Innovative. Flexible. Efficient. - DKSH...like mixers, reactors and heat exchangers to be conveniently mounted and re-arranged at will, for maximised flexibility. If you think it resem-bles

Produc t Ca ta logue

Innovative. Flexible. Efficient.The fascinating world of microreaction technology.

Microreaction technology 04

One company, three product groupings, which adds up to:

ingeniously numberless options. 08

The Modular MicroReaction System (MMRS): 10

Mixers 13

Reactors 16

Heat exchangers 22

Sensors & actuators 24

Links & connections 28

Clamping components 30

Automation system 33

Lonza FlowPlate™ MicroReactors 34

Miprowa® high-performance reactors and heat exchangers 38

Special models 42

Services & support 44

Index 46

Microreaction technologyBecause your process deserves the best.

It shrinks laboratory systems to the size of a briefcase. It renders your processes faster, more efficient, more reliable. It has long since taken up residence in the laboratories of universities and research institutions, and it’s the new star in the chemical and pharmaceutical industries: microreaction technology ranks among the most innovative around, offering fit-for-purpose excellence in a multitude of different applications.

HigHly compet it iveAs a company operating in the chemical or pharmaceutical industry, in a business environment of fierce global competition, your chosen market poses an abundance of challenges: increased pressure on pricing, a fast time-to-market and a never-ending flow of new products – these all demand intelligent solutions. Microreaction technology can provide the assistance you need, enabling you to easily upscale from the laboratory to mass production – using miniaturised intelligence.

Uncompromisingly goodMicroreaction technology is high-tech excellence in a minimised space, and yet the micro- and milli-structured components are more effective in operation than conventional systems. Here are 10 good reasons that speak for themselves:

excellent heat transfer

high mixing speed

simple, reliable scale-up

defined residence times

enhanced operational safety

ultra-flexible, conveniently mobile

simple automation

major potential for process intensification

quick and easy product change

higher yield and selectivity

e xcept iona lly versat ileWith so many advantages, it’s hardly surprising that systems featuring micro-structured components are gaining steadily in popularity, and being adopted for progressively more application categories. They are in routine use at leading companies in the chemical industry, plus of course in the pharmaceutical sector, and this trend is steadily gaining momentum in the consumer goods, food and beverage industries as well. We’ve provided an overview of this sheer diversity on page 6.

FUtUre-responsiveSuccessful products nowadays have to be cost-efficient, flexible and sustainable – and this will be even truer in the future. Microreaction technology plays a key role here for production processes whose innovative ingenuity is equalled only by their persuasive cost-efficiency. And Ehrfeld Mikrotechnik BTS offers you everything you need for this purpose: from the laboratory to the production line. We have summarised in this catalogue the entire spectrum of our products and services.

Welcome to the fascinating world of microreaction technology.

0504

Microreaction technologyUp and running almost everywhere.

excellent heat transfer

metal organic reactions

(total ) evaporation

heterogeneous catalysis

highly exothermic reactions

high mixing speed

mass transfer limited

reactions

dispersion

emulsification

particle precipitation

mixing sensitive reactions

intelligent apparatus design

effective scale-up

mobile & flexible plants

photochemistry

cGMP synthesis / API

synthesis

continuous processing

frequent product change

instable intermediates

PAT relevant processes

locally production on-demand

advantageous property

selected application

0706

One company, three product groupings, which adds up to: ingeniously numberless options.

Ehrfeld Mikrotechnik BTS is one of the innovation leaders when it comes to microreaction technology. Our portfolio consists of three product groupings:

the Modular MicroReaction System, MMRS for short

Lonza FlowPlate™ MicroReactors and

high-performance reactors and heat exchangers based on our Miprowa® technology

For our customers, this opens up an infinite number of options for applicational versatility. More – as a subsidiary of Bayer Technology Services, we offer you an attractive combination: the flexible rapid-response capabilities of an innovative technology specialist plus the comprehensively competent background of a prestigious globally operating corporation.

customers choose us as their vendor because we

develop up-to-the-future and at the same time cost-efficient solutions for a multitude of specific applications for microreaction technology

offer leading-edge quality in terms of technology, service support and consultancy

employ flexible and highly qualified experts

are committed to a stringent standard of quality in creating and design-enhancing our modules and processes

possess maximally fit-for-purpose infrastructure with laboratories and workshops

rigorously pursue customer focus in our after-sales service operations

provide professional management of your international projects as well as working closely together with competent partners

belong to a networked alliance of partners in the industrial sector and at research institutions

are able to offer you holistically conceived solutions along a system’s entire life-cycle

The following symbols will guide you through the world of our innovative products:

mmrs

Mixers

Reactors

Heat exchangers

Sensors & actuators

Links & connections

Clamping components

lonza Flowplate™

miprowa®

scalability

mmrs

miprowa®

lonza Flowplate™

0908

The Modular MicroReaction System:A toolkit for innovative versatility.

There’s nothing in the world to equal our Modular MicroReaction System, or MMRS for short: laboratory equipment in modularised design. It speeds up the development of new processes, and simpli-fies process intensification while also maximising flexibility. With the MMRS, we offer companies optimum preconditions for pole position in the international competitive environment.

Fle x ibleThe salient feature of our system is its modularised construction. More than 60 different microreaction modules can be quickly and easily combined with each other, so as to create a customised system meeting the particular job profile involved. The operating parameters, conversely, have been standardised:

temperature range: - 20 – 200 °C, - 100 – 600 °C for special applications

operating pressure: up to 100 bar, higher figures on demand

flow rate: 0.01 – 30 L/h, depending on the module concerned

materials: stainless steel, Hastelloy® and others on request

The MMRS is mounted on a base plate available in the following sizes: A5, A4, A3 and A2. It is divided up into a square raster with a length of 25 x 25 millimetres per cell, enabling all our micro-components, like mixers, reactors and heat exchangers to be conveniently mounted and re-arranged at will, for maximised flexibility. If you think it resem-bles a plug-in system, you are quite right: the Modular MicroReaction System is just as simple – and its construction, too. Moreover, our components are very sturdy and can be easily dismantled, so that even minuscule channels can be cleaned without any problems. You’d like some more extras? No problem. The MMRS is available in special sizes, and can if required be fitted with a base plate heater. On a long-term view as well, the built-in flexibility comes up trumps: because every new supplementary module can be easily integrated, and even years later can be adapted on the platform. Since often only one module is needed for pilot trials, we offer for this purpose an equally flexible solution: many MMRS modules can be used as stand-alone units with a standard connection and without a base plate.

saFeOur micro-mixers, micro-reactors and micro-heat-exchangers have proved their worth wherever processes with sophisticated reactions are being run: in the case of severely exothermic reactions, for instance, or where substance transport limits the reaction speed, but also when using toxic and potentially explosive substances, they are an excellent choice. With these components, reactions can be performed under precise conditions and simply monitored, while the potential hazards are reduced, because the reaction volume is smaller, thus providing optimum preconditions for safe and dependable operation of your system.

eFFic ientThe Modular MicroReaction System scores highly in comparison to conventional designs, not only in terms of its surface-to-volume ratio. Its finely structured modules and its continuous operating mode open up an abundance of further potential as well: as a user, you benefit from significantly accelerated development of new processes and products, in addition to optimised use of energy and starting materials. And all this on a footprint that’s no larger than a sheet of notepaper – for miniaturised all-round efficacy.

aUtomatedWe adopt new approaches to laboratory automation: instead of individual components, the LabBox® integrates numerous automation functions in a single compact device – for unlimited options in your laboratory. External devices for instrumentation and control, plus the conventional control cubicle, are thus rendered superfluous. LabBox® is flexible, effective in operation, and very user-friendly, since the integrated module library ensures simple and intuitive use (page 33).

sca l ableIn the shape of the MMRS, we provide you with an intelligent set of laboratory equipment with which you can develop and optimise new products and processes. Our capabilities also cover all the further phases: transfer to pilot operations, and later to production scale. For this purpose, we offer the following specialised product groupings: Lonza FlowPlate™ (page 34) and Miprowa® (page 38), but numerous MMRS modules can also be upscaled for larger flow rates, such as the LH 1000 (page 42) or the Valve Mixer 300 (page 42).

These scalable MMRS modules are designated in the catalogue by the symbol .

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The construction of the Modular MicroReaction System could hardly be simpler

The modules are mounted on the base plate. The modules’ own bottom plates are fitted with guide elements, which engage in the grooves of the base plate raster so as to align the modules involved. In addition, the bottom plates are made of PEEK in order to thermally decouple the modules from the base plate. This is shown in diagram a, as exemplified by a random row of five modules. For reasons of clarity, the base plate is not shown in the diagrams.

At both ends of the module row, clamping modules are screwed into the base plate by manually turning the wheel at the top (diagram a).

A sealing plate is inserted at every gap between two modules (diagram a).

Beginning with the longest module row, all rows are clamped. For this purpose, the wheels of the clamping modules are turned further by means of a hexagon socket key (diagram b).

This causes a ram to move out of the clamping module towards the modules in the row, thus pressing together the row of modules and the sealing plates (diagram c).

The connections of the inlet modules are linked up to dosing pumps and the connections of the outlet modules to product vessels by pipes or hoses. The inlets and outlets of the heat exchangers are connected to thermostats or cryostats.

Finally, electric heaters, valves, sensors and other actuators are linked up to the instrumentation and control unit by cables.

a

b

c

mixerCascade Mixer

06, 10, 15Slit-Plate Mixer

LH 2, LH 25 Comb-Type Mixer Valve Mixer 30Microjet Mixer

Art.-No. 0216 0113, 0109 0101 0111 0123

Volume flows06: from 0.1 L/h,10: from 0.3 L/h,15: from 0.9 L/h

0.1 – 6 L/h,3 – 120 L/h

from 0.3 L/h 3 – 30 L/h

with 50 µm-nozzle: 0.3 – 2 L/h

with 100 µm-nozzle: 1 – 7 L/h

Scalable* Development stageLH 1000 up to 3,000 L/h

see Slit-Plate MixerValve Mixer 300 up to 300 L/h

up to 600 L/h

Mixing of liquids ✓ ✓ ✓ ✓ ✓

Emulsification / Dispersion ✓ ✓ ✓ ✓ ✓

Mixing of liquids and gases – ✓ ✓ – ✓

Particle precipitation – – – ✓ ✓

Suspensions ✓ – – – –

MixersWhen you need the right type.

Mixing ranks among the most important basic operations in the process industry. Depending on the task involved, you require the appropriate type of mixer. And we are sure to have precisely the one you need. No matter which of our micromixers you opt for – all of them excel in terms of persuasive product advantages:

reassuringly sturdy construction

field-proven and dependable in operation

configuration flexibly matched to the specific mixing job involved

uncomplicated cleaning, since our micromixers can be completely dismantled

small passive volume

Our high-quality mixers are available in stainless steel or Hastelloy®, or in other materials on request.

The applicational recommendations specified above are guideline values, and may differ in individual cases. For recommendations relating to a particular application, please get in touch with our technical service department.

* Technical solution available at Ehrfeld Mikrotechnik BTS.

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LH 2

LH 25

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comb-type mixerA4, HCMixing principle: Multi-lamination

Art.-No. 0101-3

slit-plate mixer lH 2, lH 25A4, HCMixing principle: Multi-lamination

model LH 2: Art.-No. 0113-3 model LH 25: Art.-No. 0109-4

cascade mixer 06, 10, 15A4, HCMixing principle: Split and recombine

Art.-No. 0216-3

large channel dimensions – available in the following channel widths: 0.6 mm, 1.0 mm and 1.5 mm

sturdily resistant to blockages

fluidically temperature-controlled

mixing and aperture plate are replaceable

mixing slits available in the following nominal diameters: 25/25 µm, 50/50 µm, 85/25 µm, 100/25 µm,

150/25 µm, 150/50 µm, 300/100 µm, 300/300 µm

aperture slits available in the following nominal diameters: 25 µm, 50 µm, 100 µm, 300 µm

model LH 25 available with integrated Pt100

for liquid-liquid and gas-liquid mixing, such as emulsions

model LH 2 for laboratory applications: volume flows from 0.1 – 6 L/h

model LH 25 dimensioned for the pilot scale, and also optimally suited for production operations – specialty chemicals and

pharmaceuticals: volume flows from 3 – 120 L/h

for volume flows of up to 3,000 L/h, we offer the LH 1000 model (page 42)

for mixing jobs with wide flow-rate and viscosity ranges, such as mixing melts and suspensions,

but also liquid-liquid mixtures and emulsions

fluid flows are split several times and brought together again in an offset configuration

volume flows:

model 06: from 0.1 L/h, model 10: from 0.3 L/h, model 15: from 0.9 L/h

with three different replaceable aperture plates (nominal diameters: 50, 100 and 200 µm) included in the delivery package

for liquid-liquid and gas-liquid mixtures, e.g. for emulsions

volume flows: from 0.3 L/h

microjet mixerHCMixing principle: Impact jet

Art.-No. 0123-2

valve mixer 30A4, HCMixing principle: Multi-lamination, impact jet

Art.-No. 0111-2

mixing plates with different nominal slit diameters between 105 and 400 µm available

micro-nozzles for creating jets, made of sapphire

available in two nominal diameters: 50 and 100 µm

special mixing principle: two fine jets of liquid strike each other at high speed at an angle of

180 degrees and are removed by a gas flow

extremely fast mixing without causing any deposits or blockages

optimum conditions for producing catalyst suspensions, for example

for volume flows of 0.3 to 2 L/h or 1 to 7 L/h

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innovative mixer type with one special feature:

the non-return valve can almost totally prevent any

back-flow of the mixture

micro-structures remain free from particle deposits,

which in other types of micromixer lead to blockages

suitable for continuous precipitation reactions, e.g. for producing

nano-particles, catalyst particles or colour pigments in suspension

for volume flows of up to 30 L/h

for volume flows of up to 300 L/h, we offer the

valve mixer 300 (page 42)

reactor CryoReactorLonza

FlowPlate™ LabMeander

Reactor 2, 11Sandwich Reactor Miprowa® Lab Reactor 100

Residence reactors

Art.-No. 0202 1701 0211 0213 0224 0219

Process volume

2.4 mL (total),1.7 mL (cooled)

depending on process plate

2 mL,11 mL

30 mL30 mL (depending

on inserts)110 mL

Max. pressure at 25 °C

100 bar 16 bar 20 bar 20 bar 30 bar 100 bar

Temperature range

- 80 – 100 °C- 20 – 120 °C, (- 60 – 200 °C)

- 20 – 200 °C - 20 – 200 °C - 20 – 200 °C - 10 – 200 °C

Type of temperature control

fluidic fluidic fluidic fluidic fluidic fluidic

Dismantable partial ✓ ✓ ✓ ✓ ✓

Continuous mixing

– variable – ✓ ✓ ✓

Scalable* –Lonza FlowPlate™

A6, A5, A4✓ Miprowa® Miprowa® Reactor 450

on request

Applications

low-temperature reactions,

single-phase liquid reactions

single- and multi-phase

liquid-liquid as well as gas-liquid

reactions

single-phase liquid reactions, reactions with suspensions



reactions



reactions


liquid reactions, reactions with suspensions

ReactorsFor continuous quality.

Microreactors are operated in continuous mode. The reaction mixture flows steadily through the reaction volume – producing significant benefits compared to a classical batch mode: these include higher product quality, better process monitoring and enhanced reliability. This all adds up to more cost-efficiency and reduced environmental impact, thanks to optimised use of energy, raw materials and solvents.

* Technical solution at Ehrfeld Mikrotechnik BTS available.

reactor Photo-ReactorCartridge Reactor

200Cartridge Reactor

240 HT Reactor Unit**

Fixed-Bed Meander Reactor

Photochemistry Heterogeneous catalysis

Art.-No. 0226 0201 0221 0227 0222

Process volume

0.04 – 0.16 mL (depending on variable

layer thickness)0.7 mL 5 mL up to 5 mL 25 mL

Max. pressure at 25 °C

2.8 bar 30 bar 100 bar 100 bar 35 bar

Temperature range

+ 15 – 50 °C up to 200 °C up to 240 °C up to 600 °C - 20 – 200 °C


fluidic electrical electrical electrical electrical

Dismantable ✓ partial partial partial ✓

Continuous mixing

– – – – –

Scalable* Photo-Reactor XL Cartridge Reactor 240 – – –

ApplicationsPhotochemistry with

fluid mediaHeterogeneous

catalysis in a fixed bedHeterogeneous



catalysis in a fixed bed

The applicational recommendations specified above are guideline values, and may differ in individual cases. For recommendations relating to a particular application, please get in touch with our technical service department.

* Technical solution at Ehrfeld Mikrotechnik BTS available. ** Prototype is currently in the test phase.

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meander reactors 2, 11A4, HC

Art.-No. 0211-2

lonza Flowplate™ labHC

Art.-No. 1701-2

cryoreactorA4, HC

Art.-No. 0202-4

enhanced flexibility thanks to replaceable micro-structured

process plates with up to ten inlets and outlets along the

process section (page 36)

integrated and fluidically temperature-controlled mixing

and residence sections

visual monitoring of the flow processes along the entire

channel through a sight glass

process temperature: - 20 – 120 °C, - 60 – 200 °C (on request)

pressure up to 16 bar (at 25 °C)

can be completely dismantled

process temperature: - 80 – 100 °C, operated with a cooling circuit featuring external cryostats


process volume: 2.4 mL (total) and 1.7 mL (cooled)

can be partially dismantled

suitable for feasibility studies in the laboratory,

for process optimisation and for preclinical research

various plates for:

homogeneous reactions with excellent mixing

for gas-liquid and liquid-liquid systems

added functionality (i.e. multi-injections)

scale-up studies

combines the Lonza FlowPlate™ technology with the MMRS

for pilot and production-scale operations, we offer the

Lonza FlowPlate™ A6, A5 and A4 an (page 37)

process temperature: - 20 – 200 °C


process volume: 2 mL or 11 mL


fluidically temperature-controlled residence reactor with 2-mm-wide meander-shaped reaction channel

suitable for reactions in the liquid phase and of suspensions

for masterly handling of low-temperature reactions

with built-in, cooled LH 2 or cascade mixer to create a multi-functional integrated system

Residence reactor

Residence reactor

Residence reactor

reactor 100A4, HC

Art.-No. 0219-1

miprowa® labA4, HC

Art.-No. 0224-2

sandwich reactorA4, HC

Art.-No. 0213-1

flow inserts with slit widths in 2 mm and 0.8 mm

(others on request)

intensive, continuous cross-mixing of the process

medium in the channel



process volume: 30 mL (depending on the flow inserts)


fluidically temperature-controlled residence reactor with integrated static mixing function

particularly suitable for single- and multi-phase liquid-liquid and gas-liquid reactions

process temperature: -10 – 200 °C


process volume: 110 mL

fluidic temperature control

continuous mixing

milli-structured, compact residence reactor with a large internal volume and static mixing systems for lengthy residence times

for even larger process volumes in the MMRS, we offer the Reactor 450 on request

rectangular channels with flow inserts lead to excellent heat transfer and continuous mixing

for process development and optimisation, and for product development

particularly well suited for single and multi-phase liquid-liquid and gas-liquid reactions

combines the Miprowa® technology with the MMRS

the Miprowa® product grouping specialises in upscaling to flow rates of up to 10,000 L/h (page 38)

Residence reactor

Residence reactor

Residence reactor

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the geometry of the flow inserts can be used to adjust

pressure losses, mixing quality and heat transfer to suit the

particular process involved

process temperature: - 20 to 200 °C, with 2 integrated

Pt100 T-sensors; pressure up to 30 bar (at 25 °C)


replaceable flow inserts mean simple cleaning or also coating

with a catalyst

process volume: 30 mL with flow inserts; can (in dependence

on the inserts) be reduced by the user to 22.5, 15 or 7.5 mL

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cartridge reactor 240A4, HC

Art.-No. 0221-2

cartridge reactor 200HC

Art.-No. 0201-3

cylindrical cartridge can be easily removed and replaced

while the module is still installed

electric heating cartridges warm up the process fluid to

process temperature before it enters the cartridge

Pt100 temperature sensor measures the reaction

temperature in the fixed bed

process temperature: max. 200 °C, electrically heated


cartridge volume: 0.7 mL

for heterogeneously catalysed reactions with small catalyst quantities in a fixed bed

cylindrical cartridge can be easily removed and replaced while

the module is still installed

electric heating cartridges warm up the process fluid to process

temperature with 200 or 400 W before it enters the cartridge

process temperature: max. 240 °C

two Pt100 temperature sensors provide simultaneous measurement

of the temperature in the heating block and in the process fluid

directly at the outlet from the bulk material cartridge


cartridge volume: 5 mL (others on request)

for heterogeneously catalysed reactions in a fixed bed, particularly well suited

for single and multi-phase liquid-liquid and gas-liquid systems

photo-reactorA4, HC

Art.-No. 0226-2

good energetic efficiency and high spectral selectivity

homogeneous irradiation

layer thickness of the process channel can be adjusted

between 25 µm and 100 µm by simple modification

measures (other dimensions on request)

high-performance LEDs as a radiation source,

which are available in wavelengths with spectral widths

of approximately 20 nm

for out-of-the-ordinary requirements, we offer a special

UV lamp with a spectral filter or also LED arrays

liquid media are converted by irradiation in the ultraviolet and visible parts of the spectrum, e.g. halogenations and rearrangements

for higher flow rates, we offer our Photo-Reactor XL (page 43)

multifarious application options in the pharmaceutical industry, in the biotech sector,

and also in industrial and academic research and development

Photochemistry

Heterogeneous catalysis


Ht reactor UnitInconel

Art.-No. 0227-1

Fixed-bed meander reactorA4, HC

Art.-No. 0222-2

integrated reaction unit with preheating section, mixer,

fixed-bed reactor and fluidic cooling downstream

process temperature: max. 600 °C


cartridge volume: up to 5 mL

electrically heated

available in Alloy 600

As a prototype, the HT reactor unit is currently in the test phase. Its application category is

heterogeneous catalysis in a fixed bed at high temperatures – so it is particularly well suited for gas

phase reactions. Just get in touch with us – we’ll be pleased to tell you all about the test results.

fluidic temperature control even for reactions with marked

exothermy and at temperatures below room temperature

process temperature: - 20 to 200 °C


two Pt100 temperature sensors at the reactor’s inlet and

outlet provide close-to-process temperature measurement

process volume: 25 mL in the empty channel


particularly well suited for heterogeneously catalysed reactions with large catalyst quantities in a fixed bed

simple and convenient handling, since different radiation

sources from different vendors can be used

process temperature: 15 – 50 °C (others on request)

pressure up to 2.8 bar (at 25 °C)

irradiated process volume: 40 µl (25 µm layer thickness)

to 160 µl (100 µm layer thickness)





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Heat exchangerPlate Heat Exchanger Coax Heat Exchanger Heater Module

Base Plate Heater*

Art.-No. 0306 0309 0351 0830


fluidic fluidic electric electric

Dismantable – ✓ – not necessary

Heat transfer area 74 cm2 71 cm2 17 cm2 1,5 cm2 per raster unit

Remarkmodule with highest heat transfer area

low susceptibility to blockages

short response times, high pressure resistance

consistent temperature for entire set-up

Heat exchangersFor consistently getting the temperature right.

* See at page 30 (clamping components).

the core element is a diffusion-bonded stack of

micro-structured stainless steel foils

efficient heat transfer between the fluids

low residence volume

heat transfer coefficients (kA/V) of some 10 MW/m3

heat transfer area: 74 cm2

two Pt100 temperature sensors, at the inlet and outlet

channel respectively, provide close-to-process measurement

of the fluid temperature


with fluids that need to be fluidically temperature-controlled particularly fast or in a particularly small space

if only small differences are permissible between the target temperature and the temperature of the heat transfer medium

small channel dimensions are eminently suitable for particle-free fluids with a low viscosity

plate Heat exchangerA4 Type of temperature control: fluidic

Art.-No. 0306-2

This will probably no longer come as a surprise for you: our heat exchangers, too, are excellent. We have developed them specifically for the Modular MicroReaction System. The temperature control modules ensure very fast heat-up or cool-down – responsively and wherever this function is needed.

low susceptibility to blockages




low pressure drop

for temperature control of process fluids –

including those of higher viscosity or with particle loadings

compact construction: capillary helix soldered onto an electrically heated block of copper



two Pt100 temperature sensors – for the temperature of the heating block and

the temperature of the process fluid at the module outlet

pre-heater upstream of a mixer or reactor, if there is a need to avoid handling temperature control liquids

for defined electrical heating of a process fluid

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Heater moduleA4, HC Type of temperature control: electrical

Art.-No. 0351-3

coax Heat exchanger A4, HCType of temperature control: fluidic

Art.-No. 0309-4

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temperature sensorsA4, HC

Art.-No. 0501-2, 0502-2, 0503-1

pressure sensorsA4, HC

Art.-No. 0513-2, 0514-1, 0516-1

0503-10502-1

0516-10514-10513-1

0501-1

for temperature measurement in the fluid channel with a Pt100 sensor

enable additional measuring points to be provided at any desired positions in the system set-up

connection directions of 90° and 180° available

can be used at pressures of up to 100 bar

Sensors & actuatorsMore than instrumentation and control.

For smooth operation of the Modular MicroReaction System, other components are important too: sensors that measure pressure, temperature or flow rate, and transmit the information they acquire.

With the aid of actuators, the system then ensures that all process parameters can be optimally harmonised and regulated. And for you this means all systems go. Thanks not least to the intelligent automation solution: LabBox® (page 33), developed for the specific requirements encountered in a laboratory. You already have an automation system? No problem. The MMRS is uncomplicated in this regard as well.

for measuring the pressure in the fluid channel

for the following pressure ranges: 25 bar, 100 bar (others on request)

can be used at temperatures of up to 80 or 150 °C, depending on the model involved

back pressure regulator, mechanicalA4

Art.-No. 0609-1

mass Flow controller, thermal, for gasesA4

Art.-No. 0542-1

for dosing gas flows

integrated temperature compensation for volume flows of up to 30, 50 or 100 NL/h (others on request)

temperatures up to 65 °C

can be used at pressures of up to 40 or 60 bar, depending on the model involved

for manual pressure regulation in the MMRS

pressure adjustment using a setting wheel

pressure ranges: various models, max. 25 bar

can be used at temperatures of up to 80 or 200 °C, depending on the model involved

materials coming into contact with the fluid are stainless steel and FFKM or PEEK (others on request)

for pressure regulation at the outlet of the system

pressure controller, electronicA4

Art.-No. 0515-1

for automated pressure control in the MMRS

compact module with pressure sensor and pressure controller in stainless steel construction

pressure differential up to 40 bar

can be used at temperatures of up to 70 °C

as forward or back pressure controller available

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coriolis mass Flow controllerA4

Art.-No. 0546-1

optical Flow-through cellA4, HC

Art.-No. 0551-2

coriolis mass Flow meterA4

Art.-No. 0545-1

pH sensor and conductivity sensorA4

Art.-No. 0563-2

mass flow meter serves to monitor the substance flows

being used

can be used for both gases and liquids

enables the flow rate to be measured independently

of other physical characteristics

volume flow between 0.01 and 14 kg/h (water),

depending on the model involved

option for measuring the density of the substance flow


pressure: up to 30 or 100 bar,

depending on the model involved

for measuring

absorption and transmission in 180° geometry

fluorescence and scattered light in 90° geometry

contains a cuvette made of quartz glass and three

standard-SMA connections for linking up optical fibre cables

the Spectrobay® NIR process spectrometer from

Bayer Technology Services, for example, is well suited

for connection



mass flow controllers are used to regulate the substance flow to ensure a desired setpoint value,

for this purpose, a coriolis mass flow meter and a control valve are installed in a single module

volume flow is adjustable between 0.01 and 18.6 kg/h (water), depending on the model involved


pressure: up to 60 bar

for precise measurement of the pH value and conductivity in aqueous solutions

simple installation and removal of the standard electrodes

good wetting and long lifetime of the electrodes


pressure up to 4 bar (conductivity sensor) or 5 bar (pH sensor)

2- and 3-Way ball valveA4

Art.-No. 0605-2 Art.-No. 0606-2

relief valveA4

Art.-No. 0608-1

viscosity and density sensorA4

Art.-No. 0581-1

for measuring the viscosity and density of Newtonian liquids

viscosity measuring range: 0.3 – 100 mPas

density measuring range: 0 – 2,000 kg/m3

temperature range: - 20 – 110 °C, integrated temperature measurement


EhrfeldMikr

otechni

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limits the maximum operating pressure

for protecting pressure-sensitive parts of the system

enables pressure to be relieved in a piping or collecting system

can be responsively adjusted to suit the pressure conditions specified between 3.4 and 100 bar


for cut off of fluid branches inside the MMRS

manually operated


pressure up to 100 bar

0605-20606-2

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Links and connectionsFitting it all together.

An innovative technology will be successful only if everything is harmonised and fit for purpose down to the tiniest of details. The Modular MicroReaction System meets these requirements in full. To make sure that one module fits neatly into another we offer you a multitude of connection components that link pumps and thermostats snugly to the MMRS. And there’s a beneficial side-effect: the sealing plates avoid passive volumes between the microreaction modules almost entirely.

0703-1

0711-2

0704-1

0712-1

0705-2

0702-3

inlet / outlet, inlet with injector, direct outlet, t-inlet / outlet module, inlet / outlet 90°, Filter inletA4, HC

Art.-No. 0711-2, 0712-1, 0702-3, 0703-1, 0704-1, 0705-2

for supplying and removing the reactants in the MMRS

the direct outlet is particularly well suited for precipitation reactions, and can be installed downstream of the Valve Mixer 30 (page 15)

inlet modules with a replaceable filter prevent contamination or blockage of the microreaction setup due to entrained particles

the following connection types are available: 1/16”, 1/8” or 1/4” with Swagelok® or Valco® screw union

special connections, such as sanitary fittings (available on request)

0754-10751-2

0723-1 0726-1

0722-1

0724-1

0722-1

sealing plate, insulation sealing plate A4, HC

Art.-No. 0751-2, 0754-1

connection 90° and 180°, connection t-shape, connection x-shape, insulation moduleA4, HC

Art.-No. 0721-1, 0722-1, 0723-1, 0726-1, 0724-2

Sealing Plate

consists of an outer plate, the O-ring and an inner support ring

is installed between two modules with opposing fluid openings

can be positioned precisely on the base plate

Insulation Sealing Plate

consists of PEEK reinforced with carbon fibres, and possesses only a very small contact surface with the adjoining modules

reduces thermal conductivity between two adjoining modules

connection modules create a 90° or 180° link between two microreaction modules

the insulation module is used when two modules have to be operated at different temperatures

and the heat flow between the two of them is to be minimised

connection in T-Shape with three connections and X-Shape with four connections for simple branching

90° and 180° connection modules for additional geometrical degrees of freedom on the base plate

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Clamping componentsAll that’s needed is a single socket key.

To synergise the individual modules of our system into a perfectly functioning whole, you need clamping elements to assemble it. Our clamping modules render this step totally uncomplicated. All that’s needed is a hexagon socket key for pressure-tight clamping of the modules – it could hardly be simpler.

base platesSizes: A5, A4, A3, A2

Art.-No. 0811-1

serves as a carrier and positioning aid, on which all components of the Modular MicroReaction System can be flexibly mounted

divided into a square raster with individual cells measuring 25 x 25 mm

available in the following sizes: A5, A4, A3 and A2, modelled on DIN 476 for paper formats

made of aluminium

sturdy and easy to clean

clamping module Art.-No. 0821-3

base plate Heater Art.-No. 0830-2

for clamping the modules in place on the base plate, at each end of a module row (page 12)

pressure-proof and simple clamping by turning a knob

the housings of the clamping modules are made of aluminium

springs inside the clamping elements ensure a tight seal even in the event of thermal expansion

electrical heating plates, which can be screwed in place under the base plates of the MMRS

for even temperature control of the entire set-up

expands the application options of a system

ensures controlled electric heating of the base plate up to 200 °C

heat transfer area: 1.5 cm2 per raster unit

available for all standard base plates in the following sizes

A5: 8 × 6, A4: 12 × 8, A3: 16 × 12 und A2: 24 × 16 raster dimension

good thermal coupling of the modules to the base plate, since aluminium is used for the modules’ own bottom plates,

while the standard delivery package includes insulating bottom plates made of PEEK

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Automation systemSmart with LabBox®.

For the Modular MicroReaction System, we offer a responsively fit-for purpose automation solution in conjunction with Hitec Zang: a process automation system called LabBox®, which integrates all the requisite functions in a compactly dimensioned device – with well-nigh unlimited options. External individual components and the customary control cubicle are thus history.

LabBox® scores highly in terms of flexibility, performative excel-lence and exceptional user-friendliness. Because with the aid of the module library, developed exclusively for the MMRS, users enjoy the benefits of intuitive access: each module is depicted as a symbol on the software’s user interface – even the data point links have been preconfigured. LabBox® consists of a control unit and the associated visualisation and automation software package, called LabVision®. The modules of the Modular MicroReaction System can be connected to the interfaces of the control unit using special cables, responsively altered and supplemented at will, in this way, you can read out and control up to 100 data points. This is what smart instrumentation and control looks like nowadays.

salient data:

suitable for the Windows® 7, Vista, XP operating systems

meets the recommendations of the User Association for Automation Technology in the Process Industry (NAMUR)

designed for processes with frequent changes to the configuration

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The Lonza FlowPlate™ MicroReactor concept is acknowl-edged as on of the world’s leading design. It was devel-oped by the internationally operating life science company Lonza, and has won some rather prestigious prizes. Ehrfeld Mikrotechnik BTS is the exclusive distributor for Lonza FlowPlate™ MicroReactors worldwide. As the cooperation partner, we work together on marketing and design-enhancing this innovative microreactor concept: an easily scalable process technology for continuous pro-duction of fine chemicals and pharmaceuticals – which explains the accolades. We thus offer our customers in the pharmaceutical industry a fit-for purpose toolkit for putting in place tomorrow’s systems today.

From l abor atory to prodUct ionA concept that covers all the phases of a product’s life-cycle, from the tiniest laboratory scale in preclinical /clinical research, to pilot lines, and all the way through to commercial production, has been translated into engineered reality with the Lonza FlowPlate™ MicroReac-tors. They ensure quick and easy scale-up for developing active pharmaceutical ingredients (APIs) and production under cGMP conditions. Production measured in tons can be up and running within a few short weeks.

Lonza FlowPlate™ MicroReactorsAward-winning technology.

mixing structure sZ: for optimal plug flow

FlowPlate™ LabFlowPlate™ A6FlowPlate™ A5

material of the process plates: Hastelloy®

one cHannel – lots oF advantagesWhat’s innovative about the Lonza FlowPlate™ MicroReactors is their enclosed single-channel design – with significant advantages for your process:

volume flows from a laboratory scale of a few mL/min up to production rates of up to 40 L/h and more

quick and easy scale-up by channel upsizing under well-nigh constant process conditions

very high heat transfer capacity

simple process control

flexible adaptation for different reactions by fast replacement of process plates

safe handling of hazardous reagents

can be used up to a pressure of 100 bar

the concept eliminates passive volume, thus avoiding any residues inside the channel (cleaning in place)

easy cleaning and maintenance, ready for cGMP

To sum up: the compact and versatile design of the Lonza FlowPlate™ MicroReactors opens the way to innovative production concepts. And these in their turn lead to production lines for active ingredients and specialty chemicals, which can be very simply expanded and adapted using modularised components. This means that demand-responsive production and completely monitorable high-speed lines are no longer a vision for the future – they are reality. Here and now.

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mixing structure tg: for intensive backmixing

lonza Flowplatetm a5 for volume flows up to 30 liter per hour

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lonZ a FloWpl ate ™ l ab microre actorThis one is the smallest in the range, but is superbly equipped: the Lonza FlowPlate™ Lab is optimally suited for feasibility studies in the laboratory, for process development jobs and for preclinical research. The micro-structured process plate contains up to ten inlets and outlets along the process section, for concomitantly enhanced flexibility. A sight glass enables the flow processes involved to be visually monitored along the entire channel. To find the best version for your own particular process, these reactors can be run with different process plates, which can be easily replaced and manufactured to match your requirements precisely. We offer you the Lonza FlowPlate™ Lab MicroReactor in two different variants: as a stand-alone device or as a module for the MMRS (page 18). The dimensions are identical, just the connections are different.

standard type 1: multiinjection plate sZChannel: 0.6 x 0.5 mm2 Mixer nominal width: 0.2 mm Volume: 0.4 mL Connection points: 6

Art.-No. 1701-1642

process plate sZ

Channel: 5.0 x 0.5 mm2 Mixer nominal width: 0.25 mm Volume: 1.0 mL Connection points: 5

Art.-No. 1701-1501

standard type 2: multiinjection plate tgChannel: 0.6 x 0.5 mm2 Mixer nominal width: 0.2 mm Volume: 0.4 mL Connection points: 6

Art.-No. 1701-2642

process plate sZ


Art.-No. 1701-1301

multiinjection plate sZ


Art.-No. 1701-1341

multiinjection plate tg


Art.-No. 1701-2341

lonZ a FloWpl ate ™ a6 and a5 microre actors The range continues smoothly with the Lonza FlowPlate™ MicroReactors in the A6 and A5 sizes: they’re just as suitable for process development and research as for production under cGMP conditions on a pilot scale or for a product’s market launch. The design resembles that of the laboratory version: the process plates feature channel structures for mixing and residence volumes, which can be easily replaced to suit the ongoing requirements involved.

lonZ a FloWpl ate ™ a4 microre actor This model is currently still in the planning stage. Once it has reached maturity, the A4 MicroReactor will open up a whole new dimension for its users: because with this reactor, whose footprint is no larger than a sheet of notepaper, you can start on commercial manufacture of your product: under cGMP conditions and with flow rates of up to 40 kg/h. With its flexible adaptability to a multitude of different processes, its sturdy construction, plus simple cleaning and maintenance, the Lonza FlowPlate™ A4 constitutes a totally dependable, high-performance microreactor.

pre-heater plate

Channel: 5.0 x 0.5 mm2 Volume: 6.8 mL Connection points: 2 + 2

Art.-No. 1705-0201

process plate sZ

Channel: 10.0 x 0.5 mm2 Mischer-Nennweite: 0.7 mm Volume: 16.4 mL Connection points: 3

Art.-No. 1705-1111

process plate tg

Channel: 10.0 x 0.5 mm2 Mischer-Nennweite: 0.7 mm Volume: 16.5 mL Connection points: 3

Art.-No. 1705-2111

process plate

Channel: 10.0 x 0,5, 10.0 x 1.0, 10,0 x 2.0 mm2

Volume: 8.4, 16.7, 33.2 mL Connection points: 2

Art.-No. 1705-0101, 1705-0111, 1705-0121

These and many other process plates (e.g. with venturi nozzles for particularly fast mixing of gas and liquid, or customised designs for your application) are available for all Lonza FlowPlate™ models. Just ask us!

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Miprowa® high-performance reactors and heat exchangersRectangular does the trick.

Fast upscaling from ultra-small to production level under the same process conditions – with the innovative Miprowa® technology, this is engineered reality. These path-breaking, highly efficient reactors and heat exchangers are true masters when it comes to sophisticated temperature control jobs, since in comparison to conventional units they excel in terms of significantly higher heat transfer, thanks to their considerably larger surface-to-volume ratio. Another advantage of the Miprowa® technology is its continuous and intensive cross-mixing capability. Even scale transfers from one litre to high volume flows of up to 10,000 litres per hour pose no problems at all for these compactly dimensioned units.

Fle x ible l ayersThe secret of Miprowa® is its channels: they are not round, but rectangular in shape, relatively wide but not very high. Inside them are structured inserts that can be placed one on top of another in several layers to form a fine flat grid. Depending on the product requirement involved, the user can replace the easily withdrawn grids so as to influence heat transfer, pressure drops and mixing intensity.

Miprowa® channel with mixing inserts, view on the cross-section

miprowa® for volume flows up to

2,000 liter per hour

sma ll d imensions, gre at perFormanceMiprowa® channels and units score highly in terms of performative excellence: a milli-reactor or milli-heat exchanger is dimensionally smaller than a conventional shell-and-tube design. The Miprowa® Lab Reactor (page 19), with a channel cross-sectional area of 12 x 1.5 mm2, is optimally equipped for lab-scale operations. It is suitable for developing and optimising processes and equally appropriate for product development jobs. The larger Miprowa® units, designed for use in a pilot plant or a production line, have a cross-sectional area of 18 x 3 mm2, which ensures sturdy durability and easy cleaning whenever necessary. High flow rates can be achieved by connecting up to 1,000 channels in parallel instead of resorting to elaborate upscaling – as with a shell-and-tube design. We offer you the Miprowa® Lab in two variants: as a stand-alone device or as a module for the MMRS (page 19). The package also includes an integrated Pt100 temperature sensor for effective process monitoring in the channels.

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Double-comb insert DK 2241

Single-comb insert NK 1241

Standard type: Single-comb insert NK 2241

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eFFicacioUs tecHnology With our Miprowa® reactors, you optimise not only your engineered processes, but also your costs for equipment and energy consumption – while at the same time they are gentle on any sensitive materials, thanks to short residence times and low wall temperatures.

the miprowa® technology

we offer this as synergised units for use as continuously operated reactors or heat exchangers

technically designed to handle an operating pressure of up to 16 bar and operating temperatures of up to 200 °C (higher pressures and temperatures are possible on request)

uses standardised materials like stainless steel and Hastelloy® (others on request)

is optimally suited for exothermic and endothermic reactions, like nitration, hydrogenation or oxidation

can also be used for fast heating, cooling, condensing, evaporating

is already being used on an industrial scale, and is an attractive option for companies in the following industries: fine and specialty chemicals, petrochemicals, polymer chemistry, and the food, beverage and cosmetics industries

the miprowa® variants

Miprowa® Lab – high flexibility for the MMRS (page 19)

Miprowa® Matrix – our standard for laboratories and pilot plants

Miprowa® Production – customised for your own production process

modUl ar and smartMiprowa® apparatus are your key to smart production, because they can repeatedly be revamped to suit different requirements. We will most definitely have the right one for you. A special mixer, for instance, can be integrated for mixing gas-liquid flows with superb efficacy even before they enter the rectangular channel. An abundance of flange variants changes the basic unit to suit your particular process conditions. Sensors, too, can be easily integrated if precise monitoring of the temperature is required. We also offer our customers a maximised choice when it comes to coating any mixing inserts. For each reaction, we find the particular material you need, so that you can yourself coat the mixing inserts with a catalyst.

With the Miprowa® Matrix, we offer you a choice of standardised, quickly available units:

number of channels 1 3

Channel length Process volume*

300 mm 13 mL 38 mL

600 mm 19 mL 71 mL

1,200 mm 46 mL 136 mL

number of channels 1 3

Channel length Process volume*

300 mm 5 mL 14 mL

600 mm 8 mL 24 mL

1,200 mm 15 mL 45 mL

* Process volume will vary depending on the geometry of the flow inserts.

miprowa® matrix with 18 x 3.0 mm2 with standard type inserts (NK 2241)

miprowa® matrix with 12 x 1.5 mm2 with standard type inserts (NK 2241)

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valve mixer 300 A4, HC

Art.-No. 0121-1

volume flow up to 300 L/h

mixing plates available with different nominal slit diameters 130, 250 und 480 µm

innovative mixer type with one special feature: the non-return valve is able to largely prevent any backflow of the mixture

microstructures remain free of particle deposits, which in conventional types of mixer lead to blockages

suitable for continuous precipitation reactions, e.g. for producing catalyst particles or colour pigments

Special modelsFunction superbly alone as well.

You need tailormade equipment like a mixer, a reactor or a heat exchanger for a special application? Here, too, we have the right solutions. Like our easy-to-dismantle Gas Phase Reactor for catalyst coatings. Or our Photo-Reactor XL for light-induced reactions on a pilot scale.

Your requirements are even more specialised? No problem – we can make you customised equipment as well.

slit plate mixer lH 1000A4, HC

Art.-No. 0110-2

compact, sturdy construction using only a few components

easy to dismantle

quick and easy maintenance

different slit widths in the mixing and aperture plates for different mixing intensities

so far the largest model in the LH series of Slit Plate Mixers

suitable for production and large pilot-scale operations

for fast mixing of low-viscosity liquids with flow rates of a few 100 L/h up to a few 1,000 L/h with pressure drops of just a few bar

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Falling Film micro reactorA4, HC

Art.-No. 0218-1

gas phase reactorA4

Art.-No. 0254-1

photo-reactor xlA4, HC

Art.-No. 0206-1

good energetic efficiency and high spectral selectivity

homogeneous irradiation

layer thickness can be adjusted between 25 µm

and about 100 µm by simple modifications

(larger layer thicknesses on request)

high-performance LEDs as a radiation source, available in

wavelengths with spectral widths of approximately 20 nm

convenient and versatile in use, since radiation sources from

different vendors can be employed


liquid media are converted by irradiation in the ultraviolet and visible ranges of the spectrum

multifarious options for use in industrial and academic research and development,

e.g. in the pharmaceutical industry and in the biotech sector

for photocatalysis as well



empty volume: 36 mL

recommended volume flow for the liquid: 1 – 15 mL/min



features micro-structured stacks of plates, which can

be coated with a catalyst

the number of plates can be varied to suit the particular

reaction involved

process temperature: - 20 – 200 °C (others on request)


temperature-controlled process volume per layer: 2.4 mL



The Falling Film Micro Reactor serves to bring a flow of liquid into contact with a flow of gas under defined

temperature conditions without mixing the two process media involved. A prototype is currently in the test phase.

Just get in touch with us – we’ll be pleased to tell you all about the test results.

gas phase reactions

heterogeneously catalysed reactions at a wall catalyst

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Services & supportReassuringly responsive.

You’re familiar with our innovative products. But that’s not all that makes Ehrfeld Mikrotechnik BTS rather special. You have every right to expect more from a technology leader. And first of all there’s our team: experienced, highly qualified and supremely motivated, it includes engineers, scientists and sales experts, all of them tapping into our comprehensive corporate expertise. Both of these together constitute the foundation on which we successfully guide you into the fascinating world of microreaction technology. Here you benefit from our comprehensive spectrum of service support capabilities – an all-in-one convenience package.

We find solutions to your questions regarding

the deployment and utilisation of microreaction technology in your company

the right choice of modules and configurations from our Modular MicroReaction System, e.g. for developing products or optimising processes

the planning of your line and the development of specialised components

the composition of the system peripherals

scale-up to milli-structured production equipment

We are experts when it comes to r&d, and support you in our laboratory

with proof-of-principle studies for your investment decisions

by using microreaction technology to map out optimisation potentials

We are your reassuringly competent partner

for installing and configuring your laboratory or pilot system

for implementing microreaction technology in your production line

for basic and advanced training events

on a long-term basis as well, since we additionally assist you with after-sales, spares and product support

You need a customised solution? Fine. We develop micro- and milli-structured systems for the laboratory right up to full production scale – always precisely matched to your own specific job profiles.

Just get in touch with us.

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actuators 24fall-in-one solutions 04, 08, 44apparatus development 45areas of application 06, 10automatisation 10, 32Base Plate Heater 31catalysts 20, 40cGMP, CIP 06, 34Clamping Module 12, 31clamping system 12, 30fcleaning and maintenance 13, 16f, 35connectors 28fconstruction, MMRS 12, 30contact details 48custom-made 42, 45 development 04, 44dispersion 06, 12femulsification 06, 12fFalling Film Reactor 43Fixed-Bed Reactor 21Gas Phase Reactor 43heat exchanger dismantable 23 electrically heated 22f fluidically heated / cooled 22f, 38ff, 43 scalable 22, 38ffheat transfer area 22f heterogeneous catalysis 06, 20High Temperature Reactor 17, 21impact jet 15inlets 28lab scale 04, 10ffLabBox® 33

Lonza FlowPlate™ 08, 18, 34fMass Flow Controller 25fMass Flow Meter 26materials 10, 35, 40measurement, operation, control 24f, 32micro reaction technology 04Miprowa® 08, 19, 38fmixer 12f, 36f, 40 dismantable 14f scalable 10, 13ff temperature-controlled 13, 14, 36fModular MicroReaction System 10ffmulti-injection 18, 36multi-lamination 12foperating pressure Lonza FlowPlate™ 34f Miprowa® 38f MMRS 10ffoperating range Lonza FlowPlate™ 34f Miprowa® 38f MMRS 10ffoutlets 28particle precipitation 06, 13f passive volume 28, 35peripheral equipment 32, 44photochemistry 07, 20, 42Photo-Reactor 20, 42pilot scale 11, 34, 39f pressure range Lonza FlowPlate™ 34f Miprowa® 38f MMRS 10ff

Index

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Pressure Sensor 24process automatisation 33process development 04, 08process plates 34ffproduct groups 08production 11, 34f, 38f, 42fproof-of-principle studies 44pumps 44reactions 06 exothermic 06, 11 gas-liquid 06, 16, 34, 38 heterogeneous catalysis 06, 17, 20 liquid-liquid 06, 16, 34, 38 low temperature 06, 18 photo-induced 06, 20, 34reactors dismantable 16f electrically heated 16f fluidically heated/cooled 16f, 34f, 38f, 43 scalable 16f, 34f, 38f with mixing inserts 16f, 19, 38fresearch and development 04, 44residence reactor 16ff, 34ff, 38ffresidence times 16ffscalability 11, 13, 16f, 34f, 38fscale-up 11, 34, 38Sealing Plate 12, 28sensors 24f, 33service 08, 44spare parts 45special models 42split and recombine 12f

stand-alone 42static mixer 13f, 42surface-to-volume ratio 22, 38suspensions 12f, 16ftemperature range Lonza FlowPlate™ 18, 34f Miprowa® 19, 38f MMRS 10ffTemperature Sensor 24thermostats 44throughput, c.f. volume flow range training 44volume flow range Lonza FlowPlate™ 34f Miprowa® 38f MMRS 10ff

The specifications given relate in all cases to the product version detailed in the catalogue and current at the time of printing (status June 2012), and may differ in the case of future versions. We reserve the right to changes and errors. Illustrations and drawings are only approximately determinant.

Ehrfeld Mikrotechnik BTS GmbHMikroforum Ring 155234 Wendelsheim, GermanyPhone +49 (0)6734 919 300Fax +49 (0)6734 919 [email protected]

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Innovative. Flexible. Efficient. - DKSH...like mixers, reactors and heat exchangers to be conveniently mounted and re-arranged at will, for maximised flexibility. If you think it resem-bles