Jacqueline F. McGinty, Ph.D. Interim Dean, College of Graduate Studies NIDA T32 Director Dept. of...
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Jacqueline F. McGinty, Ph.D. Interim Dean, College of Graduate Studies NIDA T32 Director Dept. of Neuroscience and Neurobiology of Addiction Research Center
Jacqueline F. McGinty, Ph.D. Interim Dean, College of Graduate
Studies NIDA T32 Director Dept. of Neuroscience and Neurobiology of
Addiction Research Center Medical University of South Carolina
Career Development in Translational Addiction Research
Slide 2
Career Development in Drug Abuse Research Predoctoral
T32->F30/F31 Postdoctoral T32->F32 K Awards NIDA Mentored
Clinical Scientists Development Program Award in Drug Abuse and
Addiction (K12) PAR- 13-163 (K12) - March 28, 2013 PAR- 13-163
(K12) - March 28, 2013 NIH Pathway to Independence Award (Parent
K99/R00) PA-14-042 (K99/R00) - December 19, 2013 PA-14-042
(K99/R00) - December 19, 2013 Mentored Quantitative Research
Development Award (Parent K25) PA-14-048 (K25) - December 19, 2013
PA-14-048 (K25) - December 19, 2013 Mentored Patient-Oriented
Research Career Development Award (Parent K23) PA-14-049 (K23) -
December 19, 2013 PA-14-049 (K23) - December 19, 2013 Mentored
Clinical Scientist Research Career Development Award (Parent K08)
PA-14-046 (K08) - December 19, 2013 PA-14-046 (K08) - December 19,
2013 Mentored Research Scientist Development Award (Parent K01)
PA-14-044 (K01) - December 19, 2013 PA-14-044 (K01) - December 19,
2013 Independent Scientist Award (Parent K02) PA-14-045 (K02) -
December 19, 2013
http://www.drugabuse.gov/funding/research-training-career-development
http://report.nih.gov/nihdatabook/index.aspx?catid=14 Fellows on
NRSA grants, compared with their colleagues without NRSA support,
are more likely to be appointed as faculty and more likely to apply
for and receive independent NIH support. NIDA Mentoring Guide
Slide 3
Kirschstein-NRSA pre-doctoral fellowships (F31) Competing
applications, awards, and success rates
Slide 4
Kirschstein-NRSA post-doctoral fellowships (F32) Competing
applications, awards, and success rates
Slide 5
Research Career Development Awards
Slide 6
Research Career Development Award Success Rates
Slide 7
http://www.drugabuse.gov/publications/mentoring-guide-drug-abuse-researchers/preface
"NIDA offers a strategic set of funding mechanisms to support the
development of research scientists through various stages of their
careers. These awards are designed to ensure that scientists of the
very highest caliber will be available in adequate numbers and in
the appropriate research areas and fields to meet the Nation's drug
abuse and addiction needs." Nora D. Volkow, M.D., NIDA Director The
guide was developed over several years with the help of both
mentors and mentees. Work began at a workshop of the College on
Problems of Drug Dependence (CPDD) in 2003, continued at a career
development seminar of CPDD in 2005, and culminated at the National
Institute on Drug Abuse (NIDA) Research Training Institute in 2006.
NIDA Mentoring Guide
Slide 8
NIDA Strategic Plan 2016-2020 The current NIDA Strategic Plan
was published in 2010. Since that time, there have been major
advances in the science of drug abuse and addiction. In the
Strategic Plan for 20162020, NIDA seeks to harness the latest
research technologies and apply them to the ever-evolving substance
abuse landscape. Toward this goal, NIDA staff developed a draft set
of strategic priorities and are seeking feedback to guide the
development of NIDAs Strategic Plan. See more at:
http://grants.nih.gov/grants/guide/notice-
files/NOT-DA-15-005.html#sthash.UuANcvIX.dpuf
Slide 9
NIDA Strategic Priorities 2016-2020 Increase our knowledge of
biological, behavioral, environmental, and developmental factors
involved in risk and resilience for drug use and addiction
Integrating animal models, behavior, genetics, epigenetics, and
other molecular biomarkers for drug abuse and addiction Understand
the developmental trajectory of addiction and individual
heterogeneity Improve our understanding of brain circuits related
to drug abuse and addiction at the cellular, circuit, and
connectome levels, including: Normal development and function
across the lifespan including mechanisms of reward, self- control,
and conditioning Drug effects on neuroplasticity, neural structure,
and circuit function across the stages of addiction Neurobiological
correlates of recovery Neural-glial, -immune, and neuroendocrine
interactions Better define the interactions between addiction and
pain, including molecular, genetic, behavioral, and
neural-circuit-related factors, to guide the development of
alternate treatment strategies for pain patients Improve our
understanding of the interaction between addiction and co-occurring
conditions Elucidate the impact of mental health, HIV, HCV, pain,
etc. on addiction; Understand molecular mechanisms of latent HIV
reservoirs in the brains of substance-abusing populations Basic
Neuroscience: Improve our understanding of the basic science of
drug use, addiction, vulnerability to addiction, and recovery See
more at: http://grants.nih.gov/grants/guide/notice-files/NOT-DA-15-
005.html#sthash.UuANcvIX.dpuf
Slide 10
NIDA Strategic Priorities 2016-2020 Support the development of
novel, evidence-based, targeted prevention and treatment
interventions including social, behavioral, pharmacological,
vaccines, and brain stimulation therapies (e.g., transcranial
magnetic stimulation, direct current stimulation, etc.) Accelerate
the identification of promising targets and ligands to accelerate
new drug discovery and development Accelerate medications
development for SUDs Focused development efforts on: Addictions
without an FDA approved treatment Detoxification Overdose
prevention or reversal Accelerating neurobiological recovery
Addressing comorbidities (MH, HIV, HCV, pain) Develop techniques to
measure and improve patient compliance in clinical trials Identify
measures other than abstinence that can reliably assess SUD
treatment outcomes Identify biomarkers of addiction, resilience,
and recovery to enable personalized treatment Clinical and
Translational Science: Support the development of new and better
interventions and treatments that incorporate the diverse needs of
individuals with Substance Use Disorders (SUDs) See more at:
http://grants.nih.gov/grants/guide/notice-files/NOT-DA-15-
005.html#sthash.UuANcvIX.dpuf
Slide 11
NEED FOR TEAM SCIENCE: Approaches from single disciplines have
done much to advance drug abuse research, but technological,
methodological, and other advances have established the need for
increasingly multidisciplinary approaches to address more complex
questions. DIVERSITY: The demographics of students and mentees are
changing continually. As the demographic characteristics of mentees
shift, so must the training of mentors. NOT-OD-15-053
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-15- 053.html
Release Date: January 12, 2015 Purpose
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-15- 053.html
The purpose of this notice is to provide an updated diversity
statement that describes NIH's interest in the diversity of the
NIH-funded workforce. NIDA Strategic Plan 2016-2020
Slide 12
Trends in race/ethnicity of NIH-supported Ph.D. recipients
White Asian/Pacific Islander Hispanic Black
Slide 13
BIOMEDICAL RESEARCH WORKFORCE WORKING GROUP REPORT National
Institutes of Health June 14, 2012
Slide 14
US Graduate Degrees Awarded, by Field Basic Biomedical MDs
Slide 15
Years Biomedical PhDs Spend in Postdoctoral Training Most
US-trained biomedical PhDs spend fewer than 5 years in postdoctoral
positions, although that number has been grown since 2003
Slide 16
Biomedical Postdoctoral Researchers by Type of Support
Slide 17
Age at First PhD, First Non Postdoctoral Job, First Tenure
Track Job, for US trained Doctorates First PhD First non-postdoc
Job First tenure-track Job
Slide 18
Distribution of NIH RPG Principal Investigators by Degree Type
Researchers with an MD or MD/PhD comprise around 30% of NIH-funded
Principal Investigators (PIs). The percentage of MDs has declined
and the percentage of MD/PhDs has increased slightly in the past
few years. PhD MD MD/ PhD
Slide 19
Estimated Change in Employment Levels in Biomedical Occupations
Medical Scientists Postsecondary Teachers Biological Scientists
Biochemists Survey of Doctorate Recipients