Jefferies 2019 Global Industrials Conference Slides FINAL · Microsoft PowerPoint - Jefferies 2019 Global Industrials Conference Slides FINAL Author: denardo Created Date: 8/6/2019

Jefferies 2019 Global Industrials Conference

August 6, 2019

Cautionary Notes

2

Cautionary Notes

FORWARD-LOOKING STATEMENTS

This presentation and oral statements accompanying this presentation contain forward-looking statements, andany statements other than statements of historical fact could be deemed to be forward-looking statements. These forward-looking statements include, among other things, statements regarding future events, such as expected revenue,gross margin and production volume in 2019, including related growth rates, the anticipated development, scalingand commercialization of Amyris’s product pipeline and introduction of new products, including HMOs, vitamins, and F&Fand cannabinoid ingredients, expected growth of Amyris’s Clean Beauty, F&F and Sweetener businesses, the anticipatedsize of the global beauty and personal care market, including categories thereof, as well as Amyris’s entry into certain ofsuch market categories, including the timing thereof, expectations regarding Amyris regaining compliance with its Securitiesand Exchange Commission and Nasdaq filing obligations, including the timing thereof, anticipated financing activity andrelated improvements to Amyris’s capital structure and balance sheet, and expectations regarding Amyris’s financial andoperational results and ability to achieve its business plan in 2019 and beyond. These statements are based onmanagement’s current expectations and actual results and future events may differ materially due to risks anduncertainties, including risks related to Amyris’s liquidity and ability to fund operating and capital expenses, risks related topotential delays or failures in development, production and commercialization of products, risks related to Amyris's relianceon third parties, and other risks detailed from time to time in filings Amyris makes with the Securities and ExchangeCommission, including Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q and Current Reports on Form 8-K.Amyris disclaims any obligation to update information contained in these forward-looking statements, whether as a result ofnew information, future events, or otherwise.

Copyright © 2019 Amyris, Inc. All rights reserved

We are making the world’s best performing,

purest molecules in a sustainable way - and

making them accessible for all.Make good. No compromise.®

3Copyright © 2019 Amyris, Inc. All rights reserved

Saving 1MM children from malaria with an affordable cure.

Saving over 3MM sharks a year while making the world’s best

moisturizer.

Transforming flavors and fragrances, like patchouli, into clean, sustainable

ingredients without damage to the environment.

Now, we’re tackling obesity and diabetes. We are bringing back

the sweet life for everyone.

Our sustainable sugarcane fermentation is helping Amyris do our part toward:


From Idea To Industrial-Scale, Making Natural Sustainable

1 Engineer microbial factories

Emeryville, CA, USA(near San Francisco)

2Produce ingredients using our industrial fermentation technology

Brotas, BrazilCMOs

3Commercialize through collaboration partners and direct to consumer

Formulate and sell own products

Copyright © 2019 Amyris, Inc. All rights reserved 5

#1 Synthetic Biotechnology

Platform

Fully integrated production of high

value products

Proven Commercial Platform

Ingredients Consumer

A fully integrated R&D platform, purpose-built to disrupt.

Automated Strain

Engineering

High-throughput screening

Automated Design

Analytics

Fermen-tation

Manufac-turing

Data capture, machine

learning, human intelligence


0.5 Liter 200,000 Liter

Small Scale0.5

Co

mm

erc

ial

Sc

ale

0.6 0.7 0.8 0.9 1 1.1

0.5

0.6

0.7

0.8

0.9

1

1.1

We are the leader at delivering best in class natural products at industrial scale


Lower average product develop-ment cost

90%

Increased productivity

500%Accelerating Disruption

Decreased average time to market

80%

45

40

35

30

25

20

15

10

5

02012 2019

Product 1 Product 2 Product 3 Product 5Product 4

From first strain to first pilot run

Mo

nth

s

Throughput 100x8Copyright © 2019 Amyris, Inc. All rights reserved

Delivering Strong Recurring Growth & Expanding Profitability

2018 20192017* Adjusted for loss making product sales on contracts and one time revenues

Gross Margin % 49% 52% 55%- 65%


Product

License/Royalties/Collab

Product CAGR98%

Our Products are Delivering the Leading Industry Growth

Farnesene Derived 201%

Fragrance 214%

Fragrance In-Market

Farnesene Derivatives 172%

Skin Care 301%

Skin Care 163%

High Performing Polymer 129%

Branded Product Sales +277%

Ingredient Sales +61%

2016-2019 REVENUE CAGR

Copyright © 2019 Amyris, Inc. All rights reserved10

Molecules ‘18-’19 Growth

Fermentation 234%

Sweetener 5800%

Flavor 2000%

Fragrance 422%

1st Fragrance 175%

Cosmetic Active 67%

Cosmetic Active Scaling up

Fragrance Scaling up

Fragrance Scaling upNote: 2018 Actual vs.2019 Plan Volume

Molecule Revenue Profile From Launch

11 Copyright © 2019 Amyris, Inc. All rights reserved

Molecule 2 CAGR : 56%

Molecule 1CAGR : 85%

Source: consumption per value share reports and/or distributor data

12Copyright © 2019 Amyris, Inc. All rights reserved12

Market Leadership

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A product marketing company powered by the world’s leading science

1) HMOs2) Vitamins3) Cannabinoids

Fastest Growing in:1) Clean Beauty2) Sustainable F&F Ingredients3) The best tasting Natural Sweetener

Disruptive Product Pipeline

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Global Skincare market breakdown (2017, $B) Skincare market distribution channels (2017, $B)

Beauty & Personal Care $300 Billion Market

Beauty & personal care global market sizes by HPC category (2017, $B)

1 – Euromonitor 2017 Copyright © 2019 Amyris, Inc. All rights reserved


Biossance - Fastest Growing Clean Skin Care Brand

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Fastest growing Clean Skin Care brand in North America.

Powered by Squalane.

15

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2012 2013 2014 2015 2016 2017 2018 2019

3000+ Brands

Copyright © 2019 Amyris, Inc. All rights reservedSource: Aprinnova Distributor Data

Neossance™ Squalane Growth

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We Are Just Starting The DisruptionA Disruptive Business Model

• From one molecule, we are leading a new category in the Beauty Industry – Clean Beauty

• Driven by the most powerful ingredient sustainably sourced to disrupt the beauty industry

• Setting the standards for consumers with the leading consumer brands in Clean Beauty


Sugar is natural & tasty, but dangerous. A vicious cycle of pleasure and guilt.

until now...



100% SWEET

• 0 bitter aftertaste

• 0 glycemic index

• 0 calories

• 0 GMO

• fermented for a healthy gut

100% SUSTAINABLE

• responsibly grown sugarcane

• 20x less farmland to produce

• 1 clean fermentation process

• all recycled cane-based packaging

• 0 waste (almost, we’re working on it)

Sweet for Me, Sweet for the Planet.


© 2019 Amyris, Inc. All rights reserved.

• Executed $300 million Cannabinoid development, licensing and commercialization agreement with additional long-term royalty stream. Largest Cannabinoid agreement in industry to date.

• Amyris in partnership with DSM, moving quickly toward the commercialization of our first Human Milk Oligosaccharide (HMO) molecule, which is in the family of sugars from mother's milk. We will plan to commercialize a series of molecules in this category to improve the nutrition of infants throughout the world.

• Amyris in partnership with Yifan is developing a portfolio of sustainably sourced vitamins to reduce the cost and make some of the leading vitamins in the world more competitive and available for all.

• Amyris continues to grow our strategic partnership with Firmenich and Givaudan to continue as the leading supplier of the best performing, sustainably sourced ingredients for the Flavor and Fragrance industry.

Cannabinoids, Vitamins, HMO’s and Sustainable Flavor and Fragrances

25


Warrant Holders Composition and Total Shares


Estimated warrant exercise potential proceeds of up to $172M subject to certain conditions.

Debt Schedule – July 2019

Insi

de

rs

Debt

$ millions Maturity Rate Cash/PIK Jul-19

6% convertible notes Dec-21 6.0%-18.0% Cash/Shares 73.0

TOTAL Aug-19 10.5% Cash 9.7 Foris Jul-21 14.50% Cash 36.0 Foris Short Term Loans Various 34.5 DSM Loan Dec-21 10.0% Cash 25.0 Ginkgo note Oct-22 10.5% Cash 12.0 Nikko note 2 Dec-20 5.0% Cash 3.0 Nikko note 1 Dec-29 5.0% Cash 3.0 Nikko Aprinnova note B Aug-19 2.75% Cash 1.1 Other loans Various Various Cash 0.6 Total Debt (ex-debt discount) 197.9 Unamortized debt discount (12.6) Total Debt (net of debt discount) 185.3

Expected to convert into shares once Amyris is SEC filing compliant -34.5Total Debt (if Foris Short Term Loans are excluded) 150.8

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World Class Board and ManagementAmyris Board of Directors• John Doerr, Executive Chairman, Kleiner Perkins Caufield & Byers• Geoff Duyk, Managing Partner, Circularis Partners• Philip Eykerman, EVP Strategy & MNA, Royal DSM• Christoph Goppelsroeder, CEO of Nutrition Business, Royal DSM• Lisa Qi, CEO & Founder, Daling Family Company• Frank Kung, Managing Partner, Vivo Capital• Jim McCann, Chairman, 1-800-Flowers• Steve Mills, former CFO, Archer-Daniels-Midland (ADM)• Carole Piwnica, Naxos Capital Partners• Neil Williams, former CFO, Intuit• Pat Yang, former EVP of Technical Operations, Roche-Genentech

28 Copyright © 2019 Amyris, Inc. All rights reserved*Select management of key business areas indicated

Amyris Management*• Eduardo Alvarez, Chief Operating Officer• Caroline Hadfield, President of Pipette Baby Brand• Catherine Gore, President of Biossance• John Melo, President & CEO• Jonathan Wolter, Interim CFO• Kathy Valiasek, Chief Business Officer


What is Our Competitive Advantage?

1) We own terpenes, terpenes are nature• 666 patents issued US & foreign with 240 patents pending• First biotech company that has engineered, scaled up and

attained market leadership in: Clean Beauty F&F Ingredients Natural Sweetener

2) Fully integrated business from target molecule to industrial production and commercialization

3) The most products industrialized and fastest growing product revenue of any synthetic biology company in the world


Make good.No compromise.

• Our ingredients are inside over $7B of consumer retail purchases

• You’ll find our ingredients in over 3,000 of the world’s leading personal care and beauty brands

• Our Biossance Skin Care Brand is the fastest growing Skin Care Brand in North America

• We have the leading product in the natural Sweetener market. We are committed to a healthier planet and a sweet life for all! We want to help reduce risk of Diabetes and Obesity

• Most profitable product portfolio in the industry

Good for People

Good for the Planet

Good for Business

™


Documents

Jefferies 2019 Global Industrials Conference Slides FINAL · Microsoft PowerPoint - Jefferies 2019 Global Industrials Conference Slides FINAL Author: denardo Created Date: 8/6/2019