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Introduction to emerging infectious diseases
October 17, 2017
Disease Control and Prevention Center
National Center for Global Health and Medicine
Shinichiro Morioka, M.D.
Today`s content
1. Previous events of EIDs in Japan (Dr. Morioka)
2. Current Japanese system against infectious diseases (Dr. Kutsuna)
3. Powered Air-Purifying Respirator (Dr. Ohta)
Population: 127 million
8 Regions, 47 Prefectures
Japan National Tourism Organization
Japan
Japanese National Center
Japan has 6 national centers.
Specialized for
Infectious disease
Pediatric disease
Elderly disease
Heart disease
Psychological disease
Cancer
Our Mission
Management of the Risks of Infectious Diseases from a Global Viewpoint
Organization Chart of DCC
Disease Control and Prevention Center (DCC)
Division of
Infectious DiseasesTravel Clinic
Division of Preparedness
and Emerging Infections
Isolation unit for emerging infectious
disease
Unit for Highly Lethal
Infectious Diseases
4 beds
Highly Infectious and Lethal Diseases Unit, 10 beds
NCGM has 4 beds.
Each Other hospital has 2 beds.
High Level Isolation Unit in NCGM
Building constructed in 2003, and immediately accepted suspected
SARS cases.
Located close to the National Institute of Infectious Diseases
(laboratory services easily available).
Training Session
Emerging/re-emerging Infectious Diseases
WHO
Emerging Infectious Disease Events in the Past 30 Years in Japan
Events Place Year
Lassa fever,
imported from Sierra Leone
Tokyo 1987
Anthrax bioterrorism incident Tokyo 1993
Outbreak of EHEC O157 Western Japan 1996
SARS, imported from Taiwan Western Japan 2003
Avian influenza H5N1,
no human case
Western Japan 2004
Pandemic influenza H1N1 Across Japan 2009
Dengue, autochthonous Tokyo 2014
Suspected Ebola Across Japan 2014-15
Emerging Infectious Disease Events in the Past 30 Years in Japan
Events Place Year
Lassa fever,
imported from Sierra Leone
Tokyo 1987
Anthrax bioterrorism incident Tokyo 1993
Outbreak of EHEC O157 Western Japan 1996
SARS, imported from Taiwan Western Japan 2003
Avian influenza H5N1,
no human case
Western Japan 2004
Pandemic influenza H1N1 Across Japan 2009
Dengue, autochthonous Tokyo 2014
Suspected Ebola Across Japan 2014-15
Scientific Data 1: 140004 (2014)
Dengue
RAPID RISK ASSESSMENT Outbreak of Ebola virus disease in West Africa, 10th update, 14 April 2015
4
Figure 1. Distribution of EVD cases by week of reporting; Guinea, Sierra Leone, Liberia, Nigeria,
Senegal and Mali; week 48/2013 to week 15/2015, as of 5 April 2015
* In week 45/2014, WHO carried out a retrospective correction to the data which resulted in 299 fewer cases and a negative value for new cases in week 45 (not plotted) [12]. ** According to WHO, the marked increase in the cumulative total number of cases in week 43 is due to a more comprehensive assessment of patient databases which resulted in 3 792 additional cases. These cases have actually occurred throughout the entire epidemic period. The green trend line is based on a five-week moving average, plotted on the fifth week of the moving average window. The figure includes cases in Nigeria (20), Senegal (1) and Mali (4) [11].
Figure 2. Distribution of confirmed cases of EVD by week of reporting; Guinea, Sierra Leone and
Liberia; weeks 46/2014 to 15/2015
ECDC. Rapid risk assessment. April 15, 2015
2013.12〜
2014.5
2014.6〜
2014.11
2014.12〜
2015.12
2013-2016 Outbreak of
Ebola virus disease in
West Africa
Nosocomial spread of
MERS in South Korea
Current Classification of Highly Infectious Diseases in Japan
Novel
Lethal, pathogens
not identified
Diseases with unknown pathogens,
ex. SARS before SARS-coronavirus identified
Category 1
Lethal, BSL4
pathogens
Viral hemorrhagic fevers, ex. Ebola
Smallpox
Plague
Category 2
Lethal, epidemic-
prone
SARS and MERS
Avian influenza H5N1 and H7N9
Tuberculosis
Polio and Diphtheria
National Agencies for Infectious Disease Control
MHLW
NIID
Qua-rantineOffice
NCGM
NIID: National Institute
of Infectious Diseases
BSL4 laboratory
Epi & Laboratory
NCGM: National Center for
Global Health and Medicine
Case management & IPC
MHLW: Ministry of Health,
Labour and Welfare
Coordination
Open discussions