OOOO ABSTRACTS

Volume 117, Number 2 Abstracts e167

PE-180 - INTRANEURAL NEUROFIBROMA. SABRINANOGUEIRA DE MORAES, SILVIA PAULA DE OLIVEIRA,DANIELLE RESENDE CAMISASCA, OSLEI PAES DEALMEIDA, REBECA SOUZA AZEVEDO. FACULDADEDE ODONTOLOGIA DE NOVA FRIBURGOeUFF.

Neurofibroma is a common tumor of peripheral nerve, butintraneural development is uncommon. This proliferation ofSchwann cells and perineural fibroblasts occurs mainly in the skinbut the oral cavity may be affected. Woman, 45, had a smallpainless nodule on the dorsum of the tongue that had been presentfor 10 years. The differential diagnosis included extraneuralneurofibroma and palisaded encapsulated neuroma. Microscopicanalysis showed a well-circumscribed tumor mass that wasdemonstrating proliferation within the perineurium. It wasimmunologically positive for S-100, CD34, NSE, EMA, andGLUT-1 in peripheral bundles of spindle-shaped cells with wavynuclei, collagen bundles, and numerous mast cells identified forCD56; it was negative for NF antibody. Treatment was surgicalexcision; prognostically, no recurrence has been noted over 2years of follow-up. The correct diagnosis is important becausepatients should be evaluated for possible neurofibromatosis andmalignant transformation, although that is rare.

PE-181 - INTRAORAL GRANULOCYTIC SARCOMA INA PATIENT WITH MYELODYSPLASTIC SYNDROMEPLUS ACUTE MYELOID LEUKEMIA. FILIPE NOBRECHAVES, FRANCISCO SAMUEL RODRIGUESCARVALHO, RÉGIA MARIA DO SOCORRO VIDAL DOPATROCÍNIO, FABRÍCIO BITU SOUSA, ANA PAULANEGREIROS NUNES ALVES, FÁBIO WILDSON GURGELCOSTA, KARUZA MARIA ALVES PEREIRA. FEDERALUNIVERSITY OF CEARA - CAMPUS SOBRAL.

Granulocytic sarcoma (GS) is a rare localized immaturegranulocytes infiltrate found in extramedullary sites or boneaccording to the new World Health Organization classificationfor lymphoid and hematopoietic neoplasms. Intraoral GS isalso rare and is frequently associated with acute myeloid leu-kemia. Woman, 42, with myelodysplastic syndrome initiallynoticed a painful swelling on the right posterior maxilla ofuncertain onset. Incisional biopsy was performed, and micro-scopic evaluation revealed a lymphoproliferative lesion.Immunohistochemical profile with PAX 5, Tdt, CD 3, CD 79a,CD 34, CD 117 (C-kit), and MPO antibodies disclosed the finaldiagnosis of GS. MPO antibody reaction was positive in 90%of tumor cells. Later the patient was diagnosed with acutemyeloid leukemia. Currently, the patient is undergoing achemotherapy regimen. We addressed the clinicopathologicalfeatures of a rare case of myelodysplastic syndrome trans-formation into an acute myeloid leukemic form with thedevelopment of intraoral GS.

PE-182 - JAW OSTEONECROSIS CAUSED BY PRO-LONGED USE OF CORTICOSTEROIDS IN A PATIENTWITH MYCOSIS FUNGOIDES: CASE REPORT. ANAPAULA SILVA, ÉRICA PATRÍCIO, CELSO AUGUSTOLEMOS, FÁBIO ABREU ALVES. FACULDADE DEODONTOLOGIA DA UNIVERSIDADE DE SÃO PAULO.

Avascular bone necrosis normally occurs after trauma, indiabetic patients, with chronic alcoholism, and in chronic in-flammatory diseases treated with corticosteroids. It usually affectsthe knee, hip, and ankle, but rarely includes the jaws. Woman, 78,was referred to the stomatology department to evaluate a painful

bone exposure that occurred after extraction of tooth #37 1 monthpreviously. The patient was given corticosteroids for mycosisfungoides over the course of 18 months. On clinical examination,necrotic bone exposure was observed. Panoramic resultsdemonstrated a diffuse osteolytic lesion. The diagnosis wasosteonecrosis associated with chronic corticosteroid use. Thepatient was referred for surgical treatment, but passed away 2weeks before the appointment. Avascular bone necrosis is notcommon in the jaw. Corticosteroid therapy contributes to thepathogenesis of avascular bone necrosis by suppressing osteo-blastic function. Treatment consists of surgery debridement andantibiotics.

PE-183 - JUVENILE OSSIFYING FIBROMA OF THEMANDIBLE. MONICA GHISLAINE OLIVEIRA ALVES,ANDRÉ CAROLI ROCHA, CELINA FAIG LIMA CARTA,BRUNA FERNANDES DO CARMO CARVALHO, LUIZCARLOS ISHIDA, YASMIN RODARTE CARVALHO,JANETE DIAS ALMEIDA. UNIVERSIDADE ESTADUALPAULISTA “JÚLIO DE MESQUITA FILHO”.

White boy, 11, complained of pain and extensive swelling inthe jaw plus tooth mobility that evolved over the course of 1 year.Extraoral examination showed significant facial asymmetry withenlargement of the left mandibular body. Intraoral examinationexhibited expansion of the buccal and lingual cortical molar re-gion with severe mobility. Imaging revealed mixed multilocularlesion in the mandible. Incisional biopsy was performed; histo-pathological examination uncovered fragments of unencapsulatedloose tissue that was richly vascularized, with immature irregulartrabecular bone mineralized to varying degrees. Histologicaldiagnosis was benign fibro-osseous lesion. Clinical, radiographic,and histopathological findings lead to the diagnosis of juvenileossifying fibroma. The treatment was a segmental man-dibulectomy and reconstruction with microsurgical fibula flap.The patient presented no local recurrence after 5 months offollow-up.

PE-184 - KAPOSI’S SARCOMA IN AIDS PATIENT: CASEREPORT. ANDRÉ LUCAS D’ALMEIDA LYRIO DOSSANTOS, THAMIRES SILVA SOUZA, DAVI SILVACARVALHO CURI, VINICIUS RABELO TORREGROSSA,ANTÔNIO FERNANDO PEREIRA FALCÃO, PATRICIALEITE RIBEIRO LAMBERTI, VIVIANE ALMEIDASARMENTO. FEDERAL UNIVERSITY OF BAHIA.

Acquired immunodeficiency syndrome (AIDS) is the clinicalmanifestation of advanced infection with human immunodefi-ciency virus (HIV). The progressive depletion of T-lymphocytesby HIV increases the susceptibility to opportunistic infections.The occurrence of some HIV-related malignancies, althoughuncommon, has been reported. Kaposi’s sarcoma is a low-gradelymphatic endothelium neoplasm, associated with humanherpesvirus 8 infection. This tumor has also been diagnosed inHIV-seropositive patients. Patient with AIDS C3 was undergoingantiretroviral treatment. In addition to opportunistic oral in-fections, there was a purplish lesion in the hard palate and oralmucosa. The diagnosis and case management are discussed.

PE-185 - KERATOACANTHOMA OF THE LOWER LIP.EDUARDO PEREIRA GUIMARÃES, FERNANDARAFAELLY DE OLIVEIRA PEDREIRA, PAOLA SINGI,MARINA LARA DE CARLI, ALESSANDRO ANTÔNIOCOSTA PEREIRA, JOÃO ADOLFO COSTA HANEMANN.