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Durability of Effect in Double-blind Phase. Item. Active treatment. Placebo. value. P. 25% of patients had LTR. By day 34. By day 7.
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Item Active treatment Placebo P value
25% of patients had LTR By day 34 By day 7 <0.0001
LTR by end of study 32% of patients 61% of patients <0.0001
Worsening fatigue (MAF scale)
By day 119 By day 27 <0.0001
Worsening in Overall Sleep Problems Index (MOS-sleep scale)
By day 42 By day 14 <0.0001
Presented at EULAR 2007.
Durability of Effect in Double-blind Phase
