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ISSN: 2394-0913 International Journal of Management and Humanities Website: www.ijmh.org Volume-2 Issue-8, January 2017 Volume-2 Issue-8, January 2017 Published by: Blue Eyes Intelligence Engineering and Sciences Publication Pvt. Ltd. Published by: Blue Eyes Intelligence Engineering and Sciences Publication Pvt. Ltd. Exploring Innovation www.ijmh.org H d u n m a t a n n e i t i m e e s g a n a M I n f t o e l r n a a n r t i u o o n J a l E X P L O R I N G I N N O V A T ION

International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

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Page 1: International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

ISSN: 2394-0913

International Journal of

Management and Humanities

Website: www.ijmh.org

Volume-2 Issue-8, January 2017Volume-2 Issue-8, January 2017

Published by: Blue Eyes Intelligence Engineering and Sciences Publication Pvt. Ltd. Published by: Blue Eyes Intelligence Engineering and Sciences Publication Pvt. Ltd.

Exploring Innovation

www.ijmh.org

H d un ma t an ne itim e

e s

ga

na

M I nf to e l rna anr tiu oo nJ al

EXPLORING INNOVA

TION

Page 2: International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

Editor In Chief

Dr. Shiv K Sahu

Ph.D. (CSE), M.Tech. (IT, Honors), B.Tech. (IT)

Director, Blue Eyes Intelligence Engineering & Sciences Publication Pvt. Ltd., Bhopal (M.P.), India

Dr. Shachi Sahu

Ph.D. (Chemistry), M.Sc. (Organic Chemistry)

Additional Director, Blue Eyes Intelligence Engineering & Sciences Publication Pvt. Ltd., Bhopal (M.P.), India

Vice Editor In Chief

Prof.(Dr.) Anuranjan Misra

Professor & Head, Computer Science & Engineering and Information Technology & Engineering, Noida International University,

Noida (U.P.), India

Dr. Sahab Singh

Assistant Professor, Department of Management Studies, Dronacharya Group of Institutions, Knowledge Park-III, Greater Noida

(U.P.), India

Advisory Chair

Dr. C. Saravanan

Associate Professor (System Manager) & Head, Computer Center, NIT, Durgapur, W.B. India

Dr. S. Saravanan

Professor, Department of Electrical and Electronics Engineering, Muthayamal Engineering College, Resipuram, Tamilnadu, India

Dr. Amit Kumar Garg

Professor & Head, Department of Electronics and Communication Engineering, Maharishi Markandeshwar University, Mulllana,

Ambala (Haryana), India

Dr. T.C.Manjunath

Principal & Professor, HKBK College of Engg, Nagawara, Arabic College Road, Bengaluru-560045, Karnataka, India

Dr. P. Dananjayan

Professor, Department of Department of ECE, Pondicherry Engineering College, Pondicherry, India

Technical Chair

Dr. Santosh Kumar Nanda

Professor, Department of Computer Science and Engineering, Eastern Academy of Science and Technology (EAST), Khurda (Orisa),

India

Dr. Hai Shanker Hota

Associate Professor, Department of CSIT, Guru Ghansi Das University, Bilaspur (C.G.), India

Dr. Sunil Kumar Singla

Professor, Department of Electrical and Instrumentation Engineering, Thapar University, Patiala (Punjab), India

Dr. A. K. Verma

Professor, Department of Computer Science and Engineering, Thapar University, Patiala (Punjab), India

Dr. Durgesh Mishra

Chairman, IEEE Computer Society Chapter Bombay Section, Chairman IEEE MP Subsection, Professor & Dean (R&D), Acropolis

Institute of Technology, Indore (M.P.), India

Dr. Xiaoguang Yue

Associate Professor, College of Computer and Information, Southwest Forestry University, Kunming (Yunnan), China

Dr. Veronica Mc Gowan

Associate Professor, Department of Computer and Business Information Systems,Delaware Valley College, Doylestown, PA, Allman

China

Dr. Mohd. Ali Hussain

Professor, Department of Computer Science and Engineering, Sri Sai Madhavi Institute of Science & Technology, Rajahmundry

(A.P.), India

Dr. Mohd. Nazri Ismail

Professor, System and Networking Department, Jalan Sultan Ismail, Kaula Lumpur, MALAYSIA

Page 3: International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

Dr. Sunil Mishra

Associate Professor, Department of Communication Skills (English), Dronacharya College of Engineering, Farrukhnagar, Gurgaon

(Haryana), India

Managing Chair

Mr. Jitendra Kumar Sen

International Journal of Management and Humanities (IJMH), India

Reviewer Chair

Dr. R.Arulmozhiyal

Assoc. Professor, Department of Electronics and Communication Engineering, Adhiparasakthi College of Engineering, Villupuram

(Tamilnadu), India

Dr. R.Harikumar

Professor, Department of Electronics and communication Engineering, Bannari Amman Institute of Technology, Sathyamangalam

(Tamilnadu), India

Dr. Anand Kumar

Professor & Head, Department of MCA, Department of MCA, M.S. Engineering College, Navarathna Agrahara, Sadahalli Post,

Bangalore, Karnataka, India

Dr. Mohamed Rahayem

School of Science and Technology, Karlavägen 16, 691 41 Karlskoga, Sweden

Dr. P.T.V.Bhuvaneswari

Associate Professor, Electronics Engineering, Madras Institute of Technology Anna University, Chennai, India

Dr. Venkat K. Krishnan

Post-Doctoral Research Associate, Electrical and Computer Engineering, 1121 Coover Hall, Iowa State University, Ames, Iowa, USA

50011

Dr. Mangey Ram

Associate Professor, Department of Mathematics, Graphic Era University, Dehradun-248002, India

Dr. Sarika Jain

Assistant Professor, Department of Computer Applications, National Institute of Technology, Kurukshetra, Haryana, India

Dr. Adri Jovin J.J.

Assoc. Professor, Department of Computer Science & Engineering, Sri Guru Institute of Technology, Varathaiyangar Palayam,

Kondayampalayam, Coimbatore (Tamil Nadu), India

Dr. V.Kumar Chinnaiyan

Professor & Head, Department of Electrical and Electronics, Jansons Institute of Technology, Caimbatore (Tamil Nadu), India

Dr. T. Pearson

Professor, Department of ECE, SMK Fomra Institute of Technology, Anna Nagar West, Chennai, India

Dr. Indu Verma

Professor, Department of Physics, University of Lucknow (U.P.), India

Dr. Pravin P Patil

Assoc. Professor, Department of Mechanical Engineering, Graphic Era University, Dehradun-248002, India

Dr. Surendra Yadav

Professor, Department of Computer science and Engineering, Dreen Avenue, Khatipura Road, Jaipur, India

Dr. K. Sivakumar

Assoc. Professor, Department of Computer Applications, SNMV College of Arts & Science, Maruthasalam Nagar, Sulur, Coimbatore

Dr. Lazar Stosic

College for Professional Studies Educators, Aleksinac, Serbia, Europe

Dr. Ashu Gupta

Assoc. Professor, Department of Computer Applications, Apeejay Institute of Management Technical Campus, Jalandhar, Punjab,

India

Page 4: International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

Dr. T.Logeswari

Associate Professor, Department of MCA, Dr.N.G.P. – Kalapatti Road Coimbatore - 641048 India

Dr. Nurul Fadly Habidin

Department of Management, Faculty of Management and Economics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim,

Perak

Dr. S.Manikandan

Department of ECE, Dean,VKS College of Engineering and Technology, Karur,Tamilnadu, India

Dr. S.Sasikumar

Department of ECE, Jayaram College of Engineering and Technology, India

Dr. Mojtaba Moradi

Assoc. Professor, Department of Statistics, Faculty of Mathematical Sciences, University of Guilan, Rasht, Iran

Dr. Neeraj Kumar

Assoc. Professor, Department of Applied Sciences & Humanities, IIMT Engineering.College, Meerut (U.P.), India

Dr. T.V.Suryanarayana

Assoc. Professor, Department of ECM, K L University, Green Fields,Vaddeswaram, Guntur District, A.P., India

Page 5: International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

S.

No

Volume-2 Issue-8, January 2017, ISSN: 2394-0913 (Online) Published By: Blue Eyes Intelligence Engineering & Sciences Publication Pvt. Ltd.

Page

No.

1.

Authors: R. Sarumathi, Vidyadhar Reddy Aileni, Mohammed AbbasAli

Paper Title: Employee’s Quality of Work life in Pharmaceutical Industry – A Factor Analysis

Abstract: This study aims at “Quality of Work Life” with collected perceptions on several occupational cultures

relating to human factors, to create prominent advancements by considering the effective responses and it will

explore the relationship of different parameters among the quality of work life of the employees who are working in

pharmaceutical industry in Hyderabad. The sample was taken from three major organisations that plays vital role in

the industry by using proportionate sampling method. The pre constructed and close ended questionnaires were

distributed among the respondents for the data collection. The collected data was analysed with frequency

distribution, Pearson’s correlation analysis, and student t-test and then found that most of the quality of work life

factors are inter-related.

Keywords: Fair compensation, health and safety, job satisfaction, pharmaceutical industry, Quality of work life,

work and life balance.

References: 1. Adel Salavati, Keyhan Maghsoudi and Kaveh Hasani, (2013) “Relationship between Quality of Work Life and the Productivity of

Manpower”, Management and Administrative Sciences Review, Volume: 2; Issue 3; 243-253. 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL) and

Organizational Commitment of Melli Bank Staff in West Domain of Mazandaran in 2009-2010”, Australian Journal of Basic and Applied

Sciences, 5(8); 682-687. 3. Chandranshu S, (2012) “Factors affecting quality of work-life Empirical Evidence From Indian Organization” Australian Journal of

Business and Management Research, Volume:1; No.11; 31-40. 4. Delamotte Y and Walker KF, (1974) "Humanization of Work and the Quality of Working Life - Trends and Issues”, International Institute

for Labour Studies Bulletin, Volume: 11, 3-14.

5. Deloitte and Touche USA, (2007) “Leadership counts: Ethics and workplace survey results. USA” Deloitte Development LLP. 6. Efraty DS, Joseph M, (1990) “The effects of quality of working life (QWL) on employee behavioral responses” Social Indicators Research,

22(1).

7. Emadzadeh, Kazem M, Khorasani M and Nematizadeh F, (2012) “Assessing the quality of work life of primary school teachers in Isfahan city” Interdisciplinary Journal of contemporary Research in Business, 3(9); 438-448.

8. Glasier E (1976) “State of the Art, Questions about Quality of work life” Personnel.

9. Hassan N , Maamor H, Razak AN, and Freziamella L, (2014) “The Effect of Quality of Work Life (QWL) Programs on Quality of Life (QOL) among Employees at Multinational Companies in Malaysia”, Procedia - Social and Behavioral Sciences, Volume: 112; 24–34.

10. Jain Bindu and Swami Yashika (2014) Quality of Work Life with Special Reference to Academic Sector, Research Journal of Management

Sciences, Vol. 3(1), 14-17, January. 11. Katzell, R.A., Yankelovich, D., Fein M., Ornate, D.A. & Nash,A. (1975), Work Productivity and Job Satisfaction, The Psychological

Corporation, New York.

12. Md. Zohurul Islam, and Sununta Siengthai (2009) Quality of work life and organizational performance: Empirical evidence from Dhaka Export Processing Zone. The paper presented in the Conference on ‘Regulating for Decent Work, has been held at the International Labour

Office, Geneva during July 8-10.

13. Nayeri, Nahid Dehghan, Salehi, Tahmineh and Noghabi Ahmad Ali Asadi (2011) Quality of work life and productivity among Iranian nurses, Contemporary Nurse, 39(1), 106–118.

14. Raduan Che Rose, LooSee Beh, Jegak Uli and Khairuddin Idris, 2006: Quality Of Work Life: Implications Of Career Dimensions,

University of Malaya, Malaysia. 15. S. Jayaraman (2014) A Study on Quality of Work Life of Paper & Pulp Mill Employees in Dindigul District, Tamilnadu, India, Asian

Journal of Research in Business Economics and Management Vol. 4, No. 2, February, pp. 187-201.

16. Sameer Ahmad Shalla ,Dr Asif Iqbal Fazili (2013) Quality Of Work Life And Employee Job Satisfaction- A Dimensional Analysis , Journal Of Research In Management & Technology Special Issue Proceedings Of National Conference On Trends In Management, Engineering

Technology)

17. Sandrick K. Putting the emphasis on employees. Trustee 2003;56(1):6-10, 1. 18. Seyed Mohammad Moghimi, Masoumeh Kazemi, Saied Sammie (2013) Iranian Journal of Management Studies (IJMS) Vol.6, No.1,

January, pp: 119-145

19. Walton, R. (1973), Quality of work life Indicators- Prospects and Problems- A Portugal Measuring the Quality of working life, pp-57-70.

1-6

2.

Authors: Mahajan P. T., Golahit S. B.

Paper Title: Downcast Enrollments: A Desperate Need of Holistic Marketing for Technical Education

Abstract: Purpose: Modern history has shown that only those countries, which could acquire capability to develop

and apply science and technology, have found great success to grow their wealth and improve living conditions of

their population. Technical education in India contributes a major share to the overall education system and plays a

vital role in the social and economic development of the nation. There is a rapid growth of technical education in last

decade in terms of the no. of institutes and intake capacity in India, however, institutes failed to attract enrollments

which observed noticeable gap in between the actual no. of enrollments and intake capacity. In the year 2015-16,

46% of seats were vacant in Technical Education in India. The purpose of this paper is to highlight holistic marketing

approach with promotion mix on diversified enrollments to motivate enrollments in selecting institute of Technical

education. Design methodology: A qualitative research by a survey (through a structured questionnaire) of students

who are presently enrolled (Current-students) and those who have completed their study (Post-students) belonging to

the institutes offering Technical Education situated in Khandesh region of India and affiliated to the North

Maharashtra University, Jalgaon. Findings: The study found that diversified characteristics of enrollments are related

with the promotion mix of TE institute in selection of technical educational institute. This study investigates the

usefulness of school visits, institution publications, websites, campus visits, word-of-mouth (friends, alumni, school

teachers), advertisements (radio, television, magazines) and events on campus, as a tool of holistic marketing and

promotion mix. Social Networking and Institute’s Website are the emerging tools of promotion mix in selection TE

7-14

Page 6: International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

institute in Khandesh Region. Research limitations: The survey is delimited to the enrollments of technical education

belonging to North Maharashtra University, Jalgaon and located in Khandesh region of India. Practical implications:

This article provides relationship of promotion mix & diversified characteristics of enrollments on institutional

choices. Different communication strategies of promotion mix can be used based on diversified characteristics

(segmentation) of enrollments to attract enrollments. The paper also represents new form of promotion mix of

educational service that affects students’ decision in selecting their technical educational institute.

Keywords: Enrollments, Segmentation, Promotion Mix, Holistic Marketing, Technical Education

References: 1. Data Source: Government of India (website:http://mhrd.gov.in/statist). Educational Statistics at a Glance (2016). Published By: Government

of India, Ministry of Human Resource Development, New Delhi. 2. Kasturirangan, K., (2004). Technical education and national development. University News, 42(31), Aug 2004. 18-21.

3. Dasgupta P. R., Secretary, Urban Affairs and Employment, Government of India, Source: http://pib.nic.in/feature/fe0199/f0501991.html

4. Smith L, Tamer S., (1984). Marketing Planning for Colleges & Universities. Long Range Planning, 17(6), 104-117, Retrieved October 8, 2007.

5. Kotler, Philip (1972), A Generic Concept of Marketing. Journal of Marketing. 36 (April), 46-54.

6. Kotler, Philip and Patrick E. Murphy (1981), Strategic Planning for Higher Education. Journal of Higher Education, 52 (September-October), 470-489.

7. Beverland, M., Napoli, J., and Lindgreen, A. (2007). Industrial global brand leadership.

8. Darrell Norman Bureell and Brain C., Grizzell (2008). Competitive Marketing and Planning Strategy in Higher Education. Academic Leadership: Online Journal, Vol. 6 No. 1

9. Levine, A. (2000). The future of colleges: 9 inevitable Changes. Chronicle of Higher Education, October 27 2000.

10. Johnson Wayne and Jones Russel. Declining Interest in Engineering Studies at a Time of Increased Business Need. Book: Universities and Business: partnering for knowledge society, part V, Chapter 20, p-233-240

11. Sathivel, P.B., Rajendran, G. & Raju, R. (2005). TQM Implementation and students’ satisfaction of academic performance. The TQM

Magazine, Vol.17 No. 6, pp. 573-89. 12. Kelley, H. & Mahady, T. 2003. Marketing for non-profit organizations – Introduction. [Online]. Available from:

http://www.charityvillage.com/cv/research/rfmk48.html [Downloaded: 12-05-2006].

13. Bok, 2003; Kirp, 2003; Zemsky, Wegner, and Massy, 2005. Strategic Leadership: Integrating Strategy and Leadership in Colleges and Universities. Published by: Americal Council on Education, 2007

14. Kotler, P. & Fox, K. 1995. Strategic marketing for educational institutions. Englewood Cliffs, New Jersey, USA: Prentice Hall.

15. Kittle, B. 2000. Institutional advertising in higher education. Journal of Marketing for Higher Education, 9(4). 16. Laurer, L.D. 2006. Advancing higher education in uncertain times. [Online]. Available from: http://www2.university [Downloaded: 2006-12-

6].

17. Cann, C.W., & George, M.A. (2003). Key elements of a successful drive toward marketing strategy making. Journal of Marketing for Higher Education, 13(1&2), 1–15

18. Howe, N. & Strauss, W. (2000). Millennials rising: the next great generation. (New York, NY, Vintage Books). 19. Keller Kevine and Kotler Philip. Holistic Marketing - A broad, Integrated Prospective to Marketing Management. Chapter 30 of Does

Marketing Need Reform? Fresh Perspectives on the Future; 2006; p-300

20. Lamb, C.W., Hair, J.F., McDaniel, C., Boshoff, C. & Terblanche, N.S. 2004. Marketing management. 2nd ed. South Africa, Cape Town: Oxford University Press.

21. Ahmed, P. K., Rafiq, M., and Saad, N. M. (2003). Internal Marketing and the Mediating role of Organizational Competencies. European

Journal of Marketing, 37, 1221-1278. 22. Kitchen, P., & Burgmann, I. (2015). Integrated marketing communications: Making it work at a strategic level. Journal of Business Strategy.

36: 34–39. doi:10.1108/JBS-05-2014-0052

23. Belch, G. E., & Belch, M. A. (2004). Advertising and promotion: An integrated Marketing communications perspective. (6th ed.). New York: McGraw-Hill/Irwin.

24. Bansal, H. S., Mendelson, M. B., Sharma, B. (2001). The Impact of Internal Marketing Activities on External Marketing Outcomes. Journal

of Quality Management, 6, 61-76. 25. Machado, R. & Cassim, S. (2002). Marketing for entrepreneurs. 2nd ed.

26. Strydom, J., Jooste, C. & Cant, M. 2000. Marketing management. 4th ed. Cape Town: Juta.

27. Jones, M. (2002). The effectiveness of marketing communication strategies employed by universities and Technikons in the Cape Peninsula with specific reference to career exhibitions and open days in attracting first year students. Unpublished Masters thesis. Cape Town:

University of Cape Town.

28. Kotler, P. & Armstrong, G. (2001). Principles of marketing. 9th ed. Englewood Cliffs, New Jersey, USA: Prentice Hall 29. Lagae, Wim (2005). Sports Sponsorship and Marketing Communication: A European Perspective. Harlow: FT Prentice Hall cop. 2005

30. Jobber, David (2007). Principles and Practice of Marketing. 5th ed. McGraw-Hill 2007.

31. Chester, P.A. (2005). EDU Internet strategies to market higher education organizations. Press release (EDU–IS). 32. Du Plessis, P.J. & Rousseau, G.G. (2005). Buyer behavior: A multi-cultural approach. 3rd ed. Cape Town: Oxford

33. Seymour, L. (2000). Giving the Web the new college try: Students online surf to sample life on campus. The Washington Post. 28 March: 11.

34. Barnes, N. and Lescault, A. Social Media Adoption Soars as Higher‐Ed Experiments and Reevaluates Its Use of New Communications

Tools. U‐Mass Dartmouth Center for Marketing Research, 2012. p. 5‐10.

35. Morgan, R. M. & Hunt, S. D. (1994, July). The commitment-trust theory of relationship marketing. Journal of Marketing, 58, 20–38.

36. Internet Source: Academic Ranking of World Universities. http://www.shanghairanking.com/ARWU2016.html

3.

Authors: N. Anitha

Paper Title: Entrepreneurial Potential, Intention and the Influential Factors for Entrepreneurship Among the

Women Students of Coimbatore City

Abstract: Women are natural entrepreneurs who are capable of managing multiple tasks at ease but most of them do

not realize their potential. In spite of the increasing recognition of entrepreneurship as a source of job creation,

regional development, and economic dynamism in a rapidly globalizing world, there has been no notable change in

numbers and most of the cases unemployed women only turn up to entrepreneurship. Universities and educational

institutions insisting various courses and training programs towards the development of entrepreneurship and

creating the entrepreneurial culture and eco system in the campuses. Most of the students have the potential of

becoming an entrepreneur and they do not have the intention to become an entrepreneur sometimes they are equipped

with the potential as well as intention but they are not getting motivated to become an entrepreneur. So the study was

intended to know among the selected population that how many students are having the potential and how many of

the potential students has the intention even though having those potential as well as intention how many of them are

15-21

Page 7: International Journal of Management and Humanities€¦ · 2. Asgari, Mohammad H, and Dadashi and Mohammad A, (2011) “Determining the Relationship between Quality of Work Life (QWL)

really motivated to become an entrepreneur and also to study the various factor which is stopping them not to

become an entrepreneur. So the questionnaire was distributed among the students and the responses were collected

and analyzed using the simple percentage analysis tool and the results were presented. The suggestions will help the

policy makers and educationalist to develop a strategy for promoting entrepreneurial culture among the students.

Keywords: Entrepreneurial Intention, Entrepreneurial Potential, Entrepreneurial Culture, Entrepreneurial Eco

System

References: 1. Tubbs & Ekeberg (1991) The Role of Intentions in Work Motivation: Implications for Goal-Setting Theory and Research, The Academy of

Management Review Vol. 16, No. 1 (Jan., 1991), pp. 180-199 Published by: Academy of Management URL: http://www.jstor.org/stable/258611.

2. Source - (Ajzen, 1991) Organsiational behaviour and human decision process, the thory of planned behaviour, volume 50 Issue 2, 179 – 211

3. (Goldberg, 1993) The structure of phenotypic personality traits, American Psychologist Association, vol 48 ,26-34. 4. Carter, Gartner, Shaver & Gatewood (2003) Journal of Business Venturing, 2003, vol. 18, issue 1, pages 13-39.

5. Wang & Wong (2004) Entrepreneurial interest of university students, Technovation Journal, volume 24, issue 2, 163-172, Elsevier.

6. Zhao, Seibert, and Hills (2005), the mediating role of self-efficacy in the development of entrepreneurial intentions, the journal of psychology, vol 6 (265-272).

7. Souitaris et al. 2007). Do entrepreneurship programmes raise entrepreneurial intention of science and engineering students? The effect of

learning, inspiration and response, Journal of Business Venturing, volume 22.566-591, Elsevier.

8. lalit sharma (2014 ), Effect of individual factors on youth entrepreneurship – a study of Uttarakhand state, India , Journal of Global

Entrepreneurship Research. http://www.journal-jger.com/content/2/1/3

9. Bird (2015) Entrepreneurial Knowledge, personal attitude, entrepreneurship intentions among the university students, Problems and Perspectives in Management, Volume 13, Issue 1, 2015.

4.

Authors: Ehsan Khodajou, Ali Nazemi

Paper Title: The Study of the Recurrent Sequence of CAG in Three Generations of an Iranian Family Suffering

from Huntington Disease via PCR-Sequencing

Abstract: Background: Huntington’s disease (HD) is the most common neurodegenerative one having the dominant

autosomal inheritance which is being characterized by the excessive uncontrolled motor movements and the deficits

in the emotional and cognitive functions. The mutation responsible for Huntington disease leads polyglutamine

protein to be distributed in Huntington protein which carries more toxic functions towards Huntington protein. The

aim of the study is to design a PCR system to diagnose Huntington disease which can detect the genotype of the

disease.

Keywords: Huntington, PCR, CAG sequence

References: 1. Bonelli RM, Wenning GK.(2006). Pharmacological management of Huntington’s disease: an evidence-based review. Curr Pharm Des; 12:

2701-2720.

2. Bozza A, Malagù S, Calzolari E, Novelletto A, Pavoni M, del Senno L.(1995). Expansion of a (CAG)n repeat region in a sporadic case of HD. Acta Neurol Scand; 92: 132-134.

3. Djoussé L, Knowlton B, Hayden M, Almqvist EW, Brinkman R, Ross C, et al . ( 2003). Interaction of normal and expanded CAG repeat

sizes influences age at onset of Huntington disease. Am J Med Genet A; 119: 279-282. 4. Hayden MR, Bruyn G.(1981) Huntington's Chorea. New York: Springer Verlag; 1-13.

5. Zuhlke C, Riess O, Schroder K, et al.(1993) Expansion of the (CAG)n repeat causing Huntington's disease in 352 patients of German origin.

Hum Mol Genet; 2(9): 1467-9. 6. Mazdeh M, Pour-Jafari H, Ghaleiha A, Pour-Jafari B (2008) A survey of (CAG)n repeats causing juvenile Huntington disease in an Iranian

family with 4 affected members. Neurosciences; 14 (3): 273-276

7. Nance MA, Myers RH. (2001). Juvenile onset Huntington’s disease—Clinical and research perspectives. Ment Retard Dev Disabil Res Rev; 7: 153–157.

8. Novelletto A, Persichetti F, Sabbadini G, et al.(1994). Analysis of the trinucleotide repeat expansion in Italian families affected with

Huntington disease. Hum Mol Genet; 3(1): 93-8. 9. Walker FO.(2007). Huntington’s disease. Lancet; 369: 218-228.

10. Wojaczyńska-Stanek K, Adamek D, Marszał E, HoffanZacharska D.(2006). Huntington disease in a 9-year-old boy: clinical course and

neuropathology examination. J Child Neurol; 21: 1068-1073.

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