Jair Lage de Siqueira-NetoResearch Interests:

• Discovering new chemotherapies to treat:

• Host-parasite interactions

• Microbiome / Natural products

Chagas Disease Leishmaniasis Human African Trypanosomiasis

Core Expertise

• Screening Assay Development

• High Content Screening (visual-based assays)

• Kinetoplastid-caused diseases (Biology and animal models)

SSPPS Screening Platform (4th floor)

Envision

ATS

Biomek FXImageXpress

Robotic Arm

In vivo Imaging System (IVIS)

Proposed Collaborations with SSPPS Faculty

• Targeting T. cruzi CYP51 (Larissa Podust)

• Screening of Natural Products (Bill Gerwick)

• Functional High-Content screening (Geoffrey Chang)

• Lead optimization for HAT (Dionicio Siegel)