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CELLSCALE ǀ 11 – 564 Weber Street N., Waterloo, ON, Canada N2L 5C6 ǀ 519-342-6870 ǀ [email protected] ǀ www.cellscale.com Overview The MicroSquisher has been designed to perform tension and compression testing at low forces. The current IOL test standard (ISO 11979-3:2006) does not address the changing stiffness of IOLs as new materials are being introduced. This study was specifically related to the testing of the force exerted by the IOL haptics in order to hold their position within the eye. The IOL is comprised of a circular lens that is integrated with protruding haptics. The haptics push against the eye to hold the lens in position and alignment so that it can properly function. Haptic Lens Test Procedure and Results Custom 3D-printed fixtures were produced for this application based on the ISO standard. While these fixtures were not sufficiently smooth to for quality test data, they were smooth enough to demonstrate the applicability of the test method. Two different types of IOL specimens were placed in the test fixtures and tested in compression according to the requirements of the standard. The graph at the right shows the force vs. displacement curve for the lenses tested. As expected there was a difference between the 2 lens styles and the force range was such that a conventional load cell would not have sufficient resolution. One cause of the noise in the data can be attributed to the surface roughness of the 3D-printed fixtures. 0 250 500 750 1000 1250 1500 0 200 400 600 800 1000 Force (uN) Displacement (um) Intra-Ocular Lens Testing CellScale Biomaterials Testing is the industry leader for precision biomaterial and mechanobiology test systems. Our products are being used at world-class academic and commercial organizations in over 30 countries around the globe. Our mechanical test systems allow researchers to characterize the mechanical properties of biomaterials. Our mechanobiology technologies provide insights into the response of cells to mechanical stimulation. CellScale’s technologies are improving human health by helping researchers discover the causes of disease, improve medical treatments and devices, and advance regenerative medicine and other basic science research. Visit our website or contact us to learn how our innovative products can help you achieve your research and development goals.

Intra-Ocular Lens Testing - CellScale · 2018. 2. 20. · test standard (ISO 11979-3:2006) does not address the changing stiffness of IOLs as new materials are being introduced. This

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Page 1: Intra-Ocular Lens Testing - CellScale · 2018. 2. 20. · test standard (ISO 11979-3:2006) does not address the changing stiffness of IOLs as new materials are being introduced. This

CELLSCALE ǀ 11 – 564 Weber Street N., Waterloo, ON, Canada N2L 5C6 ǀ 519-342-6870 ǀ [email protected] ǀ www.cellscale.com

Overview

The MicroSquisher has been designed to perform tensionand compression testing at low forces. The current IOLtest standard (ISO 11979-3:2006) does not address thechanging stiffness of IOLs as new materials are beingintroduced. This study was specifically related to thetesting of the force exerted by the IOL haptics in order tohold their position within the eye. The IOL is comprised ofa circular lens that is integrated with protruding haptics.The haptics push against the eye to hold the lens inposition and alignment so that it can properly function.

Haptic

Lens

Test Procedure and Results

Custom 3D-printed fixtures were produced for this applicationbased on the ISO standard. While these fixtures were notsufficiently smooth to for quality test data, they were smoothenough to demonstrate the applicability of the test method.Two different types of IOL specimens were placed in the testfixtures and tested in compression according to therequirements of the standard.

The graph at the right shows the force vs. displacement curvefor the lenses tested. As expected there was a differencebetween the 2 lens styles and the force range was such that aconventional load cell would not have sufficient resolution.One cause of the noise in the data can be attributed to thesurface roughness of the 3D-printed fixtures.

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0 200 400 600 800 1000

Forc

e (

uN

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Displacement (um)

Intra-Ocular Lens Testing

CellScale Biomaterials Testing is the industry leader for precision biomaterial and mechanobiology test systems. Our products are being used at world-class academic and commercial organizations in over 30 countries around the globe.

Our mechanical test systems allow researchers to characterize the mechanical properties of biomaterials. Our mechanobiology technologies provide insights into the response of cells to mechanical stimulation.

CellScale’s technologies are improving human health by helping researchers discover the causes of disease, improve medical treatments and devices, and advance regenerative medicine and other basic science research.

Visit our website or contact us to learn how our innovative products can help you achieve your research and development goals.