciccavity (contains

    heart andlungs)

    Cranial

    cavity

    Vertebralcavity

    Superiormediastinum

    Pleuralcavity

    Pericardialcavity withinthe mediastinum

    Diaphragm

    Pelvic cavity (contains urinarybladder, reproductiveorgans, and rectum)

    Lateral view

    Abdomino-pelviccavity

    Abdominal cavity (contains digestiveviscera)

    Anterior view

    Ventral bodycavity (thoracic andabdominopelviccavities)

    Dorsal body cavity

    Ventral body cavity

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    Houses internal organs ( viscera )Two subdivisions (separated by diaphragm)

    Thoracic cavity Abdominopelvic cavity

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    Thoracic cavity subdivisionsSurrounded by the ribs and muscles of the chest

    Two pleural cavitiesEach houses a lung

    MediastinumContains pericardial cavity; encloses heart

    Surrounds thoracic organs e.g esophagus, trachea

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    Abdominopelvic cavity subdivisions Abdominal cavity

    Contains stomach, intestines, spleen, and liver

    Pelvic cavityContains urinary bladder, reproductive organs, andrectum

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    Cranial cavity (contains brain)

    Vertebral cavity (contains spinalcord)

    Dorsalbodycavity

    Thoraciccavity (contains

    heart andlungs)

    Cranial

    cavity

    Vertebralcavity

    Superiormediastinum

    Pleuralcavity

    Pericardialcavity withinthe mediastinum

    Diaphragm

    Pelvic cavity (contains urinarybladder, reproductiveorgans, and rectum)

    Lateral view

    Abdomino-pelviccavity

    Abdominal cavity (contains digestiveviscera)

    Anterior view

    Ventralbodycavity (thoracicandabdomino-

    pelviccavities)Dorsal body cavityVentral body cavity

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    Serous membrane or serosa Thin, double-layered membranes

    Parietal serosa lines internal body cavity wallsVisceral serosa covers internal organs (viscera)

    Layers separated by slit-like cavity filled withserous fluid

    Fluid secreted by both layers of membrane Allows the organs to slide without friction actoss thecavity walls, and as they carry out routine functions

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    Outer balloon wall(comparable to parietal serosa)

    Air (comparable to serous cavity)

    Inner balloon wall(comparable to visceral serosa)

    A fist thrust into a flaccid balloon demonstratesthe relationship between the parietal and visceralserous membrane layers.

    Heart

    Parietalpericardium

    Pericardialspace withserous fluid

    Visceralpericardium

    The serosae associated with the heart.

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    Named for specific cavity and organs with whichassociatedEach has parietal and visceral layersPericardium

    HeartPleurae

    LungsPeritoneum Abdominopelvic cavity

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    Visceralperitoneum

    Parietalperitoneum

    Parietalpericardium

    Visceralpericardium

    Visceralpleura

    Parietalpleura

    Serous membranes line body cavities that areclosed to the exterior.

    Serous membranes

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    Divisions used primarily by medical personnel

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    Right upperquadrant(RUQ)

    Right lowerquadrant(RLQ)

    Left upperquadrant(LUQ)

    Left lowerquadrant(LLQ)

    Figure The four abdominopelvic quadrants.

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    Righthypochondriac

    region

    Epigastricregion

    Rightlumbarregion

    Umbilicalregion

    Lefthypochondriac

    region

    Leftlumbarregion

    Right iliac(inguinal)

    region

    Hypogastric(public)region

    Left iliac(inguinal)

    region

    Liver

    Gallbladder

    Ascending colon of

    large intestineSmall intestine

    Cecum

    Appendix

    Diaphragm

    Spleen

    Stomach

    Transverse colon

    of large intestineDescending colonof large intestine

    Initial part ofsigmoid colon

    Urinary bladder

    Nine regions delineated by four planes Anterior view of the nine regions showing the superficial organs

    Figure The nine abdominopelvic regions.

    Divisions used primarily by anatomists

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    Exposed to environmentOral and digestive cavitiesNasal cavityOrbital cavitiesMiddle ear cavities

    Not exposed to environmentSynovial cavities

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    Humans differ externally and internally90% of all structures present in body matchdescription in textbookNerve or blood vessel may be out of placeSmalls muscle may be missing

    Extreme variations inconsistent with life

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    UterusSmall intestine

    RectumSpinal cordHeart

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    Pelvic AbdominalPelvicDorsalThoracic/mediastinum/Pericardial

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    Construct a table that lists the 11 systems of thebody, names two organs of each system, anddescribes overall or major function of eachsystem.

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