2006

Organo-phosphorus compoundsS 0080 Inhibition of Trypsin and Urokinase by Cbz-Amino(4-guanidinophenyl)methane-

phosphonate Aromatic Ester Derivatives: The Influence of the Ester Group on Their Biological Activity. — The synthesis of compound (I), the most potent phos-phonic inhibitor of urokinase plasminogen activator (uPA) prepared to date, is reported. — (SIENCZYK, M.; OLEKSYSZYN*, J.; Bioorg. Med. Chem. Lett. 16 (2006) 11, 2886-2890; Div. Med. Chem. Microbiol., Fac. Chem., Wroclaw Univ. Technol., PL-53-570 Wroclaw, Pol.; Eng.) — C. Oppel

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