John T. Groves

Hugh Stott Taylor Chair of Chemistry

231 New Frick Laboratory Department of Chemistry

Princeton University Princeton, New Jersey 08544

Tel (609) 258-3593 E-mail: jtgroves@princeton.edu

Web page: http://chemistry.princeton.edu/groves/ Professional Experience: 1988-1993 Chair, Department of Chemistry, Princeton University 1985- Professor of Chemistry, Princeton University 1982-1985 Director, Michigan Center for Catalysis and Surface Science 1979-1985 Professor of Chemistry, The University of Michigan 1976-1979 Associate Professor of Chemistry, The University of Michigan 1969-1976 Assistant Professor of Chemistry, The University of Michigan 1966-1969 National Institutes of Health Pre-doctoral Fellow, Columbia University 1965-1969 Columbia University Faculty Fellow Education: - Columbia University, Ph.D. 1969; Research with Prof. Ronald Breslow - Massachusetts Institute of Technology, B.S. 1965; Research with Prof. Frederick Greene Honors and Recognitions: - American Chemical Society Award in Inorganic Chemistry, 2015 - Rayson Huang Prize and Lectureship in Chemistry, University of Hong Kong, 2015 - National Academy of Sciences, 2012 – - Ira Remsen Award, American Chemical Society, 2010 - Hans Fischer Award in Porphyrin Chemistry, Hans Fischer Gesellschaft (Munich), 2010 - Keller Center Award for Innovation and Entrepreneurship, Princeton University, 2010 - Fellow of the Royal Society of Chemistry, 2009- - Frontiers in Biological Chemistry Award, Max Planck Institute, 2009 - Grand Prix, Maison de la Chimie (Paris) Laureate, for contributions to mankind and nature, 2008 - National Science Foundation Extension Award for Special Creativity, 2008-2011 - National Institute of General Medical Sciences, NIH, MERIT Award, 2007-2017 - Cady Distinguished Lecturer, University of Washington, 2007 - Distinguished Visiting Professor University of Hong Kong, 2003 - Distinguished Lecturer in Inorganic Chemistry, Northwestern University, 2000 - Abbott Distinguished Lecturer in Organic Chemistry, Colorado State University, 2000 - Alfred Bader Award in Bioorganic and Bioinorganic Chemistry, American Chemical Society, 1996 - Eli Lilly Distinguished Lecturer, Indiana University, 1997 - Bergmann Lectureship, Yale University, 1997 - Fellow, Japan Society for the Promotion of Science, 1987 and 1997 - Fellow, American Academy of Arts and Sciences, 1993- - Morris S. Kharasch Visiting Professor, University of Chicago, 1993 - Hugh Stott Taylor Chair of Chemistry, Princeton University, 1991- - A. C. Cope Scholar Award, American Chemical Society, 1991 - National Science Foundation Extension Award for Special Creativity, 1990-1992 - Nichols Distinguished Lecturer, 1989 - Fellow, American Association for the Advancement of Science, 1984 - Phi Lambda Upsilon Award for Teaching and Leadership, 1978 - L. P. Hammett Award for Outstanding Graduate Research, Columbia University, 1969

J. T. Groves, page 2 Professional Societies: - American Chemical Society - New York Academy of Sciences - American Association for the Advancement of Science - Sigma Xi - American Academy of Arts and Sciences - Phi Lambda Upsilon Professional Activities: - Member, Metallobiochemistry Study Section, National Institutes of Health, 1979-1983 - Selection Committee, National Science Foundation Workshops, 1984, 1985, 1989 - Contributing Author to the "Pimentel Committee" Report to Congress, 1985 - Board of Editors, Bioorganic Chemistry, 1983-present - International Advisory Board, Symposium on Homogeneous Catalysis, 1984- - US-USSR Joint Symposium and Workshop on Environmentally Related Catalysis, Moscow, 1985, US Organizer - National Advisory General Medical Sciences Council, ad hoc Consultant, 1986 - DOE Evaluation Committee - Lawrence Berkeley Laboratory, 1986 - International Advisory Committee, International Symposium on the Activation of Dioxygen and Homogeneous Catalytic Oxidations, 1988-98 - Editorial Board, Reaction Kinetics and Catalysis Letters, 1989-present - Visiting Committee, Vanderbilt University, Program in Toxicology, 1989-92 - Visiting Committee, Department of Chemistry, University of Chicago, 1990. - Visiting Committee, University of California, Irvine, Graduate Science Program, 1992. - American Chemical Society, Selection Committee for ---- Award, 1989-1992; 2010-2012. - Board of Editors, Bioorganic and Medicinal Chemistry, 1993-2005 - Board of Editors, Bioorganic and Medicinal Chemistry Letters, 1993-2005 - Board of Editors, Inorganic Chemistry, 1994-1997 - Chairman, Metals in Biology Gordon Research Conference, 1994 - Member, Physical Biochemistry Study Section, NIH, 1995 - Board of Editors, Journal of Biological Inorganic Chemistry, 1995-2000 - Board of Editors, Journal of Inorganic Biochemistry, 2006- - Co-chair, 10th International Symposium on Homogeneous Catalysis, Princeton University, 1996 - Member, Metallobiochemistry Study Section, NIH, 1999, 2002 - Member, Council of the Society for Biological Inorganic Chemistry, 1998-2002 - Chair, ACS Canvassing Committee for the Ronald Breslow Award, 2001-3 - Member, Special Study Section, NIH 2004, 2006 - Chair, NIH Special Emphasis Panel on Bioorganic and Synthetic Chemistry, 2005 - Co-Chair, ACS-NSF Committee and Workshop on the Molecular Basis of Life Processes, 2004-5 - External Examiner in Chemistry, University of Hong Kong, 2003-6 - Member MSFA Study Section, NIH 2006-7. - Founder and Principal Scientist, HepatoChem LLC, 2009-

J. T. Groves, page 3 Teaching at Princeton I have designed the Advanced Organic Chemistry course, CHM 403, that is aimed at junior and senior Chemistry majors and Chemical Engineers. This course weaves together elements of synthetic organic chemistry, biosynthetic pathways and modern drug design. I was pleased to see the enthusiastic evaluation of this course by the students: 4.4-4.8 for the five items most related to the quality of the lectures, stimulating independent thinking and the overall quality of the course. I have contributed to the planning and teaching of the new Integrated Quantitative Science Curriculum in collaboration with colleagues in Chemistry, Molecular Biology, Physics and Computer Science. I have also designed and taught Metals in Biology, CHM 544, with colleague Ed Stieffel. In 2013 Dorothea Fielder and I refreshed and reorganized this popular course, which is intended beginning graduate students and advanced undergraduates. Research Program The major thrust of our research program is at the interface of organic, inorganic, and biological chemistry. Many biochemical transformations, as well as important synthetic and industrial processes, are catalyzed by metals. Recent efforts in the lab have focused on the design of new, biomimetic catalysts and the molecular mechanisms of metal-catalyzed redox processes, including C-H bond hydroxylation and halogenation, the design and assembly of large scale membrane-protein-small molecule constructs, molecular probes of peroxynitrite-mediated protein nitration, pharmaceutical strategies for protection against peroxynitrite-mediated pathologies, and mechanisms by which pathogens acquire metabolic iron from host cells. Twenty most significant and selected recent papers

1. J. T. Groves, T. E. Nemo and R. S. Myers, Hydroxylation and Epoxidation Catalyzed by Iron-Porphine Complexes, J. Am. Chem. Soc., 1979, 101, 1032-1033. 759 citations

2. J. T. Groves, R. C. Haushalter, M. Nakamura, T. E. Nemo, B. J. Evans, High-Valent Iron-

Porphyrin Complexes Related to Peroxidase and Cytochrome P-450, J. Am. Chem. Soc., 1981, 102, 2884-2886. 711 citations

3. J. T. Groves and R. S. Myers, Catalytic Asymmetric Epoxidation with Chiral Iron Porphyrins, J. Am. Chem. Soc., 1983, 105, 5791-5796. 474 citations

4. J. T. Groves and R. Quinn, Aerobic Epoxidation of Olefins with Ruthenium Porphyrin

Catalysts, J. Am. Chem. Soc., 1985, 107, 5790-92. 462 citations 5. J. T. Groves and P. Viski, Asymmetric Hydroxylation, Epoxidation, and Sulfoxidation

Catalyzed by Vaulted Binaphthyl Metalloporphyrins, J. Org. Chem., 1990, 55, 3628-3634. 290 citations

6. J. T. Groves, J. Lee and S. Marla, Detection and Characterization of an Oxo-Manganese(V)

Porphyrin Complex by Rapid-Mixing Stopped-Flow Spectrophotometry J. Am. Chem. Soc., 1997, 119, 6269-6273. 296 citations.

7. N. Jin and J. T. Groves, Unusual Kinetic Stability of a Ground State Singlet Oxomanganese(V) Porphyrin. Evidence for a Spin-State Crossing Effect, J. Am. Chem. Soc., 1999, 121, 2923-2924. 168 citations

J. T. Groves, page 4 8. N. Jin, J. L. Bourassa, S. C. Tizio, and J. T. Groves, Rapid, Reversible Oxygen Atom

Transfer between an Oxomanganese(V) Porphyrin and Bromide. A Haloperoxidase Mimic with Enzymatic Rates. Angew. Chem. Int. Ed., 2000, 39, 3849-3851.

9. Karine Auclair, Zhengbo Hu, Dorothy M. Little, Paul R. Ortiz de Montellano and John T.

Groves, “Revisiting the Mechanism of P450 Enzymes Using the Radical Clocks Norcarane and Spiro[2,5]octane” J. Am. Chem. Soc., 2002, 124, 6020-6027.

10. Melanie S. Sanford and John T. Groves, “Anti-Markovnikov Hydrofunctionalization of

Olefins Mediated by Rhodium Porphyrins,” Angew. Chem. Int. Ed. 2004, 116, 598-600. 11. Minkui Luo, Evgeny A. Fadeev and John T. Groves, “Mycobactin-mediated iron acquisition

within macrophages”, Nature Chem. Biol. 2005, 1, 149-153. 12. Ning Jin, Mohammed Ibrahim, Thomas G. Spiro and John T. Groves, trans-Dioxo

Manganese(V) Porphyrins, J. Am. Chem. Soc., 2007, 129, 12416-12417. 13. Seth R. Bell and John T. Groves, A Highly Reactive P450 Model Compound I, J. Am.

Chem. Soc., 2009, 131, 9640-9641. 14. Jia Su and John T. Groves, Direct Detection of the Oxygen Rebound Intermediates, Ferryl

Mb and NO2, in the Reaction of metMyoglobin with Peroxynitrite J. Am. Chem. Soc., 2009, 131, 12979–12988.

15. Wei Liu and John T. Groves, Manganese Porphyrins Catalyze C-H Bond Halogenations, J.

Am. Chem. Soc., 2010, 132, 12847-12849. 16. Thomas P. Umile and John T. Groves, Catalytic Generation of Chlorine Dioxide from

Chlorite Using a Water-soluble Manganese Porphyrin, Angew. Chem. Int. Ed. 2011, 123, 721–724.

17. Wei Liu, Xiongyi Huang, Mu-Jeng Cheng, Robert J. Nielsen, William A. Goddard, III and

John T. Groves, Oxidative Aliphatic C-H Fluorination with Fluoride Ion Catalyzed by a Manganese Porphyrin, Science 2012, 337, 1322-1325. DOI: 10.1126/science. 1222327. (Cited in Chemical and Engineering News, Nature, Chemical World and the Princeton University home page).

18. Xiaoshi Wang, Sebastian Peter, Matthias Kinne, Martin Hofrichter, John T. Groves,

Detection and Kinetic Characterization of a Highly Reactive Heme–Thiolate Peroxygenase Compound I J. Am. Chem. Soc., 2012, 134, 12897–12900.

19. Wei Liu and John T. Groves Mn-Catalyzed Oxidative Benzylic C-H Fluorination Using

Fluoride Ion, Angew. Chem. Int. Ed. 2013, 52, 6024-6027.

20. Xiaoshi Wang, Sebastian Peter, René Ullrich, Martin Hofrichter, and John T. Groves, Driving Force for Oxygen-Atom Transfer by Heme-Thiolate Enzymes, Angew. Chem. Int. Ed. 2013, 52, 9238-9241.

J. T. Groves, page 5 Recent publications (2012-2015) 228. Callaghan, A. V.; Morris, B. E. L.; Pereira, I. A. C.; McInerney, M. J.; Austin, R. N.;

Groves, J. T.; Kukor, J. J.; Suflita, J. M.; Young, L. Y.; Zylstra, G. J.; Wawrik, B., The genome sequence of Desulfatibacillum alkenivorans AK-01: a blueprint for anaerobic alkane oxidation, Environmental Microbiology 2012, 14, 101-113.

229. Radovits, T.; Beller, C. J.; Groves, J. T.; Merkely, B.; Karck, M.; Szabo, C.; Szabo, G.,

Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass, European Journal of Cardio-Thoracic Surgery 2012, 41, 391-396.

230. Szabo, G.; Loganathan, S.; Merkely, B.; Groves, J. T.; Karck, M.; Szabo, C.; Radovits, T.,

Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation, Journal of Thoracic and Cardiovascular Surgery 2012, 143, 1443-1449.

231. Xiaoshi Wang, Sebastian Peter, Matthias Kinne, Martin Hofrichter, John T. Groves

Detection and Kinetic Characterization of a Highly Reactive Heme–Thiolate Peroxygenase Compound I J. Am. Chem. Soc., 2012, 134, 12897–12900; DOI: 10.1021/ja3049223

232. Mark J. Pouy, Erika M. Milczek, Travis M. Figg, Brooke M. Otten, Bruce M. Prince, T.

Brent Gunnoe, Thomas R. Cundari, and John T. Groves, Flavin-Catalyzed Insertion of Oxygen into Rhenium–Methyl Bonds J. Am. Chem. Soc., 2012, 134 (31), 12920–12923 DOI: 10.1021/ja3054139

233. Wei Liu, Xiongyi Huang, Mu-Jeng Cheng, Robert J. Nielsen, William A. Goddard, III, John

T. Groves, Oxidative Aliphatic C-H Fluorination with Fluoride Ion Catalyzed by a Manganese Porphyrin, Science, 2012, 337, 1322-1325, DOI: 10.1126/science. 1222327.

234. Harriet L. R. Cooper, Girish Mishra, Xiongyi Huang, Marilla Pender-Cudlip, Rachel N.

Austin, John Shanklin and John T. Groves Parallel and Competitive Pathways for Substrate Desaturation, Hydroxylation and Radical Rearrangement by the Non-heme Diiron Hydroxylase AlkB J. Am. Chem. Soc., 2012, 134, 20365–20375.

235. Swe-Htet Naing, Saba Parvez, Marilla Pender-Cudlip, John T. Groves, Rachel N. Austin

Substrate specificity and reaction mechanism of purified alkane hydroxylase from the hydrocarbonoclastus bacterium Alcanivorax borkumensis (AbAlkB) J. Inorg. Biochem. 2013, 121, 46-52.

236. Chris L. Bergstrom, Paul A. Beales, Yang Lv, T. Kyle Vanderlick, and John T. Groves Cytochrome c Causes Pore Formation in Cardiolipin-Containing Membranes Proc. Nat. Acad. Sci. U.S.A., 2013, 110 (16), 6269-6274.

237. Wei Liu and John T. Groves Mn-Catalyzed Oxidative Benzylic C-H Fluorination Using Fluoride Ion, Angew. Chem. Int. Ed. 2013, 52, 6024-6027.

238. Xiaoshi Wang, Sebastian Peter, René Ullrich, Martin Hofrichter, and John T. Groves, Driving Force for Oxygen-Atom Transfer by Heme-Thiolate Enzymes, Angew. Chem. Int. Ed. 2013, 52, 9238-9241.

J. T. Groves, page 6 239. Erin M. Bertrand, Ramaydalis Keddis, John T. Groves, Costantino Vetriani, Rachel

Narehood Austin, Identity and mechanisms of alkane-oxidizing metalloenzymes from deep-sea hydrothermal vents. Front. Microbiol. 2013, 4, 109. doi: 10.3389/fmicb.2013.00109

240. Dong Wang and John T. Groves, Efficient water oxidation catalyzed by homogeneous cationic cobalt porphyrins with critical roles for the buffer base, Proc. Nat. Acad. Sci. U.S.A., 2013, (39) 15579-15584.

241. Wei Liu, Xiongyi Huang and John T. Groves, Oxidative aliphatic C-H fluorination with manganese catalysts and fluoride ion, Nature Protocols, 2013, 8, 2348-2354.

242. John T. Groves, Enzymatic C-H Activation – Using push to get pull, Nature Chemistry, 2014, 6, 89-91.

243. Matthew E. O’Reilly, Dale R. Pahls, Joanna R. Webb, Nicholas C. Boaz, Subhojit Majumdar, Carl D. Hoff, John T. Groves, Thomas R. Cundari, and T. Brent Gunnoe, Reductive Functionalization of a Rhodium(III)-methyl Bond by Electronic Modification of the Supporting Ligand, Dalton Trans. 2014, 43 (22), 8273 - 8281. DOI: 10.1039/C4DT00234B

244. Dale R. Pahls, John T. Groves, T. Brent Gunnoe and Thomas R. Cundari, Theoretical Study

of Reductive Functionalization of Methyl Ligands of Group 9 Complexes Supported by Two Bipyridyl Ligands: A Key Step in Catalytic Hydrocarbon Functionalization, Organometallics, 2014, 33, 1936−1944.

245. Xiongyi Huang, Wei Liu, Hong Ren, Ramesh Neelamegam, Jacob M. Hooker and John T. Groves, Late Stage Benzylic C-H Fluorination with [18F]Fluoride for PET Imaging, J. Am. Chem. Soc. 2014, 136, 6842-6845.

246. George C. Fortman, Nicholas C. Boaz, Michael M. Konnick, Roy A. Periana, John T. Groves*, T. Brent Gunnoe*, Selective monooxidation of light alkanes using chloride and iodate, J. Am. Chem. Soc. 2014, 136, 8393–8401.

247. John T. Groves and Nicholas C. Boaz, Fishing for the Peroxidase Protons, Science, 2014, 345, 142-143.

248. Michael M. Konnick, Brian G. Hashiguchi, Deepa Devarajan, Nicholas C. Boaz, T. Brent Gunnoe, John T. Groves, Niles Gunsalus, Daniel H. Ess, and Roy A. Periana, Selective CH Oxy-Functionalization of Methane, Ethane, and Propane by a Perfluoroarene Iodine(III) Complex, Angew. Chem. Int. Ed., 2014, 126, on line DOI: 10.1002/ange.201406185.

249. Roman Stavniichuk, Hanna Shevalye, Sergey Lupachyk, Alexander Obrosov, John T. Groves, Irina G. Obrosova, Mark A. Yorek Peroxynitrite and protein nitration in the pathogenesis of diabetic peripheral neuropathy Diabetes/Metabolism Research and Reviews 03/2014; DOI: 10.1002/dmrr.2549

J. T. Groves, page 7 250. Ferryl Protonation in Oxoiron(IV) Porphyrins and its Role in Oxygen Transfer, Nicholas C.

Boaz, Seth R. Bell, and John T. Groves, J. Am. Chem. Soc. 2015, 137 (8), 2875–2885. DOI: 10.1021/ja508759t 251. Xiongyi Huang, Wei Liu, Jacob M. Hooker and John T. Groves, Targeted Fluorination with

Fluoride Ion via Manganese-Catalyzed Decarboxylation, Angew. Chem. Int. Ed., 2015, 54, 5241-5245. DOI: 10.1002/anie.201500399

252. Xiaoshi Wang, René Ullrich, Martin Hofrichter, and John T. Groves, The heme-thiolate ferryl of aromatic peroxygenase is basic and reactive, Proc. Nat. Acad. Sci. U.S.A., 2015, 112, 3686-3691.

253. Steven E. Kalman, Dominik Munz, George C. Fortman, Nicholas C. Boaz, John T. Groves*, T. Brent Gunnoe*, Partial Oxidation of Light Hydrocarbons using Periodate and Chloride Salts, Dalton Trans. 2015, 44, in press. DOI: 10.1039/ c5dt00558b.

254. Xiongyi Huang, Tova Bergsten and John T. Groves, Manganese-catalyzed Late-stage Aliphatic C-H Azidation, J. Am. Chem. Soc. 2015, 137, 5300–5303. DOI: 10.1021/jacs.5b01983.

255. Wei Liu and John T. Groves, Manganese Catalyzed C-H Halogenation, Accounts Chem. Res. 2015, in press.

256. John T. Groves, Cytochrome P450 Enzymes: Understanding the Biochemical Heiroglyphs

F1000: Faculty Reviews, 2015, in press. Recent Invited Conference and Symposium Lectures (2008-2014) 213. Center for Quantitative Biology Symposium, Princeton University, January 2008, invited speaker. 214. Metals in Biology Gordon Research Conference, Ventura, CA, January, 2008, invited speaker. 215. Isotope Effects Gordon Research Conference, Ventura, CA, February, 2008, invited speaker. 216. Symposium on Structure, Properties, and Function of Membranes and Membrane Related

Biomolecules," 235th ACS National Meeting, New Orleans, LA, April, 2008, invited speaker. 217. Symposium on "Chemistry and Health", ACS Mid-Atlantic Regional Meeting, Queensborough

College, NY, May, 2008, invited speaker. 218. Fifth International Symposium on Porphyrins and Phthalocyanines, Moscow, July, 2008, keynote

speaker. 219. 10th International Scientific Symposium on Dioxygen Activation and Homogeneous Catalysis

(ADHOC-2008), Venice, July, 2008, plenary lecturer. 220. Symposium on Siderophores: from Biogeochemistry to Medical Applications, National ACS

Meeting, Philadelphia, August 2008, invited speaker.

J. T. Groves, page 8 221. Symposium on Visualizing Chemistry: Advances in Chemical Imaging, National ACS Meeting,

Philadelphia, August 2008, invited speaker. 222. National Inorganic Chemistry Symposium, Kanazawa, Japan, September 2008, keynote speaker. 223. Colloque Chimie  et  Santé  au  service  de  l’Homme,  Paris,  October  2008,  Grand  Prix  

Award  address.    224.  Frontiers  in  Biological  Chemistry  Award  Address,  Max  Planck  Institute,  Mülheim,  

Germany,  February,  2009.    225.  F.  Albert  Cotton  Award  Symposium  in  honor  of  Kenneth  Karlin,  American  Chemical  

Society  National  Meeting,  Salt  Lake  City,  March,  2009,  invited  speaker.    226.  University  of  Michigan,  Department  of  Chemistry,  Collegiate  Professorship  Special  

Lecture,  Ann  Arbor,  April,  2009.    227.  14th  International  Conference  on  Bioinorganic  Chemistry,  Nagoya,  Japan,  July,  2009,  

invited  speaker.      228.  Symposium on Advanced Biological Inorganic Chemistry (SABIC-2009), Mumbai, India,

November, 2009, plenary lecturer. 229. Center for Catalytic Hydrocarbon Functionalization, Scripps Florida, January 2010, organizational

meeting, speaker. 230. Wayne State University, Department of Chemistry, Frontiers in Chemistry Lecture, February,

2010. 231. Princeton University, Keller Center 5th Innovation Symposium, invited speaker, winner 2010

Keller Center Innovation Prize, April 2010. 232. Center for Catalytic Hydrocarbon Functionalization, University of Virginia, May 2010, First

Summer Symposium, invited speaker. 233. Pennsylvania State University, Symposium on Frontiers in Metallobiochemistry, plenary lecturer,

June 2010. 234. Remsen Award Lecture, Maryland Section of the American Chemical Society, Johns Hopkins

University, June 2010. 235. Hans Fischer Award Lecture, International Conference on Porphyrins and Phthalocyanines, Santa

Ana Pueblo, New Mexico, July 2010. 236. Center for Catalytic Hydrocarbon Functionalization, CalTech, second winter meeting, January

2011, speaker. 237. Symposium on Recent Progress in Catalytic and Biomimetic Chemistry in Honor of Ronald

Breslow, 241st National ACS Meeting, Anaheim, CA, March 2011, invited speaker.

J. T. Groves, page 9 238. National Fresenius Award - Symposium in honor of Melanie Sanford, 241st National ACS Meeting,

Anaheim, CA, March 2011, invited speaker. 239. Symposium on Frontier Energy Research Symposium, 241st National ACS Meeting, Anaheim, CA,

March 2011, invited speaker. 240. The First Chemistry Faculty Colloquium in the New Frick Laboratory, May 2011, invited speaker. 241. Center for Catalytic Hydrocarbon Functionalization, University of Virginia, second summer

meeting, June 2011, invited speaker. 242. 17th International Conference on Cytochrome P450, Manchester, UK, June, 2011, keynote speaker. 243.  15th  International  Conference  on  Bioinorganic  Chemistry,  Vancouver  Canada,  August,  2011,  

invited  Jade  Anniversary  lecture.    244.  Symposium on Affordable Green Chemistry in Honor of Jack Kruper, 243rd National ACS

Meeting, San Diego, CA, March 2012, invited speaker. 245.  Symposium on Environmental Bioinorganic Chemistry in Honor of François Morel, 243rd National

ACS Meeting, San Diego, CA, March 2012, invited speaker. 246. International Conference on Porphyrins and Phthalocyanines, Jeju Island, Korea, July 2012, invited

speaker. 247. 245th National ACS Meeting, New Orleans, LA, April 8, 2013, Symposium on C-H Activation,

invited speaker. 248. International Conference on Cytochrome P450, University of Washington, Seattle, June 2013,

invited speaker. 249. Symposium on Bioinorganic Chemistry, University of Washington, Seattle, June 2013, invited

speaker. 250. Department of Energy EFRC Principal Investigator’s Meeting, Washington, DC, July, 2013,

invited speaker. 251. Frontiers in Inorganic Chemistry and Catalysis Symposium in Honor of Ronny Neumann,

Weizmann Institute of Science, Rehovot, Israel, October 2013, plenary lecturer. 252. Metalloporphyrins in Chemical and Biological Catalysis, Italian National Research Council,

University of Padova, October 2013, invited speaker. 253. University of Michigan, Department of Chemistry, Symposium in Honor of Melanie

Sanford, May, 2014, keynote speaker. 254. 8th International Conference on Porphyrins and Phthalocyanines, ICPP-8, Istanbul, Turkey,

June, 2014, invited speaker.

J. T. Groves, page 10 255. 19th International Symposium on Homogeneous Catalysis, Ottawa, Canada, July, 2014,

invited speaker. 256. 248th National ACS Meeting, San Francisco, CA, August, 2014, Symposium on Metal Ion

Interactions with Nitric Oxide and Reactive Oxygen Species in Chemistry and Biology, invited speaker.

257. Metals in Biology Gordon Research Conference, Ventura, CA, January, 2015, keynote lecture

(Thursday evening). 258. Rayson Huang Prize Lectureship, Department of Chemistry, University of Hong Kong, award

lecture, March 2015. 259. 249th National ACS Meeting, Denver CO. Inorganic Chemistry Award Symposium, March, 2015.