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    Nasal CPAP

    Definition

    CPAP stands for "continuous positive airway pressure." CPAP is a treatment that delivers slightly

    pressurized air during the breathing cycle.

    This keeps the windpipe open during sleep and prevents episodes of blocked breathing in persons

    withobstructive sleep apneaand other breathing problems.

    It is sometimes called nasal continuous positive airflow pressure (nCPAP).

    Alternative Names

    Continuous positive airway pressure; CPAP; Bilevel positive airway pressure; BiPAP; Autotitrating

    positive airway pressure; APAP; nCPAP

    Information

    WHO SHOULD USE CPAP

    Continuous positive airflow pressure (CPAP) is the best treatment for most people with obstructive sleep

    apnea. It is safe and effective in patients of all ages, including children. If you only have mild sleep apnea

    and do not feel very sleepy during the day, you may not need to use it.

    After using CPAP regularly, many patients report the following:

    Better concentration and memory

    Feeling more alert and less sleepy during the day

    Improved sleep for the person's bed partner

    Improvements in work productivity

    Less anxiety and depression and a better mood

    Normal sleep patterns

    Improvement in heart and blood vessel problems, such as high blood pressure

    A similar machine, called BiPAP (bilevel positive airway pressure) is used as an alternative to CPAP. With

    this machine, the pressure changes while a person breathes in and out.

    These devices are useful for children and adults with collapsible airways, small lung volumes, or muscle

    weakness that makes it difficult to breathe, such asmuscular dystrophy.

    CPAP or BiPAP may also be used by people who have:

    Acuterespiratory failure

    Central sleep apnea

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    COPD

    Heart failure

    HOW CPAP WORKS

    CPAP works in the following way:

    The device is a machine weighing about 5 pounds that fits on a bedside table.

    A mask fits over the nose. A tube connects the mask to the CPAP device.

    The machine delivers a steady stream of air under slight pressure through this tube into the mask.

    CPAP will be started while you are in the sleep center for the night. Sometimes, it can be started on the

    same night you have yoursleep study.

    The doctor, nurse, or therapist will help choose the mask that fits you best. They will also help adjust the

    settings on the machine while you are asleep. The settings on the CPAP machine depend on the severity

    of your sleep apnea.

    If you are using the CPAP machine but your sleep apnea symptoms do not improve, the settings on the

    machine may need to be changed. Some patients can be taught to adjust the CPAP at home. Otherwise,

    you will need to make trips to the sleep center.

    CPAP works by steadily increasing pressure in your airway. Newer devices, called autotitrating positive

    airway pressure (APAP), can respond to changes in pressure in your airway as they occur. This may be

    more comfortable, and it also can help you avoid overnight stays and other trips to the hospital.

    GETTING USED TO THE DEVICE

    It can take time to become used to a CPAP device. The first few nights of CPAP therapy are often the

    hardest. Some patients may sleep less or not sleep well at the start of treatment.

    Patients who are having problems may tend not to use CPAP for the whole night, or even stop using the

    device. However, it is important to use the machine for the entire night or for as long as possible.

    Common complaints include:

    A feeling of being closed in (claustrophobia)

    Chest muscle discomfort, which usually goes away after awhile

    Eye irritation

    Irritation and sores over the bridge of the nose

    Nasal congestion and sore or dry mouth

    Noise that interferes with sleep (although most machines are quiet)

    Nosebleeds

    Upper respiratory infections

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    Many of these problems can be helped or prevented by the following methods:

    Ask your doctor or therapist about using a mask that is lightweight and cushioned. Some masks are used

    only around or inside the nostrils.

    Make sure the mask fits correctly. It should not be too tight or too loose, and it should not leak any air. Try nasal salt water sprays for a stuffed nose.

    Use a humidifier to help with dry skin or nasal passages.

    Keep your CPAP equipment clean.

    Place your CPAP machine underneath your bed.

    Your doctor or therapist can lower the pressure on the CPAP machine and then increase it again at a

    slow pace. Some new machines can automatically adjust to the pressure that is needed.

    References

    McArdle N, Singh B, Murphy M. Continuous positive airway pressure titration for obstructive sleepapnoea: automatic versus manual titration. Thorax. 2010;65:606-611.

    Tomfohr LM, Ancoli-Israel S, Loredo JS, Dimsdale JE. Effects of continuous positive airway pressure on

    fatigue and sleepiness in patients with obstructive sleep apnea: data from a randomized controlled

    trial. Sleep. 2011;34:121-126.

    Basner RC. Continuous positive airway pressure for obstructive sleep apnea. N Engl J Med.

    2007;356:1751-1758.

    Epstein LJ, Kristo D, Strollo PJ Jr., et al.; Obstructive Sleep Apnea Task Force of the American Academy

    of Sleep Medicine. Clinical guideline for the evaluation, management, and long-term care of obstructive

    sleep apnea in adults. J Clin Sleep Med. 2009;5:263-276.

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    Chronic obstructive pulmonary disease

    Definition

    Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it

    difficult to breathe.

    There are two main forms of COPD:

    Chronic bronchitis, which involves a long-term cough with mucus

    Emphysema, which involves destruction of the lungs over time

    Most people with COPD have a combination of both conditions.

    Alternative Names

    COPD; Chronic obstructive airways disease; Chronic obstructive lung disease; Chronic bronchitis;

    Emphysema; Bronchitis - chronic

    Causes

    Smoking is the leading cause of COPD. The more a person smokes, the more likely that person will

    develop COPD. However, some people smoke for years and never get COPD.

    In rare cases, nonsmokers who lack a protein called alpha-1 antitrypsin can develop emphysema.

    Other risk factors for COPD are:

    Exposure to certain gases or fumes in the workplace

    Exposure to heavy amounts of secondhand smoke and pollution

    Frequent use of cooking fire without proper ventilation

    Symptoms

    Cough, with or without mucus

    Fatigue

    Many respiratory infections

    Shortness of breath (dyspnea)that gets worse with mild activity

    Trouble catching one's breath

    Wheezing

    Because the symptoms of COPD develop slowly, some people may not know that they are sick.

    Exams and Tests

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    The best test for COPD is a lung function test called spirometry.This involves blowing out as hard as

    possible into a small machine that tests lung capacity. The results can be checked right away, and the

    test does not involve exercising, drawing blood, or exposure to radiation.

    Using a stethoscope to listen to the lungs can also be helpful. However, sometimes the lungs sound

    normal even when COPD is present.

    Pictures of the lungs (such as x-rays and CT scans) can be helpful, but sometimes look normal even

    when a person has COPD (especiallychest x-ray).

    Sometimes patients need to have a blood test (calledarterial blood gas)to measure the amounts of

    oxygen and carbon dioxide in the blood.

    Treatment

    There is no cure for COPD. However, there are many things you can do to relieve symptoms and keep

    the disease from getting worse.

    Persons with COPD MUST stop smoking. This is the best way to slow down the lung damage.

    Medications used to treat COPD include:

    Inhalers (bronchodilators) to open the airways, such as ipratropium (Atrovent), tiotropium (Spiriva),

    salmeterol (Serevent), formoterol (Foradil), or albuterol

    Inhaled steroids to reduce lung inflammation

    Anti-inflammatory medications such as montelukast (Singulair) and roflimulast are sometimes used

    In severe cases or during flare-ups, you may need to receive:

    Steroids by mouth or through a vein (intravenously)

    Bronchodilators through a nebulizer

    Oxygen therapy

    Assistance during breathing from a machine (through a mask, BiPAP, or endotracheal tube)

    Antibiotics are prescribed during symptom flare-ups, because infections can make COPD worse.

    You may need oxygen therapy at home if you have a low level of oxygen in your blood.

    Pulmonary rehabilitation does not cure the lung disease, but it can teach you to breathe in a different way

    so you can stay active. Exercise can help maintain muscle strength in the legs.

    Walk to build up strength.

    Ask the doctor or therapist how far to walk.

    Slowly increase how far you walk.

    Try not to talk when you walk if you get short of breath.

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    Use pursed lip breathing when breathing out (to empty your lungs before the next breath)

    Things you can do to make it easier for yourself around the home include:

    Avoiding very cold air

    Making sure no one smokes in your home Reducing air pollution by getting rid of fireplace smoke and other irritants

    Eat a healthy diet with fish, poultry, or lean meat, as well as fruits and vegetables. If it is hard to keep your

    weight up, talk to a doctor or dietitian about eating foods with more calories.

    Surgery may be used, but only a few patients benefit from these surgical treatments:

    Surgery to remove parts of the diseased lung can help other areas (not as diseased) work better in some

    patients with emphysema

    Lung transplant for severe cases

    Support GroupsPeople often can help ease the stress of illness by joining a support group in which members share

    common experiences and problems.

    See also:Lung disease - support group

    Outlook (Prognosis)

    COPD is a long-term (chronic) illness. The disease will get worse more quickly if you do not stop smoking.

    Patients with severe COPD will be short of breath with most activities and will be admitted to the hospital

    more often. These patients should talk with their doctor about breathing machines and end-of-life care.

    Possible Complications

    Irregular heartbeat (arrhythmia)

    Need for breathing machine and oxygen therapy

    Right-sided heart failure orcor pulmonale(heart swelling andheart failuredue to chronic lung disease)

    Pneumonia

    Pneumothorax

    Severe weight loss and malnutrition

    Thinning of the bones (osteoporosis)

    When to Contact a Medical Professional

    Go to the emergency room or call the local emergency number (such as 911) if you have a rapid increase

    inshortness of breath.

    Prevention

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    Not smoking prevents most COPD. Ask your doctor or health care provider about quit-smoking programs.

    Medicines are also available to help kick the smoking habit. The medicines are most effective if you are

    motivated to quit.

    References

    Hoogendoorn M, Feenstra TL, Hoogenveen RT, Rutten-van Mlken MP. Long-term effectiveness and

    cost-effectiveness of smoking cessation interventions in patients with COPD. Thorax. 2010;65(8):711-

    718.

    Agarwal R, Aggarwal AN, Gupta D, Jindal SK. Inhaled corticosteroids vs placebo for preventing COPD

    exacerbations: a systematic review and metaregression of randomized controlled trials. Chest. 2010;

    137(2):318-325.

    Shapiro SD, Reilly JJ Jr., Rennard SI. Chronic bronchitis and emphysema. In: Mason RJ, Broaddus VC,

    Martin TR, et al. Murray & Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa: Saunders

    Elsevier; 2010:chap 39.

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