Supporting Clinical Research

AMIA Joint Summits on Translational Science

Library-based Support for Clinical and Translational Research: The Informationist

Jennifer A. Lyon, MS, MLIS, AHIP

Clinical Research Librarian

UF Health Science Center Libraries

jalyon@ufl.edu

March 10, 2011

http://www.research.ufl.edu/research/pdf/dsrannual2010.pdf

UF Health Science Center

Six Academic Colleges

Medicine

Nursing

Pharmacy

Dentistry

Veterinary Medicine

Public Health & Health Professions

Shands Healthcare

Two Teaching Hospitals•852 Beds Gainesville•696 Beds Jacksonville

Cancer Hospital

Children’s Hospital

Level I Trauma Centers

5 Major Research Institutes

• UF Clinical & Translational Science Institute

• McKnight Brain Institute

• UF Genetics Institute

• Shands Cancer Center

• Institute on Aging

• Emerging Pathogens Institute

• Founded in 2008 • Provides over 40 services to UF&Shands researchers

– Phase I Clinical Trial Unit

– Clinical Research Center

– Core Laboratory Services

– Project ‘Navigators’ (consultant services)

• Provides various educational programs– KL2 and TL1 awards

– Research Coordinator Certificate Program

– MD-PhD Training

– MSCI

About the HSC LibrariesHealth Science Center Library (Gainesville)

11 Liaison Librarians •7 Subject Specialists

•4 Functional and Subject Specialists)

– Consumer Health and Community Engagement

– Distance Education

– Bioinformatics

– Clinical Research

Borland Library (Jacksonville)

•3 Librarians (Including Clinical Librarian starting Mar 15, 2011)

Librarians hold full tenure-track faculty status;

5 new hires in 2010: doubling size of Biomedical Health & Info Services Dept.

The Clinical Research Librarian

• Library competed for funding• UF Provost re-designated position for CTSI support• Hired July 23, 2010• Liaison to

– CTSI

– Emergency Medicine

– Pathology, Immunology & Laboratory Medicine

• Functions as cross-disciplinary expert in clinical research

Developing a New Role: Challenges

• No ‘role models’

• Complexity of clinical research

• High learning curve – Multiple Agencies and Regulations

– Unique to each institution

– New vocabulary (IRB, RAC, IND, DSR, RKRS…)

– Complex web of relationships to develop

Developing a New Role: Opportunities

• CTSI members involved in hiring committee • UF highly invested in clinical & translational

research• Other librarian-involved research collaborations in

development• Library expanding clinical services & support for

EBP• Previous 8 years experience in Emergency

Medicine facilitates new ED research collaborations at UF

CTSI Integration

• Serve in CTSI Regulatory Knowledge & Research Support (RKRS) Group

• Collaborate with RKRS members on studies/grants

• CTSI requested library instruction in academic course

• CTSI added literature searching services to RKRS portal

• Participation in CTSI Strategic Planning Retreat

• Representing UF on national CTSA Research Networking Committee

• Representing UF on national REDLOC committee

About the RKRS

CTSI Regulatory Knowledge & Research Support program

Develop a guided, single ‘pathway’ for clinical investigators to move from ‘idea’ to completed clinical study

Clinical Research Center

Institutional Review Board

Research Administration &

Compliance

Dept. of Sponsored Research

Office of Technology Licensing

Dental Research Unit

REDCap Data Capture/Management

Quality Assurance

Research Subject Advocacy

Biostatistics

BioRepository

Health Science Center Library

Research Ethics Project

RKRS-facilitated Research Team

Focus: Conflict of Interest in UF College of Medicine

Team Members:

•UF COM’s Conflict of Interest Officer

•RKRS program director

•REDCap services director/biostatistician

•Health and Science Communications doctoral student

•CTSI research project manager

•Clinical Research Librarian

Manuscript in submission process

Teaching

• Instructor in the CTSI’s credit-bearing course “Introduction to Clinical and Translational Research” (summer 2010, 2011)

• Taught literature searching skills to CTSI MD-PhD students fall 2010

Research Networking

• Representing UF on the CTSA’s national Research Networking Committee

• Participating on the VIVO Outreach Team at UF

Beyond the CTSI

• Emergency Medicine

• Brain Cancer Patient/Caregiver Education

• NIH Public Access Policy Services

• Support for Systematic Reviews

• In-house Training for Librarians

Emergency Medicine Research

• Joined research team of Dr. Latha Stead, ED Chief of Clinical Research. – Collaborating on systematic & structured reviews

• Providing training for ED research associates

• Providing mediated literature searches for ED faculty

• Serving as liaison librarian for Emergency Department– Attending resident teaching conferences

– Providing training for residents & faculty

– Selecting library materials

– Developing LibGuide for Emergency Medicine e-resources

Brain Tumor Patient Education

• Supporting library colleague on an interdisciplinary study of the information needs of brain tumor patients and their caretakers

• Collaborative team led by Dr. Erin Dunbar of the McKnight Brain Institute

NIH Public Access Project

• Leading a team of librarians • Developing library support services

– Creating materials including a LibGuide

– Creating prepared presentations

– Identifying UF departments not fully compliant

– Collecting information on Publisher’s PMC policies

– Investigating the value of providing ‘third-party submission’ services

Systematic Reviews

• Attended a 2.5 day workshop on writing Systematic Reviews at U. Pittsburgh

• Training Colleagues

• Expanding library services to patrons– Classes– Consultations– Collaborations

Future Goals

• Increase support for investigators writing IRB protocols

• Develop relationship with IRB

• Develop further opportunities for clinical research collaborations

• Train librarians in evidence-based practice

• Support and develop point-of-care clinical librarianship services and leverage on these to increase involvement in clinical research

In Conclusion

• The role of a librarian (“informationist”) specializing in clinical research is both innovative and exciting.

• There are huge opportunities and significant challenges ahead as we develop this new position

• This will serve as a role model for other libraries supporting clinical and translational research in the future